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The map label for this gene is era [H]

Identifier: 92113756

GI number: 92113756

Start: 1854586

End: 1855485

Strand: Direct

Name: era [H]

Synonym: Csal_1632

Alternate gene names: 92113756

Gene position: 1854586-1855485 (Clockwise)

Preceding gene: 92113755

Following gene: 92113757

Centisome position: 50.17

GC content: 63.44

Gene sequence:

>900_bases
ATGACGCAACACTGTGGTTTCGTGGCCATCGTCGGTCGCCCCAACGTCGGGAAATCGACGTTGATGAACCGGATACTCGG
TCAGAAAATCTCCATCACCTCGCGGCGGCCGCAGACCACGCGTCACCAGGTGATGGGCATCAAGACCGAGGGGGAGACCC
AGTTCATCTACGTCGATACGCCGGGGATGCACATCCAGACCCGCGATCGCAACAAGGCGATCAACCGCTTCATGAACCAG
GCGGCCACGCATGCCCTGCGCGATATCGACTGCGTGATCTTCATCGTCGACCGCACCAAGTGGACCGCGGAAGACGATGT
GGTGCTGGAAAAGCTCGGCCAGGTCCCCGCGCCGGTGATCCTGGCCGTCAACAAGGTCGATTGGCTCGAGGACAAGAGCA
GCCTGCTGCCGTGGCTGGACAGCATCAGCCGCAAGCGCGAGTTCGCCGCCGTGGTGCCCATCTCGGCCAAGCACGGCACC
AACGTGCCGGAGCTCGAGGCCGAGATCGCCCAGCGCCTGCCGGAGAGCGTGCACTATTTCCCGGAAGACCAGATCACCGA
CAAGAGCCAGCGCTTCCTGGCCGCCGAGCTGGTGCGCGAGAAGGTCATGCGCCAGCTCGGTGACGAGCTGCCGTACCAGA
TGACCGTCGAGATCGAGGAATTCAAGGACGACGGCAAGACGCTGCACATCAGCGCGCTGATCATGGTCGAGCGGCCGGGC
CAGAAGAAGATCCTGATCGGGGAGCGCGGCGAGCGCATCAAGAGCATCGGACGCGAGGCCCGCCTGGAGATGGAGCGCGC
CTTCGACGCCAAGGTCATGCTCAACCTGTGGGTGAAGGTCAAGCGTGGCTGGTCCGACGACGACCGTGCCCTGAAGAGCC
TCGGCTACGATCTCGACTGA

Upstream 100 bases:

>100_bases
AGGATCATACGCTGGGTGTCGGCTCCAGCCGCCGTCACGCCGAGCAGCAGGCCGCCGAAAAGGCGCTTGAAACTCTCGAA
CCTTCCCGGGGCAAGCACGC

Downstream 100 bases:

>100_bases
TTGCGCCCACCACGGCGCGGAGATGCCGCGATGACGCCCGAACCGGCCTTTTTGCTGCACAAGCGTGCCTACCGCGAGAC
CAGTGCCATCGTCGAGTTGC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTQHCGFVAIVGRPNVGKSTLMNRILGQKISITSRRPQTTRHQVMGIKTEGETQFIYVDTPGMHIQTRDRNKAINRFMNQ
AATHALRDIDCVIFIVDRTKWTAEDDVVLEKLGQVPAPVILAVNKVDWLEDKSSLLPWLDSISRKREFAAVVPISAKHGT
NVPELEAEIAQRLPESVHYFPEDQITDKSQRFLAAELVREKVMRQLGDELPYQMTVEIEEFKDDGKTLHISALIMVERPG
QKKILIGERGERIKSIGREARLEMERAFDAKVMLNLWVKVKRGWSDDDRALKSLGYDLD

Sequences:

>Translated_299_residues
MTQHCGFVAIVGRPNVGKSTLMNRILGQKISITSRRPQTTRHQVMGIKTEGETQFIYVDTPGMHIQTRDRNKAINRFMNQ
AATHALRDIDCVIFIVDRTKWTAEDDVVLEKLGQVPAPVILAVNKVDWLEDKSSLLPWLDSISRKREFAAVVPISAKHGT
NVPELEAEIAQRLPESVHYFPEDQITDKSQRFLAAELVREKVMRQLGDELPYQMTVEIEEFKDDGKTLHISALIMVERPG
QKKILIGERGERIKSIGREARLEMERAFDAKVMLNLWVKVKRGWSDDDRALKSLGYDLD
>Mature_298_residues
TQHCGFVAIVGRPNVGKSTLMNRILGQKISITSRRPQTTRHQVMGIKTEGETQFIYVDTPGMHIQTRDRNKAINRFMNQA
ATHALRDIDCVIFIVDRTKWTAEDDVVLEKLGQVPAPVILAVNKVDWLEDKSSLLPWLDSISRKREFAAVVPISAKHGTN
VPELEAEIAQRLPESVHYFPEDQITDKSQRFLAAELVREKVMRQLGDELPYQMTVEIEEFKDDGKTLHISALIMVERPGQ
KKILIGERGERIKSIGREARLEMERAFDAKVMLNLWVKVKRGWSDDDRALKSLGYDLD

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=324, Percent_Identity=27.4691358024691, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1788919, Length=295, Percent_Identity=57.2881355932203, Blast_Score=354, Evalue=4e-99,
Organism=Escherichia coli, GI87082120, Length=166, Percent_Identity=34.3373493975904, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646434, Length=302, Percent_Identity=26.4900662251656, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34143; Mature: 34012

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQHCGFVAIVGRPNVGKSTLMNRILGQKISITSRRPQTTRHQVMGIKTEGETQFIYVDT
CCCCCCEEEEECCCCCCHHHHHHHHHCCEEEECCCCCCCCHHHEEEEEECCCEEEEEEEC
PGMHIQTRDRNKAINRFMNQAATHALRDIDCVIFIVDRTKWTAEDDVVLEKLGQVPAPVI
CCCEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCEE
LAVNKVDWLEDKSSLLPWLDSISRKREFAAVVPISAKHGTNVPELEAEIAQRLPESVHYF
EEECCHHHHCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHCHHHHCCC
PEDQITDKSQRFLAAELVREKVMRQLGDELPYQMTVEIEEFKDDGKTLHISALIMVERPG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCEEEEEEEEEEECCC
QKKILIGERGERIKSIGREARLEMERAFDAKVMLNLWVKVKRGWSDDDRALKSLGYDLD
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
TQHCGFVAIVGRPNVGKSTLMNRILGQKISITSRRPQTTRHQVMGIKTEGETQFIYVDT
CCCCCEEEEECCCCCCHHHHHHHHHCCEEEECCCCCCCCHHHEEEEEECCCEEEEEEEC
PGMHIQTRDRNKAINRFMNQAATHALRDIDCVIFIVDRTKWTAEDDVVLEKLGQVPAPVI
CCCEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCEE
LAVNKVDWLEDKSSLLPWLDSISRKREFAAVVPISAKHGTNVPELEAEIAQRLPESVHYF
EEECCHHHHCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHCHHHHCCC
PEDQITDKSQRFLAAELVREKVMRQLGDELPYQMTVEIEEFKDDGKTLHISALIMVERPG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCEEEEEEEEEEECCC
QKKILIGERGERIKSIGREARLEMERAFDAKVMLNLWVKVKRGWSDDDRALKSLGYDLD
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA