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The map label for this gene is ychM [C]

Identifier: 94312652

GI number: 94312652

Start: 259797

End: 261557

Strand: Direct

Name: ychM [C]

Synonym: Rmet_3720

Alternate gene names: 94312652

Gene position: 259797-261557 (Clockwise)

Preceding gene: 94312651

Following gene: 291481483

Centisome position: 10.07

GC content: 65.7

Gene sequence:

>1761_bases
ATGCTATCCGACGGCCGCAACCCAGGCGCCTCGCGTAAAGCGCGGATCCCCAATTCCTGGCTGCGATGGCTGCCGGGCGT
GGCGATGGCCCGGGACTACCAGGCAAGCTGGCTGCCACGGGACCTGACGGCGGGGCTGGTCCTGACGACGATGCTCGTGC
CGGTTGGCATTGCCTATGCGGAAGCGTCAGGTGTGCCAGGCGTCTACGGCCTCTACGCGACCATCGTGCCGCTGCTTGCC
TATGCGGTATTCGGCCCCAGCAGGATTCTCGTGCTCGGCCCCGATTCGGCGCTGGCGGCGCCGGTGCTTGCAGTGGTCGT
CCAGATGTCCGGTGGTGATCCGGCGCGCGCGATCGCGGTGGCCAGCATGATGGCGATCGTCTCGGGGCTGTTCTGCATCG
TCATGGGTCTGCTGCGGCTGGGCTTTATCACCGAGCTGCTGTCCAAGCCGATCCGCTACGGCTACATGAACGGGATTGCG
TTCACGGTGCTGGTCAGCCAGTTGCCGAAGATCTTCGCCATCCGTGTGGAGGACACCGGGCCGTTGCGGGAACTGGTGCT
GTTGGGCCAGGCGCTGGTTGCTGGCCAGGTCAACTGGTATAGCGCCGCGGTTGGGGCAGGTAGCCTGGTGCTGATCCTCG
CGCTCAAGCGTTTCGAACGCGTGCCGGGCATCCTGATAGCGGTGATCGTGGCAACGCTGTGCGTGATCATGTTCGACCTG
GACCAGATGGGTGTGAAGGTGCTGGGTTCGATCCCGCAGGGTTTGCCGGCCTTCGCGGTGCCCTGGGCCAGCGGTCTCGA
CTTCGTCAAGATCGTGGCGGGTGGCTGCGCCGTGGCAATGATCGCCTTCGCGGATACCAGTGTGCTGTCCCGCAGCTTCG
CGGCCCGGCACCATCACCGCGTGGACCCGAACCAGGAGATGGTTGGCCTTGGCGCCGCCAATCTCGCCGCGGGCTTTTTC
CAGGGCTTCCCGATCAGCAGCAGCGCGTCACGCACGCCGGTGGCCGAGGCGGCCGGCGCGCGGACCCAGTTGACTGGCGT
GGTGGGCGCGCTGGCTGTCGCGGCGCTGCTGGTGGTGGCGCCTGACCTGATGCGCTATCTGCCAAACAGCGCGCTCGCGG
CAGTGGTGATTGCCGCCGCGCTGGGGTTGTTCGAGTTCGCGGATCTGAAGCGGATCTATCGCATCCAGCAATGGGAGTTC
TGGCTCTCGATGGTCTGCTTCGTGGCGGTTGCCGTGTTCGGTGCGATTCCCGGCATCGGCCTTGCGGTGGTGCTCGCCAT
TATCGAATTCCTTTGGGACGGCTGGCGACCCCACTACGCGATACTCGGACAAGTCGAGGGCCTGCGCGGCTACCATGACC
TGGAGCGCTATCCGCACGGCAAGCGGATTCCCGGGCTTGTGCTGTTCCGTTGGGATGCCCCGTTATTCTTTGCCAATGCC
GAGCTGTTCCAGGAACGCCTGCAGGAGGCGATCGACGAGTCTCCAGCCCCCGTGTATCGCGTGGTGGTGGCCGCGGAGCC
GGTGACCAGTGTGGATGTGACGTCCGCCGACATGCTGCGCGAGCTGAGTCGCACACTGGGCGAGCACGGTATCGCCCTGC
ATTTCGCGGAGATGAAGGACCCGGTCCGTGACAAGCTGCGGCGCTTCGAACTGATGGACGTGATCGGCGAGGACCGCTTT
CACCCGACGGTGGGCAGCGCGGTGGATGACTATGTCGGCCGGCAGGGAGACTGGCCGGAAGCGTGGGGCCGGAACGAGTA
G

Upstream 100 bases:

>100_bases
TAGTCGCGCGGTATTGATGATCCACATCTATGCTTAGGGATGTATGGCCATGTCTTGCCGAATCCCCACGGTGCATCGCA
ACTAGAAAAGAGGACCGACC

Downstream 100 bases:

>100_bases
GGTGGGGTGATTGAAACAGCGCGCGACGCGGAGAGACTGCCCACGCTGCGCGGATACAGGCACAAGCACAGGCGCCGTGG
CGGCGCCCGTACCTGTCAGT

Product: sulfate transporter (permease)

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MLSDGRNPGASRKARIPNSWLRWLPGVAMARDYQASWLPRDLTAGLVLTTMLVPVGIAYAEASGVPGVYGLYATIVPLLA
YAVFGPSRILVLGPDSALAAPVLAVVVQMSGGDPARAIAVASMMAIVSGLFCIVMGLLRLGFITELLSKPIRYGYMNGIA
FTVLVSQLPKIFAIRVEDTGPLRELVLLGQALVAGQVNWYSAAVGAGSLVLILALKRFERVPGILIAVIVATLCVIMFDL
DQMGVKVLGSIPQGLPAFAVPWASGLDFVKIVAGGCAVAMIAFADTSVLSRSFAARHHHRVDPNQEMVGLGAANLAAGFF
QGFPISSSASRTPVAEAAGARTQLTGVVGALAVAALLVVAPDLMRYLPNSALAAVVIAAALGLFEFADLKRIYRIQQWEF
WLSMVCFVAVAVFGAIPGIGLAVVLAIIEFLWDGWRPHYAILGQVEGLRGYHDLERYPHGKRIPGLVLFRWDAPLFFANA
ELFQERLQEAIDESPAPVYRVVVAAEPVTSVDVTSADMLRELSRTLGEHGIALHFAEMKDPVRDKLRRFELMDVIGEDRF
HPTVGSAVDDYVGRQGDWPEAWGRNE

Sequences:

>Translated_586_residues
MLSDGRNPGASRKARIPNSWLRWLPGVAMARDYQASWLPRDLTAGLVLTTMLVPVGIAYAEASGVPGVYGLYATIVPLLA
YAVFGPSRILVLGPDSALAAPVLAVVVQMSGGDPARAIAVASMMAIVSGLFCIVMGLLRLGFITELLSKPIRYGYMNGIA
FTVLVSQLPKIFAIRVEDTGPLRELVLLGQALVAGQVNWYSAAVGAGSLVLILALKRFERVPGILIAVIVATLCVIMFDL
DQMGVKVLGSIPQGLPAFAVPWASGLDFVKIVAGGCAVAMIAFADTSVLSRSFAARHHHRVDPNQEMVGLGAANLAAGFF
QGFPISSSASRTPVAEAAGARTQLTGVVGALAVAALLVVAPDLMRYLPNSALAAVVIAAALGLFEFADLKRIYRIQQWEF
WLSMVCFVAVAVFGAIPGIGLAVVLAIIEFLWDGWRPHYAILGQVEGLRGYHDLERYPHGKRIPGLVLFRWDAPLFFANA
ELFQERLQEAIDESPAPVYRVVVAAEPVTSVDVTSADMLRELSRTLGEHGIALHFAEMKDPVRDKLRRFELMDVIGEDRF
HPTVGSAVDDYVGRQGDWPEAWGRNE
>Mature_586_residues
MLSDGRNPGASRKARIPNSWLRWLPGVAMARDYQASWLPRDLTAGLVLTTMLVPVGIAYAEASGVPGVYGLYATIVPLLA
YAVFGPSRILVLGPDSALAAPVLAVVVQMSGGDPARAIAVASMMAIVSGLFCIVMGLLRLGFITELLSKPIRYGYMNGIA
FTVLVSQLPKIFAIRVEDTGPLRELVLLGQALVAGQVNWYSAAVGAGSLVLILALKRFERVPGILIAVIVATLCVIMFDL
DQMGVKVLGSIPQGLPAFAVPWASGLDFVKIVAGGCAVAMIAFADTSVLSRSFAARHHHRVDPNQEMVGLGAANLAAGFF
QGFPISSSASRTPVAEAAGARTQLTGVVGALAVAALLVVAPDLMRYLPNSALAAVVIAAALGLFEFADLKRIYRIQQWEF
WLSMVCFVAVAVFGAIPGIGLAVVLAIIEFLWDGWRPHYAILGQVEGLRGYHDLERYPHGKRIPGLVLFRWDAPLFFANA
ELFQERLQEAIDESPAPVYRVVVAAEPVTSVDVTSADMLRELSRTLGEHGIALHFAEMKDPVRDKLRRFELMDVIGEDRF
HPTVGSAVDDYVGRQGDWPEAWGRNE

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=504, Percent_Identity=27.9761904761905, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI39752683, Length=504, Percent_Identity=27.9761904761905, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI94721253, Length=494, Percent_Identity=31.3765182186235, Blast_Score=210, Evalue=3e-54,
Organism=Homo sapiens, GI94721255, Length=494, Percent_Identity=31.3765182186235, Blast_Score=210, Evalue=4e-54,
Organism=Homo sapiens, GI94721259, Length=494, Percent_Identity=31.3765182186235, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI94721257, Length=494, Percent_Identity=31.3765182186235, Blast_Score=209, Evalue=6e-54,
Organism=Homo sapiens, GI269784651, Length=503, Percent_Identity=26.2425447316103, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI4557535, Length=517, Percent_Identity=27.0793036750484, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI4505697, Length=526, Percent_Identity=26.9961977186312, Blast_Score=169, Evalue=8e-42,
Organism=Homo sapiens, GI45827802, Length=446, Percent_Identity=27.3542600896861, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI47131207, Length=644, Percent_Identity=27.4844720496894, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI20336272, Length=644, Percent_Identity=27.4844720496894, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI100913030, Length=618, Percent_Identity=25.0809061488673, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI262206105, Length=606, Percent_Identity=26.0726072607261, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI262206075, Length=606, Percent_Identity=26.0726072607261, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI262206069, Length=606, Percent_Identity=26.0726072607261, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI262206063, Length=606, Percent_Identity=26.0726072607261, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI217272867, Length=504, Percent_Identity=24.4047619047619, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI16418413, Length=515, Percent_Identity=24.2718446601942, Blast_Score=129, Evalue=9e-30,
Organism=Homo sapiens, GI16418457, Length=535, Percent_Identity=22.9906542056075, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI301601599, Length=535, Percent_Identity=22.9906542056075, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI16306483, Length=518, Percent_Identity=24.1312741312741, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI20336282, Length=518, Percent_Identity=24.1312741312741, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI65506789, Length=375, Percent_Identity=28.2666666666667, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI301601602, Length=214, Percent_Identity=25.7009345794392, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI45827804, Length=262, Percent_Identity=24.4274809160305, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI87081859, Length=516, Percent_Identity=26.1627906976744, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562578, Length=643, Percent_Identity=26.5940902021773, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI86564196, Length=640, Percent_Identity=25.15625, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17551690, Length=593, Percent_Identity=25.4637436762226, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17566848, Length=602, Percent_Identity=25.5813953488372, Blast_Score=186, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI86565215, Length=595, Percent_Identity=23.8655462184874, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI193203292, Length=516, Percent_Identity=24.4186046511628, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI86564876, Length=679, Percent_Identity=21.9440353460972, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI86565213, Length=285, Percent_Identity=27.3684210526316, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI86565209, Length=245, Percent_Identity=25.3061224489796, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI86565211, Length=245, Percent_Identity=25.3061224489796, Blast_Score=85, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323121, Length=478, Percent_Identity=26.7782426778243, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6325260, Length=581, Percent_Identity=20.9982788296041, Blast_Score=130, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6319771, Length=477, Percent_Identity=24.3186582809224, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24666186, Length=552, Percent_Identity=26.4492753623188, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24649801, Length=584, Percent_Identity=23.972602739726, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI85815873, Length=538, Percent_Identity=24.5353159851301, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24647160, Length=551, Percent_Identity=23.5934664246824, Blast_Score=129, Evalue=8e-30,
Organism=Drosophila melanogaster, GI21355087, Length=551, Percent_Identity=23.7749546279492, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI19922482, Length=539, Percent_Identity=24.1187384044527, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24651449, Length=595, Percent_Identity=22.3529411764706, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI21358633, Length=567, Percent_Identity=23.8095238095238, Blast_Score=125, Evalue=9e-29,
Organism=Drosophila melanogaster, GI21358229, Length=554, Percent_Identity=22.9241877256318, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24663084, Length=565, Percent_Identity=22.4778761061947, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357695, Length=565, Percent_Identity=22.4778761061947, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 63009; Mature: 63009

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSDGRNPGASRKARIPNSWLRWLPGVAMARDYQASWLPRDLTAGLVLTTMLVPVGIAYA
CCCCCCCCCCCCCCCCCHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EASGVPGVYGLYATIVPLLAYAVFGPSRILVLGPDSALAAPVLAVVVQMSGGDPARAIAV
HCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHH
ASMMAIVSGLFCIVMGLLRLGFITELLSKPIRYGYMNGIAFTVLVSQLPKIFAIRVEDTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
PLRELVLLGQALVAGQVNWYSAAVGAGSLVLILALKRFERVPGILIAVIVATLCVIMFDL
HHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DQMGVKVLGSIPQGLPAFAVPWASGLDFVKIVAGGCAVAMIAFADTSVLSRSFAARHHHR
HHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VDPNQEMVGLGAANLAAGFFQGFPISSSASRTPVAEAAGARTQLTGVVGALAVAALLVVA
CCCCCHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHH
PDLMRYLPNSALAAVVIAAALGLFEFADLKRIYRIQQWEFWLSMVCFVAVAVFGAIPGIG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LAVVLAIIEFLWDGWRPHYAILGQVEGLRGYHDLERYPHGKRIPGLVLFRWDAPLFFANA
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEEEECCCEEECCH
ELFQERLQEAIDESPAPVYRVVVAAEPVTSVDVTSADMLRELSRTLGEHGIALHFAEMKD
HHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHCC
PVRDKLRRFELMDVIGEDRFHPTVGSAVDDYVGRQGDWPEAWGRNE
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLSDGRNPGASRKARIPNSWLRWLPGVAMARDYQASWLPRDLTAGLVLTTMLVPVGIAYA
CCCCCCCCCCCCCCCCCHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EASGVPGVYGLYATIVPLLAYAVFGPSRILVLGPDSALAAPVLAVVVQMSGGDPARAIAV
HCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHH
ASMMAIVSGLFCIVMGLLRLGFITELLSKPIRYGYMNGIAFTVLVSQLPKIFAIRVEDTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
PLRELVLLGQALVAGQVNWYSAAVGAGSLVLILALKRFERVPGILIAVIVATLCVIMFDL
HHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DQMGVKVLGSIPQGLPAFAVPWASGLDFVKIVAGGCAVAMIAFADTSVLSRSFAARHHHR
HHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VDPNQEMVGLGAANLAAGFFQGFPISSSASRTPVAEAAGARTQLTGVVGALAVAALLVVA
CCCCCHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHH
PDLMRYLPNSALAAVVIAAALGLFEFADLKRIYRIQQWEFWLSMVCFVAVAVFGAIPGIG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LAVVLAIIEFLWDGWRPHYAILGQVEGLRGYHDLERYPHGKRIPGLVLFRWDAPLFFANA
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEEEECCCEEECCH
ELFQERLQEAIDESPAPVYRVVVAAEPVTSVDVTSADMLRELSRTLGEHGIALHFAEMKD
HHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHCC
PVRDKLRRFELMDVIGEDRFHPTVGSAVDDYVGRQGDWPEAWGRNE
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]