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The map label for this gene is fur [H]

Identifier: 93005122

GI number: 93005122

Start: 349425

End: 349859

Strand: Direct

Name: fur [H]

Synonym: Pcryo_0291

Alternate gene names: 93005122

Gene position: 349425-349859 (Clockwise)

Preceding gene: 93005120

Following gene: 93005125

Centisome position: 11.42

GC content: 42.99

Gene sequence:

>435_bases
ATGGCTTCTTTTACCAATCAAGACTTACGTAGAGCGGGTCTAAAAGTAACGTTACCGCGTATCAAAATTCTAGAGCTGCT
TGAGAGTGCAAAGCTGCATCATATGAGCGCAGAGGAGGTTTACAAGGCGCTAATTGAGCAAGGCGAGGATGTAGGTTTAG
CGACCGTTTATCGCGTGCTGACTCAGTTTGAGCAGGCAGGTATTGTCGAGCGTCACAACTTTGAAAACAATTTATCCGTG
TTTGAGATTACTCAAGAAGAGCATCACGACCATCTGGTTTGTGATAATTGCGGTAAGATTGTCGAATTTCATAATGAAGT
GATTGAAGAAGAACAGCTTAAAGTAGCAGCAGAGCATGGCTTTAAGTTATCAGGTCACTCATTGGTACTATATGGTATCT
GTGATGACCAAGCCTGTAAGGACAGCGTCAAGTAA

Upstream 100 bases:

>100_bases
GGATGATTTTTTGCAATTACCCATTCATCACTACTGATGATTATTTACCTTATGTTTTTTGAACTTATTTGCTAAGACTT
TCATAGTCAGAAGGGATATT

Downstream 100 bases:

>100_bases
GCATCAACTTATCGATGAGATAAAATTAAAAAAGCCCTTATATATGATGAGGGCTTTTTTATAACGGTTTCTTAGGCATA
AAAAATAATAACTATGGTTA

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MASFTNQDLRRAGLKVTLPRIKILELLESAKLHHMSAEEVYKALIEQGEDVGLATVYRVLTQFEQAGIVERHNFENNLSV
FEITQEEHHDHLVCDNCGKIVEFHNEVIEEEQLKVAAEHGFKLSGHSLVLYGICDDQACKDSVK

Sequences:

>Translated_144_residues
MASFTNQDLRRAGLKVTLPRIKILELLESAKLHHMSAEEVYKALIEQGEDVGLATVYRVLTQFEQAGIVERHNFENNLSV
FEITQEEHHDHLVCDNCGKIVEFHNEVIEEEQLKVAAEHGFKLSGHSLVLYGICDDQACKDSVK
>Mature_143_residues
ASFTNQDLRRAGLKVTLPRIKILELLESAKLHHMSAEEVYKALIEQGEDVGLATVYRVLTQFEQAGIVERHNFENNLSVF
EITQEEHHDHLVCDNCGKIVEFHNEVIEEEQLKVAAEHGFKLSGHSLVLYGICDDQACKDSVK

Specific function: Fur acts as a repressor, employing Fe(2+) as a cofactor to bind the operator of the iron transport operon [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=138, Percent_Identity=57.9710144927536, Blast_Score=176, Evalue=7e-46,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16330; Mature: 16198

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASFTNQDLRRAGLKVTLPRIKILELLESAKLHHMSAEEVYKALIEQGEDVGLATVYRVL
CCCCCCHHHHHCCCEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHH
TQFEQAGIVERHNFENNLSVFEITQEEHHDHLVCDNCGKIVEFHNEVIEEEQLKVAAEHG
HHHHHCCCHHHCCCCCCCEEEEEEHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCC
FKLSGHSLVLYGICDDQACKDSVK
EEECCCCEEEEECCCCHHHHCCCC
>Mature Secondary Structure 
ASFTNQDLRRAGLKVTLPRIKILELLESAKLHHMSAEEVYKALIEQGEDVGLATVYRVL
CCCCCHHHHHCCCEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHH
TQFEQAGIVERHNFENNLSVFEITQEEHHDHLVCDNCGKIVEFHNEVIEEEQLKVAAEHG
HHHHHCCCHHHCCCCCCCEEEEEEHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCC
FKLSGHSLVLYGICDDQACKDSVK
EEECCCCEEEEECCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406286; 11586360; 12142430 [H]