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The map label for this gene is sdhB [H]

Identifier: 93004941

GI number: 93004941

Start: 127538

End: 128248

Strand: Direct

Name: sdhB [H]

Synonym: Pcryo_0110

Alternate gene names: 93004941

Gene position: 127538-128248 (Clockwise)

Preceding gene: 93004940

Following gene: 93004942

Centisome position: 4.17

GC content: 45.85

Gene sequence:

>711_bases
ATGAGCCGAGGTACTCGCACCATCGAAATCTATCGCTACGATCCTGATCTGGACGCAGCGCCGCGTATGCAAACTTATAC
GATTGAGCTACTAGACTCAGATCGTATGTTGCTTGACGTGTTATTACGCCTAAAGAAGGAAGATGAAACTCTTACCTTCC
GTCGCTCGTGCCGTGAAGGCATCTGTGGCTCTGATGGCATGAATATTAATGGTAAAAATGGTCTAGCATGTTTGATCAAC
ATGAATACTTTGCCAGAAAAAGTAACCGTTCGCCCGTTACCAGGTTTGCCAGTGGTTCGTGATTTGGTCGTCGATATGAA
CCAATTCTACGAGCAGTACGAAAAAGTACATCCATTCTTAATTAATGATCAGCCAGCGCCTGCGACTGAGCGCTTGCAGT
CGCCTGAGCAACGTGACAAGTTAAATGGTTTATATGAATGTATCTTATGTGCCTGCTGTTCAACCAGCTGCCCATCATTC
TGGTGGAATCCTGATAAGTTCTTAGGACCATCAGCACTACTGCATGCTGATCGTTTTGTTTCTGACAGCCGTGATAGTGA
TACGCGCGCGCGTCTGGCTCGTTTAGACGATCCATTCAGCTTATTTCGTTGCCGCGGTATCATGAACTGCGTATCAGTAT
GTCCAAAAGGCTTGAATCCAACCAAAGCTATCGGTCATCTGCGTAATTTGTTGCTTGATCAAGCAGGTTAA

Upstream 100 bases:

>100_bases
ATCAGTATTTGATCATTCTTGTCAGTACAGATTAATAGCCAGCGCGACTATGTTGCAATCCTTGTATGCCCGCCATCACC
GACGTGTGGAGTTTAGCATT

Downstream 100 bases:

>100_bases
TATACCTTTTAGCCTCAATTAGCTTTATAATAGCGCTATAAAAAACACCACCTGAGATAAGGTGGTGTTTTTTATTCGTT
AAAATAAGCAAAACAATAGC

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSRGTRTIEIYRYDPDLDAAPRMQTYTIELLDSDRMLLDVLLRLKKEDETLTFRRSCREGICGSDGMNINGKNGLACLIN
MNTLPEKVTVRPLPGLPVVRDLVVDMNQFYEQYEKVHPFLINDQPAPATERLQSPEQRDKLNGLYECILCACCSTSCPSF
WWNPDKFLGPSALLHADRFVSDSRDSDTRARLARLDDPFSLFRCRGIMNCVSVCPKGLNPTKAIGHLRNLLLDQAG

Sequences:

>Translated_236_residues
MSRGTRTIEIYRYDPDLDAAPRMQTYTIELLDSDRMLLDVLLRLKKEDETLTFRRSCREGICGSDGMNINGKNGLACLIN
MNTLPEKVTVRPLPGLPVVRDLVVDMNQFYEQYEKVHPFLINDQPAPATERLQSPEQRDKLNGLYECILCACCSTSCPSF
WWNPDKFLGPSALLHADRFVSDSRDSDTRARLARLDDPFSLFRCRGIMNCVSVCPKGLNPTKAIGHLRNLLLDQAG
>Mature_235_residues
SRGTRTIEIYRYDPDLDAAPRMQTYTIELLDSDRMLLDVLLRLKKEDETLTFRRSCREGICGSDGMNINGKNGLACLINM
NTLPEKVTVRPLPGLPVVRDLVVDMNQFYEQYEKVHPFLINDQPAPATERLQSPEQRDKLNGLYECILCACCSTSCPSFW
WNPDKFLGPSALLHADRFVSDSRDSDTRARLARLDDPFSLFRCRGIMNCVSVCPKGLNPTKAIGHLRNLLLDQAG

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=231, Percent_Identity=54.1125541125541, Blast_Score=258, Evalue=4e-69,
Organism=Escherichia coli, GI1786943, Length=232, Percent_Identity=65.948275862069, Blast_Score=326, Evalue=1e-90,
Organism=Escherichia coli, GI1790596, Length=219, Percent_Identity=37.4429223744292, Blast_Score=150, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17533915, Length=231, Percent_Identity=52.8138528138528, Blast_Score=250, Evalue=4e-67,
Organism=Saccharomyces cerevisiae, GI6322987, Length=230, Percent_Identity=51.7391304347826, Blast_Score=246, Evalue=3e-66,
Organism=Drosophila melanogaster, GI17137106, Length=234, Percent_Identity=54.7008547008547, Blast_Score=259, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24643156, Length=232, Percent_Identity=53.0172413793103, Blast_Score=242, Evalue=2e-64,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 26744; Mature: 26613

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRGTRTIEIYRYDPDLDAAPRMQTYTIELLDSDRMLLDVLLRLKKEDETLTFRRSCREG
CCCCCEEEEEEEECCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHCC
ICGSDGMNINGKNGLACLINMNTLPEKVTVRPLPGLPVVRDLVVDMNQFYEQYEKVHPFL
CCCCCCCEECCCCCEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEE
INDQPAPATERLQSPEQRDKLNGLYECILCACCSTSCPSFWWNPDKFLGPSALLHADRFV
ECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHH
SDSRDSDTRARLARLDDPFSLFRCRGIMNCVSVCPKGLNPTKAIGHLRNLLLDQAG
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRGTRTIEIYRYDPDLDAAPRMQTYTIELLDSDRMLLDVLLRLKKEDETLTFRRSCREG
CCCCEEEEEEEECCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHCC
ICGSDGMNINGKNGLACLINMNTLPEKVTVRPLPGLPVVRDLVVDMNQFYEQYEKVHPFL
CCCCCCCEECCCCCEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEE
INDQPAPATERLQSPEQRDKLNGLYECILCACCSTSCPSFWWNPDKFLGPSALLHADRFV
ECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHH
SDSRDSDTRARLARLDDPFSLFRCRGIMNCVSVCPKGLNPTKAIGHLRNLLLDQAG
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6388571; 8905232; 9278503; 6376123; 9298646 [H]