| Definition | Chromohalobacter salexigens DSM 3043 chromosome, complete genome. |
|---|---|
| Accession | NC_007963 |
| Length | 3,696,649 |
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The map label for this gene is sdh [H]
Identifier: 92112296
GI number: 92112296
Start: 184763
End: 185524
Strand: Direct
Name: sdh [H]
Synonym: Csal_0161
Alternate gene names: 92112296
Gene position: 184763-185524 (Clockwise)
Preceding gene: 92112295
Following gene: 92112298
Centisome position: 5.0
GC content: 65.88
Gene sequence:
>762_bases ATGACGGATTGTGTCTTCATCACCGGTGCGACGTCCGGGTTCGGCCGCGCCGCTGCGCATCGCTTTGCTGCCGCGGGCTG GTCGCTGGTGCTCACCGGGCGGCGTCTCGAGCGCCTGGAAGCCTTGAAGGAAGAGCTCCAGGGGCGGGTACCGGTGCATA TCATCGCCCTCGACGTGCGCGACAGCGACGTCGTGGATGCCGCCGTGGCCGCGTTGCCGGAAGGCTTCACGCGGGTGCGC ACGCTGCTCAACAACGCTGGCCTCGCGTTGGCGCCGCAGTCCGCCCAACACACCGACCGGAGCGACTGGCACACCATGAT CGATACCAACGTCACGGGGCTGGTCAATGTCACCCATGCGTTGCTGCCCACACTGATCGACGTCGGCGAGGGCGCCACCA TCGTCAATGTCGGCTCCATCGCCGGCCAATGGCCGTATCCTGGCAGCCACGTCTATGGCGCCTCCAAGGCCTTCGTCAAA CAGTTCAGCTACAACCTGCGCTGCGACCTGCTCGGCACCGGCGTGCGCGTGACCGACCTCGCGCCCGGCATTGCCGAGAC CGAATTCACCCTCGTGCGCACCGGCGGCGACCAGGCCGCCTCCGACGCGCTGTATCGCGGCACCACTGCGCTCACTGCCG AGGATATCGCCGAGCAGATGTTCTATATCGCCACACTCCCGCCGCATGTCAACTTCAATCGGTTGGAAGTCATGCCCACG CGCCAGGCCTGGTCCGCGTTTGCCATCGATTACGATGCGTGA
Upstream 100 bases:
>100_bases TTCAGCGTCGCGCCACTGTTGATCGCGCTCTCGCTGTGGGTACTGCTTCGCGAGGCGATTGGCTGACGCGTCATCATCAT CACGACAAGAGGAAATCGGC
Downstream 100 bases:
>100_bases GGGAAAAGCGCCGAGCTCCGATCGTGAGACCGGAGCAGGCTGCCTATCGGGCTATCTCAGGTGCAGGCGGAGTTGCCCCA GCGCTCGAGCAGCATGTCGA
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 253; Mature: 252
Protein sequence:
>253_residues MTDCVFITGATSGFGRAAAHRFAAAGWSLVLTGRRLERLEALKEELQGRVPVHIIALDVRDSDVVDAAVAALPEGFTRVR TLLNNAGLALAPQSAQHTDRSDWHTMIDTNVTGLVNVTHALLPTLIDVGEGATIVNVGSIAGQWPYPGSHVYGASKAFVK QFSYNLRCDLLGTGVRVTDLAPGIAETEFTLVRTGGDQAASDALYRGTTALTAEDIAEQMFYIATLPPHVNFNRLEVMPT RQAWSAFAIDYDA
Sequences:
>Translated_253_residues MTDCVFITGATSGFGRAAAHRFAAAGWSLVLTGRRLERLEALKEELQGRVPVHIIALDVRDSDVVDAAVAALPEGFTRVR TLLNNAGLALAPQSAQHTDRSDWHTMIDTNVTGLVNVTHALLPTLIDVGEGATIVNVGSIAGQWPYPGSHVYGASKAFVK QFSYNLRCDLLGTGVRVTDLAPGIAETEFTLVRTGGDQAASDALYRGTTALTAEDIAEQMFYIATLPPHVNFNRLEVMPT RQAWSAFAIDYDA >Mature_252_residues TDCVFITGATSGFGRAAAHRFAAAGWSLVLTGRRLERLEALKEELQGRVPVHIIALDVRDSDVVDAAVAALPEGFTRVRT LLNNAGLALAPQSAQHTDRSDWHTMIDTNVTGLVNVTHALLPTLIDVGEGATIVNVGSIAGQWPYPGSHVYGASKAFVKQ FSYNLRCDLLGTGVRVTDLAPGIAETEFTLVRTGGDQAASDALYRGTTALTAEDIAEQMFYIATLPPHVNFNRLEVMPTR QAWSAFAIDYDA
Specific function: Catalyzes the oxidation of the hydroxyl group of serine to form 2-aminomalonate semialdehyde which is spontaneously converted into 2-aminoacetaldehyde and CO(2). Also acts on D- serine, L-glycerate, D-glycerate and 2-methyl-DL-serine. Does not act on O-me
COG id: COG4221
COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=36.5979381443299, Blast_Score=95, Evalue=7e-20, Organism=Homo sapiens, GI109715829, Length=245, Percent_Identity=27.3469387755102, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI7706318, Length=259, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI19923817, Length=186, Percent_Identity=27.9569892473118, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI7705855, Length=192, Percent_Identity=28.125, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI150247226, Length=188, Percent_Identity=32.9787234042553, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI119392083, Length=194, Percent_Identity=29.8969072164948, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI4557649, Length=191, Percent_Identity=31.413612565445, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI40254992, Length=191, Percent_Identity=31.413612565445, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI40548397, Length=195, Percent_Identity=32.3076923076923, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI214010158, Length=195, Percent_Identity=32.3076923076923, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI214010156, Length=195, Percent_Identity=32.3076923076923, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI22758144, Length=195, Percent_Identity=32.3076923076923, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI226371731, Length=194, Percent_Identity=25.2577319587629, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI31542939, Length=190, Percent_Identity=27.8947368421053, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787820, Length=246, Percent_Identity=47.5609756097561, Blast_Score=233, Evalue=8e-63, Organism=Escherichia coli, GI87082100, Length=185, Percent_Identity=35.1351351351351, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1787335, Length=185, Percent_Identity=27.5675675675676, Blast_Score=71, Evalue=9e-14, Organism=Escherichia coli, GI2367175, Length=191, Percent_Identity=27.2251308900524, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI87082160, Length=191, Percent_Identity=29.8429319371728, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI1786812, Length=185, Percent_Identity=30.2702702702703, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1786701, Length=194, Percent_Identity=28.8659793814433, Blast_Score=63, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71994604, Length=232, Percent_Identity=31.0344827586207, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI71994600, Length=233, Percent_Identity=30.0429184549356, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560332, Length=245, Percent_Identity=31.0204081632653, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562990, Length=209, Percent_Identity=33.9712918660287, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17562904, Length=206, Percent_Identity=32.0388349514563, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17560150, Length=209, Percent_Identity=33.9712918660287, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17562908, Length=193, Percent_Identity=35.2331606217617, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI72000259, Length=237, Percent_Identity=30.8016877637131, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17565030, Length=225, Percent_Identity=30.2222222222222, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17563726, Length=192, Percent_Identity=33.8541666666667, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562910, Length=192, Percent_Identity=30.2083333333333, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17538480, Length=209, Percent_Identity=30.622009569378, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI193204405, Length=198, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17562906, Length=193, Percent_Identity=33.160621761658, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17559104, Length=193, Percent_Identity=31.6062176165803, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538486, Length=199, Percent_Identity=28.643216080402, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17551412, Length=212, Percent_Identity=27.8301886792453, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560220, Length=192, Percent_Identity=30.7291666666667, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17531453, Length=188, Percent_Identity=33.5106382978723, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17544670, Length=243, Percent_Identity=26.3374485596708, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71997402, Length=172, Percent_Identity=35.4651162790698, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560676, Length=194, Percent_Identity=28.3505154639175, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17561402, Length=201, Percent_Identity=27.363184079602, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI25152911, Length=204, Percent_Identity=27.4509803921569, Blast_Score=64, Evalue=1e-10, Organism=Saccharomyces cerevisiae, GI6323882, Length=245, Percent_Identity=37.5510204081633, Blast_Score=165, Evalue=6e-42, Organism=Saccharomyces cerevisiae, GI6319635, Length=203, Percent_Identity=27.0935960591133, Blast_Score=72, Evalue=9e-14, Organism=Saccharomyces cerevisiae, GI6322227, Length=196, Percent_Identity=27.0408163265306, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI116007236, Length=249, Percent_Identity=30.9236947791165, Blast_Score=107, Evalue=6e-24, Organism=Drosophila melanogaster, GI23397609, Length=188, Percent_Identity=35.6382978723404, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI21357041, Length=199, Percent_Identity=35.1758793969849, Blast_Score=98, Evalue=5e-21, Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=30.2083333333333, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI24640442, Length=225, Percent_Identity=29.7777777777778, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI28571526, Length=188, Percent_Identity=32.4468085106383, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24643142, Length=188, Percent_Identity=32.4468085106383, Blast_Score=87, Evalue=2e-17, Organism=Drosophila melanogaster, GI24641232, Length=244, Percent_Identity=28.2786885245902, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI116007234, Length=246, Percent_Identity=29.6747967479675, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI24644339, Length=188, Percent_Identity=29.7872340425532, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI161076933, Length=196, Percent_Identity=30.6122448979592, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI24584748, Length=196, Percent_Identity=30.6122448979592, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI28571387, Length=239, Percent_Identity=27.1966527196653, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24648944, Length=242, Percent_Identity=25.6198347107438, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI28574402, Length=190, Percent_Identity=30.5263157894737, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24584744, Length=190, Percent_Identity=30.5263157894737, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI116007238, Length=195, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI24580925, Length=201, Percent_Identity=29.8507462686567, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI281364494, Length=243, Percent_Identity=24.6913580246914, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24663911, Length=243, Percent_Identity=25.1028806584362, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24584752, Length=193, Percent_Identity=27.4611398963731, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI17737361, Length=193, Percent_Identity=29.5336787564767, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24648693, Length=244, Percent_Identity=25.8196721311475, Blast_Score=64, Evalue=1e-10, Organism=Drosophila melanogaster, GI21355889, Length=244, Percent_Identity=25.8196721311475, Blast_Score=64, Evalue=1e-10,
Paralogues:
None
Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.276 [H]
Molecular weight: Translated: 27183; Mature: 27052
Theoretical pI: Translated: 5.26; Mature: 5.26
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTDCVFITGATSGFGRAAAHRFAAAGWSLVLTGRRLERLEALKEELQGRVPVHIIALDVR CCCEEEEEECCCCCHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHCCCCCEEEEEEECC DSDVVDAAVAALPEGFTRVRTLLNNAGLALAPQSAQHTDRSDWHTMIDTNVTGLVNVTHA CCHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEECCCCHHHHHHHHH LLPTLIDVGEGATIVNVGSIAGQWPYPGSHVYGASKAFVKQFSYNLRCDLLGTGVRVTDL HHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCEEEEEC APGIAETEFTLVRTGGDQAASDALYRGTTALTAEDIAEQMFYIATLPPHVNFNRLEVMPT CCCCCCCEEEEEEECCCHHHHHHHHCCCCEECHHHHHHHEEEEEECCCCCCCCEEEEEEC RQAWSAFAIDYDA HHCCEEEEEEECC >Mature Secondary Structure TDCVFITGATSGFGRAAAHRFAAAGWSLVLTGRRLERLEALKEELQGRVPVHIIALDVR CCEEEEEECCCCCHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHCCCCCEEEEEEECC DSDVVDAAVAALPEGFTRVRTLLNNAGLALAPQSAQHTDRSDWHTMIDTNVTGLVNVTHA CCHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEECCCCHHHHHHHHH LLPTLIDVGEGATIVNVGSIAGQWPYPGSHVYGASKAFVKQFSYNLRCDLLGTGVRVTDL HHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCEEEEEC APGIAETEFTLVRTGGDQAASDALYRGTTALTAEDIAEQMFYIATLPPHVNFNRLEVMPT CCCCCCCEEEEEEECCCHHHHHHHHCCCCEECHHHHHHHEEEEEECCCCCCCCEEEEEEC RQAWSAFAIDYDA HHCCEEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11743193; 11743194 [H]