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The map label for this gene is udg [H]

Identifier: 92113983

GI number: 92113983

Start: 2113787

End: 2115079

Strand: Direct

Name: udg [H]

Synonym: Csal_1860

Alternate gene names: 92113983

Gene position: 2113787-2115079 (Clockwise)

Preceding gene: 92113982

Following gene: 92113985

Centisome position: 57.18

GC content: 65.27

Gene sequence:

>1293_bases
ATGCGCGTCAACGTGTATGGAAGCGAGCTTTCGGCCGCGGTGGCAGCGGCAGCGCTGTCTTCGGTAGGGCACCAGGTCGT
CTGGTGCCCCCATCCCGACTTCCCCTGGCATAGTCTGGAAAGCGCCGAATGGCTGATACGCGAGCCGGGGCTCAAGGAAC
AGATCGACACCGGCTGCCGCTCGGGCCTGCTGACGATTGCCGAGACGCCTGCGCATGGCGAGGTGGACATCCACTGGCTG
GCCCTGGCACCCGACCAGCGAGACGCGGCCGAGGCGTATGTGGCCGACGTGCCGGCCGCGCAGAGCACGCCGCTGGTGGT
GATCAACAACTCGACCTTCCCGGTGGGTCACACCGAACGCTTCGAGGCCTTGCTCGGTCATGCCGGACAGGTGGCCGTCG
CCTTGCCGGACATGCTGGAAGAAGGGCGTGCCTGGGAGACCTTCACGCGTCCCTCGCGCTGGCTGCTGGGCAGCGAGGAC
ACCCAGGCCACGCACCAGGTCCGCGAATTGCTGCGCGCCTTCAACCGCCGGCAAGACGTCTTCCAGCTCATGCCGCGGCG
CGCCGCGGAACTGACCAAGCTTGCCATCATCGGCATGCTGGCGACGCGCATCAGCTACATGAACGAGCTGGCGGGGCTCG
CCGATTCCCTGGACGTGGATGTCGAGCACGTGCGTCTGGGGATGGGCGCCGACAGCCGCATCGGCTTCGAGTATCTCTAT
CCCGGTTGCGGTTTCGGCGGTCCGAGCTTCTCGCGCGATCTCATGCGTCTGGCCGATGTCCAGCATGCCTCGGGGCGCGA
GTCGCTGTTGCTCGAGCATGTACTGGATATCAACGAGCAGAAGAAGGAGACGCTGTTCCGCAAGTTCTGGAACCACTTCC
ACGGCCAGCTCTTCGAGCGTCGAGTGGCGATCTGGGGGGCCGCGTTCAAGCCCGGCACCACGCGTATCGACCAGGCACCG
GTGCTCACCCTGCTCGATGCCTTGCTGGCACAGGGCGTCAACGTCAACGTTCACGACCCCGAGGCATTGCCGGCGCTGCG
TGCGTTGTATGGCGATCACCCACGCGTCACGTTCTGCGATGACGACTTCTATGCCGCATGCGACGGGGCGGATGCCCTGA
TGCTGGTGACGGAGTGGAAGTGCTACTGGAACCCCAACTGGCGGCAATTGAGCGAGCGCATGGCCACGCCGCTGATTCTC
GACGGACGCAACATCTTCGATCCCGACTATGTCGCGGCTCGCGGCTTGATCTATCGCGGTATTGGCCGGCGAGCGGATCC
GACAGGCGCCTGA

Upstream 100 bases:

>100_bases
GGGCTATCTCGAAGCCACCTTGGCGTTGGCCAAGCGCCATCCCCAGCATGGCGAAGGATTCCGCGCCTTGCTGAGCCGCT
ACGCCGACGAGGGCTGAGCC

Downstream 100 bases:

>100_bases
CCCCGACGAGCCCCGCCAATGCGGGGCTCACCGCGTGAAGCGGGCGAGCCAGGAGGGGAGAGCGTATTCGGCCCGGAGGT
TCTCAGTCGTTGAAGTTCTG

Product: UDP-glucose/GDP-mannose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MRVNVYGSELSAAVAAAALSSVGHQVVWCPHPDFPWHSLESAEWLIREPGLKEQIDTGCRSGLLTIAETPAHGEVDIHWL
ALAPDQRDAAEAYVADVPAAQSTPLVVINNSTFPVGHTERFEALLGHAGQVAVALPDMLEEGRAWETFTRPSRWLLGSED
TQATHQVRELLRAFNRRQDVFQLMPRRAAELTKLAIIGMLATRISYMNELAGLADSLDVDVEHVRLGMGADSRIGFEYLY
PGCGFGGPSFSRDLMRLADVQHASGRESLLLEHVLDINEQKKETLFRKFWNHFHGQLFERRVAIWGAAFKPGTTRIDQAP
VLTLLDALLAQGVNVNVHDPEALPALRALYGDHPRVTFCDDDFYAACDGADALMLVTEWKCYWNPNWRQLSERMATPLIL
DGRNIFDPDYVAARGLIYRGIGRRADPTGA

Sequences:

>Translated_430_residues
MRVNVYGSELSAAVAAAALSSVGHQVVWCPHPDFPWHSLESAEWLIREPGLKEQIDTGCRSGLLTIAETPAHGEVDIHWL
ALAPDQRDAAEAYVADVPAAQSTPLVVINNSTFPVGHTERFEALLGHAGQVAVALPDMLEEGRAWETFTRPSRWLLGSED
TQATHQVRELLRAFNRRQDVFQLMPRRAAELTKLAIIGMLATRISYMNELAGLADSLDVDVEHVRLGMGADSRIGFEYLY
PGCGFGGPSFSRDLMRLADVQHASGRESLLLEHVLDINEQKKETLFRKFWNHFHGQLFERRVAIWGAAFKPGTTRIDQAP
VLTLLDALLAQGVNVNVHDPEALPALRALYGDHPRVTFCDDDFYAACDGADALMLVTEWKCYWNPNWRQLSERMATPLIL
DGRNIFDPDYVAARGLIYRGIGRRADPTGA
>Mature_430_residues
MRVNVYGSELSAAVAAAALSSVGHQVVWCPHPDFPWHSLESAEWLIREPGLKEQIDTGCRSGLLTIAETPAHGEVDIHWL
ALAPDQRDAAEAYVADVPAAQSTPLVVINNSTFPVGHTERFEALLGHAGQVAVALPDMLEEGRAWETFTRPSRWLLGSED
TQATHQVRELLRAFNRRQDVFQLMPRRAAELTKLAIIGMLATRISYMNELAGLADSLDVDVEHVRLGMGADSRIGFEYLY
PGCGFGGPSFSRDLMRLADVQHASGRESLLLEHVLDINEQKKETLFRKFWNHFHGQLFERRVAIWGAAFKPGTTRIDQAP
VLTLLDALLAQGVNVNVHDPEALPALRALYGDHPRVTFCDDDFYAACDGADALMLVTEWKCYWNPNWRQLSERMATPLIL
DGRNIFDPDYVAARGLIYRGIGRRADPTGA

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=401, Percent_Identity=25.1870324189526, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI296040438, Length=327, Percent_Identity=26.2996941896024, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI296040443, Length=292, Percent_Identity=27.0547945205479, Blast_Score=127, Evalue=3e-29,
Organism=Escherichia coli, GI1788340, Length=257, Percent_Identity=26.0700389105058, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560350, Length=451, Percent_Identity=25.9423503325942, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI17136908, Length=429, Percent_Identity=28.6713286713287, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 47815; Mature: 47815

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVNVYGSELSAAVAAAALSSVGHQVVWCPHPDFPWHSLESAEWLIREPGLKEQIDTGCR
CEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHCCCCCHHHHHHHHH
SGLLTIAETPAHGEVDIHWLALAPDQRDAAEAYVADVPAAQSTPLVVINNSTFPVGHTER
CCCEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHH
FEALLGHAGQVAVALPDMLEEGRAWETFTRPSRWLLGSEDTQATHQVRELLRAFNRRQDV
HHHHHCCCCCEEEECHHHHHCCCCCHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHH
FQLMPRRAAELTKLAIIGMLATRISYMNELAGLADSLDVDVEHVRLGMGADSRIGFEYLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCEEEC
PGCGFGGPSFSRDLMRLADVQHASGRESLLLEHVLDINEQKKETLFRKFWNHFHGQLFER
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RVAIWGAAFKPGTTRIDQAPVLTLLDALLAQGVNVNVHDPEALPALRALYGDHPRVTFCD
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEC
DDFYAACDGADALMLVTEWKCYWNPNWRQLSERMATPLILDGRNIFDPDYVAARGLIYRG
CCCEEECCCCCEEEEEEEEEEEECCCHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHC
IGRRADPTGA
CCCCCCCCCC
>Mature Secondary Structure
MRVNVYGSELSAAVAAAALSSVGHQVVWCPHPDFPWHSLESAEWLIREPGLKEQIDTGCR
CEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHCCCCCHHHHHHHHH
SGLLTIAETPAHGEVDIHWLALAPDQRDAAEAYVADVPAAQSTPLVVINNSTFPVGHTER
CCCEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHH
FEALLGHAGQVAVALPDMLEEGRAWETFTRPSRWLLGSEDTQATHQVRELLRAFNRRQDV
HHHHHCCCCCEEEECHHHHHCCCCCHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHH
FQLMPRRAAELTKLAIIGMLATRISYMNELAGLADSLDVDVEHVRLGMGADSRIGFEYLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCEEEC
PGCGFGGPSFSRDLMRLADVQHASGRESLLLEHVLDINEQKKETLFRKFWNHFHGQLFER
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RVAIWGAAFKPGTTRIDQAPVLTLLDALLAQGVNVNVHDPEALPALRALYGDHPRVTFCD
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEC
DDFYAACDGADALMLVTEWKCYWNPNWRQLSERMATPLILDGRNIFDPDYVAARGLIYRG
CCCEEECCCCCEEEEEEEEEEEECCCHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHC
IGRRADPTGA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]