Click here to switch to the map view.

The map label for this gene is trpS [H]

Identifier: 93006574

GI number: 93006574

Start: 2166016

End: 2167101

Strand: Direct

Name: trpS [H]

Synonym: Pcryo_1750

Alternate gene names: 93006574

Gene position: 2166016-2167101 (Clockwise)

Preceding gene: 93006573

Following gene: 93006575

Centisome position: 70.79

GC content: 44.75

Gene sequence:

>1086_bases
ATGAGTAATAATCAGATTTCTGACAGCCAACCTACTATTAATAGCTCAGCAGCCAAACGCATCCTTACTGGTATCAAACC
GACTGGCACCCTACATCTGGGTAATTACGTTGGCGCGATTCGTCCAGCGATTCAGTCTATCCAAAACAGTGACGACGAAG
CATTTTTCTTTTTAGCAGATTATCACGGTATTATTGGTTGTTATGACCCTGATATTATTCATGAATCGACCAAAGCCATT
GCAGCAACTTGGATTGCCTGCGGTCTTGACCCTGAGCGCGTGACTTTTTATCGTCAATCAGATGTGCCTGAAATCCCAGA
ACTTGCGTGGATATTGAACTGCTCATGTGCAAAAGGTCTCATGAATCGTGCGCACGCTTATAAAGCGTCAGTCGATATTA
ATATGGAAAAGGAAGATGTTGATCCCGATCAAGGTATTAACATGGGGCTGTTCGGCTATCCGGTACTGATGGCAGCCGAT
ATCTTAATGTTCAATGCTACGCATGTGCCTGTTGGTCGTGATCAAATTCAGCATATCGAGATGGCTCGTGATATTGCTGG
TACTTTTAATCATCGCTATAAGCCACTGTTTACGCTACCATCTGCTGTTGTAGATGACGATATCCCACTACTCACAGGTC
TTGATGGTCGTAAGATGAGTAAGAGCTATAGCAATACCATTCCCCTATTTGGTGATCTAAATCCACAAGTTAGTGCTGAA
AAGCAGATGCATAAAGCCATCATGAAGATCGTCACCAACTCGCAGTTGCCTGCTGAGCCAAAAGACCCTGATGACTCTGC
TATTTTCGAGATTTATAAAGCCTTTGCAACGCCTACTGAGATTGCCGATATGCGTGCGCAGTTTGCCGCTGGTATTGGCT
GGGGCGATGCCAAACAAGCGTTGTTTGATAAAATCAATGATGAAGTTGCCCCATTCCGCGCACGTTATGAGGAACTGATG
GCAAATCCAAAAGAGCTAGAAGAAATCCTACAGATGGGTGCAGAAAAAGCCCGCCGTCATAGTCGTAAGCAACTAGATAA
GACCCGCCGCGCTATTGGTATCCGTCCACTTGCCAAACTTAAATAA

Upstream 100 bases:

>100_bases
GCAAAATTTGCTATAATTTACAGCTAATATTTTTTGCTATTATCAGCAGATAAATAATCATGAATTTATAATAATTTGAT
CAATAAATAACGGATTTCCC

Downstream 100 bases:

>100_bases
ATTATTATTTACGATGACCATAGATTGCTATCATGCAAAGTAAGCGATTAATTGAGTCTAGCGCAGAGATTCATGATATG
TCTCTGCGTATCTATCAGAC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MSNNQISDSQPTINSSAAKRILTGIKPTGTLHLGNYVGAIRPAIQSIQNSDDEAFFFLADYHGIIGCYDPDIIHESTKAI
AATWIACGLDPERVTFYRQSDVPEIPELAWILNCSCAKGLMNRAHAYKASVDINMEKEDVDPDQGINMGLFGYPVLMAAD
ILMFNATHVPVGRDQIQHIEMARDIAGTFNHRYKPLFTLPSAVVDDDIPLLTGLDGRKMSKSYSNTIPLFGDLNPQVSAE
KQMHKAIMKIVTNSQLPAEPKDPDDSAIFEIYKAFATPTEIADMRAQFAAGIGWGDAKQALFDKINDEVAPFRARYEELM
ANPKELEEILQMGAEKARRHSRKQLDKTRRAIGIRPLAKLK

Sequences:

>Translated_361_residues
MSNNQISDSQPTINSSAAKRILTGIKPTGTLHLGNYVGAIRPAIQSIQNSDDEAFFFLADYHGIIGCYDPDIIHESTKAI
AATWIACGLDPERVTFYRQSDVPEIPELAWILNCSCAKGLMNRAHAYKASVDINMEKEDVDPDQGINMGLFGYPVLMAAD
ILMFNATHVPVGRDQIQHIEMARDIAGTFNHRYKPLFTLPSAVVDDDIPLLTGLDGRKMSKSYSNTIPLFGDLNPQVSAE
KQMHKAIMKIVTNSQLPAEPKDPDDSAIFEIYKAFATPTEIADMRAQFAAGIGWGDAKQALFDKINDEVAPFRARYEELM
ANPKELEEILQMGAEKARRHSRKQLDKTRRAIGIRPLAKLK
>Mature_360_residues
SNNQISDSQPTINSSAAKRILTGIKPTGTLHLGNYVGAIRPAIQSIQNSDDEAFFFLADYHGIIGCYDPDIIHESTKAIA
ATWIACGLDPERVTFYRQSDVPEIPELAWILNCSCAKGLMNRAHAYKASVDINMEKEDVDPDQGINMGLFGYPVLMAADI
LMFNATHVPVGRDQIQHIEMARDIAGTFNHRYKPLFTLPSAVVDDDIPLLTGLDGRKMSKSYSNTIPLFGDLNPQVSAEK
QMHKAIMKIVTNSQLPAEPKDPDDSAIFEIYKAFATPTEIADMRAQFAAGIGWGDAKQALFDKINDEVAPFRARYEELMA
NPKELEEILQMGAEKARRHSRKQLDKTRRAIGIRPLAKLK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=348, Percent_Identity=29.8850574712644, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI41352700, Length=199, Percent_Identity=37.6884422110553, Blast_Score=159, Evalue=4e-39,
Organism=Escherichia coli, GI1789786, Length=342, Percent_Identity=33.0409356725146, Blast_Score=167, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71982800, Length=342, Percent_Identity=32.1637426900585, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI71982793, Length=357, Percent_Identity=31.6526610644258, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6320474, Length=345, Percent_Identity=30.4347826086957, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24666151, Length=360, Percent_Identity=32.5, Blast_Score=172, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 40091; Mature: 39960

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNQISDSQPTINSSAAKRILTGIKPTGTLHLGNYVGAIRPAIQSIQNSDDEAFFFLAD
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHCCCCCEEEEEEE
YHGIIGCYDPDIIHESTKAIAATWIACGLDPERVTFYRQSDVPEIPELAWILNCSCAKGL
CCCEEECCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCHHHHHHCCHHHHHH
MNRAHAYKASVDINMEKEDVDPDQGINMGLFGYPVLMAADILMFNATHVPVGRDQIQHIE
HHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
MARDIAGTFNHRYKPLFTLPSAVVDDDIPLLTGLDGRKMSKSYSNTIPLFGDLNPQVSAE
HHHHHHHHHCCCCCCCEECCHHHHCCCCCEEECCCCHHHHHHHCCCCCCEECCCCCCHHH
KQMHKAIMKIVTNSQLPAEPKDPDDSAIFEIYKAFATPTEIADMRAQFAAGIGWGDAKQA
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHH
LFDKINDEVAPFRARYEELMANPKELEEILQMGAEKARRHSRKQLDKTRRAIGIRPLAKL
HHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
K
C
>Mature Secondary Structure 
SNNQISDSQPTINSSAAKRILTGIKPTGTLHLGNYVGAIRPAIQSIQNSDDEAFFFLAD
CCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHCCCCCEEEEEEE
YHGIIGCYDPDIIHESTKAIAATWIACGLDPERVTFYRQSDVPEIPELAWILNCSCAKGL
CCCEEECCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCHHHHHHCCHHHHHH
MNRAHAYKASVDINMEKEDVDPDQGINMGLFGYPVLMAADILMFNATHVPVGRDQIQHIE
HHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
MARDIAGTFNHRYKPLFTLPSAVVDDDIPLLTGLDGRKMSKSYSNTIPLFGDLNPQVSAE
HHHHHHHHHCCCCCCCEECCHHHHCCCCCEEECCCCHHHHHHHCCCCCCEECCCCCCHHH
KQMHKAIMKIVTNSQLPAEPKDPDDSAIFEIYKAFATPTEIADMRAQFAAGIGWGDAKQA
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHH
LFDKINDEVAPFRARYEELMANPKELEEILQMGAEKARRHSRKQLDKTRRAIGIRPLAKL
HHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]