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The map label for this gene is trpB1 [H]

Identifier: 93005029

GI number: 93005029

Start: 233837

End: 235063

Strand: Direct

Name: trpB1 [H]

Synonym: Pcryo_0198

Alternate gene names: 93005029

Gene position: 233837-235063 (Clockwise)

Preceding gene: 93005027

Following gene: 93005030

Centisome position: 7.64

GC content: 47.19

Gene sequence:

>1227_bases
ATGACAACGCAAAATACCGCCACTGGCTACGGTTTACATCAATCAATTTTGCCCAATGACGATGGTCTATATGGTGAGTT
CGGTGGCAAAATCGGTCATCCTGAGCTTGCCAAAGCCATGGCAGAAATCGAAGTGGGCTTTCGTGAAATCATTAAAAATG
ACGATTTTATCGCTGAGATGAAGCGCTTGCGTGAGACCTATGTTGGTCGTCCAAGTCCTATTTATCATGCACAGCGTTTG
ACCGAGCATTGCGGAGGCGCGCAGATTTATTTTAAGCGTGAAGATTTAAATCATACGGGTGCGCATAAGATTAATCACTG
TTTGGGTGAAGTATTATTAGCCAAGAAATTAGGCAAAACCAAAGTGATTGCCGAAACGGGCGCGGGGCAACATGGCGTAG
CATTGGCAACGGCAGCGGCATTGATGGGCTTGGAATGTGAGATTCACATGGGTGTGGTCGATATTAAAAAAGAGCATCCA
AACGTCAGTCGTATGAAGATTTTGGGTGCCAATATCGTGCCAGTCTCGCGCGGTGCTGGTACGCTAAAAGAAGCGGTTGA
TAGTGCTTTTGAGACTTATTTGGATGAGCTTGATAGCAGTATGTTCGCGATTGGCTCGGCACTGGGACCTGCGCCCTACC
CTGAAATGGTCAGCTATTTTCAGTCAGTGGTTGGTCATGAAGCGCGGGCGCAGTTCTTAGCGACGACGGGTAAGCTACCT
AATAAAGTGGTTGCTTGTATTGGCGGCGGCTCTAATGCTATCGGTATGTTTAGCGGCTTTTTTGATGATAAAGATGTAGA
AAAAATAGGCGTGGAACCCGCAGGCGAAGGTCTGGATACTCCTAATCATGCGGCGACAATGTCGCTCGGCGTGAAAGGTG
AGATTCATGGTTTTAAATGCTATGTGCTGCTCGATGAAAAAGGCGAGCCAGCTCCCGTACATTCGATTGCCTCCGGTCTT
GATTATCCTGGGGTTGGACCACAGCACTCACATCTGCGAGATTTAAAACTGGCCACTTATGAGTCGGCGACTGATGCTGA
ATGTCTAGAAGCGTTTATGGCATTGTCGCGCCTTGAGGGTATTATTCCTGCTTTAGAGTCGGCACATGCCATCGCTTATG
CGATGAAAATCGCCAAGGATATGTCAGCGGATGAGACGATTTTGGTCAATTTGTCAGGGCGTGGCGATAAAGACATCGAT
TTTATTTTGGACAAGGTGGATTTATAA

Upstream 100 bases:

>100_bases
GAACGTAAATACATATAAAATATTTTTATCATCAAAAATGCTAAATAATTTGGCAAAAATATTAATGCTAATACTCATTT
TAAAATAATAAGGCTTAACT

Downstream 100 bases:

>100_bases
AATAAATCTGTGATAAGTACAGAAAATACAATACCTATTGAGCGCTGAACCAGTTATCATCGAGGTTTTTTTACTGTCTA
ATGCTCGATAGGATCATCTC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MTTQNTATGYGLHQSILPNDDGLYGEFGGKIGHPELAKAMAEIEVGFREIIKNDDFIAEMKRLRETYVGRPSPIYHAQRL
TEHCGGAQIYFKREDLNHTGAHKINHCLGEVLLAKKLGKTKVIAETGAGQHGVALATAAALMGLECEIHMGVVDIKKEHP
NVSRMKILGANIVPVSRGAGTLKEAVDSAFETYLDELDSSMFAIGSALGPAPYPEMVSYFQSVVGHEARAQFLATTGKLP
NKVVACIGGGSNAIGMFSGFFDDKDVEKIGVEPAGEGLDTPNHAATMSLGVKGEIHGFKCYVLLDEKGEPAPVHSIASGL
DYPGVGPQHSHLRDLKLATYESATDAECLEAFMALSRLEGIIPALESAHAIAYAMKIAKDMSADETILVNLSGRGDKDID
FILDKVDL

Sequences:

>Translated_408_residues
MTTQNTATGYGLHQSILPNDDGLYGEFGGKIGHPELAKAMAEIEVGFREIIKNDDFIAEMKRLRETYVGRPSPIYHAQRL
TEHCGGAQIYFKREDLNHTGAHKINHCLGEVLLAKKLGKTKVIAETGAGQHGVALATAAALMGLECEIHMGVVDIKKEHP
NVSRMKILGANIVPVSRGAGTLKEAVDSAFETYLDELDSSMFAIGSALGPAPYPEMVSYFQSVVGHEARAQFLATTGKLP
NKVVACIGGGSNAIGMFSGFFDDKDVEKIGVEPAGEGLDTPNHAATMSLGVKGEIHGFKCYVLLDEKGEPAPVHSIASGL
DYPGVGPQHSHLRDLKLATYESATDAECLEAFMALSRLEGIIPALESAHAIAYAMKIAKDMSADETILVNLSGRGDKDID
FILDKVDL
>Mature_407_residues
TTQNTATGYGLHQSILPNDDGLYGEFGGKIGHPELAKAMAEIEVGFREIIKNDDFIAEMKRLRETYVGRPSPIYHAQRLT
EHCGGAQIYFKREDLNHTGAHKINHCLGEVLLAKKLGKTKVIAETGAGQHGVALATAAALMGLECEIHMGVVDIKKEHPN
VSRMKILGANIVPVSRGAGTLKEAVDSAFETYLDELDSSMFAIGSALGPAPYPEMVSYFQSVVGHEARAQFLATTGKLPN
KVVACIGGGSNAIGMFSGFFDDKDVEKIGVEPAGEGLDTPNHAATMSLGVKGEIHGFKCYVLLDEKGEPAPVHSIASGLD
YPGVGPQHSHLRDLKLATYESATDAECLEAFMALSRLEGIIPALESAHAIAYAMKIAKDMSADETILVNLSGRGDKDIDF
ILDKVDL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=382, Percent_Identity=46.5968586387435, Blast_Score=350, Evalue=7e-98,
Organism=Saccharomyces cerevisiae, GI6321412, Length=380, Percent_Identity=50.7894736842105, Blast_Score=399, Evalue=1e-112,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43675; Mature: 43544

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQNTATGYGLHQSILPNDDGLYGEFGGKIGHPELAKAMAEIEVGFREIIKNDDFIAEM
CCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
KRLRETYVGRPSPIYHAQRLTEHCGGAQIYFKREDLNHTGAHKINHCLGEVLLAKKLGKT
HHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
KVIAETGAGQHGVALATAAALMGLECEIHMGVVDIKKEHPNVSRMKILGANIVPVSRGAG
EEEEECCCCCCCHHHHHHHHHHCCCEEEEECEEEEECCCCCHHHEEEECCCEEECCCCCH
TLKEAVDSAFETYLDELDSSMFAIGSALGPAPYPEMVSYFQSVVGHEARAQFLATTGKLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCC
NKVVACIGGGSNAIGMFSGFFDDKDVEKIGVEPAGEGLDTPNHAATMSLGVKGEIHGFKC
CEEEEEECCCCCCHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCEEECCEEE
YVLLDEKGEPAPVHSIASGLDYPGVGPQHSHLRDLKLATYESATDAECLEAFMALSRLEG
EEEECCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
IIPALESAHAIAYAMKIAKDMSADETILVNLSGRGDKDIDFILDKVDL
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
TTQNTATGYGLHQSILPNDDGLYGEFGGKIGHPELAKAMAEIEVGFREIIKNDDFIAEM
CCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
KRLRETYVGRPSPIYHAQRLTEHCGGAQIYFKREDLNHTGAHKINHCLGEVLLAKKLGKT
HHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
KVIAETGAGQHGVALATAAALMGLECEIHMGVVDIKKEHPNVSRMKILGANIVPVSRGAG
EEEEECCCCCCCHHHHHHHHHHCCCEEEEECEEEEECCCCCHHHEEEECCCEEECCCCCH
TLKEAVDSAFETYLDELDSSMFAIGSALGPAPYPEMVSYFQSVVGHEARAQFLATTGKLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCC
NKVVACIGGGSNAIGMFSGFFDDKDVEKIGVEPAGEGLDTPNHAATMSLGVKGEIHGFKC
CEEEEEECCCCCCHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCEEECCEEE
YVLLDEKGEPAPVHSIASGLDYPGVGPQHSHLRDLKLATYESATDAECLEAFMALSRLEG
EEEECCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
IIPALESAHAIAYAMKIAKDMSADETILVNLSGRGDKDIDFILDKVDL
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500908 [H]