Click here to switch to the map view.

The map label for this gene is dacC [H]

Identifier: 93005266

GI number: 93005266

Start: 532548

End: 534671

Strand: Reverse

Name: dacC [H]

Synonym: Pcryo_0436

Alternate gene names: 93005266

Gene position: 534671-532548 (Counterclockwise)

Preceding gene: 93005267

Following gene: 93005265

Centisome position: 17.47

GC content: 44.02

Gene sequence:

>2124_bases
ATGCTACAGCTACGCGAAAACAGTAACTCATGTTACCATAGCCTGTTTTTGCCACCTGATGATAGGCTGCTCATGCGCTC
CTTAGTAAAACCAACTCTACTTAGAACTCATAACCCTTCTATACGCACAACAGCCATTAGCCAATATTTGCAAACGCTGA
AAAATATCGGTCAACGTCTATCTTTATTGGCATTAGTTGTCGCTCCTACCTTAGTGCCATTACATCTGCACGCTGCCTTA
CCGCAAGAGATTGAAACGGCATTAGCGCGAGCCCATTTAAGCGCAGCAGACATCAGTATTGTCATTACGCCAGTGGGTGA
CAAAAACGCCAGCCGCTTGCCCTCTGCCGTTCAGGTTATCGACAGGAAAAAGGCGGTCAATCAATTGCAGCCTGCAAGCT
CAGACGAGATAAATACTGATGCCAATAACAGCAAGCAAAAACTGGTTCGAAACAAGCAGAGTCCTAAGCCGTTAGCCAAT
TACCAAAGCGCGTTAGTAACCATCGAAAAGCAAACCATCAGACAGCACGACAGACAATTACACGCTTATACCGATGATCC
TTATACCCACCAAAGCTTGATGAGTACTCCGTCATTACTGCCAGAAAACGTGTTAAATACTGCTAATTATTCTTCCAGTC
AGAACGACAATATCAGTGCTAACGGCGCAGATAATAATAACAGCGACAATAAAAAATCTGACAGTGAGACCTCAATAAAA
ATATCGTTTTCGCCATTACTCAATCATCAGCCTGACATAGCACGTACGCCCGCCAGCACGATGAAACTCGTTCCTAGCTT
TATTGCCTTAGATATCTTAGGCGCTGACTTTGTCTGGCATACGCGCGTTTATCATACTGGTATTATCATTGGTAATACAT
TGCTTGGTGATTTGATAATTCAAGGCAGTGGCGACCCAAAAATGACCCATGAGCGCTTACAGCAATTGCTCTATAAAGTG
AAAGCAGCAGGCATCCGTCATATCGATGGCGATATCATTGTAGATAGCACTATTTTTAACCATGTCACTAAAGATCCTGC
GGCATTTGATAACGCGCCTTTACGTCCTTATAACGCCAGTCCCGATGGTTTTCTGGTCAATTTCAGTACTATTGGTATCC
AAAGCTATCCATTAAATAATGCCCAAGCACAGCTGACTTATACGCCGCAGCTGGCAGATTATAAGTTGCCAAGTAAGATA
AATATACGCCCCTCTGCCTGTGGTCAAGCACGTTATAGCTTAGCGCCGCAGTGGCAAGCAACTCAGCTGACCTTTGATAC
CTCTTTACCCGATAACTGCGGCAACCATGCTTTTTATGTCGCTTATCCTGATGCCAAAGATTTTGCGGCTCGCGTGATCA
AAGCCAAATGGCAAGCACTGGATAATACGCTAACGGGCAACGTTGTCGCTCAAGAAACACCATATAAGAATAAGAAATCC
ATATCAGCGCGCGGTTTGGCAGCTCTACCAATGTCGCCTTTACCAATTGTTAGTTATCCTTCTTTAAACTTAACGCAGCA
AATTTATGATATCAATCATTTCTCTAATAATGTGATGACTGAACAAGTGGCGCTATCAATAGGCGCTTATCATAAACCCA
AAGATGAAACCGTTAATCCAACCATTAATAAAAACGTCGATAAAGCTATTAATAGTCAGCACAGCTTATATCAATTTGGT
AAGCCTGCGACAACGAGCTACCCTGCTGCCTTACAAACCATCAACGAATGGTGGCAAACGCATCTAAGCACGCCGCCGCC
ACATCTGACCAATGGTTCTGGGTTGTGCCGTGATTGTACTATCAGCGCTGCTAATCTAAGCGAGCTGCTGACTTATGCTT
ACGCTCACCCAAGCTTTAATGCTTATGTAAACTCGTTAGGTATTGCTGGCGTCAGTGGCACCATTTTGACACATAGCGAG
CGTTTACCAGAATCAAACGCCATTGGTCGAGCTTGGATAAAAACAGGTACTTTAAACAATGTCACTTCGATGGCAGGCTA
TGTCAAAGGCTTATCAGGACAGGATTATGTGGTAGTGGGACTGATCAATAATGAGCAAGCGCTAAATACTTATACAGCAA
GAACGGTACTGGACGCCATGCTAGATTGGACAGCGCAGCATTAA

Upstream 100 bases:

>100_bases
CAATGGCATTTTTGCATATGCGCTAATATAATGGCTAAAATGCATTATTTAGACAAGGCTTTAAGATAAAAGATTAAAAT
AAAAGCACGCTTACAACTAC

Downstream 100 bases:

>100_bases
TTTTTTACGCCAGATTATTTACTTTATAAAGGACATTTTATGTCACGTAAGCCCGCGTCACTTAGCAAACCTATCACCCC
ATCAGGACGTAAAGGATCAC

Product: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 4a; PBP-4a [H]

Number of amino acids: Translated: 707; Mature: 707

Protein sequence:

>707_residues
MLQLRENSNSCYHSLFLPPDDRLLMRSLVKPTLLRTHNPSIRTTAISQYLQTLKNIGQRLSLLALVVAPTLVPLHLHAAL
PQEIETALARAHLSAADISIVITPVGDKNASRLPSAVQVIDRKKAVNQLQPASSDEINTDANNSKQKLVRNKQSPKPLAN
YQSALVTIEKQTIRQHDRQLHAYTDDPYTHQSLMSTPSLLPENVLNTANYSSSQNDNISANGADNNNSDNKKSDSETSIK
ISFSPLLNHQPDIARTPASTMKLVPSFIALDILGADFVWHTRVYHTGIIIGNTLLGDLIIQGSGDPKMTHERLQQLLYKV
KAAGIRHIDGDIIVDSTIFNHVTKDPAAFDNAPLRPYNASPDGFLVNFSTIGIQSYPLNNAQAQLTYTPQLADYKLPSKI
NIRPSACGQARYSLAPQWQATQLTFDTSLPDNCGNHAFYVAYPDAKDFAARVIKAKWQALDNTLTGNVVAQETPYKNKKS
ISARGLAALPMSPLPIVSYPSLNLTQQIYDINHFSNNVMTEQVALSIGAYHKPKDETVNPTINKNVDKAINSQHSLYQFG
KPATTSYPAALQTINEWWQTHLSTPPPHLTNGSGLCRDCTISAANLSELLTYAYAHPSFNAYVNSLGIAGVSGTILTHSE
RLPESNAIGRAWIKTGTLNNVTSMAGYVKGLSGQDYVVVGLINNEQALNTYTARTVLDAMLDWTAQH

Sequences:

>Translated_707_residues
MLQLRENSNSCYHSLFLPPDDRLLMRSLVKPTLLRTHNPSIRTTAISQYLQTLKNIGQRLSLLALVVAPTLVPLHLHAAL
PQEIETALARAHLSAADISIVITPVGDKNASRLPSAVQVIDRKKAVNQLQPASSDEINTDANNSKQKLVRNKQSPKPLAN
YQSALVTIEKQTIRQHDRQLHAYTDDPYTHQSLMSTPSLLPENVLNTANYSSSQNDNISANGADNNNSDNKKSDSETSIK
ISFSPLLNHQPDIARTPASTMKLVPSFIALDILGADFVWHTRVYHTGIIIGNTLLGDLIIQGSGDPKMTHERLQQLLYKV
KAAGIRHIDGDIIVDSTIFNHVTKDPAAFDNAPLRPYNASPDGFLVNFSTIGIQSYPLNNAQAQLTYTPQLADYKLPSKI
NIRPSACGQARYSLAPQWQATQLTFDTSLPDNCGNHAFYVAYPDAKDFAARVIKAKWQALDNTLTGNVVAQETPYKNKKS
ISARGLAALPMSPLPIVSYPSLNLTQQIYDINHFSNNVMTEQVALSIGAYHKPKDETVNPTINKNVDKAINSQHSLYQFG
KPATTSYPAALQTINEWWQTHLSTPPPHLTNGSGLCRDCTISAANLSELLTYAYAHPSFNAYVNSLGIAGVSGTILTHSE
RLPESNAIGRAWIKTGTLNNVTSMAGYVKGLSGQDYVVVGLINNEQALNTYTARTVLDAMLDWTAQH
>Mature_707_residues
MLQLRENSNSCYHSLFLPPDDRLLMRSLVKPTLLRTHNPSIRTTAISQYLQTLKNIGQRLSLLALVVAPTLVPLHLHAAL
PQEIETALARAHLSAADISIVITPVGDKNASRLPSAVQVIDRKKAVNQLQPASSDEINTDANNSKQKLVRNKQSPKPLAN
YQSALVTIEKQTIRQHDRQLHAYTDDPYTHQSLMSTPSLLPENVLNTANYSSSQNDNISANGADNNNSDNKKSDSETSIK
ISFSPLLNHQPDIARTPASTMKLVPSFIALDILGADFVWHTRVYHTGIIIGNTLLGDLIIQGSGDPKMTHERLQQLLYKV
KAAGIRHIDGDIIVDSTIFNHVTKDPAAFDNAPLRPYNASPDGFLVNFSTIGIQSYPLNNAQAQLTYTPQLADYKLPSKI
NIRPSACGQARYSLAPQWQATQLTFDTSLPDNCGNHAFYVAYPDAKDFAARVIKAKWQALDNTLTGNVVAQETPYKNKKS
ISARGLAALPMSPLPIVSYPSLNLTQQIYDINHFSNNVMTEQVALSIGAYHKPKDETVNPTINKNVDKAINSQHSLYQFG
KPATTSYPAALQTINEWWQTHLSTPPPHLTNGSGLCRDCTISAANLSELLTYAYAHPSFNAYVNSLGIAGVSGTILTHSE
RLPESNAIGRAWIKTGTLNNVTSMAGYVKGLSGQDYVVVGLINNEQALNTYTARTVLDAMLDWTAQH

Specific function: Catalyzes DD-carboxypeptidase and transpeptidation reactions [H]

COG id: COG2027

COG function: function code M; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)

Gene ontology:

Cell location: Secreted (Probable). Note=May be anchored in the membrane via a C-terminal amphiphatic alpha helix [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S13 family [H]

Homologues:

Organism=Escherichia coli, GI1789573, Length=446, Percent_Identity=21.52466367713, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR000667 [H]

Pfam domain/function: PF02113 Peptidase_S13 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 77560; Mature: 77560

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQLRENSNSCYHSLFLPPDDRLLMRSLVKPTLLRTHNPSIRTTAISQYLQTLKNIGQRL
CCEEECCCCCEEEEEECCCCHHHHHHHHHCHHHEECCCCCHHHHHHHHHHHHHHHHHHHH
SLLALVVAPTLVPLHLHAALPQEIETALARAHLSAADISIVITPVGDKNASRLPSAVQVI
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHCHHHHHHH
DRKKAVNQLQPASSDEINTDANNSKQKLVRNKQSPKPLANYQSALVTIEKQTIRQHDRQL
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHEEEHHHHHHHHHCEE
HAYTDDPYTHQSLMSTPSLLPENVLNTANYSSSQNDNISANGADNNNSDNKKSDSETSIK
EEECCCCCHHHHHHCCCCCCHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEE
ISFSPLLNHQPDIARTPASTMKLVPSFIALDILGADFVWHTRVYHTGIIIGNTLLGDLII
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHEECEEEECCHHEEEEEE
QGSGDPKMTHERLQQLLYKVKAAGIRHIDGDIIVDSTIFNHVTKDPAAFDNAPLRPYNAS
ECCCCCHHHHHHHHHHHHHHHHCCCEECCCCEEECHHHHHHHCCCCCCCCCCCCCCCCCC
PDGFLVNFSTIGIQSYPLNNAQAQLTYTPQLADYKLPSKINIRPSACGQARYSLAPQWQA
CCCEEEEEEEECEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCE
TQLTFDTSLPDNCGNHAFYVAYPDAKDFAARVIKAKWQALDNTLTGNVVAQETPYKNKKS
EEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCC
ISARGLAALPMSPLPIVSYPSLNLTQQIYDINHFSNNVMTEQVALSIGAYHKPKDETVNP
CCCCCEEECCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCC
TINKNVDKAINSQHSLYQFGKPATTSYPAALQTINEWWQTHLSTPPPHLTNGSGLCRDCT
CCCCCHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
ISAANLSELLTYAYAHPSFNAYVNSLGIAGVSGTILTHSERLPESNAIGRAWIKTGTLNN
ECHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEEECHHHCCCCCCCCCCEEECCCCCH
VTSMAGYVKGLSGQDYVVVGLINNEQALNTYTARTVLDAMLDWTAQH
HHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLQLRENSNSCYHSLFLPPDDRLLMRSLVKPTLLRTHNPSIRTTAISQYLQTLKNIGQRL
CCEEECCCCCEEEEEECCCCHHHHHHHHHCHHHEECCCCCHHHHHHHHHHHHHHHHHHHH
SLLALVVAPTLVPLHLHAALPQEIETALARAHLSAADISIVITPVGDKNASRLPSAVQVI
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHCHHHHHHH
DRKKAVNQLQPASSDEINTDANNSKQKLVRNKQSPKPLANYQSALVTIEKQTIRQHDRQL
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHEEEHHHHHHHHHCEE
HAYTDDPYTHQSLMSTPSLLPENVLNTANYSSSQNDNISANGADNNNSDNKKSDSETSIK
EEECCCCCHHHHHHCCCCCCHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEE
ISFSPLLNHQPDIARTPASTMKLVPSFIALDILGADFVWHTRVYHTGIIIGNTLLGDLII
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHEECEEEECCHHEEEEEE
QGSGDPKMTHERLQQLLYKVKAAGIRHIDGDIIVDSTIFNHVTKDPAAFDNAPLRPYNAS
ECCCCCHHHHHHHHHHHHHHHHCCCEECCCCEEECHHHHHHHCCCCCCCCCCCCCCCCCC
PDGFLVNFSTIGIQSYPLNNAQAQLTYTPQLADYKLPSKINIRPSACGQARYSLAPQWQA
CCCEEEEEEEECEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCE
TQLTFDTSLPDNCGNHAFYVAYPDAKDFAARVIKAKWQALDNTLTGNVVAQETPYKNKKS
EEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCC
ISARGLAALPMSPLPIVSYPSLNLTQQIYDINHFSNNVMTEQVALSIGAYHKPKDETVNP
CCCCCEEECCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCC
TINKNVDKAINSQHSLYQFGKPATTSYPAALQTINEWWQTHLSTPPPHLTNGSGLCRDCT
CCCCCHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
ISAANLSELLTYAYAHPSFNAYVNSLGIAGVSGTILTHSERLPESNAIGRAWIKTGTLNN
ECHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEEECHHHCCCCCCCCCCEEECCCCCH
VTSMAGYVKGLSGQDYVVVGLINNEQALNTYTARTVLDAMLDWTAQH
HHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7711903; 9384377 [H]