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The map label for this gene is bcd [H]

Identifier: 94312659

GI number: 94312659

Start: 269270

End: 270469

Strand: Direct

Name: bcd [H]

Synonym: Rmet_3727

Alternate gene names: 94312659

Gene position: 269270-270469 (Clockwise)

Preceding gene: 94312657

Following gene: 94312660

Centisome position: 10.44

GC content: 67.17

Gene sequence:

>1200_bases
ATGGATTTCCGACCCGACCCCAGCCTGCAGGCATTCCGGCAGGAGGTGCGCGAGTTCCTGCGCGAGAGTCTTCCCCCCGA
CCTGCCGCGCCGCAAGGGTGGCTTTCGCTCCCCACGCGCGGATTTGGCCCGCTGGCAGGGGATCCTGCACGCCAAGGGCT
GGGGCGCGCCGTACTGGGCCAGCGAGCACGGCGGTACCGGCTGGACCGTGCCGCAGCGGCTGATCTTCGACGAGGAGTGC
AGCGCCGCGGGCGCGCCGACGCAGGATGGCTTCGCGCAGAAGCTGGTGGGGCCCGTGCTGAACTATTTCGCGACGCCGGA
GCAGCGGGCCGCCCACGTGCCGGCGATTCTCGCCGGAAAGCGGATGTGGTGTCAGGGCTTCTCCGAGCCGGGTTCCGGGT
CGGATCTCGCTTCGTTGCGGACCCGCGCCGAGCGCGATGGCGATCACTACGTCGTCAATGGTCAGAAGATCTGGACCAGC
TATGGGCATGAGGCCGACTGGATCTTTCTGCTGGTGCGTACCGACACGCAGGTGAAGAAGCAGGCCGGGATCAGTTTCCT
GCTGGTGGACATGAAGACGCCAGGCATCACCGTGCGGCCGATCATCAGCATCGACGGCGCGCATCATCTGAACGAGACGT
TCTTCGAGGACGTACGGGTACCCGTGAGCAACCTCGTCGGCGCCGAGGGCGAGGGGTGGAAGCTCACCAAGTTCCTGCTC
AATAACGAGCACGCGTCGACGGCGGACCTGCCGACGCTGCAGCGATTCCAGCGGCAATTGCGTGCGTTGGCTGCCACGCG
GGGGGCGGGCGGCGGGACCTTGATCGGCCGGCACGAATTTGCCCTGCGCCTGGCGCGCCTGGAGGCCGAGTTGCAGGCGA
TCACGGTGATGGTGCAGCGTGTGGCGGCCATGGAGGCGGACCATAGTCCCGCCGCTCACGCGATGGGTTCGATCCTCAAG
GTGCGAGGTACCGAGCTGCAGCAGAAGATGAGCGAGTTCCTTGTCGAGGCGCTCGGCGACCATGGCGCGGTGGCGTATCC
GGGATCGCACGCGGCCACGGCAGGCGCCCGGTCGCTGCCGATGCAGGAGGTGGCGCAGTCCATCGCGGCCGACATGCTCT
TCCGGCGGGCCACCACGATCTACGGTGGTACCAGCGAAGTGCAGCGCGGCATCATCGCCAAGTCGCTGTTTCAGTTCTGA

Upstream 100 bases:

>100_bases
GGCCTGGCGCATATTGGCCCCCCCACCAGTAGCGGGGGGCTGTCTTTCAACGTCTGGCCGCTTACTGTGAAGTCCATTGG
CTTGATCAGGAGAGCTTCAG

Downstream 100 bases:

>100_bases
CCCGACACGAGTGTTCCATATCCATGCATTTCAAGCTGAATGATGCGCAGCAAATGCTGCAGGACAGCGCCCGCCGCTTC
GTCGAGAAGGCATATGCATT

Product: putative acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MDFRPDPSLQAFRQEVREFLRESLPPDLPRRKGGFRSPRADLARWQGILHAKGWGAPYWASEHGGTGWTVPQRLIFDEEC
SAAGAPTQDGFAQKLVGPVLNYFATPEQRAAHVPAILAGKRMWCQGFSEPGSGSDLASLRTRAERDGDHYVVNGQKIWTS
YGHEADWIFLLVRTDTQVKKQAGISFLLVDMKTPGITVRPIISIDGAHHLNETFFEDVRVPVSNLVGAEGEGWKLTKFLL
NNEHASTADLPTLQRFQRQLRALAATRGAGGGTLIGRHEFALRLARLEAELQAITVMVQRVAAMEADHSPAAHAMGSILK
VRGTELQQKMSEFLVEALGDHGAVAYPGSHAATAGARSLPMQEVAQSIAADMLFRRATTIYGGTSEVQRGIIAKSLFQF

Sequences:

>Translated_399_residues
MDFRPDPSLQAFRQEVREFLRESLPPDLPRRKGGFRSPRADLARWQGILHAKGWGAPYWASEHGGTGWTVPQRLIFDEEC
SAAGAPTQDGFAQKLVGPVLNYFATPEQRAAHVPAILAGKRMWCQGFSEPGSGSDLASLRTRAERDGDHYVVNGQKIWTS
YGHEADWIFLLVRTDTQVKKQAGISFLLVDMKTPGITVRPIISIDGAHHLNETFFEDVRVPVSNLVGAEGEGWKLTKFLL
NNEHASTADLPTLQRFQRQLRALAATRGAGGGTLIGRHEFALRLARLEAELQAITVMVQRVAAMEADHSPAAHAMGSILK
VRGTELQQKMSEFLVEALGDHGAVAYPGSHAATAGARSLPMQEVAQSIAADMLFRRATTIYGGTSEVQRGIIAKSLFQF
>Mature_399_residues
MDFRPDPSLQAFRQEVREFLRESLPPDLPRRKGGFRSPRADLARWQGILHAKGWGAPYWASEHGGTGWTVPQRLIFDEEC
SAAGAPTQDGFAQKLVGPVLNYFATPEQRAAHVPAILAGKRMWCQGFSEPGSGSDLASLRTRAERDGDHYVVNGQKIWTS
YGHEADWIFLLVRTDTQVKKQAGISFLLVDMKTPGITVRPIISIDGAHHLNETFFEDVRVPVSNLVGAEGEGWKLTKFLL
NNEHASTADLPTLQRFQRQLRALAATRGAGGGTLIGRHEFALRLARLEAELQAITVMVQRVAAMEADHSPAAHAMGSILK
VRGTELQQKMSEFLVEALGDHGAVAYPGSHAATAGARSLPMQEVAQSIAADMLFRRATTIYGGTSEVQRGIIAKSLFQF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI187960098, Length=349, Percent_Identity=28.080229226361, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI4557231, Length=349, Percent_Identity=28.080229226361, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI4557233, Length=399, Percent_Identity=27.5689223057644, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI7656849, Length=351, Percent_Identity=26.7806267806268, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4501857, Length=405, Percent_Identity=27.1604938271605, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI226958412, Length=398, Percent_Identity=25.3768844221106, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI226958414, Length=369, Percent_Identity=24.9322493224932, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4501859, Length=235, Percent_Identity=28.0851063829787, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4557235, Length=371, Percent_Identity=29.1105121293801, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI76496475, Length=371, Percent_Identity=29.1105121293801, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI21361497, Length=256, Percent_Identity=27.734375, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI38505218, Length=150, Percent_Identity=31.3333333333333, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI211971008, Length=309, Percent_Identity=24.2718446601942, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI48976061, Length=309, Percent_Identity=24.2718446601942, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87081958, Length=238, Percent_Identity=24.3697478991597, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17570075, Length=413, Percent_Identity=26.8765133171913, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17569725, Length=363, Percent_Identity=27.2727272727273, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17534899, Length=411, Percent_Identity=25.5474452554745, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17538396, Length=397, Percent_Identity=27.7078085642317, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17533517, Length=350, Percent_Identity=23.4285714285714, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71985184, Length=148, Percent_Identity=37.8378378378378, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17551932, Length=280, Percent_Identity=25, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=148, Percent_Identity=37.8378378378378, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17508101, Length=340, Percent_Identity=25, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=392, Percent_Identity=25, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=248, Percent_Identity=24.5967741935484, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=184, Percent_Identity=29.3478260869565, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71990804, Length=184, Percent_Identity=28.804347826087, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21355753, Length=235, Percent_Identity=30.2127659574468, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24660351, Length=301, Percent_Identity=26.9102990033223, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24666513, Length=347, Percent_Identity=26.2247838616715, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281363737, Length=370, Percent_Identity=27.5675675675676, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21356377, Length=400, Percent_Identity=26, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646207, Length=405, Percent_Identity=25.1851851851852, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 43759; Mature: 43759

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFRPDPSLQAFRQEVREFLRESLPPDLPRRKGGFRSPRADLARWQGILHAKGWGAPYWA
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCC
SEHGGTGWTVPQRLIFDEECSAAGAPTQDGFAQKLVGPVLNYFATPEQRAAHVPAILAGK
CCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCHHHHCC
RMWCQGFSEPGSGSDLASLRTRAERDGDHYVVNGQKIWTSYGHEADWIFLLVRTDTQVKK
HHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCEEEEECCCCCCCEEEEEEECCHHHHH
QAGISFLLVDMKTPGITVRPIISIDGAHHLNETFFEDVRVPVSNLVGAEGEGWKLTKFLL
HCCCEEEEEEECCCCEEEEEEEEECCCHHHHHHHHHHHHCCHHHHCCCCCCCCEEHHHHH
NNEHASTADLPTLQRFQRQLRALAATRGAGGGTLIGRHEFALRLARLEAELQAITVMVQR
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
VAAMEADHSPAAHAMGSILKVRGTELQQKMSEFLVEALGDHGAVAYPGSHAATAGARSLP
HHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEECCCCCHHCCCCCCCC
MQEVAQSIAADMLFRRATTIYGGTSEVQRGIIAKSLFQF
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFRPDPSLQAFRQEVREFLRESLPPDLPRRKGGFRSPRADLARWQGILHAKGWGAPYWA
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCC
SEHGGTGWTVPQRLIFDEECSAAGAPTQDGFAQKLVGPVLNYFATPEQRAAHVPAILAGK
CCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCHHHHCC
RMWCQGFSEPGSGSDLASLRTRAERDGDHYVVNGQKIWTSYGHEADWIFLLVRTDTQVKK
HHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCEEEEECCCCCCCEEEEEEECCHHHHH
QAGISFLLVDMKTPGITVRPIISIDGAHHLNETFFEDVRVPVSNLVGAEGEGWKLTKFLL
HCCCEEEEEEECCCCEEEEEEEEECCCHHHHHHHHHHHHCCHHHHCCCCCCCCEEHHHHH
NNEHASTADLPTLQRFQRQLRALAATRGAGGGTLIGRHEFALRLARLEAELQAITVMVQR
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
VAAMEADHSPAAHAMGSILKVRGTELQQKMSEFLVEALGDHGAVAYPGSHAATAGARSLP
HHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEECCCCCHHCCCCCCCC
MQEVAQSIAADMLFRRATTIYGGTSEVQRGIIAKSLFQF
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]