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The map label for this gene is flhA [H]

Identifier: 94312631

GI number: 94312631

Start: 238552

End: 240639

Strand: Direct

Name: flhA [H]

Synonym: Rmet_3699

Alternate gene names: 94312631

Gene position: 238552-240639 (Clockwise)

Preceding gene: 94312630

Following gene: 94312632

Centisome position: 9.25

GC content: 65.76

Gene sequence:

>2088_bases
ATGAACGCACTGACGAACATCCTCAACATGCCGGGCCTGCGCTCTGGTGCCCAGATGAAGGCGCTCGCGGGGCCGGTGCT
GATCATCATGATCCTCGGCATGATGATCCTGCCGTTGCCCGCGTTTGTGCTGGACCTGCTGTTCACGTTCAACATTGCGC
TGTCGATCATGGTGCTGCTGGTCGGCATGTACACGCAGCGTCCGCTCGACTTCGCGGCGTTCCCGGCGGTCCTGCTGTTC
TCCACGCTGCTGCGCCTGTCGCTGAACGTTGCCTCCACGCGCGTGGTGCTGCTGGAAGGGCATACCGGCCCGGACGCCGC
CGGCAAGGTGATCGAAGCCTTCGGCCACTTCCTGGTGGGCGGCAACTTCGCGGTCGGTATCGTGGTGTTCGCGATCCTCG
TGGTGATCAACTTCATGGTGATCACCAAGGGCGCGGGCCGTATCGCCGAGGTGGGCGCGCGCTTCATGCTGGACGCGATG
CCGGGCAAGCAGATGGCGATCGACGCGGACCTGAACGCCGGCCTGATCAATGAAGAGGGCGCGCGCAAGCGTCGTGCCGA
GGTGGCGCAGGAGTCCGATTTCTACGGCGCGATGGATGGTGCGTCGAAGTTCGTGCGTGGCGATGCCATCGCGGGCCTGC
TGGTCATGTTCATCAACGTCGTGGCCGGCATGGTCGTGGGCATGGTGCAGCACGACCTGGACTTTGGCACGGCGGTGCAT
AACTACACGCTGCTGACGATTGGCGACGGCCTCGTGGCGCAGATTCCGGCACTGGTGATCTCCACGGCCGCCGGTGTCAT
CGTCTCGCGGGTGTCGAACGAGCAGGACGTCGGCCAGCAACTGACCGGCCAGCTCTTCTCGAATCCGCGCGTGTTGTTCA
TCACGGCCGCCATTATCGGCATGATGGGCATCATCCCGGGAATGCCGCATTTTGCGTTCTTGCTGCTGGCTGCCGGGCTG
ATCTGGCTTGGTCGGCACATGATGCGCCGCGAGGCCACGGCAGAAGAAACGAAGTCGAACGAGGCGCGCGCGCCTGCCGC
GCCGGCCGAGGCCGCCGAAGCGTCGTGGGAAGACGTCACGATGGTCGATCCGCTTGGCATGGAGGTGGGCTATCGCCTGA
TCACGCTGGTGGATCGCGCCCAGAACGGCGAGTTGCTGGGCCGCATCAAGAGCATCCGCAAGAAGATCGCGCAGGACATC
GGCTTTCTGGTTCCGGTGGTCCATATCCGCGACAACCTGGAACTGAAGCCGACCGCCTATCGCATCACGCTCAAGGGCGT
AGAGGTCGGCAGTGGCGAAGCCAACCCGGGCCAGTGGATGGCGATCAACCCGGGCCAGGTCACCGGCACGCTGCCCGGCG
CGGCCACGCGCGACCCGGCCTTTGGGCTGCCGGCCGTGTGGATCGACGCCGCCCTCAAGGAGCAGGCGCAGGCGTATGGC
TACACCGTGGTCGACGCCAGCACCGTGGTGGCCACCCACCTGAACCACCTGATCCAGATGCACGCATCCGAGCTGCTGGG
TCGCCAGGAAGTGCAGTCGCTGCTGGACCGCATCGCCAAGGAATCGCCCAAGCTTACCGAGGACCTGGTGCCGAAGACGA
TCACGCTGACTGGCCTGCAGAAGGTGCTGCAGAGCCTGCTGGACGAAGGTGTGGCGATCCGCGACATGCGCACGATTCTC
GATGTCATCGCCGAACACGCGCCGAAGGTCAGCGATCCGGCCGAGTTGACCACGCTCGTGCGCGTGGCGCTGGGCCGCGC
GATCACGCAGCAGCTTTTCCCCAACAACGCCGACCTGCAGGTCATCGGCCTCGACGCCGGCCTGGAGCGCGTGCTGTCGC
AGGCGCTGGCCAATGGCGGCGGCATTGAGCCGGGCCTGGCCGATGCGGTGCTGCAGCAGGCGCAGGGCGCGGTGGTGCGC
CAGGAGCAACTGGGTCTCGATCCGGTCCTGCTGGTGCCGTCGCCGCTGCGGCCGCTGATGGCGCGCTTCCTGCGCCGCAC
CCTGCCGCAGTTGAAAGTGCTGTCGCATGCCGAAGTACCGGACAACCGCAATATCCGCATCACCGCCATGATCGGCGGCG
CAGCGTAA

Upstream 100 bases:

>100_bases
TCTATCAACTGAAGAACTGGCACTACAGCTACGGTCCACAGCCCAATGGGCCCGCGGATCTGGTGGTGCCGGATGAACTT
GCCGTACCGGAAAGCCGCGC

Downstream 100 bases:

>100_bases
GGACTGAACATGAGCGTGGCAAAGTTTGTGGCGGCCAACGGCCGTGAAGCGATGCGCAAGGTGCGCGAGGCGATGGGCCC
GGATGCCGTGGTGCTGTCGA

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 695; Mature: 695

Protein sequence:

>695_residues
MNALTNILNMPGLRSGAQMKALAGPVLIIMILGMMILPLPAFVLDLLFTFNIALSIMVLLVGMYTQRPLDFAAFPAVLLF
STLLRLSLNVASTRVVLLEGHTGPDAAGKVIEAFGHFLVGGNFAVGIVVFAILVVINFMVITKGAGRIAEVGARFMLDAM
PGKQMAIDADLNAGLINEEGARKRRAEVAQESDFYGAMDGASKFVRGDAIAGLLVMFINVVAGMVVGMVQHDLDFGTAVH
NYTLLTIGDGLVAQIPALVISTAAGVIVSRVSNEQDVGQQLTGQLFSNPRVLFITAAIIGMMGIIPGMPHFAFLLLAAGL
IWLGRHMMRREATAEETKSNEARAPAAPAEAAEASWEDVTMVDPLGMEVGYRLITLVDRAQNGELLGRIKSIRKKIAQDI
GFLVPVVHIRDNLELKPTAYRITLKGVEVGSGEANPGQWMAINPGQVTGTLPGAATRDPAFGLPAVWIDAALKEQAQAYG
YTVVDASTVVATHLNHLIQMHASELLGRQEVQSLLDRIAKESPKLTEDLVPKTITLTGLQKVLQSLLDEGVAIRDMRTIL
DVIAEHAPKVSDPAELTTLVRVALGRAITQQLFPNNADLQVIGLDAGLERVLSQALANGGGIEPGLADAVLQQAQGAVVR
QEQLGLDPVLLVPSPLRPLMARFLRRTLPQLKVLSHAEVPDNRNIRITAMIGGAA

Sequences:

>Translated_695_residues
MNALTNILNMPGLRSGAQMKALAGPVLIIMILGMMILPLPAFVLDLLFTFNIALSIMVLLVGMYTQRPLDFAAFPAVLLF
STLLRLSLNVASTRVVLLEGHTGPDAAGKVIEAFGHFLVGGNFAVGIVVFAILVVINFMVITKGAGRIAEVGARFMLDAM
PGKQMAIDADLNAGLINEEGARKRRAEVAQESDFYGAMDGASKFVRGDAIAGLLVMFINVVAGMVVGMVQHDLDFGTAVH
NYTLLTIGDGLVAQIPALVISTAAGVIVSRVSNEQDVGQQLTGQLFSNPRVLFITAAIIGMMGIIPGMPHFAFLLLAAGL
IWLGRHMMRREATAEETKSNEARAPAAPAEAAEASWEDVTMVDPLGMEVGYRLITLVDRAQNGELLGRIKSIRKKIAQDI
GFLVPVVHIRDNLELKPTAYRITLKGVEVGSGEANPGQWMAINPGQVTGTLPGAATRDPAFGLPAVWIDAALKEQAQAYG
YTVVDASTVVATHLNHLIQMHASELLGRQEVQSLLDRIAKESPKLTEDLVPKTITLTGLQKVLQSLLDEGVAIRDMRTIL
DVIAEHAPKVSDPAELTTLVRVALGRAITQQLFPNNADLQVIGLDAGLERVLSQALANGGGIEPGLADAVLQQAQGAVVR
QEQLGLDPVLLVPSPLRPLMARFLRRTLPQLKVLSHAEVPDNRNIRITAMIGGAA
>Mature_695_residues
MNALTNILNMPGLRSGAQMKALAGPVLIIMILGMMILPLPAFVLDLLFTFNIALSIMVLLVGMYTQRPLDFAAFPAVLLF
STLLRLSLNVASTRVVLLEGHTGPDAAGKVIEAFGHFLVGGNFAVGIVVFAILVVINFMVITKGAGRIAEVGARFMLDAM
PGKQMAIDADLNAGLINEEGARKRRAEVAQESDFYGAMDGASKFVRGDAIAGLLVMFINVVAGMVVGMVQHDLDFGTAVH
NYTLLTIGDGLVAQIPALVISTAAGVIVSRVSNEQDVGQQLTGQLFSNPRVLFITAAIIGMMGIIPGMPHFAFLLLAAGL
IWLGRHMMRREATAEETKSNEARAPAAPAEAAEASWEDVTMVDPLGMEVGYRLITLVDRAQNGELLGRIKSIRKKIAQDI
GFLVPVVHIRDNLELKPTAYRITLKGVEVGSGEANPGQWMAINPGQVTGTLPGAATRDPAFGLPAVWIDAALKEQAQAYG
YTVVDASTVVATHLNHLIQMHASELLGRQEVQSLLDRIAKESPKLTEDLVPKTITLTGLQKVLQSLLDEGVAIRDMRTIL
DVIAEHAPKVSDPAELTTLVRVALGRAITQQLFPNNADLQVIGLDAGLERVLSQALANGGGIEPGLADAVLQQAQGAVVR
QEQLGLDPVLLVPSPLRPLMARFLRRTLPQLKVLSHAEVPDNRNIRITAMIGGAA

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=701, Percent_Identity=67.9029957203994, Blast_Score=932, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74194; Mature: 74194

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALTNILNMPGLRSGAQMKALAGPVLIIMILGMMILPLPAFVLDLLFTFNIALSIMVLL
CCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGMYTQRPLDFAAFPAVLLFSTLLRLSLNVASTRVVLLEGHTGPDAAGKVIEAFGHFLVG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCC
GNFAVGIVVFAILVVINFMVITKGAGRIAEVGARFMLDAMPGKQMAIDADLNAGLINEEG
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCH
ARKRRAEVAQESDFYGAMDGASKFVRGDAIAGLLVMFINVVAGMVVGMVQHDLDFGTAVH
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCHHHH
NYTLLTIGDGLVAQIPALVISTAAGVIVSRVSNEQDVGQQLTGQLFSNPRVLFITAAIIG
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEHHHHHHHH
MMGIIPGMPHFAFLLLAAGLIWLGRHMMRREATAEETKSNEARAPAAPAEAAEASWEDVT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCEE
MVDPLGMEVGYRLITLVDRAQNGELLGRIKSIRKKIAQDIGFLVPVVHIRDNLELKPTAY
EECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEE
RITLKGVEVGSGEANPGQWMAINPGQVTGTLPGAATRDPAFGLPAVWIDAALKEQAQAYG
EEEEEEEEECCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
YTVVDASTVVATHLNHLIQMHASELLGRQEVQSLLDRIAKESPKLTEDLVPKTITLTGLQ
EEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHCCCEEHHHHHH
KVLQSLLDEGVAIRDMRTILDVIAEHAPKVSDPAELTTLVRVALGRAITQQLFPNNADLQ
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VIGLDAGLERVLSQALANGGGIEPGLADAVLQQAQGAVVRQEQLGLDPVLLVPSPLRPLM
EEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCCEEECCCCHHHHH
ARFLRRTLPQLKVLSHAEVPDNRNIRITAMIGGAA
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MNALTNILNMPGLRSGAQMKALAGPVLIIMILGMMILPLPAFVLDLLFTFNIALSIMVLL
CCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGMYTQRPLDFAAFPAVLLFSTLLRLSLNVASTRVVLLEGHTGPDAAGKVIEAFGHFLVG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCC
GNFAVGIVVFAILVVINFMVITKGAGRIAEVGARFMLDAMPGKQMAIDADLNAGLINEEG
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCH
ARKRRAEVAQESDFYGAMDGASKFVRGDAIAGLLVMFINVVAGMVVGMVQHDLDFGTAVH
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCHHHH
NYTLLTIGDGLVAQIPALVISTAAGVIVSRVSNEQDVGQQLTGQLFSNPRVLFITAAIIG
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEHHHHHHHH
MMGIIPGMPHFAFLLLAAGLIWLGRHMMRREATAEETKSNEARAPAAPAEAAEASWEDVT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCEE
MVDPLGMEVGYRLITLVDRAQNGELLGRIKSIRKKIAQDIGFLVPVVHIRDNLELKPTAY
EECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEE
RITLKGVEVGSGEANPGQWMAINPGQVTGTLPGAATRDPAFGLPAVWIDAALKEQAQAYG
EEEEEEEEECCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
YTVVDASTVVATHLNHLIQMHASELLGRQEVQSLLDRIAKESPKLTEDLVPKTITLTGLQ
EEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHCCCEEHHHHHH
KVLQSLLDEGVAIRDMRTILDVIAEHAPKVSDPAELTTLVRVALGRAITQQLFPNNADLQ
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VIGLDAGLERVLSQALANGGGIEPGLADAVLQQAQGAVVRQEQLGLDPVLLVPSPLRPLM
EEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCCEEECCCCHHHHH
ARFLRRTLPQLKVLSHAEVPDNRNIRITAMIGGAA
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]