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The map label for this gene is aspS

Identifier: 92113967

GI number: 92113967

Start: 2100068

End: 2101846

Strand: Direct

Name: aspS

Synonym: Csal_1844

Alternate gene names: 92113967

Gene position: 2100068-2101846 (Clockwise)

Preceding gene: 92113966

Following gene: 92113968

Centisome position: 56.81

GC content: 63.74

Gene sequence:

>1779_bases
ATGCGCAGTCACTATTGCGGTCAGTTGAACGAAACCTTGGTGGACGAGGAAGTCGCATTGTGCGGCTGGGTGCATCGTCG
TCGCGATCACGGGGGGGTGATTTTCCTCGACCTTCGCGACCGCGATGGCATCGCCCAGGTCGTCGTCGACCCCGATACGC
CCGAGGCGTTCGCCAATGCCGATCGCGCCCGCAACGAGTTCGTGCTGCGCATTCGCGGACGCATTCGCCTGCGCCCCGAG
GGCACGCAGAATGCCCACATGCCGACCGGCATGATCGAGGTGCTGGCCAAGGACGTGGAGGTGCTCAACACCGCCGCGAC
ACCGCCGTTCCAGCTCGACGAGCACGGCAAGGTCGGCGAGGAAATTCGCCTCAAGCATCGCTACATCGATCTGCGCCGTC
CGGAGATGATCGACAAGCTGCGCCTGCGCTCGCGCATCACGCACAGCGTGCGTGCCTATCTCGAGGGCCAGGGGTTCCTC
GACATCGAGACGCCGATCCTGACACGCGCCACGCCGGAAGGCGCGCGCGACTACCTGGTGCCCAGCCGTACCCACGCCGG
CGAGTTCTTCGCCTTGCCGCAGTCGCCGCAGCTGTTCAAGCAATTGCTGATGGTCTCGGGGTTCGATCGCTACTACCAGA
TCGCCAAGTGTTTCCGTGACGAGGACCTGCGCGCCGATCGTCAGCCCGAATTCACGCAGATCGACCTCGAGGCATCGTTC
GTCGAGGAAAGCGACATCATGTCCCTCACCGAAGACATGATCCGTCGCCTGTTCCAGGACGTGCTCGATGTCGAACTGCC
GGCATTTCCGAAGATGCCCTACAGCGAAGCGATGAATCGCTATGGCTCCGACAAGCCGGACCTGCGTATTCCGCTGGAAC
TGGTCGACGTCGACGACCTGATGCAGGGTGTCGACTTCAAGGTGTTCTCCGGTCCGGCCAAGGCCGATGACGGCCGCGTG
GCGGCGCTCAAGGTCACCGGTGGCGCCACGCTGTCGCGCAAGGAAATCGACGCCTACACGGACTTCGTGAATATCTACGG
CGCCAAGGGGCTGGCCTGGATCAAGGTCAACGAGCGTGCCAAGGGCATCCAGGGGCTGCAGTCGCCGATCGTCAAGTTCA
TGGAAGACATCATCGAGTCGTTGCTCGACCGGGTGGGCGCCGAGGATGGCGACATCATCTTCTTCGGTGCCGACAAGGCA
CGCATCGTCAATGAGGCGCTGGGAGCCCTGCGCGTCAAGCTGGGCGAGGACCTCGACCTCTACACCCAGGCGTGGGCGCC
GTTGTGGGTCGTCGACTTCCCCATGTTCGAAGCCGACGACAACGGTCGTCTGGCCGCCTTGCACCATCCGTTCACCGCGC
CGTCGTGCACGCCGGAAGCCTTCAAGGCGGACCCCGCCAATGCGCTGTCGCGGGCCTACGACATGGTCCTCAACGGCACC
GAGCTGGGCGGCGGCTCGATCCGTATTCATGACCAGACGATGCAGCGTGCGGTCTTCGAGGTGCTGGGCATCGGCGAGGA
AGAGGCCGACGAGAAATTCGGCTTCCTGCTCGATGCCCTCAAGTTCGGTGCGCCGCCCCACGGTGGCCTGGCCTTCGGCC
TCGACCGGCTGGTCATGCTGATGAGCGGTGCCAGAACGATTCGCGAAGTGATCGCTTTCCCCAAGACGCAAAGCGCGGCT
TGCCTGATGACCGACGCCCCGGGCGAGGTCAGTGCCGAGCAGCTCAAGGAGCTCAACATTCGCCTGCGTCAAAAGGCGCA
GAACAACGGCGACGTCTGA

Upstream 100 bases:

>100_bases
CCCTGCCGATACCGGCGGCAAGACGCCGGCCTGACGCATTCGGCGCCGTACGGGCGGCGCCGAATCGCCCCATGAGACAA
GCAACGAAACAGGATCAGAC

Downstream 100 bases:

>100_bases
CGGAGGCCGCACGTCCTGCGTCCTTCTCGTTGTCCCGGCGCCCCTCGGGCGCCGGGTGTCCTGCAAACCGCGAACGCCTG
TATTTCCAAGGAGTGACGTC

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MRSHYCGQLNETLVDEEVALCGWVHRRRDHGGVIFLDLRDRDGIAQVVVDPDTPEAFANADRARNEFVLRIRGRIRLRPE
GTQNAHMPTGMIEVLAKDVEVLNTAATPPFQLDEHGKVGEEIRLKHRYIDLRRPEMIDKLRLRSRITHSVRAYLEGQGFL
DIETPILTRATPEGARDYLVPSRTHAGEFFALPQSPQLFKQLLMVSGFDRYYQIAKCFRDEDLRADRQPEFTQIDLEASF
VEESDIMSLTEDMIRRLFQDVLDVELPAFPKMPYSEAMNRYGSDKPDLRIPLELVDVDDLMQGVDFKVFSGPAKADDGRV
AALKVTGGATLSRKEIDAYTDFVNIYGAKGLAWIKVNERAKGIQGLQSPIVKFMEDIIESLLDRVGAEDGDIIFFGADKA
RIVNEALGALRVKLGEDLDLYTQAWAPLWVVDFPMFEADDNGRLAALHHPFTAPSCTPEAFKADPANALSRAYDMVLNGT
ELGGGSIRIHDQTMQRAVFEVLGIGEEEADEKFGFLLDALKFGAPPHGGLAFGLDRLVMLMSGARTIREVIAFPKTQSAA
CLMTDAPGEVSAEQLKELNIRLRQKAQNNGDV

Sequences:

>Translated_592_residues
MRSHYCGQLNETLVDEEVALCGWVHRRRDHGGVIFLDLRDRDGIAQVVVDPDTPEAFANADRARNEFVLRIRGRIRLRPE
GTQNAHMPTGMIEVLAKDVEVLNTAATPPFQLDEHGKVGEEIRLKHRYIDLRRPEMIDKLRLRSRITHSVRAYLEGQGFL
DIETPILTRATPEGARDYLVPSRTHAGEFFALPQSPQLFKQLLMVSGFDRYYQIAKCFRDEDLRADRQPEFTQIDLEASF
VEESDIMSLTEDMIRRLFQDVLDVELPAFPKMPYSEAMNRYGSDKPDLRIPLELVDVDDLMQGVDFKVFSGPAKADDGRV
AALKVTGGATLSRKEIDAYTDFVNIYGAKGLAWIKVNERAKGIQGLQSPIVKFMEDIIESLLDRVGAEDGDIIFFGADKA
RIVNEALGALRVKLGEDLDLYTQAWAPLWVVDFPMFEADDNGRLAALHHPFTAPSCTPEAFKADPANALSRAYDMVLNGT
ELGGGSIRIHDQTMQRAVFEVLGIGEEEADEKFGFLLDALKFGAPPHGGLAFGLDRLVMLMSGARTIREVIAFPKTQSAA
CLMTDAPGEVSAEQLKELNIRLRQKAQNNGDV
>Mature_592_residues
MRSHYCGQLNETLVDEEVALCGWVHRRRDHGGVIFLDLRDRDGIAQVVVDPDTPEAFANADRARNEFVLRIRGRIRLRPE
GTQNAHMPTGMIEVLAKDVEVLNTAATPPFQLDEHGKVGEEIRLKHRYIDLRRPEMIDKLRLRSRITHSVRAYLEGQGFL
DIETPILTRATPEGARDYLVPSRTHAGEFFALPQSPQLFKQLLMVSGFDRYYQIAKCFRDEDLRADRQPEFTQIDLEASF
VEESDIMSLTEDMIRRLFQDVLDVELPAFPKMPYSEAMNRYGSDKPDLRIPLELVDVDDLMQGVDFKVFSGPAKADDGRV
AALKVTGGATLSRKEIDAYTDFVNIYGAKGLAWIKVNERAKGIQGLQSPIVKFMEDIIESLLDRVGAEDGDIIFFGADKA
RIVNEALGALRVKLGEDLDLYTQAWAPLWVVDFPMFEADDNGRLAALHHPFTAPSCTPEAFKADPANALSRAYDMVLNGT
ELGGGSIRIHDQTMQRAVFEVLGIGEEEADEKFGFLLDALKFGAPPHGGLAFGLDRLVMLMSGARTIREVIAFPKTQSAA
CLMTDAPGEVSAEQLKELNIRLRQKAQNNGDV

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI40789249, Length=607, Percent_Identity=39.0444810543657, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI5031815, Length=266, Percent_Identity=27.0676691729323, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI194272210, Length=266, Percent_Identity=27.0676691729323, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI45439306, Length=263, Percent_Identity=27.3764258555133, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4758762, Length=244, Percent_Identity=25.8196721311475, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI226491502, Length=268, Percent_Identity=25.3731343283582, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788173, Length=592, Percent_Identity=60.3040540540541, Blast_Score=736, Evalue=0.0,
Organism=Escherichia coli, GI1789256, Length=301, Percent_Identity=28.9036544850498, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790571, Length=302, Percent_Identity=28.1456953642384, Blast_Score=99, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI32566633, Length=604, Percent_Identity=36.7549668874172, Blast_Score=345, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI71994340, Length=268, Percent_Identity=23.8805970149254, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17535925, Length=268, Percent_Identity=23.8805970149254, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17535927, Length=268, Percent_Identity=23.8805970149254, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17551876, Length=281, Percent_Identity=25.9786476868327, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71984122, Length=282, Percent_Identity=26.241134751773, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325153, Length=625, Percent_Identity=32.64, Blast_Score=280, Evalue=4e-76,
Organism=Saccharomyces cerevisiae, GI6320242, Length=265, Percent_Identity=26.4150943396226, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321807, Length=255, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323011, Length=247, Percent_Identity=27.1255060728745, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6324256, Length=152, Percent_Identity=25, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584738, Length=598, Percent_Identity=38.9632107023411, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24640849, Length=261, Percent_Identity=26.4367816091954, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24640851, Length=261, Percent_Identity=26.4367816091954, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17136276, Length=254, Percent_Identity=27.9527559055118, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19921528, Length=231, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_CHRSD (Q1QWG2)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_573895.1
- ProteinModelPortal:   Q1QWG2
- SMR:   Q1QWG2
- STRING:   Q1QWG2
- GeneID:   4028070
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_1844
- NMPDR:   fig|290398.4.peg.1647
- eggNOG:   COG0173
- HOGENOM:   HBG396032
- OMA:   AFPKTQQ
- ProtClustDB:   PRK00476
- BioCyc:   CSAL290398:CSAL_1844-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00044_B
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.30.1360.30
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF5
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00459

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 66204; Mature: 66204

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSHYCGQLNETLVDEEVALCGWVHRRRDHGGVIFLDLRDRDGIAQVVVDPDTPEAFANA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCHHHHCH
DRARNEFVLRIRGRIRLRPEGTQNAHMPTGMIEVLAKDVEVLNTAATPPFQLDEHGKVGE
HHCCCEEEEEEECEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
EIRLKHRYIDLRRPEMIDKLRLRSRITHSVRAYLEGQGFLDIETPILTRATPEGARDYLV
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCCCCCC
PSRTHAGEFFALPQSPQLFKQLLMVSGFDRYYQIAKCFRDEDLRADRQPEFTQIDLEASF
CCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHH
VEESDIMSLTEDMIRRLFQDVLDVELPAFPKMPYSEAMNRYGSDKPDLRIPLELVDVDDL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEEECHHHH
MQGVDFKVFSGPAKADDGRVAALKVTGGATLSRKEIDAYTDFVNIYGAKGLAWIKVNERA
HCCCCEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHH
KGIQGLQSPIVKFMEDIIESLLDRVGAEDGDIIFFGADKARIVNEALGALRVKLGEDLDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCHH
YTQAWAPLWVVDFPMFEADDNGRLAALHHPFTAPSCTPEAFKADPANALSRAYDMVLNGT
HHHCCCCEEEEECCEEECCCCCCEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCC
ELGGGSIRIHDQTMQRAVFEVLGIGEEEADEKFGFLLDALKFGAPPHGGLAFGLDRLVML
CCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
MSGARTIREVIAFPKTQSAACLMTDAPGEVSAEQLKELNIRLRQKAQNNGDV
HHCHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRSHYCGQLNETLVDEEVALCGWVHRRRDHGGVIFLDLRDRDGIAQVVVDPDTPEAFANA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCHHHHCH
DRARNEFVLRIRGRIRLRPEGTQNAHMPTGMIEVLAKDVEVLNTAATPPFQLDEHGKVGE
HHCCCEEEEEEECEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
EIRLKHRYIDLRRPEMIDKLRLRSRITHSVRAYLEGQGFLDIETPILTRATPEGARDYLV
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCCCCCC
PSRTHAGEFFALPQSPQLFKQLLMVSGFDRYYQIAKCFRDEDLRADRQPEFTQIDLEASF
CCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHH
VEESDIMSLTEDMIRRLFQDVLDVELPAFPKMPYSEAMNRYGSDKPDLRIPLELVDVDDL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEEECHHHH
MQGVDFKVFSGPAKADDGRVAALKVTGGATLSRKEIDAYTDFVNIYGAKGLAWIKVNERA
HCCCCEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHH
KGIQGLQSPIVKFMEDIIESLLDRVGAEDGDIIFFGADKARIVNEALGALRVKLGEDLDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCHH
YTQAWAPLWVVDFPMFEADDNGRLAALHHPFTAPSCTPEAFKADPANALSRAYDMVLNGT
HHHCCCCEEEEECCEEECCCCCCEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCC
ELGGGSIRIHDQTMQRAVFEVLGIGEEEADEKFGFLLDALKFGAPPHGGLAFGLDRLVML
CCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
MSGARTIREVIAFPKTQSAACLMTDAPGEVSAEQLKELNIRLRQKAQNNGDV
HHCHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA