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The map label for this gene is lspA [H]

Identifier: 93005231

GI number: 93005231

Start: 486145

End: 486795

Strand: Reverse

Name: lspA [H]

Synonym: Pcryo_0401

Alternate gene names: 93005231

Gene position: 486795-486145 (Counterclockwise)

Preceding gene: 93005232

Following gene: 93005229

Centisome position: 15.91

GC content: 43.93

Gene sequence:

>651_bases
ATGCCTAATACAACACCCAATCCAACGCCTAATCCAACAAATTTGCCTGACGATAAGCAAGTGCCTATCGACGTCGACAG
TTCACCTAAACCGGCTCATGCCACTACGGGTAGCTCATCGACGCCGAAGAGTCGATTGAACAAGACGCCAAAGATGATCG
CTAATGGTCGTCTTGCGCTTAACTGGTATCTGTTGTCACTGGTCGTGATTATCCTTGATCAATGGACAAAATGGCTCGCA
GAAACCAATCTGACCTTCCTTGAACCTGTGCCTGTGATTGAGCCGTTTTTAAACTGGACGCTCGCTTACAACTACGGTGC
TGCTTTTAGCTTTTTGGCAGATGCAGGCGGTTGGCAAAAGTGGTTTTTTTCAGGGCTGGCACTATTGATGTCGCTATTCT
TGATAGGCTATCTAGCTAAAGCGCCCCGTCAAGCTAAGCTGTTATCACTAGGTTTGGCATTGGTATTAGGCGGTGCCGTG
GGCAATTTAATCGATCGCTTATTACATGGTCACGTCATTGATTTTATACATGTGCATTATGCTGATGTTTGGCATTATCC
CATTTTTAATATTGCTGATATTGGCATTTCTATCGGTGTATTATTGATTGTCATCGATATGCTGTTTTTGGAAAAAAAGC
GTGAAGTTTAA

Upstream 100 bases:

>100_bases
TGTTGGCATATCCGTGATGACATTGGCACAGATAGCGCACATCCAGAATTATGTGCGCGCTGTGTAACCAACGTCAGCGG
TGATGGAGAGGTGCGCCACT

Downstream 100 bases:

>100_bases
CGCGTCTCAAGGCATATCGCTTTATTAATAGAAAAGGTGGATTGCATTTTTGTAAATCCACCTTTTCTTTGGCTTTTATT
CTCACTATCTAAAACCTATA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MPNTTPNPTPNPTNLPDDKQVPIDVDSSPKPAHATTGSSSTPKSRLNKTPKMIANGRLALNWYLLSLVVIILDQWTKWLA
ETNLTFLEPVPVIEPFLNWTLAYNYGAAFSFLADAGGWQKWFFSGLALLMSLFLIGYLAKAPRQAKLLSLGLALVLGGAV
GNLIDRLLHGHVIDFIHVHYADVWHYPIFNIADIGISIGVLLIVIDMLFLEKKREV

Sequences:

>Translated_216_residues
MPNTTPNPTPNPTNLPDDKQVPIDVDSSPKPAHATTGSSSTPKSRLNKTPKMIANGRLALNWYLLSLVVIILDQWTKWLA
ETNLTFLEPVPVIEPFLNWTLAYNYGAAFSFLADAGGWQKWFFSGLALLMSLFLIGYLAKAPRQAKLLSLGLALVLGGAV
GNLIDRLLHGHVIDFIHVHYADVWHYPIFNIADIGISIGVLLIVIDMLFLEKKREV
>Mature_215_residues
PNTTPNPTPNPTNLPDDKQVPIDVDSSPKPAHATTGSSSTPKSRLNKTPKMIANGRLALNWYLLSLVVIILDQWTKWLAE
TNLTFLEPVPVIEPFLNWTLAYNYGAAFSFLADAGGWQKWFFSGLALLMSLFLIGYLAKAPRQAKLLSLGLALVLGGAVG
NLIDRLLHGHVIDFIHVHYADVWHYPIFNIADIGISIGVLLIVIDMLFLEKKREV

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=157, Percent_Identity=43.312101910828, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 23927; Mature: 23796

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNTTPNPTPNPTNLPDDKQVPIDVDSSPKPAHATTGSSSTPKSRLNKTPKMIANGRLAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHCCCHHH
NWYLLSLVVIILDQWTKWLAETNLTFLEPVPVIEPFLNWTLAYNYGAAFSFLADAGGWQK
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHH
WFFSGLALLMSLFLIGYLAKAPRQAKLLSLGLALVLGGAVGNLIDRLLHGHVIDFIHVHY
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADVWHYPIFNIADIGISIGVLLIVIDMLFLEKKREV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PNTTPNPTPNPTNLPDDKQVPIDVDSSPKPAHATTGSSSTPKSRLNKTPKMIANGRLAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHCCCHHH
NWYLLSLVVIILDQWTKWLAETNLTFLEPVPVIEPFLNWTLAYNYGAAFSFLADAGGWQK
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHH
WFFSGLALLMSLFLIGYLAKAPRQAKLLSLGLALVLGGAVGNLIDRLLHGHVIDFIHVHY
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADVWHYPIFNIADIGISIGVLLIVIDMLFLEKKREV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA