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The map label for this gene is bioD [H]

Identifier: 93005193

GI number: 93005193

Start: 440295

End: 441014

Strand: Direct

Name: bioD [H]

Synonym: Pcryo_0362

Alternate gene names: 93005193

Gene position: 440295-441014 (Clockwise)

Preceding gene: 93005192

Following gene: 93005194

Centisome position: 14.39

GC content: 41.67

Gene sequence:

>720_bases
ATGAGCGTGCTCTTTATATCTGGTATCGATACCGACATTGGCAAAACTTATGCTACCGGTATGATTGCCAAAGCGCTGAT
GCAGCACGGTGTTAATGTTATTACTCAAAAGCTGGTGCAAACGGGCGTCGCAAGAGATTTAATTAGCGGAAAAATAGGAA
TTGCTGACGATATTATTACCCATCGTCAGCTGATGGGCATTCCGCTACAGCCGTGTGATATTGATAATACCACTTGCCCG
TATCGTTATGAGAAACCTGCGTCACCGCATTTATCCGCCGCACTTGCTAATGATATTCTTAATACTGATGTGATTACAAG
CGTTACAAAAATTCTGCAAGCGGATTATGAGGTAGTGCTTTTAGAAGGGGCAGGTGGCTTATTAGTGCCCATCACTGAGC
AATTATTAACCTTAGATTATATTGCTGAGCAAGGTTATCCCCTTATTCTGGTCACATCAGGTCGGCTTGGCAGCATCAAC
CATACGTTGCTAAGTTTAGAAGCCATAAAATCTCGTGGTCTAGACGTTCATAGCGTTATTTATAATCATATTCACGACAA
TGCTGCTCAGACGGATGAACAGATAGCCGCTAGTACGATAAAATTTTTGCAAAACTACTTAGCTGAGTATCATCCAACGG
CGCATTGGTTAGCCTTACCTGTACAAGAGGATAATGGGTTTAGTCATACAGATTTTATACTCCCTCAAAACTTTGTATAA

Upstream 100 bases:

>100_bases
ATATTATGCCGCCCTATGTGATTACCGATGATGAACTTACCACTCTTTGCCAAGCGTTATTAAAAGTGGTCAGTAGTTAT
TTAACGCGAAAGGATTAATG

Downstream 100 bases:

>100_bases
ATCACCGCTAAAAATAAGCCAAAAAAAATCTCCGAAAGCAATATGAATTTTGCTATAATAGCGCGCTTGGTAGACTAGGC
AATCGCCGCTGCACACTGGC

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSVLFISGIDTDIGKTYATGMIAKALMQHGVNVITQKLVQTGVARDLISGKIGIADDIITHRQLMGIPLQPCDIDNTTCP
YRYEKPASPHLSAALANDILNTDVITSVTKILQADYEVVLLEGAGGLLVPITEQLLTLDYIAEQGYPLILVTSGRLGSIN
HTLLSLEAIKSRGLDVHSVIYNHIHDNAAQTDEQIAASTIKFLQNYLAEYHPTAHWLALPVQEDNGFSHTDFILPQNFV

Sequences:

>Translated_239_residues
MSVLFISGIDTDIGKTYATGMIAKALMQHGVNVITQKLVQTGVARDLISGKIGIADDIITHRQLMGIPLQPCDIDNTTCP
YRYEKPASPHLSAALANDILNTDVITSVTKILQADYEVVLLEGAGGLLVPITEQLLTLDYIAEQGYPLILVTSGRLGSIN
HTLLSLEAIKSRGLDVHSVIYNHIHDNAAQTDEQIAASTIKFLQNYLAEYHPTAHWLALPVQEDNGFSHTDFILPQNFV
>Mature_238_residues
SVLFISGIDTDIGKTYATGMIAKALMQHGVNVITQKLVQTGVARDLISGKIGIADDIITHRQLMGIPLQPCDIDNTTCPY
RYEKPASPHLSAALANDILNTDVITSVTKILQADYEVVLLEGAGGLLVPITEQLLTLDYIAEQGYPLILVTSGRLGSINH
TLLSLEAIKSRGLDVHSVIYNHIHDNAAQTDEQIAASTIKFLQNYLAEYHPTAHWLALPVQEDNGFSHTDFILPQNFV

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=181, Percent_Identity=27.0718232044199, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 26084; Mature: 25953

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLFISGIDTDIGKTYATGMIAKALMQHGVNVITQKLVQTGVARDLISGKIGIADDIIT
CEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
HRQLMGIPLQPCDIDNTTCPYRYEKPASPHLSAALANDILNTDVITSVTKILQADYEVVL
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LEGAGGLLVPITEQLLTLDYIAEQGYPLILVTSGRLGSINHTLLSLEAIKSRGLDVHSVI
EECCCCEEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHH
YNHIHDNAAQTDEQIAASTIKFLQNYLAEYHPTAHWLALPVQEDNGFSHTDFILPQNFV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEECCCCCCC
>Mature Secondary Structure 
SVLFISGIDTDIGKTYATGMIAKALMQHGVNVITQKLVQTGVARDLISGKIGIADDIIT
EEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
HRQLMGIPLQPCDIDNTTCPYRYEKPASPHLSAALANDILNTDVITSVTKILQADYEVVL
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LEGAGGLLVPITEQLLTLDYIAEQGYPLILVTSGRLGSINHTLLSLEAIKSRGLDVHSVI
EECCCCEEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHH
YNHIHDNAAQTDEQIAASTIKFLQNYLAEYHPTAHWLALPVQEDNGFSHTDFILPQNFV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]