Click here to switch to the map view.

The map label for this gene is lpxP [H]

Identifier: 93006573

GI number: 93006573

Start: 2164799

End: 2165890

Strand: Direct

Name: lpxP [H]

Synonym: Pcryo_1749

Alternate gene names: 93006573

Gene position: 2164799-2165890 (Clockwise)

Preceding gene: 93006572

Following gene: 93006574

Centisome position: 70.75

GC content: 46.43

Gene sequence:

>1092_bases
ATGAAAGCGCCTGAACAATACGATCCTAGCAAATCTGCCTCAAAGAGCAGCATGCCGCCACCAAGTATACAGCCGCCTGC
TAAGTCTCCGGCTCTACCTGTTGGCACACCGACGATTACCCAAACGCATAAGCAGACCGATCAAGCAGAAAAGAAACCTT
TTGAATGGCAGTTTTTAATGCCTAAATATTGGGGTATTTGGCTATTATTTGCTATTTTTTTGCCGCTGATTTATCTACCG
CTACGGTGGCAATTTTGGCTCGGTCGCAAGCTTGGTATTTTGATCTATAGTGTCGTAGGCTCACGCCGCCGTGATACCTT
AATTAACCTCAAACTGGCATTTCCAGAAAAGCCAGAAGTGGAACGTGAGCTCATGGCAAAACAAGTCTTTGTCAATCAGG
GCATTGGCGTATTTGAAACCTTATGCGCTTGGTTCCGCCCGAATGTTTTTACCCGCACTGTGTCTATCTCAGGGTTACAG
CATCTTGTGAATGCACAAAATGAGGGTCGCGCGGTCATCTTATTGGGTGCCCATTATACGATGCTTGATCTAGGCGGTAT
GCTCTGTACCCAGTTCTTCCCAATGGATGGTATGTATCGTCCGCAAAATAACGCATTGCTTGATTGGTTCATTTATAATG
GGCGCACAAGTATTCTGAGTAAACAAATCTCCAACCGTGATATGCGTAGCCTCGTTGGCTCTCTTAAAAAGGGTCGTGTG
ATTTGGTATTCACCGGATCAAGATTATGGTCTAAAACAAGGGGTCATGGCGCCATTTTTTGGTGTACCAGCAGCAACTCT
GACGGCAACGCGGCGATTGGCAACCTTAGGCAATAAAGTGCATCCACCAGCCGTAATGGCGCTGCATACTTATCGACAGA
CGCCAGATAATTTGCCAAGTGGCAAACGCCCCCATTATCATCTGACGATTACGCCAGAGCTGGAGAACTATCCAAGTGAT
AACGAAGTGGCTGACGCGACTCGCGTTAATGAAGTACTAGAGGGCTTGATTCGTATTGATCCCACTCAGTGGATGTGGTT
CCATCGCCGTTTTAAAAATGTTCCCGAAGGTCGTAGAGATATCTATAAGTAA

Upstream 100 bases:

>100_bases
TCTTGCCTATAAATCTGTCTTAACAAAGTATAAATCACCTTGCAAAGTCTCGCTTACTACCCCATCATAATCATAACTTT
TCATTACTAGTAACAGTCTT

Downstream 100 bases:

>100_bases
GCTTTTATTCCGACGAAAATCACTGGCAAAATTTGCTATAATTTACAGCTAATATTTTTTGCTATTATCAGCAGATAAAT
AATCATGAATTTATAATAAT

Product: lipid A biosynthesis acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MKAPEQYDPSKSASKSSMPPPSIQPPAKSPALPVGTPTITQTHKQTDQAEKKPFEWQFLMPKYWGIWLLFAIFLPLIYLP
LRWQFWLGRKLGILIYSVVGSRRRDTLINLKLAFPEKPEVERELMAKQVFVNQGIGVFETLCAWFRPNVFTRTVSISGLQ
HLVNAQNEGRAVILLGAHYTMLDLGGMLCTQFFPMDGMYRPQNNALLDWFIYNGRTSILSKQISNRDMRSLVGSLKKGRV
IWYSPDQDYGLKQGVMAPFFGVPAATLTATRRLATLGNKVHPPAVMALHTYRQTPDNLPSGKRPHYHLTITPELENYPSD
NEVADATRVNEVLEGLIRIDPTQWMWFHRRFKNVPEGRRDIYK

Sequences:

>Translated_363_residues
MKAPEQYDPSKSASKSSMPPPSIQPPAKSPALPVGTPTITQTHKQTDQAEKKPFEWQFLMPKYWGIWLLFAIFLPLIYLP
LRWQFWLGRKLGILIYSVVGSRRRDTLINLKLAFPEKPEVERELMAKQVFVNQGIGVFETLCAWFRPNVFTRTVSISGLQ
HLVNAQNEGRAVILLGAHYTMLDLGGMLCTQFFPMDGMYRPQNNALLDWFIYNGRTSILSKQISNRDMRSLVGSLKKGRV
IWYSPDQDYGLKQGVMAPFFGVPAATLTATRRLATLGNKVHPPAVMALHTYRQTPDNLPSGKRPHYHLTITPELENYPSD
NEVADATRVNEVLEGLIRIDPTQWMWFHRRFKNVPEGRRDIYK
>Mature_363_residues
MKAPEQYDPSKSASKSSMPPPSIQPPAKSPALPVGTPTITQTHKQTDQAEKKPFEWQFLMPKYWGIWLLFAIFLPLIYLP
LRWQFWLGRKLGILIYSVVGSRRRDTLINLKLAFPEKPEVERELMAKQVFVNQGIGVFETLCAWFRPNVFTRTVSISGLQ
HLVNAQNEGRAVILLGAHYTMLDLGGMLCTQFFPMDGMYRPQNNALLDWFIYNGRTSILSKQISNRDMRSLVGSLKKGRV
IWYSPDQDYGLKQGVMAPFFGVPAATLTATRRLATLGNKVHPPAVMALHTYRQTPDNLPSGKRPHYHLTITPELENYPSD
NEVADATRVNEVLEGLIRIDPTQWMWFHRRFKNVPEGRRDIYK

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=311, Percent_Identity=36.3344051446945, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787292, Length=306, Percent_Identity=35.2941176470588, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1788161, Length=320, Percent_Identity=26.875, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 41557; Mature: 41557

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAPEQYDPSKSASKSSMPPPSIQPPAKSPALPVGTPTITQTHKQTDQAEKKPFEWQFLM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEC
PKYWGIWLLFAIFLPLIYLPLRWQFWLGRKLGILIYSVVGSRRRDTLINLKLAFPEKPEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCH
ERELMAKQVFVNQGIGVFETLCAWFRPNVFTRTVSISGLQHLVNAQNEGRAVILLGAHYT
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHCCCCCCCEEEEECCCHH
MLDLGGMLCTQFFPMDGMYRPQNNALLDWFIYNGRTSILSKQISNRDMRSLVGSLKKGRV
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHCCEE
IWYSPDQDYGLKQGVMAPFFGVPAATLTATRRLATLGNKVHPPAVMALHTYRQTPDNLPS
EEECCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
GKRPHYHLTITPELENYPSDNEVADATRVNEVLEGLIRIDPTQWMWFHRRFKNVPEGRRD
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHH
IYK
HCC
>Mature Secondary Structure
MKAPEQYDPSKSASKSSMPPPSIQPPAKSPALPVGTPTITQTHKQTDQAEKKPFEWQFLM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEC
PKYWGIWLLFAIFLPLIYLPLRWQFWLGRKLGILIYSVVGSRRRDTLINLKLAFPEKPEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCH
ERELMAKQVFVNQGIGVFETLCAWFRPNVFTRTVSISGLQHLVNAQNEGRAVILLGAHYT
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHCCCCCCCEEEEECCCHH
MLDLGGMLCTQFFPMDGMYRPQNNALLDWFIYNGRTSILSKQISNRDMRSLVGSLKKGRV
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHCCEE
IWYSPDQDYGLKQGVMAPFFGVPAATLTATRRLATLGNKVHPPAVMALHTYRQTPDNLPS
EEECCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
GKRPHYHLTITPELENYPSDNEVADATRVNEVLEGLIRIDPTQWMWFHRRFKNVPEGRRD
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHH
IYK
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]