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The map label for this gene is benK [H]

Identifier: 93006085

GI number: 93006085

Start: 1527175

End: 1528539

Strand: Reverse

Name: benK [H]

Synonym: Pcryo_1257

Alternate gene names: 93006085

Gene position: 1528539-1527175 (Counterclockwise)

Preceding gene: 93006086

Following gene: 93006083

Centisome position: 49.95

GC content: 43.81

Gene sequence:

>1365_bases
ATGGAATCACCAACCATAAACATCAATAAAGTTATTGATGAAGCCAAATTTGCTCCTTTTCATTGGAAGGTGCTGTTTTG
GTGTCTATTGATCATTATCTTTGATGGTTATGATCTCATCATTTATGGAGTGGCCCTACCGTTACTCATGGAAGAATGGT
CATTGACCGCGGTACAAGCAGGCTTTCTTGCCAGCGCAGCACTTTTCGGCATGATGTTTGGTGCCATGATTTTTGGTACT
TTGTCTGATAAAATCGGTCGAAAAAAGACCATCATGATCTGCGTCGGTCTATTCAGTAGCTTTACCTTTTTCGGTGCTTT
TGCTAATGGTCCGATGCAGTTTGCAGCTTTACGCTTCATTGCTGGTCTTGGTATCGGCGGCGTGATGCCGATTTGTGTGG
CGCTGACCTCTGAATACGCCCCAAAGCGTATTCGTAGTACTCTAGTCGCTATTATGTTTAGTGGTTACGCGATCGGCGGT
ATGGCATCAGCATTATTGGGATCATTTTTGGTGGTAGATTACGGTTGGGAGATTATGTTTTATATTGCAGGCATCCCTAC
CTTACTCTTACCAATCATTTGGAAAATGCTGCCTGAATCCTTGATGTATTTGGTCAAAGAAAAAAGACATGATGAAGCCA
AAAAAATCGTCCGCAAACTTGCACCACAAGAGACTATCACAACCTCTACTGACTTAATCTTAGATGAGCCAACCAAAGGC
GATGACGCTCCTATCAAAGCGTTATTCCTAAAAAATAGAGGTTTTACCACCATCATGTTTTGGGTAGCTTTCTTTATGTG
CTTGTTGATGGTATATGCTCTCGCCAGCTGGTTACCAAAGCTTATGATTCAAGCAGGTTATTCACTAGGCGCTAGTATGC
TGTTCTTATTTGCGCTCAATATTGGCGGTATGGTCGGTGCTATTGGTGGCGGTGTGCTAGCCGATAGATTCCATCTAAAG
CCTGTATTAACCGTTATGTTTGTCGCTGGTGCAGCCGCGTTGATATTACTTGGCTACAATAGCCCTCAAGTGGTGCTATA
TACCCTAATCGCGATTGCAGGTGCTACTACTATCGGCTCACAGATTCTGCTCTATACCTTTGTTGCTCAGTATTATCCGA
CTGCTGTACGTACGACAGCTATGGGCTGGGCATCGGGTATCGGTCGCATTGGTGCTATCGTAGGTCCTATCTTGACTGGG
GCGCTACTCACGCTCGAGCTTAGCCACCAAACGAACTTCTTATTTATCGCCATACCAGGAATAATTGCAGCCGTTGCTAT
TTTCTTCGTAAACCTTAATGCAGCCGTAGATAGTAAAAAAATTCAAGAAAAACCAGTCACTTTAGACACACCTATAGCGA
CCTAA

Upstream 100 bases:

>100_bases
TTATAGGTATATATTTATACTTAGATGGTTTTTGACTTGCCCATCAGAAAACAATAACTTGTTAGATACTTATAAGGATA
TTACCCATGGAGAAATACGA

Downstream 100 bases:

>100_bases
ATTTGATTTCGACTCTATTTTAATTATACTTTACATTTGTATAACCTGATCGATCTGGCAGCATAAACGCAAGGCACTAA
ATGCTGCTAGACTTGAGGTT

Product: major facilitator transporter

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MESPTININKVIDEAKFAPFHWKVLFWCLLIIIFDGYDLIIYGVALPLLMEEWSLTAVQAGFLASAALFGMMFGAMIFGT
LSDKIGRKKTIMICVGLFSSFTFFGAFANGPMQFAALRFIAGLGIGGVMPICVALTSEYAPKRIRSTLVAIMFSGYAIGG
MASALLGSFLVVDYGWEIMFYIAGIPTLLLPIIWKMLPESLMYLVKEKRHDEAKKIVRKLAPQETITTSTDLILDEPTKG
DDAPIKALFLKNRGFTTIMFWVAFFMCLLMVYALASWLPKLMIQAGYSLGASMLFLFALNIGGMVGAIGGGVLADRFHLK
PVLTVMFVAGAAALILLGYNSPQVVLYTLIAIAGATTIGSQILLYTFVAQYYPTAVRTTAMGWASGIGRIGAIVGPILTG
ALLTLELSHQTNFLFIAIPGIIAAVAIFFVNLNAAVDSKKIQEKPVTLDTPIAT

Sequences:

>Translated_454_residues
MESPTININKVIDEAKFAPFHWKVLFWCLLIIIFDGYDLIIYGVALPLLMEEWSLTAVQAGFLASAALFGMMFGAMIFGT
LSDKIGRKKTIMICVGLFSSFTFFGAFANGPMQFAALRFIAGLGIGGVMPICVALTSEYAPKRIRSTLVAIMFSGYAIGG
MASALLGSFLVVDYGWEIMFYIAGIPTLLLPIIWKMLPESLMYLVKEKRHDEAKKIVRKLAPQETITTSTDLILDEPTKG
DDAPIKALFLKNRGFTTIMFWVAFFMCLLMVYALASWLPKLMIQAGYSLGASMLFLFALNIGGMVGAIGGGVLADRFHLK
PVLTVMFVAGAAALILLGYNSPQVVLYTLIAIAGATTIGSQILLYTFVAQYYPTAVRTTAMGWASGIGRIGAIVGPILTG
ALLTLELSHQTNFLFIAIPGIIAAVAIFFVNLNAAVDSKKIQEKPVTLDTPIAT
>Mature_454_residues
MESPTININKVIDEAKFAPFHWKVLFWCLLIIIFDGYDLIIYGVALPLLMEEWSLTAVQAGFLASAALFGMMFGAMIFGT
LSDKIGRKKTIMICVGLFSSFTFFGAFANGPMQFAALRFIAGLGIGGVMPICVALTSEYAPKRIRSTLVAIMFSGYAIGG
MASALLGSFLVVDYGWEIMFYIAGIPTLLLPIIWKMLPESLMYLVKEKRHDEAKKIVRKLAPQETITTSTDLILDEPTKG
DDAPIKALFLKNRGFTTIMFWVAFFMCLLMVYALASWLPKLMIQAGYSLGASMLFLFALNIGGMVGAIGGGVLADRFHLK
PVLTVMFVAGAAALILLGYNSPQVVLYTLIAIAGATTIGSQILLYTFVAQYYPTAVRTTAMGWASGIGRIGAIVGPILTG
ALLTLELSHQTNFLFIAIPGIIAAVAIFFVNLNAAVDSKKIQEKPVTLDTPIAT

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=421, Percent_Identity=25.8907363420428, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI7662270, Length=254, Percent_Identity=25.9842519685039, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI216548223, Length=223, Percent_Identity=25.5605381165919, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI73695465, Length=221, Percent_Identity=25.7918552036199, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4507005, Length=379, Percent_Identity=24.0105540897098, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI24497490, Length=376, Percent_Identity=25.2659574468085, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI213021148, Length=432, Percent_Identity=21.9907407407407, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI262399383, Length=195, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI166064021, Length=366, Percent_Identity=26.2295081967213, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI31542327, Length=343, Percent_Identity=24.4897959183673, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI211059435, Length=380, Percent_Identity=26.5789473684211, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI203098995, Length=199, Percent_Identity=28.1407035175879, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI8923870, Length=372, Percent_Identity=26.0752688172043, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081723, Length=422, Percent_Identity=30.0947867298578, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1786229, Length=396, Percent_Identity=26.2626262626263, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI87082159, Length=390, Percent_Identity=27.9487179487179, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI87082404, Length=385, Percent_Identity=24.9350649350649, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082231, Length=429, Percent_Identity=23.5431235431235, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788074, Length=368, Percent_Identity=25.2717391304348, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1789312, Length=317, Percent_Identity=27.4447949526814, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788068, Length=425, Percent_Identity=23.0588235294118, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789207, Length=313, Percent_Identity=23.961661341853, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790463, Length=360, Percent_Identity=21.9444444444444, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=421, Percent_Identity=22.8028503562945, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71989525, Length=381, Percent_Identity=24.4094488188976, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71989531, Length=381, Percent_Identity=24.4094488188976, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25145172, Length=353, Percent_Identity=24.0793201133144, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560496, Length=365, Percent_Identity=21.6438356164384, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320595, Length=193, Percent_Identity=29.5336787564767, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324400, Length=180, Percent_Identity=28.3333333333333, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI19922874, Length=438, Percent_Identity=22.3744292237443, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24640198, Length=264, Percent_Identity=24.6212121212121, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640196, Length=264, Percent_Identity=24.6212121212121, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640200, Length=264, Percent_Identity=24.6212121212121, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24649618, Length=376, Percent_Identity=26.5957446808511, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI19922616, Length=369, Percent_Identity=24.9322493224932, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI62484254, Length=394, Percent_Identity=24.8730964467005, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24649622, Length=389, Percent_Identity=23.6503856041131, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24668440, Length=361, Percent_Identity=22.4376731301939, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49181; Mature: 49181

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESPTININKVIDEAKFAPFHWKVLFWCLLIIIFDGYDLIIYGVALPLLMEEWSLTAVQA
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GFLASAALFGMMFGAMIFGTLSDKIGRKKTIMICVGLFSSFTFFGAFANGPMQFAALRFI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AGLGIGGVMPICVALTSEYAPKRIRSTLVAIMFSGYAIGGMASALLGSFLVVDYGWEIMF
HHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHH
YIAGIPTLLLPIIWKMLPESLMYLVKEKRHDEAKKIVRKLAPQETITTSTDLILDEPTKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCC
DDAPIKALFLKNRGFTTIMFWVAFFMCLLMVYALASWLPKLMIQAGYSLGASMLFLFALN
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
IGGMVGAIGGGVLADRFHLKPVLTVMFVAGAAALILLGYNSPQVVLYTLIAIAGATTIGS
HCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHH
QILLYTFVAQYYPTAVRTTAMGWASGIGRIGAIVGPILTGALLTLELSHQTNFLFIAIPG
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEHHH
IIAAVAIFFVNLNAAVDSKKIQEKPVTLDTPIAT
HHHHHHHHHHHCCHHHCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MESPTININKVIDEAKFAPFHWKVLFWCLLIIIFDGYDLIIYGVALPLLMEEWSLTAVQA
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GFLASAALFGMMFGAMIFGTLSDKIGRKKTIMICVGLFSSFTFFGAFANGPMQFAALRFI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AGLGIGGVMPICVALTSEYAPKRIRSTLVAIMFSGYAIGGMASALLGSFLVVDYGWEIMF
HHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHH
YIAGIPTLLLPIIWKMLPESLMYLVKEKRHDEAKKIVRKLAPQETITTSTDLILDEPTKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCC
DDAPIKALFLKNRGFTTIMFWVAFFMCLLMVYALASWLPKLMIQAGYSLGASMLFLFALN
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
IGGMVGAIGGGVLADRFHLKPVLTVMFVAGAAALILLGYNSPQVVLYTLIAIAGATTIGS
HCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHH
QILLYTFVAQYYPTAVRTTAMGWASGIGRIGAIVGPILTGALLTLELSHQTNFLFIAIPG
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEHHH
IIAAVAIFFVNLNAAVDSKKIQEKPVTLDTPIAT
HHHHHHHHHHHCCHHHCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]