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The map label for this gene is lepB [H]

Identifier: 93005195

GI number: 93005195

Start: 443981

End: 444883

Strand: Direct

Name: lepB [H]

Synonym: Pcryo_0365

Alternate gene names: 93005195

Gene position: 443981-444883 (Clockwise)

Preceding gene: 93005194

Following gene: 93005196

Centisome position: 14.51

GC content: 42.64

Gene sequence:

>903_bases
ATGGATTTTGATTTCAATTTGATTTTAGTGCCATTAACCATAGGTTTGGGTATTATTTGGCTATTAGATAAGCTGACACT
GAAACAGCGTAAAACACGGGGTCGCGGTAAAGAGAGCTTGCTGGTACGCTGGGCATATGATTTTTTCCCCGTGCTGGCGG
TAGTATTAATTGTGCGCTCGTTTTTAATTGAGCCGTTTAATATTCCGTCGTCCTCGATGGTGCCAACGCTATATACGGGT
GACTTTATTGCCGTCAATAAGTATGCTTATGGTGTTCGTTTGCCACTGACTTATAATAAAGTAATCGATACTGGCACGCC
TGAACATGGCGATGTTGCCGTTTTTCGTTATCCAGAGAACCCAAGTATTTATTATATTAAGCGCGTCATTGGTCTGCCGG
GTGATACGGTTAGTTATAATCAAGGCACAATTGCGATTAATGACGTGCCTGTTGCTACTCAAGCCATTGATTTTGACCCC
AATGCAGAGCTGACGTCACAGTTATATTCGTCAGGGGAAGTTGCTCCGGGTCAAATGCTGACAGAAGAGAATGCTGCTGT
GATGGGTCAGCAAGAAGAAAGCGACGCAAAATATTTTAAAGAAACTCAAGGTAAGCATGAGTATGTTGTTCGTTATTTGA
ATGGTATGAACAGCTCGCAATATGCGCCATTTTTACAGCAACAGTCACCAGAAGTGGTGAGCTCAGAAGGCAATGAATGG
CGTATTAATGTGCCTGAAGGTCAATATTTTGTGATGGGCGATAACCGTGATCGCAGTGCAGATGGACGCTTTTGGGGCTT
TGTACCTGATGATAATTTAGCAGGAAAAGCAGTATATATTTGGATGCATAAGCCACCAGGTCTACAGCTACCTACTTTTA
AACGTAATGGTGCTATCGATTAA

Upstream 100 bases:

>100_bases
GCCGTATTGCAGGTAGATTAGATTATTAATAAATGAATCATCATTGCTGTTTTTACGGATGTCATCATTGGATAAGTAGC
TCGCTAATAGGCAATTAAGT

Downstream 100 bases:

>100_bases
TGACATCAATGTTCTATAGATATATTTACCGACAAACGTTTTGTGCTAATATTATGGCTATTCAATGCAATGATATTTAG
CTTATAAACATGCATTAAGA

Product: peptidase S26A, signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MDFDFNLILVPLTIGLGIIWLLDKLTLKQRKTRGRGKESLLVRWAYDFFPVLAVVLIVRSFLIEPFNIPSSSMVPTLYTG
DFIAVNKYAYGVRLPLTYNKVIDTGTPEHGDVAVFRYPENPSIYYIKRVIGLPGDTVSYNQGTIAINDVPVATQAIDFDP
NAELTSQLYSSGEVAPGQMLTEENAAVMGQQEESDAKYFKETQGKHEYVVRYLNGMNSSQYAPFLQQQSPEVVSSEGNEW
RINVPEGQYFVMGDNRDRSADGRFWGFVPDDNLAGKAVYIWMHKPPGLQLPTFKRNGAID

Sequences:

>Translated_300_residues
MDFDFNLILVPLTIGLGIIWLLDKLTLKQRKTRGRGKESLLVRWAYDFFPVLAVVLIVRSFLIEPFNIPSSSMVPTLYTG
DFIAVNKYAYGVRLPLTYNKVIDTGTPEHGDVAVFRYPENPSIYYIKRVIGLPGDTVSYNQGTIAINDVPVATQAIDFDP
NAELTSQLYSSGEVAPGQMLTEENAAVMGQQEESDAKYFKETQGKHEYVVRYLNGMNSSQYAPFLQQQSPEVVSSEGNEW
RINVPEGQYFVMGDNRDRSADGRFWGFVPDDNLAGKAVYIWMHKPPGLQLPTFKRNGAID
>Mature_300_residues
MDFDFNLILVPLTIGLGIIWLLDKLTLKQRKTRGRGKESLLVRWAYDFFPVLAVVLIVRSFLIEPFNIPSSSMVPTLYTG
DFIAVNKYAYGVRLPLTYNKVIDTGTPEHGDVAVFRYPENPSIYYIKRVIGLPGDTVSYNQGTIAINDVPVATQAIDFDP
NAELTSQLYSSGEVAPGQMLTEENAAVMGQQEESDAKYFKETQGKHEYVVRYLNGMNSSQYAPFLQQQSPEVVSSEGNEW
RINVPEGQYFVMGDNRDRSADGRFWGFVPDDNLAGKAVYIWMHKPPGLQLPTFKRNGAID

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=315, Percent_Identity=37.4603174603175, Blast_Score=181, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 33739; Mature: 33739

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFDFNLILVPLTIGLGIIWLLDKLTLKQRKTRGRGKESLLVRWAYDFFPVLAVVLIVRS
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHH
FLIEPFNIPSSSMVPTLYTGDFIAVNKYAYGVRLPLTYNKVIDTGTPEHGDVAVFRYPEN
HHCCCCCCCCCCCCCEEECCCEEEEEEEEEEEEECEEEHHHCCCCCCCCCCEEEEEECCC
PSIYYIKRVIGLPGDTVSYNQGTIAINDVPVATQAIDFDPNAELTSQLYSSGEVAPGQML
CCEEEEEEECCCCCCCEECCCCEEEECCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCEE
TEENAAVMGQQEESDAKYFKETQGKHEYVVRYLNGMNSSQYAPFLQQQSPEVVSSEGNEW
ECCCHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCHHHCCCCEE
RINVPEGQYFVMGDNRDRSADGRFWGFVPDDNLAGKAVYIWMHKPPGLQLPTFKRNGAID
EEECCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDFDFNLILVPLTIGLGIIWLLDKLTLKQRKTRGRGKESLLVRWAYDFFPVLAVVLIVRS
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHH
FLIEPFNIPSSSMVPTLYTGDFIAVNKYAYGVRLPLTYNKVIDTGTPEHGDVAVFRYPEN
HHCCCCCCCCCCCCCEEECCCEEEEEEEEEEEEECEEEHHHCCCCCCCCCCEEEEEECCC
PSIYYIKRVIGLPGDTVSYNQGTIAINDVPVATQAIDFDPNAELTSQLYSSGEVAPGQML
CCEEEEEEECCCCCCCEECCCCEEEECCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCEE
TEENAAVMGQQEESDAKYFKETQGKHEYVVRYLNGMNSSQYAPFLQQQSPEVVSSEGNEW
ECCCHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCHHHCCCCEE
RINVPEGQYFVMGDNRDRSADGRFWGFVPDDNLAGKAVYIWMHKPPGLQLPTFKRNGAID
EEECCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]