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The map label for this gene is ychM [C]

Identifier: 93006893

GI number: 93006893

Start: 2536150

End: 2537862

Strand: Direct

Name: ychM [C]

Synonym: Pcryo_2069

Alternate gene names: 93006893

Gene position: 2536150-2537862 (Clockwise)

Preceding gene: 93006892

Following gene: 93006894

Centisome position: 82.88

GC content: 47.46

Gene sequence:

>1713_bases
ATGCCCTCTATTGCCACTCGACTGATACCTGTTTGGTTACGTCAATATCAGCTGTCTGCCTTGCCAACCGATATCATTGC
AGGGATAGTCGTTGGTGTGCTCGTTATTCCGCAAAGCTTGGGCTATGCGGTCTTGGCAGGCTTGCCTCCGGTCTATGGCT
TATACGCGGCTATCGTGCCTGTGGCGGTATATGCGTGGCTCGGCTCTAGTAATGTACAAGCCGTCGGACCTGCTGCTGTG
ACCGCTATTATGACTGCAAGCGCGCTGCATCCTTATGCGGATAAGGGCGCTGAGCAGTATGTACTGATGGCAGCCCTACT
AGCACTCATGATGGGTGCGATTTTGTGGCTGGCAGGACAGCTGAAATTGGGCTGGATTATGCAGTTTATCAGCCGCGGCG
TCTCTGCTGGATTTATCAGTGGTGCCGCTGTGCTTATCTTTATAAGCCAGCTTAAATATCTAACTGGTATACCCATTTCA
GGCGATGGCTTAATCGGTTATTTATCGAGCATGCAGATGTATGCCAATCAGCTGCATCCGTTGACGCTAGTAATTGGTAT
CAGCGCCTTTGCACTCATGCTTCTTAATCGCTATGGTAAAAAATGGGTTTGGCAGTCTTGGTTATCCGCCTCTTATGCGA
AATGGGCAGAGCGCCTGTTTCCTCTTATACTGCTGACCGCTGCAATCGCTCTCAGTATCGTTTTACATTGGACGACAAGC
GGTGTGGCAACGATTGGTAATGTACCGAAAGGACTGCCAAGCTTTACAGCGCCATATCTGCCAGACTTTCATGAAGCGCT
CAATTTATTACCGACTGCAGGACTGATGGCGCTGATTGCGTTTGTATCGAGCAGCTCTGTTGCTAGCACTTATGCGCGTT
TGCGCGGTGAGCTATTTGATGCCAATCGCGAGCTGACAGGGCTTGGACTGGCTAATGTTGCCGGTAGCTTTTTTCAAAGC
TTTCCTATCGCTGGCGGATTTTCGCGTACGGCTATCAATGTCGATTCAGGTGCCAAAACGCCTTTAGCGAGCTTGGTCAC
AGTGTTAGTTATGATAGCTGCCTTGATAGCATTCGGGTATCTGCTTGCCCCGCTGCCCTATGCAATTTTGGGCGCAACCA
TCATGGCAGCTATCATAGGTCTTATTGACATAGCGACGCTAAAGTCGGCATGGCACCGCGACCGCTTAGATGCAGCAAGT
TTTATCGCCGCGTTTGTCGGCGTATTGATATTTGGGTTAAATACAGGGCTCGTGATTGGACTTATGGTGTCATTTGCTAG
CTTGATTTGGCAGTCAAGCAAACCGCATGTCGCTATCGTTGGGCAGCTAGCAGGGACAGGTCATTTTCGTAATATTAATC
GTCATGATGTAGTGACCTTTCACAATCTATTGATGCTGCGTATTGATGAGAGCTTGTTTTTTGGTAATAGCGAATCAGTG
CATCGTCACGTGGTACAAGCCACGCGTCAATATCCAGAGGCAAGCGAGATTATTCTTATTATGTCGGCCGTTAATCATAT
CGATTTGACCGGACAAGAGATGCTTATCAGCTTAAACCAAGAGCTATTAAATCAAAATAAGCATTTGAGCTTTAGCTTTA
TTAAAGGCCCTGTAATGGACATCATTGAGCACACACCGGTGATTACTGATTTATCGGGACACGTTTATTTAAGCACTATG
GATGCAGTTAATGGTTTAAAAGACACTCATTAA

Upstream 100 bases:

>100_bases
CAGCGTTTTTGTGCCCCTGCTGAGGCATAGATGATTGGCTAAATCTCATTGATTAAATTCTGATGTTCATGAACATTTTT
TATTGTGAGGACGTACTGCC

Downstream 100 bases:

>100_bases
TGTCATTTGTACTGTTTATTAGGCTAAGAATAATTAATGGCTATCTATAACATATAGATATGATAAAAGCTGTGTTATGC
TAAATTATTAGGACAACTAA

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 569

Protein sequence:

>570_residues
MPSIATRLIPVWLRQYQLSALPTDIIAGIVVGVLVIPQSLGYAVLAGLPPVYGLYAAIVPVAVYAWLGSSNVQAVGPAAV
TAIMTASALHPYADKGAEQYVLMAALLALMMGAILWLAGQLKLGWIMQFISRGVSAGFISGAAVLIFISQLKYLTGIPIS
GDGLIGYLSSMQMYANQLHPLTLVIGISAFALMLLNRYGKKWVWQSWLSASYAKWAERLFPLILLTAAIALSIVLHWTTS
GVATIGNVPKGLPSFTAPYLPDFHEALNLLPTAGLMALIAFVSSSSVASTYARLRGELFDANRELTGLGLANVAGSFFQS
FPIAGGFSRTAINVDSGAKTPLASLVTVLVMIAALIAFGYLLAPLPYAILGATIMAAIIGLIDIATLKSAWHRDRLDAAS
FIAAFVGVLIFGLNTGLVIGLMVSFASLIWQSSKPHVAIVGQLAGTGHFRNINRHDVVTFHNLLMLRIDESLFFGNSESV
HRHVVQATRQYPEASEIILIMSAVNHIDLTGQEMLISLNQELLNQNKHLSFSFIKGPVMDIIEHTPVITDLSGHVYLSTM
DAVNGLKDTH

Sequences:

>Translated_570_residues
MPSIATRLIPVWLRQYQLSALPTDIIAGIVVGVLVIPQSLGYAVLAGLPPVYGLYAAIVPVAVYAWLGSSNVQAVGPAAV
TAIMTASALHPYADKGAEQYVLMAALLALMMGAILWLAGQLKLGWIMQFISRGVSAGFISGAAVLIFISQLKYLTGIPIS
GDGLIGYLSSMQMYANQLHPLTLVIGISAFALMLLNRYGKKWVWQSWLSASYAKWAERLFPLILLTAAIALSIVLHWTTS
GVATIGNVPKGLPSFTAPYLPDFHEALNLLPTAGLMALIAFVSSSSVASTYARLRGELFDANRELTGLGLANVAGSFFQS
FPIAGGFSRTAINVDSGAKTPLASLVTVLVMIAALIAFGYLLAPLPYAILGATIMAAIIGLIDIATLKSAWHRDRLDAAS
FIAAFVGVLIFGLNTGLVIGLMVSFASLIWQSSKPHVAIVGQLAGTGHFRNINRHDVVTFHNLLMLRIDESLFFGNSESV
HRHVVQATRQYPEASEIILIMSAVNHIDLTGQEMLISLNQELLNQNKHLSFSFIKGPVMDIIEHTPVITDLSGHVYLSTM
DAVNGLKDTH
>Mature_569_residues
PSIATRLIPVWLRQYQLSALPTDIIAGIVVGVLVIPQSLGYAVLAGLPPVYGLYAAIVPVAVYAWLGSSNVQAVGPAAVT
AIMTASALHPYADKGAEQYVLMAALLALMMGAILWLAGQLKLGWIMQFISRGVSAGFISGAAVLIFISQLKYLTGIPISG
DGLIGYLSSMQMYANQLHPLTLVIGISAFALMLLNRYGKKWVWQSWLSASYAKWAERLFPLILLTAAIALSIVLHWTTSG
VATIGNVPKGLPSFTAPYLPDFHEALNLLPTAGLMALIAFVSSSSVASTYARLRGELFDANRELTGLGLANVAGSFFQSF
PIAGGFSRTAINVDSGAKTPLASLVTVLVMIAALIAFGYLLAPLPYAILGATIMAAIIGLIDIATLKSAWHRDRLDAASF
IAAFVGVLIFGLNTGLVIGLMVSFASLIWQSSKPHVAIVGQLAGTGHFRNINRHDVVTFHNLLMLRIDESLFFGNSESVH
RHVVQATRQYPEASEIILIMSAVNHIDLTGQEMLISLNQELLNQNKHLSFSFIKGPVMDIIEHTPVITDLSGHVYLSTMD
AVNGLKDTH

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=494, Percent_Identity=28.3400809716599, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI39752683, Length=494, Percent_Identity=28.3400809716599, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI4557535, Length=522, Percent_Identity=24.5210727969349, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI45827802, Length=454, Percent_Identity=29.0748898678414, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI269784651, Length=493, Percent_Identity=27.5862068965517, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI20336282, Length=513, Percent_Identity=24.1715399610136, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI16306483, Length=513, Percent_Identity=24.1715399610136, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI4505697, Length=527, Percent_Identity=24.6679316888046, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI16418457, Length=500, Percent_Identity=25, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI301601599, Length=500, Percent_Identity=25, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI47131207, Length=508, Percent_Identity=25.9842519685039, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI20336272, Length=508, Percent_Identity=25.9842519685039, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI16418413, Length=516, Percent_Identity=24.6124031007752, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI100913030, Length=526, Percent_Identity=22.8136882129278, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI217272867, Length=517, Percent_Identity=24.7582205029014, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI94721257, Length=239, Percent_Identity=25.9414225941423, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI94721259, Length=239, Percent_Identity=25.9414225941423, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI94721253, Length=239, Percent_Identity=25.9414225941423, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI94721255, Length=239, Percent_Identity=25.9414225941423, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI65506789, Length=435, Percent_Identity=28.2758620689655, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI301601602, Length=229, Percent_Identity=30.1310043668122, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI262206105, Length=300, Percent_Identity=26.6666666666667, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI262206075, Length=300, Percent_Identity=26.6666666666667, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI262206069, Length=300, Percent_Identity=26.6666666666667, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI262206063, Length=300, Percent_Identity=26.6666666666667, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI45827804, Length=205, Percent_Identity=32.1951219512195, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI87081859, Length=346, Percent_Identity=26.878612716763, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17551690, Length=554, Percent_Identity=26.5342960288809, Blast_Score=181, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI86564196, Length=518, Percent_Identity=26.8339768339768, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17566848, Length=572, Percent_Identity=26.048951048951, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI193203292, Length=522, Percent_Identity=26.4367816091954, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI86565215, Length=592, Percent_Identity=25.8445945945946, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI86564876, Length=566, Percent_Identity=23.8515901060071, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17562578, Length=613, Percent_Identity=25.4486133768352, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI86565213, Length=176, Percent_Identity=32.3863636363636, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71982567, Length=501, Percent_Identity=21.9560878243513, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI86565209, Length=248, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI86565211, Length=248, Percent_Identity=25.8064516129032, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319771, Length=469, Percent_Identity=25.1599147121535, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6323121, Length=471, Percent_Identity=27.1762208067941, Blast_Score=136, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6325260, Length=516, Percent_Identity=25, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI85815873, Length=543, Percent_Identity=30.5709023941068, Blast_Score=185, Evalue=8e-47,
Organism=Drosophila melanogaster, GI21355087, Length=572, Percent_Identity=27.0979020979021, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24647160, Length=571, Percent_Identity=26.6199649737303, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24649801, Length=563, Percent_Identity=28.0639431616341, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI19922482, Length=542, Percent_Identity=26.3837638376384, Blast_Score=178, Evalue=8e-45,
Organism=Drosophila melanogaster, GI21358229, Length=564, Percent_Identity=28.0141843971631, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24651449, Length=568, Percent_Identity=26.056338028169, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24663084, Length=591, Percent_Identity=28.2571912013536, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI21357695, Length=591, Percent_Identity=28.2571912013536, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI21358633, Length=553, Percent_Identity=26.2206148282098, Blast_Score=145, Evalue=9e-35,
Organism=Drosophila melanogaster, GI24666186, Length=674, Percent_Identity=23.2937685459941, Blast_Score=115, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 61074; Mature: 60942

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS50801 STAS ; PS01130 SLC26A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCEEECCCCEEEEEHHHHCCCCCCC
>Mature Secondary Structure 
PSIATRLIPVWLRQYQLSALPTDIIAGIVVGVLVIPQSLGYAVLAGLPPVYGLYAAIVP
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHH
VAVYAWLGSSNVQAVGPAAVTAIMTASALHPYADKGAEQYVLMAALLALMMGAILWLAGQ
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
LKLGWIMQFISRGVSAGFISGAAVLIFISQLKYLTGIPISGDGLIGYLSSMQMYANQLHP
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCH
LTLVIGISAFALMLLNRYGKKWVWQSWLSASYAKWAERLFPLILLTAAIALSIVLHWTTS
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVATIGNVPKGLPSFTAPYLPDFHEALNLLPTAGLMALIAFVSSSSVASTYARLRGELFD
CCHHHCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ANRELTGLGLANVAGSFFQSFPIAGGFSRTAINVDSGAKTPLASLVTVLVMIAALIAFGY
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
LLAPLPYAILGATIMAAIIGLIDIATLKSAWHRDRLDAASFIAAFVGVLIFGLNTGLVIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMVSFASLIWQSSKPHVAIVGQLAGTGHFRNINRHDVVTFHNLLMLRIDESLFFGNSESV
HHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHEECCHHCCCCCHHH
HRHVVQATRQYPEASEIILIMSAVNHIDLTGQEMLISLNQELLNQNKHLSFSFIKGPVMD
HHHHHHHHHHCCCHHHEEEHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEHHHCCHHHH
IIEHTPVITDLSGHVYLSTMDAVNGLKDTH
HHHCCCCEEECCCCEEEEEHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]