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The map label for this gene is ybdG [H]

Identifier: 94310759

GI number: 94310759

Start: 1976611

End: 1977954

Strand: Reverse

Name: ybdG [H]

Synonym: Rmet_1821

Alternate gene names: 94310759

Gene position: 1977954-1976611 (Counterclockwise)

Preceding gene: 94310760

Following gene: 94310754

Centisome position: 50.35

GC content: 64.29

Gene sequence:

>1344_bases
ATGACTTTCGACGCCCTGCTTGAACTGTTCGAGCAACGCATCCCGGCCCACCCGTGGGCACAGATCACCTTGTACGTCCT
GGCGCTGGTCCTGCTGGCCGGCATCGCGCAATGGCTCGTGGCGCGCGTGGTCGGCCGGGTGGTCTATCGCGTATTGAGTC
TTTCCGGCCACGGCAACTGGGCCGGGGCGCTGCTGCACCACCGGACCTATCGCCGGCTGGGCTACGCGGTATTCCTGGCC
GTGGTCACGGTCGGCATCAGCCAGGTGCCGAACCTGGGTAAGTTCTCGGCGGCCATCGAGCGGCTGGCTCATGCCGGCAC
CTGGATCAGCGTGTTCCTGATGCTGTCTGGCGTGCTCGATGCGTGGCAGACCGTGTTTTCCGGCAGCCGCAGCGCGCAGA
CGCATTCGATCAAGGGCTACATCCAGGTGGCCCAGCTCGCGCTGTGGCTGGTCTGCGGTGTGCTGGTGCTGTCGATCCTG
ATCGACCGCTCGCCGCTCTGGATGCTGTCCGGTATCGGCGCGCTATCTGCGGTGCTGCTGCTCGTGTTCAAGGACACGCT
GCTGTCCCTGGTGGCCAGCACGCAGCTCACCTCGAACGACATGCTGCGCATTGGCGACTGGATCGAAATGCCCCAGTCCA
ATGCCGATGGTTTCGTCATGGACGTGGCGCTGCATACGGTCAAGGTCAAGAATTGGGACAACACCGTGACGACGGTGCCA
ACCTACAAGCTGTTCTCGGAGAGCTACCGCAACTACCGGCACATGTTCGAGTCCGGCGCGCGCCGCATCAAACGGACGCT
CCGGATCGATGCCACCAGCGTGCGGTTCCTGGACGAGGAGGAGGTCAGGGCGCTGATGCGGTTCAAGCTGCTGCATGACT
ATCTCGAGGTCAAGCAGGAGGAGGTCGATCGGGCCAACCGGGAGATCCTGCGTGCCGACACAGACCCGGTCAACCGCCGT
CGGCTGACCAACCTGGGCACGTTCCGCGCCTATGGCATCGCCTTCCTGCGCGCGCATCCGGAAATTCATCACGATCTGCT
GCTGAACCTGCGGATGATGGAATCCGACTCGCAGGGCATTCCGATCGAGATTTACTGCTTTACCACGCTCACGAACTGGA
CGGACTACGAACGTATCCAGGGCGATATCTTCGACCACCTGTTCGCGATTCTGCCGGAGCTGGGTTTGCGGGTGTATCAG
GCGCCGTCAGGCGCGGACCTGAGCGGGCTGCGCAGCGGTGCGACGATGGCCGACCAGCACGCCGCACTGGCCGTGGCCGC
CGCGGACTCGGGGATGCGCCAGCCGCCATCGGCCCCGACGGATCGGGCCGACAGGGTGGCTTAG

Upstream 100 bases:

>100_bases
GCGCGTGCGTCGAGCGCGGCGGACGTCGAACGCCAAATGTGGGCGGGGCGGGCAGAAATAGTAGACTTGGCGATTGGCAG
CCCGTACCGCTTCACTGCAT

Downstream 100 bases:

>100_bases
GGGGGGATTTCTCCCTGTCCCTTCTCCCTTCTCCCTTCTCCCGTCGTCGGGAGAGGGGAGTCAGCAAAGCGCAGCGCTTA
CGCCTTCCGCGGCTTGACCT

Product: MscS-like transporter with mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTFDALLELFEQRIPAHPWAQITLYVLALVLLAGIAQWLVARVVGRVVYRVLSLSGHGNWAGALLHHRTYRRLGYAVFLA
VVTVGISQVPNLGKFSAAIERLAHAGTWISVFLMLSGVLDAWQTVFSGSRSAQTHSIKGYIQVAQLALWLVCGVLVLSIL
IDRSPLWMLSGIGALSAVLLLVFKDTLLSLVASTQLTSNDMLRIGDWIEMPQSNADGFVMDVALHTVKVKNWDNTVTTVP
TYKLFSESYRNYRHMFESGARRIKRTLRIDATSVRFLDEEEVRALMRFKLLHDYLEVKQEEVDRANREILRADTDPVNRR
RLTNLGTFRAYGIAFLRAHPEIHHDLLLNLRMMESDSQGIPIEIYCFTTLTNWTDYERIQGDIFDHLFAILPELGLRVYQ
APSGADLSGLRSGATMADQHAALAVAAADSGMRQPPSAPTDRADRVA

Sequences:

>Translated_447_residues
MTFDALLELFEQRIPAHPWAQITLYVLALVLLAGIAQWLVARVVGRVVYRVLSLSGHGNWAGALLHHRTYRRLGYAVFLA
VVTVGISQVPNLGKFSAAIERLAHAGTWISVFLMLSGVLDAWQTVFSGSRSAQTHSIKGYIQVAQLALWLVCGVLVLSIL
IDRSPLWMLSGIGALSAVLLLVFKDTLLSLVASTQLTSNDMLRIGDWIEMPQSNADGFVMDVALHTVKVKNWDNTVTTVP
TYKLFSESYRNYRHMFESGARRIKRTLRIDATSVRFLDEEEVRALMRFKLLHDYLEVKQEEVDRANREILRADTDPVNRR
RLTNLGTFRAYGIAFLRAHPEIHHDLLLNLRMMESDSQGIPIEIYCFTTLTNWTDYERIQGDIFDHLFAILPELGLRVYQ
APSGADLSGLRSGATMADQHAALAVAAADSGMRQPPSAPTDRADRVA
>Mature_446_residues
TFDALLELFEQRIPAHPWAQITLYVLALVLLAGIAQWLVARVVGRVVYRVLSLSGHGNWAGALLHHRTYRRLGYAVFLAV
VTVGISQVPNLGKFSAAIERLAHAGTWISVFLMLSGVLDAWQTVFSGSRSAQTHSIKGYIQVAQLALWLVCGVLVLSILI
DRSPLWMLSGIGALSAVLLLVFKDTLLSLVASTQLTSNDMLRIGDWIEMPQSNADGFVMDVALHTVKVKNWDNTVTTVPT
YKLFSESYRNYRHMFESGARRIKRTLRIDATSVRFLDEEEVRALMRFKLLHDYLEVKQEEVDRANREILRADTDPVNRRR
LTNLGTFRAYGIAFLRAHPEIHHDLLLNLRMMESDSQGIPIEIYCFTTLTNWTDYERIQGDIFDHLFAILPELGLRVYQA
PSGADLSGLRSGATMADQHAALAVAAADSGMRQPPSAPTDRADRVA

Specific function: Mechanosensitive channel of miniconductance that confers protection against mild hypoosmotic shock. Overexpression confers protection against severe shocks [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1786791, Length=355, Percent_Identity=44.2253521126761, Blast_Score=303, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 50056; Mature: 49924

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFDALLELFEQRIPAHPWAQITLYVLALVLLAGIAQWLVARVVGRVVYRVLSLSGHGNW
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
AGALLHHRTYRRLGYAVFLAVVTVGISQVPNLGKFSAAIERLAHAGTWISVFLMLSGVLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AWQTVFSGSRSAQTHSIKGYIQVAQLALWLVCGVLVLSILIDRSPLWMLSGIGALSAVLL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LVFKDTLLSLVASTQLTSNDMLRIGDWIEMPQSNADGFVMDVALHTVKVKNWDNTVTTVP
HHHHHHHHHHHHHHHCCCCCCEECCHHHHCCCCCCCCEEEEEHHHHEEEECCCCCEEECC
TYKLFSESYRNYRHMFESGARRIKRTLRIDATSVRFLDEEEVRALMRFKLLHDYLEVKQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCHHHHHHHHHHHHHHHHHHHHHH
EVDRANREILRADTDPVNRRRLTNLGTFRAYGIAFLRAHPEIHHDLLLNLRMMESDSQGI
HHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
PIEIYCFTTLTNWTDYERIQGDIFDHLFAILPELGLRVYQAPSGADLSGLRSGATMADQH
CEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHCCCCCHHHHH
AALAVAAADSGMRQPPSAPTDRADRVA
HHEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TFDALLELFEQRIPAHPWAQITLYVLALVLLAGIAQWLVARVVGRVVYRVLSLSGHGNW
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
AGALLHHRTYRRLGYAVFLAVVTVGISQVPNLGKFSAAIERLAHAGTWISVFLMLSGVLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AWQTVFSGSRSAQTHSIKGYIQVAQLALWLVCGVLVLSILIDRSPLWMLSGIGALSAVLL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LVFKDTLLSLVASTQLTSNDMLRIGDWIEMPQSNADGFVMDVALHTVKVKNWDNTVTTVP
HHHHHHHHHHHHHHHCCCCCCEECCHHHHCCCCCCCCEEEEEHHHHEEEECCCCCEEECC
TYKLFSESYRNYRHMFESGARRIKRTLRIDATSVRFLDEEEVRALMRFKLLHDYLEVKQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCHHHHHHHHHHHHHHHHHHHHHH
EVDRANREILRADTDPVNRRRLTNLGTFRAYGIAFLRAHPEIHHDLLLNLRMMESDSQGI
HHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
PIEIYCFTTLTNWTDYERIQGDIFDHLFAILPELGLRVYQAPSGADLSGLRSGATMADQH
CEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHCCCCCHHHHH
AALAVAAADSGMRQPPSAPTDRADRVA
HHEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 7813889 [H]