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The map label for this gene is allD [C]

Identifier: 92113894

GI number: 92113894

Start: 2016020

End: 2017021

Strand: Direct

Name: allD [C]

Synonym: Csal_1771

Alternate gene names: 92113894

Gene position: 2016020-2017021 (Clockwise)

Preceding gene: 92113893

Following gene: 92113897

Centisome position: 54.54

GC content: 69.86

Gene sequence:

>1002_bases
ATGAGCCGCATGATATCGCTGCGCGAGGCCGAAACGCTGGCGGTCGCGGCACTCGAGGCGGTCGGCGTGCCGCGCTGGGA
GGCCGAGGTCACGGCCCGGGCACTGATCGACGCCGAACGTGACGGGCTGGCGTCCCACGGCTTGTCACGGTTGCCGTTCT
ATCTTGCCCAGGCGCGCAGTGGCAAGGTCGTTGCCGATGCGCAGGCGCGGGTCGAGGTCGCCGGCTCGGTGATTCGGGTC
GATGCCCGACACGGCCTGGCGTTTCCGGCCATTGCCCGGGGCGTGGAGCGCGCCATTCCGCTGGCCCGCGAGCTGGGACT
GGTCGCCGTGGCGATCGGCGGTTCGCACCATTTCGGGGTCGCCGGCGCGCCGGTCGAACGCCTGGCCCGCGAAGGGCTGG
TGGCGATGGCCTTCAGCAATGCGCCTTCGGCCATGGCGCCGTGGGGAGGCAAGCGTCCGCTCTACGGCACCAACCCGATC
GCGTTCGCGACGCCACGACGGGGGACCGATCCGCTGGTCATCGACCTGTCCCTGTCGAAGGTCGCCCGGGGCAAGGTGAT
GCTGGCCAAGAAGGCCGGCGAGCCGATTCCCGAAGGCTGGGCGCTCGACATCGAGGGACGACCCACGACCGACCCGGACG
CGGCGATCGCGGGCAGCATGGTTCCGGCCGGCGATGCCAAGGGGGCCTCGCTGGCGTTGATGGTGGAATTGCTGACCGCC
GGACTCACCGGTAGTCACTTCGGCTTCCAGGCGAGTTCCTTCTTCGAGCCCGAGGGCGAGGCGCCGAGTGTCGGCCACCT
GATGCTGGCCTTCGATCCGGCCCACTTCTCCGATGGTTACCTCGAGCACATCGAGGCGCTGTTCCAGGCCATGCTCGAGC
AGGAAGGTGTGCGGCTGCCCGGCACCCGGCGCCATGCCTTGCGCCGCGAACGCGGCGAGTCGCTCGAACTGCCCGAAGCC
GTGGTCGACGAGCTGCGTGCCTATGCCGTGTCCCGCGTGTAA

Upstream 100 bases:

>100_bases
TGATCGCCACGCCGCACATCGCCGGCGTGACCCACGAGTCCAACGAGCGGATCAGCTGGATCACCGTCGACAACGTGCGC
CGTGCGCTGGGGGTGAGGGC

Downstream 100 bases:

>100_bases
CGGGCCACCGGGTGGCATGGCCTCAGGCTGAACGGGCCAGCGCCTCGAACTGCGGCAGCACGGTCTCCTTGAGGAAGGGG
CGGTAGTGCGCTTCGGTGAC

Product: malate dehydrogenase (NADP+)

Products: oxaloacetate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSRMISLREAETLAVAALEAVGVPRWEAEVTARALIDAERDGLASHGLSRLPFYLAQARSGKVVADAQARVEVAGSVIRV
DARHGLAFPAIARGVERAIPLARELGLVAVAIGGSHHFGVAGAPVERLAREGLVAMAFSNAPSAMAPWGGKRPLYGTNPI
AFATPRRGTDPLVIDLSLSKVARGKVMLAKKAGEPIPEGWALDIEGRPTTDPDAAIAGSMVPAGDAKGASLALMVELLTA
GLTGSHFGFQASSFFEPEGEAPSVGHLMLAFDPAHFSDGYLEHIEALFQAMLEQEGVRLPGTRRHALRRERGESLELPEA
VVDELRAYAVSRV

Sequences:

>Translated_333_residues
MSRMISLREAETLAVAALEAVGVPRWEAEVTARALIDAERDGLASHGLSRLPFYLAQARSGKVVADAQARVEVAGSVIRV
DARHGLAFPAIARGVERAIPLARELGLVAVAIGGSHHFGVAGAPVERLAREGLVAMAFSNAPSAMAPWGGKRPLYGTNPI
AFATPRRGTDPLVIDLSLSKVARGKVMLAKKAGEPIPEGWALDIEGRPTTDPDAAIAGSMVPAGDAKGASLALMVELLTA
GLTGSHFGFQASSFFEPEGEAPSVGHLMLAFDPAHFSDGYLEHIEALFQAMLEQEGVRLPGTRRHALRRERGESLELPEA
VVDELRAYAVSRV
>Mature_332_residues
SRMISLREAETLAVAALEAVGVPRWEAEVTARALIDAERDGLASHGLSRLPFYLAQARSGKVVADAQARVEVAGSVIRVD
ARHGLAFPAIARGVERAIPLARELGLVAVAIGGSHHFGVAGAPVERLAREGLVAMAFSNAPSAMAPWGGKRPLYGTNPIA
FATPRRGTDPLVIDLSLSKVARGKVMLAKKAGEPIPEGWALDIEGRPTTDPDAAIAGSMVPAGDAKGASLALMVELLTAG
LTGSHFGFQASSFFEPEGEAPSVGHLMLAFDPAHFSDGYLEHIEALFQAMLEQEGVRLPGTRRHALRRERGESLELPEAV
VDELRAYAVSRV

Specific function: Involved In The Anaerobic Utilization Of Allantoin. [C]

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1786727, Length=340, Percent_Identity=30.5882352941176, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1787020, Length=312, Percent_Identity=29.1666666666667, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1790000, Length=291, Percent_Identity=24.3986254295533, Blast_Score=104, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17536633, Length=298, Percent_Identity=29.1946308724832, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17507179, Length=295, Percent_Identity=28.8135593220339, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24667904, Length=291, Percent_Identity=27.8350515463918, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24667908, Length=291, Percent_Identity=27.8350515463918, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI45553211, Length=291, Percent_Identity=27.8350515463918, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24667912, Length=291, Percent_Identity=27.8350515463918, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24658010, Length=341, Percent_Identity=26.9794721407625, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24648360, Length=302, Percent_Identity=26.4900662251656, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.37

Molecular weight: Translated: 35183; Mature: 35052

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRMISLREAETLAVAALEAVGVPRWEAEVTARALIDAERDGLASHGLSRLPFYLAQARS
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCC
GKVVADAQARVEVAGSVIRVDARHGLAFPAIARGVERAIPLARELGLVAVAIGGSHHFGV
CCEEECCHHHHEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCC
AGAPVERLAREGLVAMAFSNAPSAMAPWGGKRPLYGTNPIAFATPRRGTDPLVIDLSLSK
CCCHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEHHH
VARGKVMLAKKAGEPIPEGWALDIEGRPTTDPDAAIAGSMVPAGDAKGASLALMVELLTA
HHCCEEEEEECCCCCCCCCCEEEECCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHC
GLTGSHFGFQASSFFEPEGEAPSVGHLMLAFDPAHFSDGYLEHIEALFQAMLEQEGVRLP
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCC
GTRRHALRRERGESLELPEAVVDELRAYAVSRV
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRMISLREAETLAVAALEAVGVPRWEAEVTARALIDAERDGLASHGLSRLPFYLAQARS
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCC
GKVVADAQARVEVAGSVIRVDARHGLAFPAIARGVERAIPLARELGLVAVAIGGSHHFGV
CCEEECCHHHHEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCC
AGAPVERLAREGLVAMAFSNAPSAMAPWGGKRPLYGTNPIAFATPRRGTDPLVIDLSLSK
CCCHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEHHH
VARGKVMLAKKAGEPIPEGWALDIEGRPTTDPDAAIAGSMVPAGDAKGASLALMVELLTA
HHCCEEEEEECCCCCCCCCCEEEECCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHC
GLTGSHFGFQASSFFEPEGEAPSVGHLMLAFDPAHFSDGYLEHIEALFQAMLEQEGVRLP
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCC
GTRRHALRRERGESLELPEAVVDELRAYAVSRV
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-malate; NAD+

Specific reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]