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The map label for this gene is yciK [H]

Identifier: 93004963

GI number: 93004963

Start: 154923

End: 155798

Strand: Direct

Name: yciK [H]

Synonym: Pcryo_0132

Alternate gene names: 93004963

Gene position: 154923-155798 (Clockwise)

Preceding gene: 93004962

Following gene: 93004964

Centisome position: 5.06

GC content: 45.66

Gene sequence:

>876_bases
ATGAGTGACAATATCAACCCATTAGCGAATCAGTCGGCAAACCATCCAGCCGACAATATAGCCAATAATATTGCAAGCCA
GCAGACTGAATTGCAATCGTCTGCAACCGAATTAACCCACGGGAATATTCGTGACTTTGTACCCTCTGAAAACTGCTTAG
ATGGCAAGACCATTTTAGTCACAGGCGCAGGTGATGGCATTGGTCGGGTCGCTGCATTGACCTATGCACGCTATGGCGCA
ACGGTGCTGCTATTAGGACGTACCAGTAGCAAGCTTGAATATGTTTATGATGAAATCGAGAGCTTTGGTGGTAAGCAACC
TGCTATGTTACCGATGAATCTAGAAGGGGCGACTTATGCAGAAATGCAAAAGCTAGAAAATTTGATTCATAGAGAAGTTG
GTCAGCTAGATGGGATATTGCATAATGCTGGGATGCTTGGTCCATTGACGCCACTTGAGATGTACGATGTAGATATGTTT
GCTCAAGTCATGAAGATTAACTTCACAGCGACCTTTATGCTTACCCAAGCGCTACTGCCGTTACTCAAAGATGCACCGCA
TGGTTCTATCGTATTTACATCTAGCAGCGTTGGTACGCATCCTCGCGCATTTTGGGGTGCTTACGCGCTGTCTAAGCAAG
CGGTAGAAGGAATGAGCGATATCTTTACCCAAGAGACGCAAAACACCACCAATCTGCGTTTTAACTGTATCAATCCGGGT
GGTACTCGCACCAATATGCGTGCTCACGCTTATCCAGGTGAAAATCCGATGAGTCTGAAAACTCCTGAAGATATTATGGC
AGGTTATGTGTGCTTGATGAGTGATGAGAGTATCGGGGTACGTGGACAAGTGGTTGAGTTACAACCCAAGGATTGA

Upstream 100 bases:

>100_bases
CAAATGAGCCACAAGATCAGCGTGTTATCAGGCAATATTTAACAACATAGCATAATGGTTAACCATACCATTTATTAAAC
GATAAGTAGTGAGTAACGCC

Downstream 100 bases:

>100_bases
GCGACAATTTGTCTGCGCAGGTAGATTGAAATTGCTGATATTTAACCCCATCTATTTGTTATCAAAGACATTTATGCTCG
ATTAAAGATACGCATAATGA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSDNINPLANQSANHPADNIANNIASQQTELQSSATELTHGNIRDFVPSENCLDGKTILVTGAGDGIGRVAALTYARYGA
TVLLLGRTSSKLEYVYDEIESFGGKQPAMLPMNLEGATYAEMQKLENLIHREVGQLDGILHNAGMLGPLTPLEMYDVDMF
AQVMKINFTATFMLTQALLPLLKDAPHGSIVFTSSSVGTHPRAFWGAYALSKQAVEGMSDIFTQETQNTTNLRFNCINPG
GTRTNMRAHAYPGENPMSLKTPEDIMAGYVCLMSDESIGVRGQVVELQPKD

Sequences:

>Translated_291_residues
MSDNINPLANQSANHPADNIANNIASQQTELQSSATELTHGNIRDFVPSENCLDGKTILVTGAGDGIGRVAALTYARYGA
TVLLLGRTSSKLEYVYDEIESFGGKQPAMLPMNLEGATYAEMQKLENLIHREVGQLDGILHNAGMLGPLTPLEMYDVDMF
AQVMKINFTATFMLTQALLPLLKDAPHGSIVFTSSSVGTHPRAFWGAYALSKQAVEGMSDIFTQETQNTTNLRFNCINPG
GTRTNMRAHAYPGENPMSLKTPEDIMAGYVCLMSDESIGVRGQVVELQPKD
>Mature_290_residues
SDNINPLANQSANHPADNIANNIASQQTELQSSATELTHGNIRDFVPSENCLDGKTILVTGAGDGIGRVAALTYARYGAT
VLLLGRTSSKLEYVYDEIESFGGKQPAMLPMNLEGATYAEMQKLENLIHREVGQLDGILHNAGMLGPLTPLEMYDVDMFA
QVMKINFTATFMLTQALLPLLKDAPHGSIVFTSSSVGTHPRAFWGAYALSKQAVEGMSDIFTQETQNTTNLRFNCINPGG
TRTNMRAHAYPGENPMSLKTPEDIMAGYVCLMSDESIGVRGQVVELQPKD

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI25282469, Length=202, Percent_Identity=30.1980198019802, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4504505, Length=201, Percent_Identity=28.3582089552239, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI210032110, Length=200, Percent_Identity=26.5, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4557649, Length=196, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI142976729, Length=212, Percent_Identity=25.4716981132075, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI4503817, Length=184, Percent_Identity=28.2608695652174, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI32455239, Length=201, Percent_Identity=30.8457711442786, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI5031765, Length=201, Percent_Identity=30.8457711442786, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI20149619, Length=212, Percent_Identity=28.3018867924528, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI19743808, Length=207, Percent_Identity=28.5024154589372, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI7706318, Length=207, Percent_Identity=26.0869565217391, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1787526, Length=244, Percent_Identity=51.6393442622951, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI87082100, Length=217, Percent_Identity=32.258064516129, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789378, Length=267, Percent_Identity=28.8389513108614, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=26.5060240963855, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=25.5144032921811, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786701, Length=209, Percent_Identity=30.622009569378, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790717, Length=194, Percent_Identity=26.8041237113402, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=200, Percent_Identity=30.5, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=238, Percent_Identity=30.672268907563, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=201, Percent_Identity=32.8358208955224, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=204, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=217, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=201, Percent_Identity=30.3482587064677, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71997402, Length=178, Percent_Identity=30.8988764044944, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=185, Percent_Identity=27.5675675675676, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=171, Percent_Identity=27.4853801169591, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=189, Percent_Identity=25.3968253968254, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=205, Percent_Identity=30.7317073170732, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=204, Percent_Identity=28.4313725490196, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=207, Percent_Identity=29.951690821256, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25152911, Length=178, Percent_Identity=31.4606741573034, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17570069, Length=180, Percent_Identity=28.3333333333333, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=204, Percent_Identity=29.9019607843137, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=201, Percent_Identity=31.8407960199005, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322861, Length=252, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322226, Length=211, Percent_Identity=26.5402843601896, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24644339, Length=197, Percent_Identity=34.010152284264, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21358495, Length=210, Percent_Identity=30, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI23397609, Length=195, Percent_Identity=32.8205128205128, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571526, Length=193, Percent_Identity=32.6424870466321, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355319, Length=241, Percent_Identity=26.1410788381743, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24643142, Length=203, Percent_Identity=31.5270935960591, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24640492, Length=227, Percent_Identity=27.7533039647577, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21357041, Length=195, Percent_Identity=29.7435897435897, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=29.2, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI18859837, Length=195, Percent_Identity=30.2564102564103, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24584744, Length=199, Percent_Identity=30.6532663316583, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28574402, Length=199, Percent_Identity=30.6532663316583, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31576; Mature: 31445

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNINPLANQSANHPADNIANNIASQQTELQSSATELTHGNIRDFVPSENCLDGKTILV
CCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEEE
TGAGDGIGRVAALTYARYGATVLLLGRTSSKLEYVYDEIESFGGKQPAMLPMNLEGATYA
EECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCCHHH
EMQKLENLIHREVGQLDGILHNAGMLGPLTPLEMYDVDMFAQVMKINFTATFMLTQALLP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LLKDAPHGSIVFTSSSVGTHPRAFWGAYALSKQAVEGMSDIFTQETQNTTNLRFNCINPG
HHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
GTRTNMRAHAYPGENPMSLKTPEDIMAGYVCLMSDESIGVRGQVVELQPKD
CCCCCCEEECCCCCCCCCCCCHHHHHHCEEEEECCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
SDNINPLANQSANHPADNIANNIASQQTELQSSATELTHGNIRDFVPSENCLDGKTILV
CCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEEE
TGAGDGIGRVAALTYARYGATVLLLGRTSSKLEYVYDEIESFGGKQPAMLPMNLEGATYA
EECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCCHHH
EMQKLENLIHREVGQLDGILHNAGMLGPLTPLEMYDVDMFAQVMKINFTATFMLTQALLP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LLKDAPHGSIVFTSSSVGTHPRAFWGAYALSKQAVEGMSDIFTQETQNTTNLRFNCINPG
HHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
GTRTNMRAHAYPGENPMSLKTPEDIMAGYVCLMSDESIGVRGQVVELQPKD
CCCCCCEEECCCCCCCCCCCCHHHHHHCEEEEECCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]