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The map label for this gene is potC [H]

Identifier: 93005068

GI number: 93005068

Start: 279424

End: 280254

Strand: Reverse

Name: potC [H]

Synonym: Pcryo_0237

Alternate gene names: 93005068

Gene position: 280254-279424 (Counterclockwise)

Preceding gene: 93005069

Following gene: 93005067

Centisome position: 9.16

GC content: 43.44

Gene sequence:

>831_bases
ATGTCTGATAGTTCACTAAATGGCTCAACAAATAACAAATCGCCGAAAAACAAAAATCCCATAAGGTTTGGCAATATCGT
CGCCAAAGGCTACCTTGGGCTGATTTATACTTTATTATATCTACCCATCATAGTATTGGTAGTGATGTCATTTAATAAGT
CAAAAATTGGCTATAATTGGGGCGGCTTTAGTTTAAAGTGGTATGAGTCATTACTCAATAATCAGGCGATGTTAGATGCT
TTTTGGCATTCGATTTTATTAGGTTTGGTTGCCGCTACAGTCTCAACCATCATCGGTACACTGACCGCACTGGCGTTACA
TCGCTATGACTTTCGTGGTAAAGGGCTGCTAAATGGCTTGTTATTTGTGCTAATGATGTCGCCTGAGATTGTCTTAGCGA
TATCGCTCCTGGCACTGTTTTTATTAATTGGGCTACAGCTGGGTTTTGTCTCGCTATTATTGGCGCACATTACGTTTTGC
TTGCCGTTTGTCGTTATAACTGTCTTTGCGCGCTTAAGTAGTTTGGATGAGCGTTTAATGGAAGCGGCGCGAGATTTGGG
TGCTAGCGAATCAACAATGGTACGGACAGTATTGATTCCGGTGATTTTCCCTGCGGTGATGGCAGGTTGGCTCCTTGCTT
TTACCTTATCGCTCGATGATGTGGTGGTATCGACCTTTGTCACCGGTCCTAGCTATGAGATATTGCCGCTACGTATTTAT
TCTATGGTACGTGTGGGTCTTAAACCCGAGGTCAATGCCATTGGGACGATTTTACTCGTCGCTTCGTTAATTTTGGTGGT
TATCTCGCAATTGCTCCTACGTCGGCGCTGA

Upstream 100 bases:

>100_bases
CCGCCAGTGTGCTATTGACGCTTGCTATGGCGGTATTATTGCTTGCCTATCGCGCTAGTAGTCGCCGTATCGGCAAGACT
GACTTTAGCGAGGTGGCCTA

Downstream 100 bases:

>100_bases
TGTTAATTTTACTTTAATAACAGCTTTAACATCATATTAGATAAAAAGTTTTTAACAATTTTTCAGCCTTTATTTTTAGG
CCTTTATAAGTCGCAACTTT

Product: spermidine/putrescine ABC transporter membrane protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MSDSSLNGSTNNKSPKNKNPIRFGNIVAKGYLGLIYTLLYLPIIVLVVMSFNKSKIGYNWGGFSLKWYESLLNNQAMLDA
FWHSILLGLVAATVSTIIGTLTALALHRYDFRGKGLLNGLLFVLMMSPEIVLAISLLALFLLIGLQLGFVSLLLAHITFC
LPFVVITVFARLSSLDERLMEAARDLGASESTMVRTVLIPVIFPAVMAGWLLAFTLSLDDVVVSTFVTGPSYEILPLRIY
SMVRVGLKPEVNAIGTILLVASLILVVISQLLLRRR

Sequences:

>Translated_276_residues
MSDSSLNGSTNNKSPKNKNPIRFGNIVAKGYLGLIYTLLYLPIIVLVVMSFNKSKIGYNWGGFSLKWYESLLNNQAMLDA
FWHSILLGLVAATVSTIIGTLTALALHRYDFRGKGLLNGLLFVLMMSPEIVLAISLLALFLLIGLQLGFVSLLLAHITFC
LPFVVITVFARLSSLDERLMEAARDLGASESTMVRTVLIPVIFPAVMAGWLLAFTLSLDDVVVSTFVTGPSYEILPLRIY
SMVRVGLKPEVNAIGTILLVASLILVVISQLLLRRR
>Mature_275_residues
SDSSLNGSTNNKSPKNKNPIRFGNIVAKGYLGLIYTLLYLPIIVLVVMSFNKSKIGYNWGGFSLKWYESLLNNQAMLDAF
WHSILLGLVAATVSTIIGTLTALALHRYDFRGKGLLNGLLFVLMMSPEIVLAISLLALFLLIGLQLGFVSLLLAHITFCL
PFVVITVFARLSSLDERLMEAARDLGASESTMVRTVLIPVIFPAVMAGWLLAFTLSLDDVVVSTFVTGPSYEILPLRIYS
MVRVGLKPEVNAIGTILLVASLILVVISQLLLRRR

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=253, Percent_Identity=60.4743083003953, Blast_Score=310, Evalue=6e-86,
Organism=Escherichia coli, GI1787081, Length=250, Percent_Identity=40, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI1787714, Length=202, Percent_Identity=34.6534653465347, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788764, Length=206, Percent_Identity=27.6699029126214, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30291; Mature: 30160

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDSSLNGSTNNKSPKNKNPIRFGNIVAKGYLGLIYTLLYLPIIVLVVMSFNKSKIGYNW
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GGFSLKWYESLLNNQAMLDAFWHSILLGLVAATVSTIIGTLTALALHRYDFRGKGLLNGL
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LFVLMMSPEIVLAISLLALFLLIGLQLGFVSLLLAHITFCLPFVVITVFARLSSLDERLM
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAARDLGASESTMVRTVLIPVIFPAVMAGWLLAFTLSLDDVVVSTFVTGPSYEILPLRIY
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
SMVRVGLKPEVNAIGTILLVASLILVVISQLLLRRR
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]