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The map label for this gene is ruvC

Identifier: 92113969

GI number: 92113969

Start: 2102696

End: 2103256

Strand: Direct

Name: ruvC

Synonym: Csal_1846

Alternate gene names: 92113969

Gene position: 2102696-2103256 (Clockwise)

Preceding gene: 92113968

Following gene: 92113970

Centisome position: 56.88

GC content: 68.98

Gene sequence:

>561_bases
GTGACGGGCGAGGGCTCGGCGACCATCCTGCTGGGCATCGACCCCGGCTCGCGCATCACCGGCTATGGCGTCGTCGATGT
CGCCACGCCCACTCCTCGCTACGTGGCCAGCGGCTGCATCCGCATCAAGAGCGACCAGCTGGCCCAGAAGCTCGCGCAAG
TCTATGCCGGCATCGGCGAGCTGATCGGCCTGCATCGCCCGCACGAGATCGCCATCGAGCAGGTCTTCATGTCGAAGAAC
GCCGACTCCGCGCTCAAGCTGGGCCAGGCACGCGGCACGGCGATCGTCTGCGCCGCCAACCATGGCCTCGAGGTATTCGA
GTACGCCCCCACCCAGATCAAGCAGGCCGTCACCGGTACCGGTGCGGCGACCAAGGAGCAGGTACAGCACATGGTCACCG
CGATCCTGGGGCTCGATGGCGTGCCGCAGGCCGATGCGGCCGATGCGCTGGCCATCGCCTTGACGCATGCCTACGCGCGC
CAGGGACGTTCGTTGCCGCCCTCGCGAGGGCGCCGTCGCAGCGGGTCGCGCCAGCGTTGGCGTGACTACCGCCCGAGCTG
A

Upstream 100 bases:

>100_bases
GCAAGGTCCTCAAGCTGTTCGACATGCTCGAGGATCTCGACGACGTGCAGAACGTCTACTCCAACGCCGATTTCTCGGAC
GCCGTCATGGCGGAACTCGA

Downstream 100 bases:

>100_bases
GGCGGGCTGCGTCGGGCGCTGGTCAGTCGCGGGGTGGATCAGTATAGTGTCAAGCCAGTCAATCGAAGGATTTGATGTGC
ATGATCGGACGCTTGCGTGG

Product: crossover junction endodeoxyribonuclease RuvC

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MTGEGSATILLGIDPGSRITGYGVVDVATPTPRYVASGCIRIKSDQLAQKLAQVYAGIGELIGLHRPHEIAIEQVFMSKN
ADSALKLGQARGTAIVCAANHGLEVFEYAPTQIKQAVTGTGAATKEQVQHMVTAILGLDGVPQADAADALAIALTHAYAR
QGRSLPPSRGRRRSGSRQRWRDYRPS

Sequences:

>Translated_186_residues
MTGEGSATILLGIDPGSRITGYGVVDVATPTPRYVASGCIRIKSDQLAQKLAQVYAGIGELIGLHRPHEIAIEQVFMSKN
ADSALKLGQARGTAIVCAANHGLEVFEYAPTQIKQAVTGTGAATKEQVQHMVTAILGLDGVPQADAADALAIALTHAYAR
QGRSLPPSRGRRRSGSRQRWRDYRPS
>Mature_185_residues
TGEGSATILLGIDPGSRITGYGVVDVATPTPRYVASGCIRIKSDQLAQKLAQVYAGIGELIGLHRPHEIAIEQVFMSKNA
DSALKLGQARGTAIVCAANHGLEVFEYAPTQIKQAVTGTGAATKEQVQHMVTAILGLDGVPQADAADALAIALTHAYARQ
GRSLPPSRGRRRSGSRQRWRDYRPS

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=171, Percent_Identity=57.3099415204678, Blast_Score=163, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_CHRSD (Q1QWG0)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_573897.1
- ProteinModelPortal:   Q1QWG0
- SMR:   Q1QWG0
- STRING:   Q1QWG0
- GeneID:   4028072
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_1846
- NMPDR:   fig|290398.4.peg.1746
- eggNOG:   COG0817
- HOGENOM:   HBG437552
- OMA:   PMQIKLA
- BioCyc:   CSAL290398:CSAL_1846-MONOMER
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 19745; Mature: 19614

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGEGSATILLGIDPGSRITGYGVVDVATPTPRYVASGCIRIKSDQLAQKLAQVYAGIGE
CCCCCCEEEEEEECCCCCEECCEEEEECCCCHHHHHHCEEEECHHHHHHHHHHHHHHHHH
LIGLHRPHEIAIEQVFMSKNADSALKLGQARGTAIVCAANHGLEVFEYAPTQIKQAVTGT
HHCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCEEEECCHHHHHHHHHCC
GAATKEQVQHMVTAILGLDGVPQADAADALAIALTHAYARQGRSLPPSRGRRRSGSRQRW
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
RDYRPS
HCCCCC
>Mature Secondary Structure 
TGEGSATILLGIDPGSRITGYGVVDVATPTPRYVASGCIRIKSDQLAQKLAQVYAGIGE
CCCCCEEEEEEECCCCCEECCEEEEECCCCHHHHHHCEEEECHHHHHHHHHHHHHHHHH
LIGLHRPHEIAIEQVFMSKNADSALKLGQARGTAIVCAANHGLEVFEYAPTQIKQAVTGT
HHCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCEEEECCHHHHHHHHHCC
GAATKEQVQHMVTAILGLDGVPQADAADALAIALTHAYARQGRSLPPSRGRRRSGSRQRW
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
RDYRPS
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA