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The map label for this gene is gbpR [H]

Identifier: 92113880

GI number: 92113880

Start: 2002493

End: 2003446

Strand: Direct

Name: gbpR [H]

Synonym: Csal_1757

Alternate gene names: 92113880

Gene position: 2002493-2003446 (Clockwise)

Preceding gene: 92113873

Following gene: 92113881

Centisome position: 54.17

GC content: 66.98

Gene sequence:

>954_bases
ATGACGACGGGCAAGCTGTCCCACGCGCATCTCTGCGGTTGGCTGCGTTTCAAGCATCTGACGCTTCTCACCACGCTGGC
GGAGAGCCGCAACATGCACGCCACGGCGCGGGTGATGCACCTGAGCCAGCCGGCCGCGAGCAAGATGCTGCGGGACCTGG
AGGTATACTTCGGATTTGCGCTTTTCGAACGCCTGCCGCGTGCCATGCAGCCCACCGAGCTGGGAGAGCAGGTCATCCGC
CATGCCTGGATCCTGCTCAACGACATGGAGCGCCTGGTCGACGACATCAACGATCTGCGCGAGGGCGGCTACGGCCAACT
GCTGATCGGCGCGATCGCGGCGGCCGCGCCGGAGATCCTGCCGGCGGCCATCGCACGTCTCAAGCAGGCCCGGCCGCGCC
TGTCGGTGAGTCTGCAGGAGCAGACCAGCGACAGACTGCTGCTCGAGCTGGAGCACAAGCGTCTCGATCTGGTCATCGGG
CGCTTGACGCATGTCAGCCAGCACAACCTGTTCGATTTCGAGCCGCTGCTGGACGAACCGCTGCGGGTCGTGGTGCGTCG
CGATCACCCTCTGACCCGGCGTGGCGAGGCGCCTTCGCTGGACGAGCTGAGTCACTGGCCCTGGATCCTGCATCCCTTGT
CGAGCCCCATGCGCGGCGTGTTCGAGTCGGCGCTGGCCGAGGAAGGGATCGCGACGCCGGCCAACGTTGTCGAAACCACG
TCCATCCAGGCGACGCTGCAGCTGCTGCAGTCCTCGGACATGCTCGCGGTGCTGCCACGCTCCGTCATGCGTCGTCCCCT
GGCGGGGGGCCAGTACGTGGTCCTCGAACGCGTGATCGGCAAGCCGCTGGACTACTACGGCATCATCACCCGCCGCCAGG
AGCCGTTGTCGCCCGCGGTGGAGGAACTGGTCGTGCACTTGCGCCGGCTGGCCGCCGAAGCCGACGGTCGCTGA

Upstream 100 bases:

>100_bases
ATCGAAGTTTGTGGCATTGTGATTCCTCTGGGTTATCGGCAAGTCGAGCGGGCATGCGCCATGGGCACGCGCCGCTCGTG
ACGACGAGGATGTTTTCACC

Downstream 100 bases:

>100_bases
CATGGCTTGTCCTTAAGTCTAATGCCGGTCGGCCCCGCAATCTGGAATCCTGACACGCACTTAGTGTGATGTATGACAGC
ATGCCGTGTCCGGATGCTGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTTGKLSHAHLCGWLRFKHLTLLTTLAESRNMHATARVMHLSQPAASKMLRDLEVYFGFALFERLPRAMQPTELGEQVIR
HAWILLNDMERLVDDINDLREGGYGQLLIGAIAAAAPEILPAAIARLKQARPRLSVSLQEQTSDRLLLELEHKRLDLVIG
RLTHVSQHNLFDFEPLLDEPLRVVVRRDHPLTRRGEAPSLDELSHWPWILHPLSSPMRGVFESALAEEGIATPANVVETT
SIQATLQLLQSSDMLAVLPRSVMRRPLAGGQYVVLERVIGKPLDYYGIITRRQEPLSPAVEELVVHLRRLAAEADGR

Sequences:

>Translated_317_residues
MTTGKLSHAHLCGWLRFKHLTLLTTLAESRNMHATARVMHLSQPAASKMLRDLEVYFGFALFERLPRAMQPTELGEQVIR
HAWILLNDMERLVDDINDLREGGYGQLLIGAIAAAAPEILPAAIARLKQARPRLSVSLQEQTSDRLLLELEHKRLDLVIG
RLTHVSQHNLFDFEPLLDEPLRVVVRRDHPLTRRGEAPSLDELSHWPWILHPLSSPMRGVFESALAEEGIATPANVVETT
SIQATLQLLQSSDMLAVLPRSVMRRPLAGGQYVVLERVIGKPLDYYGIITRRQEPLSPAVEELVVHLRRLAAEADGR
>Mature_316_residues
TTGKLSHAHLCGWLRFKHLTLLTTLAESRNMHATARVMHLSQPAASKMLRDLEVYFGFALFERLPRAMQPTELGEQVIRH
AWILLNDMERLVDDINDLREGGYGQLLIGAIAAAAPEILPAAIARLKQARPRLSVSLQEQTSDRLLLELEHKRLDLVIGR
LTHVSQHNLFDFEPLLDEPLRVVVRRDHPLTRRGEAPSLDELSHWPWILHPLSSPMRGVFESALAEEGIATPANVVETTS
IQATLQLLQSSDMLAVLPRSVMRRPLAGGQYVVLERVIGKPLDYYGIITRRQEPLSPAVEELVVHLRRLAAEADGR

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=305, Percent_Identity=27.5409836065574, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787601, Length=297, Percent_Identity=26.2626262626263, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1790399, Length=305, Percent_Identity=28.5245901639344, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI145693105, Length=292, Percent_Identity=26.7123287671233, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789506, Length=260, Percent_Identity=23.0769230769231, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI157672245, Length=295, Percent_Identity=25.4237288135593, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788887, Length=271, Percent_Identity=26.5682656826568, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35659; Mature: 35528

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGKLSHAHLCGWLRFKHLTLLTTLAESRNMHATARVMHLSQPAASKMLRDLEVYFGFA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LFERLPRAMQPTELGEQVIRHAWILLNDMERLVDDINDLREGGYGQLLIGAIAAAAPEIL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
PAAIARLKQARPRLSVSLQEQTSDRLLLELEHKRLDLVIGRLTHVSQHNLFDFEPLLDEP
HHHHHHHHHCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LRVVVRRDHPLTRRGEAPSLDELSHWPWILHPLSSPMRGVFESALAEEGIATPANVVETT
HHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHH
SIQATLQLLQSSDMLAVLPRSVMRRPLAGGQYVVLERVIGKPLDYYGIITRRQEPLSPAV
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCHHH
EELVVHLRRLAAEADGR
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTGKLSHAHLCGWLRFKHLTLLTTLAESRNMHATARVMHLSQPAASKMLRDLEVYFGFA
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LFERLPRAMQPTELGEQVIRHAWILLNDMERLVDDINDLREGGYGQLLIGAIAAAAPEIL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
PAAIARLKQARPRLSVSLQEQTSDRLLLELEHKRLDLVIGRLTHVSQHNLFDFEPLLDEP
HHHHHHHHHCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LRVVVRRDHPLTRRGEAPSLDELSHWPWILHPLSSPMRGVFESALAEEGIATPANVVETT
HHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHH
SIQATLQLLQSSDMLAVLPRSVMRRPLAGGQYVVLERVIGKPLDYYGIITRRQEPLSPAV
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCHHH
EELVVHLRRLAAEADGR
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]