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The map label for this gene is lpxK [H]

Identifier: 92113711

GI number: 92113711

Start: 1807982

End: 1808974

Strand: Direct

Name: lpxK [H]

Synonym: Csal_1587

Alternate gene names: 92113711

Gene position: 1807982-1808974 (Clockwise)

Preceding gene: 92113710

Following gene: 92113712

Centisome position: 48.91

GC content: 66.06

Gene sequence:

>993_bases
GTGAGTCGCTTGCAGGATGCCTGGTACCGCGACGCGGCCTGGCTCGTACCGTTGCGTCCCTTGGCGGGGCTCTACGCCCA
GGTCATGAGTGCGCGACGTAGAGCCTATCAGCGTGGCACGAAAAAAGTCTGGACACCCCCGGTGCCGTTGATCGTGATCG
GCAACTTGTCCGTGGGTGGCACCGGCAAGTCACCCCTGGTGGCATGGATGGGGCGCTGGTTACGAGAACGCGGCTGGCAC
CCGGGCATCGTGTCGCGGGGATATGGCGGCCATGCACATCGTTATCCGCTGTACGTCACGCCGGAAACCTCGCCCGTGGA
AGCGGGGGACGAGCCGGTCATGCTCGCGGCGCAGACAGGACTGCCCGTGGCGGTCGACCCTGACCGTCCGCGTGCCGCGC
GCAAGCTGATCGCCGCGGGGTGCGACATCCTGCTCTCCGACGACGGTCTGCAGCACCTGGCGATGGGACGCGACATCGAA
CTGGTGGTCGTGGACGGCGCAAGGGGGTTCGGCAATGGCCGTTGCCTGCCCGCCGGGCCGCTGCGCGAGCCGCTGTCGCG
CCTGCACGAAGTGGATGCGGTGATCGGCAACGGCGCCCTCGCGCAGGATCTTCCCGTGCCTCATCACGGCATGCGCCTGG
TGCCCTCGCGCTGGCGGCATCTGATCGACGATGTCTGCTATCCCATCGAGGGGCGTCCCTTCAATGGCCGTGTGCACGCG
CTGGCGGGCATCGGCCATCCCACGCGGTTTTTCGATACCCTCAAGACGCTGGACGTCGAATTCGATCCCTGTCCGCTGGC
CGATCATCATCGATTCGATGCCGCCGATCTTCAATTTTCCGATAACCGGCCGGTCGTGATGACGGCCAAGGACGCGGTCA
AATGCCGGCCCTTCGCTCATGAACGTTGCTGGGTGCTCGATGTGGAAGCGCATCCCGACGCCGCATTCGTGACATGGCTG
GAGGGCCGCTTGGCGGCGCTGACCGAGAGGTGA

Upstream 100 bases:

>100_bases
TGGAGCAGGGCGAAATCATCGAGAGCGGCACGCATGGCGAACTGTTGGCCCAAGACGGTGCCTATGCGGCGCTTCATCAA
CTGCAATTCCAGGAGGCCGA

Downstream 100 bases:

>100_bases
TGCATGGATAAGGAATTGCTGGCGATGCTGGTCTGCCCCCGCTGTCAGGGCAAGCTGAAGTACGACCGCGAACGTGCGGA
ACTCAAATGCCACTTCGACG

Product: tetraacyldisaccharide 4'-kinase

Products: NA

Alternate protein names: Lipid A 4'-kinase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MSRLQDAWYRDAAWLVPLRPLAGLYAQVMSARRRAYQRGTKKVWTPPVPLIVIGNLSVGGTGKSPLVAWMGRWLRERGWH
PGIVSRGYGGHAHRYPLYVTPETSPVEAGDEPVMLAAQTGLPVAVDPDRPRAARKLIAAGCDILLSDDGLQHLAMGRDIE
LVVVDGARGFGNGRCLPAGPLREPLSRLHEVDAVIGNGALAQDLPVPHHGMRLVPSRWRHLIDDVCYPIEGRPFNGRVHA
LAGIGHPTRFFDTLKTLDVEFDPCPLADHHRFDAADLQFSDNRPVVMTAKDAVKCRPFAHERCWVLDVEAHPDAAFVTWL
EGRLAALTER

Sequences:

>Translated_330_residues
MSRLQDAWYRDAAWLVPLRPLAGLYAQVMSARRRAYQRGTKKVWTPPVPLIVIGNLSVGGTGKSPLVAWMGRWLRERGWH
PGIVSRGYGGHAHRYPLYVTPETSPVEAGDEPVMLAAQTGLPVAVDPDRPRAARKLIAAGCDILLSDDGLQHLAMGRDIE
LVVVDGARGFGNGRCLPAGPLREPLSRLHEVDAVIGNGALAQDLPVPHHGMRLVPSRWRHLIDDVCYPIEGRPFNGRVHA
LAGIGHPTRFFDTLKTLDVEFDPCPLADHHRFDAADLQFSDNRPVVMTAKDAVKCRPFAHERCWVLDVEAHPDAAFVTWL
EGRLAALTER
>Mature_329_residues
SRLQDAWYRDAAWLVPLRPLAGLYAQVMSARRRAYQRGTKKVWTPPVPLIVIGNLSVGGTGKSPLVAWMGRWLRERGWHP
GIVSRGYGGHAHRYPLYVTPETSPVEAGDEPVMLAAQTGLPVAVDPDRPRAARKLIAAGCDILLSDDGLQHLAMGRDIEL
VVVDGARGFGNGRCLPAGPLREPLSRLHEVDAVIGNGALAQDLPVPHHGMRLVPSRWRHLIDDVCYPIEGRPFNGRVHAL
AGIGHPTRFFDTLKTLDVEFDPCPLADHHRFDAADLQFSDNRPVVMTAKDAVKCRPFAHERCWVLDVEAHPDAAFVTWLE
GRLAALTER

Specific function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) [H]

COG id: COG1663

COG function: function code M; Tetraacyldisaccharide-1-P 4'-kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxK family [H]

Homologues:

Organism=Escherichia coli, GI1787144, Length=313, Percent_Identity=44.408945686901, Blast_Score=244, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003758 [H]

Pfam domain/function: PF02606 LpxK [H]

EC number: =2.7.1.130 [H]

Molecular weight: Translated: 36462; Mature: 36331

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLQDAWYRDAAWLVPLRPLAGLYAQVMSARRRAYQRGTKKVWTPPVPLIVIGNLSVGG
CCCHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEECEEECC
TGKSPLVAWMGRWLRERGWHPGIVSRGYGGHAHRYPLYVTPETSPVEAGDEPVMLAAQTG
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECCC
LPVAVDPDRPRAARKLIAAGCDILLSDDGLQHLAMGRDIELVVVDGARGFGNGRCLPAGP
CEEEECCCCCHHHHHHHHHCCCEEECCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCH
LREPLSRLHEVDAVIGNGALAQDLPVPHHGMRLVPSRWRHLIDDVCYPIEGRPFNGRVHA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEE
LAGIGHPTRFFDTLKTLDVEFDPCPLADHHRFDAADLQFSDNRPVVMTAKDAVKCRPFAH
EECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCEECCCCCC
ERCWVLDVEAHPDAAFVTWLEGRLAALTER
CCEEEEEEECCCCCEEEEEHHCHHHHHCCC
>Mature Secondary Structure 
SRLQDAWYRDAAWLVPLRPLAGLYAQVMSARRRAYQRGTKKVWTPPVPLIVIGNLSVGG
CCHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEECEEECC
TGKSPLVAWMGRWLRERGWHPGIVSRGYGGHAHRYPLYVTPETSPVEAGDEPVMLAAQTG
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECCC
LPVAVDPDRPRAARKLIAAGCDILLSDDGLQHLAMGRDIELVVVDGARGFGNGRCLPAGP
CEEEECCCCCHHHHHHHHHCCCEEECCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCH
LREPLSRLHEVDAVIGNGALAQDLPVPHHGMRLVPSRWRHLIDDVCYPIEGRPFNGRVHA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEE
LAGIGHPTRFFDTLKTLDVEFDPCPLADHHRFDAADLQFSDNRPVVMTAKDAVKCRPFAH
EECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCEECCCCCC
ERCWVLDVEAHPDAAFVTWLEGRLAALTER
CCEEEEEEECCCCCEEEEEHHCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA