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The map label for this gene is bsaA [H]

Identifier: 93005524

GI number: 93005524

Start: 824511

End: 824996

Strand: Direct

Name: bsaA [H]

Synonym: Pcryo_0694

Alternate gene names: 93005524

Gene position: 824511-824996 (Clockwise)

Preceding gene: 93005523

Following gene: 93005532

Centisome position: 26.95

GC content: 40.12

Gene sequence:

>486_bases
ATGACTACTATTTATGATTTTAATGCTGAGCGTATCGATGGAACGACAAAAAGTTTCTCTGACTATAAAGATCAAGTGTT
GCTAATTGTTAATACCGCAAGCAAGTGTGGCTTTACGCCGCAGTTTGAGGGCTTAGAAGCACTGTTTCAGCAATATAAAG
ACCAAGGTTTAATGGTTATCGGTTTTCCCTGTAATCAATTCGGCAACCAAGATCCTGCTAATAATGATGAAATTGGTGAA
TTTTGCCAAAAGAACTATGGTGTGAGCTTTCCAATGATGGCAAAAGTCGACGTCAATGGTGGTGATGCTCATCCTGTGTT
TGAATGGCTAAAAAATCAAAAAGGCGGGCTTCTCACAGATGGTATCAAATGGAATTTCACCAAGTTTTTAATTGATAGTA
AAGGGCAGGTAATTGCTCGTTATGCACCAACGACCAAACCTGAAGCGCTCAAGGCTGATATAGAACAAGCGCTGGCTGCA
AAGTAA

Upstream 100 bases:

>100_bases
ACTTATTATTAATATCAGTAAGTTTATTAATAACAGTGTCTTAAGTACTATAGTGCATGATGCTTGATAGCGAAAAAAAT
AACTCATTTAAGGATGAATA

Downstream 100 bases:

>100_bases
GTACTAGAGTGAAAAAGATTAACTATTCTGCGAAATTATAAAATCAATTAAAACAGATGCTTATAAATTTAATCACCAAA
ATAAGCAAAAATCTGTGATA

Product: glutathione peroxidase

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTTIYDFNAERIDGTTKSFSDYKDQVLLIVNTASKCGFTPQFEGLEALFQQYKDQGLMVIGFPCNQFGNQDPANNDEIGE
FCQKNYGVSFPMMAKVDVNGGDAHPVFEWLKNQKGGLLTDGIKWNFTKFLIDSKGQVIARYAPTTKPEALKADIEQALAA
K

Sequences:

>Translated_161_residues
MTTIYDFNAERIDGTTKSFSDYKDQVLLIVNTASKCGFTPQFEGLEALFQQYKDQGLMVIGFPCNQFGNQDPANNDEIGE
FCQKNYGVSFPMMAKVDVNGGDAHPVFEWLKNQKGGLLTDGIKWNFTKFLIDSKGQVIARYAPTTKPEALKADIEQALAA
K
>Mature_160_residues
TTIYDFNAERIDGTTKSFSDYKDQVLLIVNTASKCGFTPQFEGLEALFQQYKDQGLMVIGFPCNQFGNQDPANNDEIGEF
CQKNYGVSFPMMAKVDVNGGDAHPVFEWLKNQKGGLLTDGIKWNFTKFLIDSKGQVIARYAPTTKPEALKADIEQALAAK

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=157, Percent_Identity=43.312101910828, Blast_Score=134, Evalue=3e-32,
Organism=Homo sapiens, GI90903240, Length=155, Percent_Identity=43.8709677419355, Blast_Score=133, Evalue=6e-32,
Organism=Homo sapiens, GI15618997, Length=151, Percent_Identity=41.0596026490066, Blast_Score=123, Evalue=6e-29,
Organism=Homo sapiens, GI90903238, Length=130, Percent_Identity=44.6153846153846, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI192455698, Length=155, Percent_Identity=34.1935483870968, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI4557629, Length=173, Percent_Identity=35.2601156069364, Blast_Score=94, Evalue=4e-20,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=32.5966850828729, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI6006001, Length=173, Percent_Identity=35.2601156069364, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI41406084, Length=183, Percent_Identity=31.6939890710383, Blast_Score=84, Evalue=6e-17,
Organism=Homo sapiens, GI33186887, Length=177, Percent_Identity=32.2033898305085, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1788003, Length=170, Percent_Identity=40, Blast_Score=135, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17506887, Length=162, Percent_Identity=45.0617283950617, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17535473, Length=162, Percent_Identity=42.5925925925926, Blast_Score=145, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI71993584, Length=159, Percent_Identity=38.3647798742138, Blast_Score=133, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI193210707, Length=161, Percent_Identity=40.3726708074534, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI193209493, Length=181, Percent_Identity=34.2541436464088, Blast_Score=106, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17550320, Length=181, Percent_Identity=32.5966850828729, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=38.9473684210526, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=38.1578947368421, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=54.0880503144654, Blast_Score=188, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6319721, Length=159, Percent_Identity=51.5723270440252, Blast_Score=184, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6322826, Length=159, Percent_Identity=42.7672955974843, Blast_Score=146, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24656772, Length=158, Percent_Identity=43.6708860759494, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24656767, Length=158, Percent_Identity=43.6708860759494, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24656777, Length=158, Percent_Identity=43.6708860759494, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=38.3647798742138, Blast_Score=113, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 17920; Mature: 17789

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIYDFNAERIDGTTKSFSDYKDQVLLIVNTASKCGFTPQFEGLEALFQQYKDQGLMVI
CCEEECCCCHHCCCCCCCCCCCCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHCCCEEEE
GFPCNQFGNQDPANNDEIGEFCQKNYGVSFPMMAKVDVNGGDAHPVFEWLKNQKGGLLTD
ECCCHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEC
GIKWNFTKFLIDSKGQVIARYAPTTKPEALKADIEQALAAK
CCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTIYDFNAERIDGTTKSFSDYKDQVLLIVNTASKCGFTPQFEGLEALFQQYKDQGLMVI
CEEECCCCHHCCCCCCCCCCCCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHCCCEEEE
GFPCNQFGNQDPANNDEIGEFCQKNYGVSFPMMAKVDVNGGDAHPVFEWLKNQKGGLLTD
ECCCHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEC
GIKWNFTKFLIDSKGQVIARYAPTTKPEALKADIEQALAAK
CCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10086841; 11058132 [H]