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The map label for this gene is aroK [H]

Identifier: 93006992

GI number: 93006992

Start: 2660563

End: 2661123

Strand: Reverse

Name: aroK [H]

Synonym: Pcryo_2168

Alternate gene names: 93006992

Gene position: 2661123-2660563 (Counterclockwise)

Preceding gene: 93006993

Following gene: 93006991

Centisome position: 86.97

GC content: 47.59

Gene sequence:

>561_bases
ATGGTTGAGGAATTACCGTCGGTATTTTTGGTAGGGCCGATGGGAGCAGGGAAGACCACAATCGGCAGATTACTGGCAAA
GCAGCTCGGGCGCTCGTTTGTAGACAGCGATTGGTATATCGAATCGCAGACCGGTGCCGATATCGCTTGGATATTTGCCA
AAGAAGGTGAAGCGGGCTTTCGAGAACGGGAAACGCGTGCAATCGATGAGCTAACACAGCAACCGCAAATTGTTTTAGCG
ACTGGCGGCGGTGCTGTGATGGCAGCTGAAAATCGTGAGTATTTAAAGCAGCGCGGTATCGTTATTTATCTCAACGCGCC
TGTCGATGTACAAATGGCTCGTACTGCGAAAGACAAATCGCGTCCTTTATTACAGCAGCCAAACCCCAGAAAAATACTGC
AAGGTTTATATAGCGCGCGTGATCCATTGTACAGGGAAGTAGCGCATATTATTATGCCAACAGGACATACGTATCCACGG
CACATGGTCAATCAATTATTACAGCAGCTTAACTCATTTTGTATCTCTACGTCTGTCGATTCAGAGCCTGAAAAAGACTG
A

Upstream 100 bases:

>100_bases
TTTTTAGGCTGGCAAGGATTTTACTAACAATAATCACAGCTCATTACTAGCCAGAATATCAATGACGTTGTATCATACCT
AATTTAGCTGAGTGAGTACT

Downstream 100 bases:

>100_bases
TGTCAAAAAATGACTAGTATGACCAATATTATCGAATACCTATTTAGTTAAATTTTACTCGTAAGAATTAAGGAGATTTT
CATGGCAACGCCACTGTTTC

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MVEELPSVFLVGPMGAGKTTIGRLLAKQLGRSFVDSDWYIESQTGADIAWIFAKEGEAGFRERETRAIDELTQQPQIVLA
TGGGAVMAAENREYLKQRGIVIYLNAPVDVQMARTAKDKSRPLLQQPNPRKILQGLYSARDPLYREVAHIIMPTGHTYPR
HMVNQLLQQLNSFCISTSVDSEPEKD

Sequences:

>Translated_186_residues
MVEELPSVFLVGPMGAGKTTIGRLLAKQLGRSFVDSDWYIESQTGADIAWIFAKEGEAGFRERETRAIDELTQQPQIVLA
TGGGAVMAAENREYLKQRGIVIYLNAPVDVQMARTAKDKSRPLLQQPNPRKILQGLYSARDPLYREVAHIIMPTGHTYPR
HMVNQLLQQLNSFCISTSVDSEPEKD
>Mature_186_residues
MVEELPSVFLVGPMGAGKTTIGRLLAKQLGRSFVDSDWYIESQTGADIAWIFAKEGEAGFRERETRAIDELTQQPQIVLA
TGGGAVMAAENREYLKQRGIVIYLNAPVDVQMARTAKDKSRPLLQQPNPRKILQGLYSARDPLYREVAHIIMPTGHTYPR
HMVNQLLQQLNSFCISTSVDSEPEKD

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=170, Percent_Identity=50, Blast_Score=178, Evalue=2e-46,
Organism=Escherichia coli, GI1786587, Length=148, Percent_Identity=44.5945945945946, Blast_Score=124, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6320332, Length=152, Percent_Identity=30.9210526315789, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20771; Mature: 20771

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEELPSVFLVGPMGAGKTTIGRLLAKQLGRSFVDSDWYIESQTGADIAWIFAKEGEAGF
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCCCH
RERETRAIDELTQQPQIVLATGGGAVMAAENREYLKQRGIVIYLNAPVDVQMARTAKDKS
HHHHHHHHHHHHCCCEEEEEECCCEEEEECCHHHHHHCCEEEEEECCCCCHHHHHHCHHC
RPLLQQPNPRKILQGLYSARDPLYREVAHIIMPTGHTYPRHMVNQLLQQLNSFCISTSVD
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
SEPEKD
CCCCCC
>Mature Secondary Structure
MVEELPSVFLVGPMGAGKTTIGRLLAKQLGRSFVDSDWYIESQTGADIAWIFAKEGEAGF
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCCCH
RERETRAIDELTQQPQIVLATGGGAVMAAENREYLKQRGIVIYLNAPVDVQMARTAKDKS
HHHHHHHHHHHHCCCEEEEEECCCEEEEECCHHHHHHCCEEEEEECCCCCHHHHHHCHHC
RPLLQQPNPRKILQGLYSARDPLYREVAHIIMPTGHTYPRHMVNQLLQQLNSFCISTSVD
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
SEPEKD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA