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The map label for this gene is gluP [H]

Identifier: 93006714

GI number: 93006714

Start: 2335822

End: 2336868

Strand: Direct

Name: gluP [H]

Synonym: Pcryo_1890

Alternate gene names: 93006714

Gene position: 2335822-2336868 (Clockwise)

Preceding gene: 93006713

Following gene: 93006715

Centisome position: 76.34

GC content: 41.55

Gene sequence:

>1047_bases
ATGACCATTCAACAATTATTAAAGACAGCGCCTGTTACCACCTTGTTATTAGTCAGCTTTATCGGGCTATTTATCATGCA
GGTATTAACGGGTGTCGATGCCAATAATCCTTCAACTGAAGCGCTGATAAAATGGGGTGCCAATGCCTTGCCTTTTACTA
TGGATAATGAGCCATGGCGCTTGGTGAGCAGTGCGTTTTTGCATATTGGGCTGATGCATTTATTGTTTAATGGTTTTGCC
ATGTATTTTTTTGGGCAAATCGCCGAGCCGATGTTTGGCTCCGCGAAGTTTTTGGCGCTATTTTTACTGGCAGCAATCGG
TGGCAACTTACTGAATAATTACGTCACATGGCAAGGTATTGTGGACGGGACAGGACAAGCCGGATTATCTGCGGGCGCAT
CGGGCGGTATCATGGGTATTGGCGCAGCGTTATTAATCGCCGCGCTGTTTAAGATATCAGTCAATGGTATGGTGCTGAAT
CTTAAAAGCCTGATATTTATTATGGGCATCAACCTAGTCTATGGTTTTGCGGTGCCGGGTATCGACAATGCTGGTCACAT
TGGCGGTGCGATTACCGGTCTTATCATTTCACTACCTTTTGCGATTGCCTATCGTCAACGTATGGCAGCTGTCATACAGA
ATATTGCCACTTACGAGAATGATTATTTACCCCATTATCAAAGTGAGCAACAAAACGAATATCATACCACTTATATTAAT
ACGCCAGTGAATAGCGGCACTGACTTTGATAATAATGCACACTTAAATAATACTCATTTAAATAACGCCAGTTTGCATAA
TGAGAGTCATGTAGATAATAATAGTGGTGTAAACTCAAACGTAACTGTTAACCCTACCAATCCTATTCGCCCTACTCTTA
ACGAAACTCTGAATGAAAAAAGCACAGCCATTAAACCTGCGCTTATTTGGCAATTGCTGCCATGGATTGTAATGTTATTT
ATTATCATTGGCTTTATGTGGTGGTGGCAAGATATTCATCAGCAATTAATAGAAGTGCTCAATGCCATTGAGCAAAGCAC
TGTTTAA

Upstream 100 bases:

>100_bases
AGTGTAGACGATATAACTACTTAGACTTGTTGGTCGCTTTCTTTATACTATCTATACCCTTTATACTGTACTGATAATTT
TTTATTGATAATTAGATGTT

Downstream 100 bases:

>100_bases
CCTATATCTCTTTTAGTTTTACCTGATTCCAATGTACAAAATCCTTACGAGTTTTACTATTTTTATCCCTTTGTTTCACC
CACTTATGAGAGCAAATCAT

Product: rhomboid-like protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MTIQQLLKTAPVTTLLLVSFIGLFIMQVLTGVDANNPSTEALIKWGANALPFTMDNEPWRLVSSAFLHIGLMHLLFNGFA
MYFFGQIAEPMFGSAKFLALFLLAAIGGNLLNNYVTWQGIVDGTGQAGLSAGASGGIMGIGAALLIAALFKISVNGMVLN
LKSLIFIMGINLVYGFAVPGIDNAGHIGGAITGLIISLPFAIAYRQRMAAVIQNIATYENDYLPHYQSEQQNEYHTTYIN
TPVNSGTDFDNNAHLNNTHLNNASLHNESHVDNNSGVNSNVTVNPTNPIRPTLNETLNEKSTAIKPALIWQLLPWIVMLF
IIIGFMWWWQDIHQQLIEVLNAIEQSTV

Sequences:

>Translated_348_residues
MTIQQLLKTAPVTTLLLVSFIGLFIMQVLTGVDANNPSTEALIKWGANALPFTMDNEPWRLVSSAFLHIGLMHLLFNGFA
MYFFGQIAEPMFGSAKFLALFLLAAIGGNLLNNYVTWQGIVDGTGQAGLSAGASGGIMGIGAALLIAALFKISVNGMVLN
LKSLIFIMGINLVYGFAVPGIDNAGHIGGAITGLIISLPFAIAYRQRMAAVIQNIATYENDYLPHYQSEQQNEYHTTYIN
TPVNSGTDFDNNAHLNNTHLNNASLHNESHVDNNSGVNSNVTVNPTNPIRPTLNETLNEKSTAIKPALIWQLLPWIVMLF
IIIGFMWWWQDIHQQLIEVLNAIEQSTV
>Mature_347_residues
TIQQLLKTAPVTTLLLVSFIGLFIMQVLTGVDANNPSTEALIKWGANALPFTMDNEPWRLVSSAFLHIGLMHLLFNGFAM
YFFGQIAEPMFGSAKFLALFLLAAIGGNLLNNYVTWQGIVDGTGQAGLSAGASGGIMGIGAALLIAALFKISVNGMVLNL
KSLIFIMGINLVYGFAVPGIDNAGHIGGAITGLIISLPFAIAYRQRMAAVIQNIATYENDYLPHYQSEQQNEYHTTYINT
PVNSGTDFDNNAHLNNTHLNNASLHNESHVDNNSGVNSNVTVNPTNPIRPTLNETLNEKSTAIKPALIWQLLPWIVMLFI
IIGFMWWWQDIHQQLIEVLNAIEQSTV

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 38028; Mature: 37897

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQQLLKTAPVTTLLLVSFIGLFIMQVLTGVDANNPSTEALIKWGANALPFTMDNEPWR
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCHHH
LVSSAFLHIGLMHLLFNGFAMYFFGQIAEPMFGSAKFLALFLLAAIGGNLLNNYVTWQGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEE
VDGTGQAGLSAGASGGIMGIGAALLIAALFKISVNGMVLNLKSLIFIMGINLVYGFAVPG
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHCCCC
IDNAGHIGGAITGLIISLPFAIAYRQRMAAVIQNIATYENDYLPHYQSEQQNEYHTTYIN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEE
TPVNSGTDFDNNAHLNNTHLNNASLHNESHVDNNSGVNSNVTVNPTNPIRPTLNETLNEK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHH
STAIKPALIWQLLPWIVMLFIIIGFMWWWQDIHQQLIEVLNAIEQSTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIQQLLKTAPVTTLLLVSFIGLFIMQVLTGVDANNPSTEALIKWGANALPFTMDNEPWR
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCHHH
LVSSAFLHIGLMHLLFNGFAMYFFGQIAEPMFGSAKFLALFLLAAIGGNLLNNYVTWQGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEE
VDGTGQAGLSAGASGGIMGIGAALLIAALFKISVNGMVLNLKSLIFIMGINLVYGFAVPG
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHCCCC
IDNAGHIGGAITGLIISLPFAIAYRQRMAAVIQNIATYENDYLPHYQSEQQNEYHTTYIN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEE
TPVNSGTDFDNNAHLNNTHLNNASLHNESHVDNNSGVNSNVTVNPTNPIRPTLNETLNEK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHH
STAIKPALIWQLLPWIVMLFIIIGFMWWWQDIHQQLIEVLNAIEQSTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]