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The map label for this gene is aroB [H]

Identifier: 93006991

GI number: 93006991

Start: 2659372

End: 2660481

Strand: Reverse

Name: aroB [H]

Synonym: Pcryo_2167

Alternate gene names: 93006991

Gene position: 2660481-2659372 (Counterclockwise)

Preceding gene: 93006992

Following gene: 93006990

Centisome position: 86.95

GC content: 46.49

Gene sequence:

>1110_bases
ATGGCAACGCCACTGTTTCATGCTGACTTGACAGTACATACGCAAAGTCATGACTATCCAATCGTCATTACTGAAAACGC
AATAGCAGAAAATAGCAGTATGGCTAGCCAAGTTGCCCCTTATATTACAGGTCGTCAAGTCCTTATCGTCACCAATGAAA
CGGTTGCGCCTTTATATTTAAAGGCTTTACAAGAGGAACTTGAAGCGCAGTTTACCGTGCAGGTGTGCGTGCTGCCAGAT
GGCGAACAATATAAGAACCAGTCGAGTATCAATCAGATTTATGATGTGTTGATGGCAGTGCATTTTAATCGTGATGTGAC
TTTGATTGCGCTTGGTGGTGGTGTCATTGGTGATATGACGGGATTTGCAGCAGCAAGCTTTATGCGCGGCGTCAATTTTA
TTCAGATACCAACCACCTTGCTGTCTCAAGTGGATTCAAGCGTCGGCGGCAAAACCGGTATCAATCATCCGCAAGGCAAA
AACATGATTGGCGCATTCTGGCAGCCGCAAATGGTATTGGCAGATATGAGTACACTCAAAACCCTGCCAGCGCGCGAGCT
GTCAGCAGGGCTTGCTGAAGTTATTAAATATGCGCTGATTATGGATGCCGAGTTCTTGACTTGGCTTGAGCACAATCTGC
CTGCGATGATGGCTTTGGATCTAGCGGTACTGGGTGAAGCGGTGAAGCGCTGCTGCCAGTACAAAGCTGATGTTGTCGCC
CAAGATGAAAGAGAATCAGGTGTACGCGCTTTATTAAATTTTGGTCATACGTTTGGTCATGTGATTGAAACTCATGAAGG
TTATGGTAGTTGGCTACATGGTGAGGCAGTTGCTGCGGGCATGGTACAAGCGGCTGAGCTGTCGCAAAAAATCGGCTGGT
TAACGAGCGATGAGGTTGCTTGTGTTAAGCGCATATTGTCATTAGCCAATTTACCGATCACGCCGCCGCCTATCGAAGTT
CAGACAGCTTTGGACTTAATGGGGCATGATAAAAAAGTGAAACACGGACAAATCCGCCTTATTTTGTTAAAATCATTGGG
TGAAGCAGTATTAACCAATGATTTTGACCCGCATCTGCTCACCGATGTGCTAGCCACGCATGCACCGTAA

Upstream 100 bases:

>100_bases
AGAGCCTGAAAAAGACTGATGTCAAAAAATGACTAGTATGACCAATATTATCGAATACCTATTTAGTTAAATTTTACTCG
TAAGAATTAAGGAGATTTTC

Downstream 100 bases:

>100_bases
GCTATAAAAGAACATACATTATAAATGGCTATGAGCAATTAATTGTTTTCAATATAGAAATAGCACGGTACTAAAAGCGA
TTCTCGTTTATTTTGAAGTG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MATPLFHADLTVHTQSHDYPIVITENAIAENSSMASQVAPYITGRQVLIVTNETVAPLYLKALQEELEAQFTVQVCVLPD
GEQYKNQSSINQIYDVLMAVHFNRDVTLIALGGGVIGDMTGFAAASFMRGVNFIQIPTTLLSQVDSSVGGKTGINHPQGK
NMIGAFWQPQMVLADMSTLKTLPARELSAGLAEVIKYALIMDAEFLTWLEHNLPAMMALDLAVLGEAVKRCCQYKADVVA
QDERESGVRALLNFGHTFGHVIETHEGYGSWLHGEAVAAGMVQAAELSQKIGWLTSDEVACVKRILSLANLPITPPPIEV
QTALDLMGHDKKVKHGQIRLILLKSLGEAVLTNDFDPHLLTDVLATHAP

Sequences:

>Translated_369_residues
MATPLFHADLTVHTQSHDYPIVITENAIAENSSMASQVAPYITGRQVLIVTNETVAPLYLKALQEELEAQFTVQVCVLPD
GEQYKNQSSINQIYDVLMAVHFNRDVTLIALGGGVIGDMTGFAAASFMRGVNFIQIPTTLLSQVDSSVGGKTGINHPQGK
NMIGAFWQPQMVLADMSTLKTLPARELSAGLAEVIKYALIMDAEFLTWLEHNLPAMMALDLAVLGEAVKRCCQYKADVVA
QDERESGVRALLNFGHTFGHVIETHEGYGSWLHGEAVAAGMVQAAELSQKIGWLTSDEVACVKRILSLANLPITPPPIEV
QTALDLMGHDKKVKHGQIRLILLKSLGEAVLTNDFDPHLLTDVLATHAP
>Mature_368_residues
ATPLFHADLTVHTQSHDYPIVITENAIAENSSMASQVAPYITGRQVLIVTNETVAPLYLKALQEELEAQFTVQVCVLPDG
EQYKNQSSINQIYDVLMAVHFNRDVTLIALGGGVIGDMTGFAAASFMRGVNFIQIPTTLLSQVDSSVGGKTGINHPQGKN
MIGAFWQPQMVLADMSTLKTLPARELSAGLAEVIKYALIMDAEFLTWLEHNLPAMMALDLAVLGEAVKRCCQYKADVVAQ
DERESGVRALLNFGHTFGHVIETHEGYGSWLHGEAVAAGMVQAAELSQKIGWLTSDEVACVKRILSLANLPITPPPIEVQ
TALDLMGHDKKVKHGQIRLILLKSLGEAVLTNDFDPHLLTDVLATHAP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=358, Percent_Identity=51.3966480446927, Blast_Score=348, Evalue=5e-97,
Organism=Saccharomyces cerevisiae, GI6320332, Length=318, Percent_Identity=39.937106918239, Blast_Score=212, Evalue=6e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40086; Mature: 39955

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPLFHADLTVHTQSHDYPIVITENAIAENSSMASQVAPYITGRQVLIVTNETVAPLYL
CCCCEEECCEEEEECCCCCCEEEECCCHHCCCHHHHHHHHHCCCCEEEEEECCCHHHHHH
KALQEELEAQFTVQVCVLPDGEQYKNQSSINQIYDVLMAVHFNRDVTLIALGGGVIGDMT
HHHHHHHCCEEEEEEEEECCCHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHH
GFAAASFMRGVNFIQIPTTLLSQVDSSVGGKTGINHPQGKNMIGAFWQPQMVLADMSTLK
HHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHH
TLPARELSAGLAEVIKYALIMDAEFLTWLEHNLPAMMALDLAVLGEAVKRCCQYKADVVA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
QDERESGVRALLNFGHTFGHVIETHEGYGSWLHGEAVAAGMVQAAELSQKIGWLTSDEVA
CCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
CVKRILSLANLPITPPPIEVQTALDLMGHDKKVKHGQIRLILLKSLGEAVLTNDFDPHLL
HHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEHHHHCHHHHCCCCCHHHH
TDVLATHAP
HHHHHHCCC
>Mature Secondary Structure 
ATPLFHADLTVHTQSHDYPIVITENAIAENSSMASQVAPYITGRQVLIVTNETVAPLYL
CCCEEECCEEEEECCCCCCEEEECCCHHCCCHHHHHHHHHCCCCEEEEEECCCHHHHHH
KALQEELEAQFTVQVCVLPDGEQYKNQSSINQIYDVLMAVHFNRDVTLIALGGGVIGDMT
HHHHHHHCCEEEEEEEEECCCHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHH
GFAAASFMRGVNFIQIPTTLLSQVDSSVGGKTGINHPQGKNMIGAFWQPQMVLADMSTLK
HHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHH
TLPARELSAGLAEVIKYALIMDAEFLTWLEHNLPAMMALDLAVLGEAVKRCCQYKADVVA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
QDERESGVRALLNFGHTFGHVIETHEGYGSWLHGEAVAAGMVQAAELSQKIGWLTSDEVA
CCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
CVKRILSLANLPITPPPIEVQTALDLMGHDKKVKHGQIRLILLKSLGEAVLTNDFDPHLL
HHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEHHHHCHHHHCCCCCHHHH
TDVLATHAP
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA