Click here to switch to the map view.

The map label for this gene is ltrA [H]

Identifier: 94312651

GI number: 94312651

Start: 258805

End: 259713

Strand: Direct

Name: ltrA [H]

Synonym: Rmet_3719

Alternate gene names: 94312651

Gene position: 258805-259713 (Clockwise)

Preceding gene: 94312648

Following gene: 94312652

Centisome position: 10.03

GC content: 66.12

Gene sequence:

>909_bases
ATGAGATTGCTTCAGGAACTCGATATTTTCGTGCGCACCGCCGATAACGGCAGCCTGTCCGCCACCGCGCGGGCGCTGGA
CCTGACGCCGGCGGCCACCAGCGCGGCGCTCAAGCGGCTGGAAGGCGAACTGGGCGTCCAGTTGTTCGTGCGCTCCACAC
GCACGATGCGGCTGACCCGCGAGGGCGAGCAGTACCTGGCGCAATGCCGGCCCGCGCTCGAGGTGCTGCAGCAGGCAAGC
CGGGATCTGCTCACCGGCAACCAGGCGTTCCAGGGCGTGGTCAGGTTGTCGGCCCCGTCTGACTTCGGACGCAACCTGCT
GCTGCCCTGGCTCGATGCGTTCCAGGACCGCCATCCCCTGGTCGAATTCCGGCTGCAGTTGACGGATCGCATGGCGAATA
TCTACAGCGATCCCGTCGACGTGGCCTTCCGTTATGGTGAGCCGCCGGATTCGAATCTCGTGGCGGTGCCGGTGGCAACG
GGCATCCACAGGGTGCTATGCGCTTCGCCGGGCTATCTCGCCAGTCACGACATGCCGCAAACGCCATATGACCTGTCCGC
GCATCGCTGTCTCTGCTACATGTTTGGCGATGACGTGCATGATCGCTGGCGCTTCGCGCGCGAAGACGGCGAGACACTGA
CCGTGCGCGTCAAGCCGGCCAATGTTTCGAACGATGGGGACGCCGTGCGCCGCTGGGCGCTGGCCGGCAAGGGCATCGCC
TACAAGGCCTGGTTCGATGTGGCCGACGATCTCGCGGCGGGTCGCCTGCGTGCGTTGTGCACCGCGTGGACGGCCGAAGC
ATCGCCGCTGTACATGGTCGTGGCGGGGCGTTCGCAACTGACGCCGCTGCTGCGCGGGTTGCGCGATTTCGTGGCCGAAC
GGGTGGAGCGACTAGTCGCGCGGTATTGA

Upstream 100 bases:

>100_bases
GATCCCACTACGCAGTCGATTGAAAAACTGGGCTTCACTTGTACCCGTATTCAAATAAAATTTGAAGATCACCTCAGATC
GGCCCTGTGCCTCGACGCCC

Downstream 100 bases:

>100_bases
TGATCCACATCTATGCTTAGGGATGTATGGCCATGTCTTGCCGAATCCCCACGGTGCATCGCAACTAGAAAAGAGGACCG
ACCATGCTATCCGACGGCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>_residues

Sequences:

>Translated_302_residues
MRLLQELDIFVRTADNGSLSATARALDLTPAATSAALKRLEGELGVQLFVRSTRTMRLTREGEQYLAQCRPALEVLQQAS
RDLLTGNQAFQGVVRLSAPSDFGRNLLLPWLDAFQDRHPLVEFRLQLTDRMANIYSDPVDVAFRYGEPPDSNLVAVPVAT
GIHRVLCASPGYLASHDMPQTPYDLSAHRCLCYMFGDDVHDRWRFAREDGETLTVRVKPANVSNDGDAVRRWALAGKGIA
YKAWFDVADDLAAGRLRALCTAWTAEASPLYMVVAGRSQLTPLLRGLRDFVAERVERLVARY
>Mature_302_residues
MRLLQELDIFVRTADNGSLSATARALDLTPAATSAALKRLEGELGVQLFVRSTRTMRLTREGEQYLAQCRPALEVLQQAS
RDLLTGNQAFQGVVRLSAPSDFGRNLLLPWLDAFQDRHPLVEFRLQLTDRMANIYSDPVDVAFRYGEPPDSNLVAVPVAT
GIHRVLCASPGYLASHDMPQTPYDLSAHRCLCYMFGDDVHDRWRFAREDGETLTVRVKPANVSNDGDAVRRWALAGKGIA
YKAWFDVADDLAAGRLRALCTAWTAEASPLYMVVAGRSQLTPLLRGLRDFVAERVERLVARY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=31.0580204778157, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87081978, Length=254, Percent_Identity=33.4645669291339, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789440, Length=280, Percent_Identity=30.7142857142857, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1789639, Length=300, Percent_Identity=28.6666666666667, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=25.6849315068493, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=29.4520547945205, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787589, Length=264, Percent_Identity=24.6212121212121, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789173, Length=260, Percent_Identity=28.8461538461538, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786448, Length=187, Percent_Identity=32.620320855615, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788706, Length=207, Percent_Identity=28.0193236714976, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI157672245, Length=178, Percent_Identity=28.0898876404494, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33665; Mature: 33665

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLQELDIFVRTADNGSLSATARALDLTPAATSAALKRLEGELGVQLFVRSTRTMRLTR
CCHHHHCCEEEEECCCCCCCHHHHEEECCCHHHHHHHHHHHHHHCCEEEEECCHHEEEHH
EGEQYLAQCRPALEVLQQASRDLLTGNQAFQGVVRLSAPSDFGRNLLLPWLDAFQDRHPL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEEECCCCCCCCCCHHHHHHHHCCCCCH
VEFRLQLTDRMANIYSDPVDVAFRYGEPPDSNLVAVPVATGIHRVLCASPGYLASHDMPQ
HHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCC
TPYDLSAHRCLCYMFGDDVHDRWRFAREDGETLTVRVKPANVSNDGDAVRRWALAGKGIA
CCCCCCHHHEEEEEECCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEE
YKAWFDVADDLAAGRLRALCTAWTAEASPLYMVVAGRSQLTPLLRGLRDFVAERVERLVA
EEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
RY
CC
>Mature Secondary Structure
MRLLQELDIFVRTADNGSLSATARALDLTPAATSAALKRLEGELGVQLFVRSTRTMRLTR
CCHHHHCCEEEEECCCCCCCHHHHEEECCCHHHHHHHHHHHHHHCCEEEEECCHHEEEHH
EGEQYLAQCRPALEVLQQASRDLLTGNQAFQGVVRLSAPSDFGRNLLLPWLDAFQDRHPL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEEECCCCCCCCCCHHHHHHHHCCCCCH
VEFRLQLTDRMANIYSDPVDVAFRYGEPPDSNLVAVPVATGIHRVLCASPGYLASHDMPQ
HHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCC
TPYDLSAHRCLCYMFGDDVHDRWRFAREDGETLTVRVKPANVSNDGDAVRRWALAGKGIA
CCCCCCHHHEEEEEECCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEE
YKAWFDVADDLAAGRLRALCTAWTAEASPLYMVVAGRSQLTPLLRGLRDFVAERVERLVA
EEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
RY
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]