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The map label for this gene is clpX [H]

Identifier: 93007059

GI number: 93007059

Start: 2743118

End: 2744392

Strand: Direct

Name: clpX [H]

Synonym: Pcryo_2235

Alternate gene names: 93007059

Gene position: 2743118-2744392 (Clockwise)

Preceding gene: 93007058

Following gene: 93007060

Centisome position: 89.65

GC content: 43.84

Gene sequence:

>1275_bases
ATGGCAGAAGATAACACCCCGCAGTGCTCGTTTTGCGGCAAAGAAAAAAGTGAAGTGAAGCAGCTGATTGCCGCTGACGA
TGCCAATATCTGTAATGAATGTATTGAGCTATGTACAGACCTTATCGCCGACAGTGACGAACATGGTGATGACGATAGCG
ATATTGATACCTCTTGGGTCAATAAAAAACTGCCAACACCAAAAGAATTGCGCGCCAAGCTTGATGAATACGTCATCGGT
CAGGATGCTGCTAAGAAAGCCTTGGCTGTTGCCGTTTATAACCATTATAAGCGTCTAAAAGTTAGCCAAATTTTAGCCAA
TGATAGCAAAAAAGCTAAAATTGGTGCTGATGATGCAATGGTAGAATTGGCAAAGAGTAATATTTTGCTGATTGGTCCAA
CAGGTTCTGGTAAGACTTTACTTGCGCAAACGCTAGCACGTCTACTTGATGTTCCTTTTGCGATGGCGGATGCCACGACT
TTGACCGAAGCCGGTTATGTCGGTGAAGACGTTGAAAACATCGTACAAAAGCTATTACAAGCATCAGATTATGATGTTAG
TAAAGCGGAGCAAGGCATCATCTATATTGATGAGATTGATAAAATCAGCAAAAAAGGTGATAACCCTTCTATCACGCGTG
ATGTGTCGGGTGAAGGCGTACAGCAAGCATTGCTAAAACTTATCGAAGGTACGGTCGCGGCTATTCCGCCACACGGTGGT
CGTAAGCATCCGCAGCAAGAGTTGATCCAAGTAGATACCAGCAATATTTTGATTATCGTTGGTGGTGCGTTTGCCGGTCT
TGATAAAGTCATTCAGCAGCGTACTGAAAAGACAGGCATTGGCTTTAATGCTGATGTCAGCTCAAAAGATGATAGTCGTC
GTAGCTCAGAACTACTGCAACAAGTAGAGCCTGAAGATTTGATCAAGTTTGGACTTATTCCGGAGCTTATCGGTCGTCTT
CCAGTACTTGCTGCGCTTACAGAGCTAGACGAAGATGCATTGGTTCAGATTTTGACGGAACCTAAGAACGCCTTGGTTAA
GCAGTATAAGTATCTGTTTGATATGGAAGGCGCTGACATTACGTTTACCAAAGAAGCACTTGATGCGATTGCTAAAAAAG
CGATGGCACGCAAAACTGGTGCTCGTGGACTGCGCTCTATCGTTGAAAATGCTCTGTTAGAGACGATGTATGAGCTGCCT
TCTATGAAGGATGCTAAGACTGTACTCGTTGATGAGCAAGTGATTAACGAAGGCAAGACGCCTGAAATTGCTTAA

Upstream 100 bases:

>100_bases
TAGTAGCACTGCTTATGCTTAAGTGCTCTATATTAGGCACTTAAGCGTTGATACGCACATCAGAATATTTATAAGTATAA
AATTTTAGGAGTGCCTGTAT

Downstream 100 bases:

>100_bases
CTGTTAACCTGCTACATCACTCGTTTTAATTAGCGAAAAGTTAGTTAAAATTTAAAAAAAGCGCTCAAACATGATTTATG
TTTGAGCGCTTTTTTATGCT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MAEDNTPQCSFCGKEKSEVKQLIAADDANICNECIELCTDLIADSDEHGDDDSDIDTSWVNKKLPTPKELRAKLDEYVIG
QDAAKKALAVAVYNHYKRLKVSQILANDSKKAKIGADDAMVELAKSNILLIGPTGSGKTLLAQTLARLLDVPFAMADATT
LTEAGYVGEDVENIVQKLLQASDYDVSKAEQGIIYIDEIDKISKKGDNPSITRDVSGEGVQQALLKLIEGTVAAIPPHGG
RKHPQQELIQVDTSNILIIVGGAFAGLDKVIQQRTEKTGIGFNADVSSKDDSRRSSELLQQVEPEDLIKFGLIPELIGRL
PVLAALTELDEDALVQILTEPKNALVKQYKYLFDMEGADITFTKEALDAIAKKAMARKTGARGLRSIVENALLETMYELP
SMKDAKTVLVDEQVINEGKTPEIA

Sequences:

>Translated_424_residues
MAEDNTPQCSFCGKEKSEVKQLIAADDANICNECIELCTDLIADSDEHGDDDSDIDTSWVNKKLPTPKELRAKLDEYVIG
QDAAKKALAVAVYNHYKRLKVSQILANDSKKAKIGADDAMVELAKSNILLIGPTGSGKTLLAQTLARLLDVPFAMADATT
LTEAGYVGEDVENIVQKLLQASDYDVSKAEQGIIYIDEIDKISKKGDNPSITRDVSGEGVQQALLKLIEGTVAAIPPHGG
RKHPQQELIQVDTSNILIIVGGAFAGLDKVIQQRTEKTGIGFNADVSSKDDSRRSSELLQQVEPEDLIKFGLIPELIGRL
PVLAALTELDEDALVQILTEPKNALVKQYKYLFDMEGADITFTKEALDAIAKKAMARKTGARGLRSIVENALLETMYELP
SMKDAKTVLVDEQVINEGKTPEIA
>Mature_423_residues
AEDNTPQCSFCGKEKSEVKQLIAADDANICNECIELCTDLIADSDEHGDDDSDIDTSWVNKKLPTPKELRAKLDEYVIGQ
DAAKKALAVAVYNHYKRLKVSQILANDSKKAKIGADDAMVELAKSNILLIGPTGSGKTLLAQTLARLLDVPFAMADATTL
TEAGYVGEDVENIVQKLLQASDYDVSKAEQGIIYIDEIDKISKKGDNPSITRDVSGEGVQQALLKLIEGTVAAIPPHGGR
KHPQQELIQVDTSNILIIVGGAFAGLDKVIQQRTEKTGIGFNADVSSKDDSRRSSELLQQVEPEDLIKFGLIPELIGRLP
VLAALTELDEDALVQILTEPKNALVKQYKYLFDMEGADITFTKEALDAIAKKAMARKTGARGLRSIVENALLETMYELPS
MKDAKTVLVDEQVINEGKTPEIA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=432, Percent_Identity=44.6759259259259, Blast_Score=328, Evalue=6e-90,
Organism=Escherichia coli, GI1786642, Length=414, Percent_Identity=67.8743961352657, Blast_Score=556, Evalue=1e-160,
Organism=Escherichia coli, GI1790366, Length=117, Percent_Identity=39.3162393162393, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71982905, Length=305, Percent_Identity=48.1967213114754, Blast_Score=291, Evalue=6e-79,
Organism=Caenorhabditis elegans, GI71982908, Length=305, Percent_Identity=48.1967213114754, Blast_Score=290, Evalue=7e-79,
Organism=Caenorhabditis elegans, GI71988663, Length=403, Percent_Identity=38.7096774193548, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71988660, Length=250, Percent_Identity=39.2, Blast_Score=171, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=426, Percent_Identity=42.018779342723, Blast_Score=291, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24648291, Length=321, Percent_Identity=46.417445482866, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI24648289, Length=321, Percent_Identity=46.417445482866, Blast_Score=295, Evalue=5e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46079; Mature: 45948

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEDNTPQCSFCGKEKSEVKQLIAADDANICNECIELCTDLIADSDEHGDDDSDIDTSWV
CCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
NKKLPTPKELRAKLDEYVIGQDAAKKALAVAVYNHYKRLKVSQILANDSKKAKIGADDAM
HCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
VELAKSNILLIGPTGSGKTLLAQTLARLLDVPFAMADATTLTEAGYVGEDVENIVQKLLQ
HHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHH
ASDYDVSKAEQGIIYIDEIDKISKKGDNPSITRDVSGEGVQQALLKLIEGTVAAIPPHGG
CCCCCCHHHCCCEEEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCC
RKHPQQELIQVDTSNILIIVGGAFAGLDKVIQQRTEKTGIGFNADVSSKDDSRRSSELLQ
CCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
QVEPEDLIKFGLIPELIGRLPVLAALTELDEDALVQILTEPKNALVKQYKYLFDMEGADI
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCE
TFTKEALDAIAKKAMARKTGARGLRSIVENALLETMYELPSMKDAKTVLVDEQVINEGKT
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEECHHHHCCCCC
PEIA
CCCC
>Mature Secondary Structure 
AEDNTPQCSFCGKEKSEVKQLIAADDANICNECIELCTDLIADSDEHGDDDSDIDTSWV
CCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
NKKLPTPKELRAKLDEYVIGQDAAKKALAVAVYNHYKRLKVSQILANDSKKAKIGADDAM
HCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
VELAKSNILLIGPTGSGKTLLAQTLARLLDVPFAMADATTLTEAGYVGEDVENIVQKLLQ
HHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHH
ASDYDVSKAEQGIIYIDEIDKISKKGDNPSITRDVSGEGVQQALLKLIEGTVAAIPPHGG
CCCCCCHHHCCCEEEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCC
RKHPQQELIQVDTSNILIIVGGAFAGLDKVIQQRTEKTGIGFNADVSSKDDSRRSSELLQ
CCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
QVEPEDLIKFGLIPELIGRLPVLAALTELDEDALVQILTEPKNALVKQYKYLFDMEGADI
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCE
TFTKEALDAIAKKAMARKTGARGLRSIVENALLETMYELPSMKDAKTVLVDEQVINEGKT
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEECHHHHCCCCC
PEIA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA