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The map label for this gene is dinB [H]

Identifier: 93006387

GI number: 93006387

Start: 1916898

End: 1918013

Strand: Direct

Name: dinB [H]

Synonym: Pcryo_1563

Alternate gene names: 93006387

Gene position: 1916898-1918013 (Clockwise)

Preceding gene: 93006385

Following gene: 93006388

Centisome position: 62.65

GC content: 45.16

Gene sequence:

>1116_bases
ATGACAATACATGTTACAACAACAAACACTAAACCTGCCGTTAGCCAATCTAACCTTCGCAAAATCATTCATATCGATAT
GGATGCTTTTTATGCCAGTGTAGAACAGCGTGATTTTCCTGAGCTGCGTGGCAAGCCATTGGTGGTTGGCGGCGATCCCA
ATGGTCGCGGTGTGGTTGCGGCAGCAAGCTATGAAGTTCGTAAGTTTGGCGTACGCTCCGCGATGTCATGCTATGAAGCC
AGAAAGCGCTGTCCTGAGGTGATATTTGTACCGCCGCGCTTTGATGTTTACCGTGCTGTTAGTGTTGAGATACGTCGTAT
CATGCACATTCTGACCCCACATGTTGAGCCGTTATCATTAGACGAAGCCTATTTGGATGTTACTGGATTGTCTGTTCATC
AAGGCTCAGCCACATTAATGGCAAATTGGTTACGAGCGCAGATTTTAGGACAAACGGGTCTAAACGCCTCTGCCGGTGTC
TCATTTAATAAAATGCTGGCGAAAATTGCCTCTGATATTAATAAACCTAATGGCACAGCGGTCATCACGCCAGCGGATGC
TGATGCCTTTATCAGCGCTTTGCCTATTGAACGCTTCCACGGTATTGGTAAAGCAACGGCCAAACGCCTGCATGCAATGG
GTGTTAGTAACGGCGCTGACCTTCGGCGTACGCCAGCTGCCATACTAGTCAATGAGTTCGGTAAGCGTGGACAGTTTTAT
CATGATATCGCTCATGGACGTGATGAGCGTGCGGTCAAGTCTGAGCGTACACACAAATCAGTGGGCTCTGAGACTACGTT
TAGAGAAAACTTAACGGATGATAATGAACTAAAAATACAAATCTATGAACAAAATGCTGATGCCTTTAGTCAGCTGCACA
AAAAACAGCTTATTGCCTATACTATTACTCTAAAGGTCAAATACTCAGATTTTACTCAAGTCACGCGCTCGCATACCTTA
TCGACGGCATTTGATAGCGCAGAATCCGCTCACTTTTGGTTAGATAAGCTATTTTTGGACATTCCGCGTACTCTTCCTAT
TCGATTGGTTGGTGTGACATTTTCTTCGCTCACATCTGCAACGCAAGTCACGCCACAATTAAATTTATTTGAATGA

Upstream 100 bases:

>100_bases
AATGAAACTCTTGTTTTTTATTAACCTATGTAACACTTCTCACTTTTTGAGTGAGCATTAGAGACCAAAATCGGTGCGAA
AAATCAGGTAAAATAGTTTT

Downstream 100 bases:

>100_bases
TTTTTCGCCTGAATTTTTTAGAGAGTTTTCCTAAATAAATATCTCAATTTTTTACTTAGGCTATTTTATTTATATTTAGA
GGTAAATAAAAAAGTACCAC

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MTIHVTTTNTKPAVSQSNLRKIIHIDMDAFYASVEQRDFPELRGKPLVVGGDPNGRGVVAAASYEVRKFGVRSAMSCYEA
RKRCPEVIFVPPRFDVYRAVSVEIRRIMHILTPHVEPLSLDEAYLDVTGLSVHQGSATLMANWLRAQILGQTGLNASAGV
SFNKMLAKIASDINKPNGTAVITPADADAFISALPIERFHGIGKATAKRLHAMGVSNGADLRRTPAAILVNEFGKRGQFY
HDIAHGRDERAVKSERTHKSVGSETTFRENLTDDNELKIQIYEQNADAFSQLHKKQLIAYTITLKVKYSDFTQVTRSHTL
STAFDSAESAHFWLDKLFLDIPRTLPIRLVGVTFSSLTSATQVTPQLNLFE

Sequences:

>Translated_371_residues
MTIHVTTTNTKPAVSQSNLRKIIHIDMDAFYASVEQRDFPELRGKPLVVGGDPNGRGVVAAASYEVRKFGVRSAMSCYEA
RKRCPEVIFVPPRFDVYRAVSVEIRRIMHILTPHVEPLSLDEAYLDVTGLSVHQGSATLMANWLRAQILGQTGLNASAGV
SFNKMLAKIASDINKPNGTAVITPADADAFISALPIERFHGIGKATAKRLHAMGVSNGADLRRTPAAILVNEFGKRGQFY
HDIAHGRDERAVKSERTHKSVGSETTFRENLTDDNELKIQIYEQNADAFSQLHKKQLIAYTITLKVKYSDFTQVTRSHTL
STAFDSAESAHFWLDKLFLDIPRTLPIRLVGVTFSSLTSATQVTPQLNLFE
>Mature_370_residues
TIHVTTTNTKPAVSQSNLRKIIHIDMDAFYASVEQRDFPELRGKPLVVGGDPNGRGVVAAASYEVRKFGVRSAMSCYEAR
KRCPEVIFVPPRFDVYRAVSVEIRRIMHILTPHVEPLSLDEAYLDVTGLSVHQGSATLMANWLRAQILGQTGLNASAGVS
FNKMLAKIASDINKPNGTAVITPADADAFISALPIERFHGIGKATAKRLHAMGVSNGADLRRTPAAILVNEFGKRGQFYH
DIAHGRDERAVKSERTHKSVGSETTFRENLTDDNELKIQIYEQNADAFSQLHKKQLIAYTITLKVKYSDFTQVTRSHTLS
TAFDSAESAHFWLDKLFLDIPRTLPIRLVGVTFSSLTSATQVTPQLNLFE

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=338, Percent_Identity=27.5147928994083, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI7706681, Length=339, Percent_Identity=27.4336283185841, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI154350220, Length=325, Percent_Identity=28.9230769230769, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=50.4672897196262, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI5729982, Length=117, Percent_Identity=38.4615384615385, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1786425, Length=305, Percent_Identity=46.2295081967213, Blast_Score=258, Evalue=6e-70,
Organism=Escherichia coli, GI1787432, Length=299, Percent_Identity=28.0936454849498, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17537959, Length=365, Percent_Identity=26.027397260274, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193205702, Length=274, Percent_Identity=30.2919708029197, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI193205700, Length=282, Percent_Identity=30.1418439716312, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI115534089, Length=125, Percent_Identity=40, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19923006, Length=341, Percent_Identity=26.9794721407625, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI21355641, Length=288, Percent_Identity=28.8194444444444, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24644984, Length=288, Percent_Identity=28.8194444444444, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24668444, Length=123, Percent_Identity=35.7723577235772, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 41095; Mature: 40964

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIHVTTTNTKPAVSQSNLRKIIHIDMDAFYASVEQRDFPELRGKPLVVGGDPNGRGVVA
CEEEEEECCCCCCCCHHCCEEEEEEEHHHHHHHHHHCCCHHHCCCEEEECCCCCCCEEEE
AASYEVRKFGVRSAMSCYEARKRCPEVIFVPPRFDVYRAVSVEIRRIMHILTPHVEPLSL
ECCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DEAYLDVTGLSVHQGSATLMANWLRAQILGQTGLNASAGVSFNKMLAKIASDINKPNGTA
CCHHEEEECEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCE
VITPADADAFISALPIERFHGIGKATAKRLHAMGVSNGADLRRTPAAILVNEFGKRGQFY
EEECCCHHHHHHHCCHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCH
HDIAHGRDERAVKSERTHKSVGSETTFRENLTDDNELKIQIYEQNADAFSQLHKKQLIAY
HHHHCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEEEEECCCHHHHHHHHHEEEEE
TITLKVKYSDFTQVTRSHTLSTAFDSAESAHFWLDKLFLDIPRTLPIRLVGVTFSSLTSA
EEEEEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHH
TQVTPQLNLFE
HHCCCCCCCCC
>Mature Secondary Structure 
TIHVTTTNTKPAVSQSNLRKIIHIDMDAFYASVEQRDFPELRGKPLVVGGDPNGRGVVA
EEEEEECCCCCCCCHHCCEEEEEEEHHHHHHHHHHCCCHHHCCCEEEECCCCCCCEEEE
AASYEVRKFGVRSAMSCYEARKRCPEVIFVPPRFDVYRAVSVEIRRIMHILTPHVEPLSL
ECCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DEAYLDVTGLSVHQGSATLMANWLRAQILGQTGLNASAGVSFNKMLAKIASDINKPNGTA
CCHHEEEECEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCE
VITPADADAFISALPIERFHGIGKATAKRLHAMGVSNGADLRRTPAAILVNEFGKRGQFY
EEECCCHHHHHHHCCHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCH
HDIAHGRDERAVKSERTHKSVGSETTFRENLTDDNELKIQIYEQNADAFSQLHKKQLIAY
HHHHCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEEEEECCCHHHHHHHHHEEEEE
TITLKVKYSDFTQVTRSHTLSTAFDSAESAHFWLDKLFLDIPRTLPIRLVGVTFSSLTSA
EEEEEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHH
TQVTPQLNLFE
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA