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The map label for this gene is cidB [H]

Identifier: 93005224

GI number: 93005224

Start: 479365

End: 480054

Strand: Reverse

Name: cidB [H]

Synonym: Pcryo_0394

Alternate gene names: 93005224

Gene position: 480054-479365 (Counterclockwise)

Preceding gene: 93005225

Following gene: 93005223

Centisome position: 15.69

GC content: 43.19

Gene sequence:

>690_bases
ATGAGTTTTGATAATGTGTTTGTGGCAACCTTTACCGCGATATTACTGACTTTAGCAGCCCATGTAATTGCTCGCATATT
GGCACGCAAACTTTCATGGTTACCGATGGTCATTACCGCACTAGTATTGGTCGTTATATTTCTATTCATTTTCCAATGGG
ATTACAATCATTATTATGCCGTAGCCAAACCCGTTTTTGACCATCTATTAGGTTATGTCACTGTCTTATTGGCAATACCT
TTGGCTGCCATGAATTTCAAAGGTTTACCTATCAAGAAACTTGTCTTAATTGTGGCGATGGCGAGTTTGATTGGCGCATT
ATTACCGATGTCATTAGCCTATCTATTTTCACTCAGTCACGATACGATATTAGCATTTGCCAGTCGTTCAGTGACCACGC
CGATTGGTCTGAGCATCGCAGATTTAATCAAAGCACCTCTAGCGATGGCAAACCTGATTATTATCGTTTCAGGCCTCATT
GGCGGGACATTAGCGCGTTTCTTATTTATTGGCATTGAAGATGACCGTGCTAAAGGCTTAGCGCTTGGCTTAGTTGCTCA
TGCGTTCGGCACCGTAGAAGCATGGCAAATCAGTCATACAGCGGGCAGATATGCCGCGTTTGGCTTGGCAGTGAATGGTT
TGGTCACTGCTGTCTGGGTACCTATATTTATCACAGCACTGTCTGCTTAA

Upstream 100 bases:

>100_bases
TTATCCAATCGTTGGCTGAACCGTAATAATGATATGAACGGCAACACTACCATTAATGAGCAAAAATGACAGCCTTGAGC
GGTATGGATAAAGGAATTTT

Downstream 100 bases:

>100_bases
TTGTCCTTTAATATAGCACTGCTATTCTATAGTCAATTCCAAATAAAACAGATACGTTATGTTCCAACGCAGTACTGGTA
TAAATTTTTCTGGCGTGCTG

Product: LrgB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSFDNVFVATFTAILLTLAAHVIARILARKLSWLPMVITALVLVVIFLFIFQWDYNHYYAVAKPVFDHLLGYVTVLLAIP
LAAMNFKGLPIKKLVLIVAMASLIGALLPMSLAYLFSLSHDTILAFASRSVTTPIGLSIADLIKAPLAMANLIIIVSGLI
GGTLARFLFIGIEDDRAKGLALGLVAHAFGTVEAWQISHTAGRYAAFGLAVNGLVTAVWVPIFITALSA

Sequences:

>Translated_229_residues
MSFDNVFVATFTAILLTLAAHVIARILARKLSWLPMVITALVLVVIFLFIFQWDYNHYYAVAKPVFDHLLGYVTVLLAIP
LAAMNFKGLPIKKLVLIVAMASLIGALLPMSLAYLFSLSHDTILAFASRSVTTPIGLSIADLIKAPLAMANLIIIVSGLI
GGTLARFLFIGIEDDRAKGLALGLVAHAFGTVEAWQISHTAGRYAAFGLAVNGLVTAVWVPIFITALSA
>Mature_228_residues
SFDNVFVATFTAILLTLAAHVIARILARKLSWLPMVITALVLVVIFLFIFQWDYNHYYAVAKPVFDHLLGYVTVLLAIPL
AAMNFKGLPIKKLVLIVAMASLIGALLPMSLAYLFSLSHDTILAFASRSVTTPIGLSIADLIKAPLAMANLIIIVSGLIG
GTLARFLFIGIEDDRAKGLALGLVAHAFGTVEAWQISHTAGRYAAFGLAVNGLVTAVWVPIFITALSA

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins.

COG id: COG1346

COG function: function code M; Putative effector of murein hydrolase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidB/LrgB family. CidB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788464, Length=211, Percent_Identity=27.0142180094787, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007300 [H]

Pfam domain/function: PF04172 LrgB [H]

EC number: NA

Molecular weight: Translated: 24579; Mature: 24448

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDNVFVATFTAILLTLAAHVIARILARKLSWLPMVITALVLVVIFLFIFQWDYNHYYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VAKPVFDHLLGYVTVLLAIPLAAMNFKGLPIKKLVLIVAMASLIGALLPMSLAYLFSLSH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DTILAFASRSVTTPIGLSIADLIKAPLAMANLIIIVSGLIGGTLARFLFIGIEDDRAKGL
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ALGLVAHAFGTVEAWQISHTAGRYAAFGLAVNGLVTAVWVPIFITALSA
HHHHHHHHHCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SFDNVFVATFTAILLTLAAHVIARILARKLSWLPMVITALVLVVIFLFIFQWDYNHYYA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VAKPVFDHLLGYVTVLLAIPLAAMNFKGLPIKKLVLIVAMASLIGALLPMSLAYLFSLSH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DTILAFASRSVTTPIGLSIADLIKAPLAMANLIIIVSGLIGGTLARFLFIGIEDDRAKGL
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ALGLVAHAFGTVEAWQISHTAGRYAAFGLAVNGLVTAVWVPIFITALSA
HHHHHHHHHCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA