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The map label for this gene is gntR [H]

Identifier: 91790359

GI number: 91790359

Start: 4786821

End: 4787852

Strand: Reverse

Name: gntR [H]

Synonym: Bpro_4527

Alternate gene names: 91790359

Gene position: 4787852-4786821 (Counterclockwise)

Preceding gene: 91790362

Following gene: 91790358

Centisome position: 92.07

GC content: 67.73

Gene sequence:

>1032_bases
ATGGATTCCCTGAAAAAGCCAGGCCGGGCCGCCAGGCCAGGCACGGGCGGCATCACGCTCAATGATGTGGCCAAGCTTGC
CGGCGTGTCGGCCATTACCGTTTCGCGCGCCCTCAACACGCCCGCCGCCGTGTCGCCCGACACGCTGGAGCGCGTGCGCG
GCGCGATCGCGCGCAGCGGTTATGTGCCCAATCTTGTCGCGGGCGGACTGGCATCGAACCGGAGCCGGCTGGTGGCTGCG
CTGGTGCCGACGATCGCCGGACCGGTGTTTCTGGAAACCATCCAGGCGCTGACCGATGCCCTCGCCGAGGCTGGCTGCCA
GCTGATGCTGGGCCAGAGCGGCTATGGCGGCGCGCGGGAAGACGCCCTGCTGGACGCCATCATCGGGCGCCGGCCCGACG
GCATCGTGCTGATCGGCATCATGCACTCCGCCGAAGGGCGGCGGCGCCTGCTGGCGTCCGGCATACCTGTGGTTGAAACC
TGGGACATCACGCCCACGCCGCTCGACATGATTGTGGGATTTTCCCACGAGAAAGTGGGCGCCGCGGTGGCCGATTACCT
TCATGGGCGAGGCTTTCACCGGCCCGGCATCGTCAGTGCCAGCGATGAGCGCGCGACGCGGCGCCGGGTCGGATTCGAGC
AGCGTTTTGCCGAGCTGGGTGTGCCGGGCATTCCGGCGTGTGTGGTGCCGTCGCCGTCTTCGCTTGGCAACGGGCGGGCC
GGATTTGCCGAGCTGCGCGCCAGCCATCCCGGCCTTGACGTGGTGTTTTGCAGCTCCGACGTGATTGCCCATGGCGTCAT
CACCGAGGCCCACGCCACCGGGCTGCGCGTGCCGGAAGATATCGCCGTGATGGGCTTTGGCGACCTGCCGTTCGCCGCCT
TCACCTATCCGCAACTGAGCACCGTAAGCATCGACGGCACCGCCATCGGCCGGCAGGCCGCCAACTTCATTCTGGACCGG
GTGGCAAACCGCGATGTCGGCCCCCCGGTGCGCGATATCGGGTTTTCCATCATCCAAAGAGGCAGCGCCTGA

Upstream 100 bases:

>100_bases
TGCGGCATGTTCAGGGTTGCCGTCACCGCCTGCGCCACGTATCTCCCCTGGCGCTGGGCCAGCAGTCAAGGTCCGTGCAA
GTTAGCGTTAACATCAGCGC

Downstream 100 bases:

>100_bases
CCTGAGTGCGCCAGGTTCGTGTTTTATAATAAATTGTTAGCGCTAACATTCTGTTTTTCGGCGCATCTATCTTGTTGCCT
GTATGCAACGCTCTTCATAA

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MDSLKKPGRAARPGTGGITLNDVAKLAGVSAITVSRALNTPAAVSPDTLERVRGAIARSGYVPNLVAGGLASNRSRLVAA
LVPTIAGPVFLETIQALTDALAEAGCQLMLGQSGYGGAREDALLDAIIGRRPDGIVLIGIMHSAEGRRRLLASGIPVVET
WDITPTPLDMIVGFSHEKVGAAVADYLHGRGFHRPGIVSASDERATRRRVGFEQRFAELGVPGIPACVVPSPSSLGNGRA
GFAELRASHPGLDVVFCSSDVIAHGVITEAHATGLRVPEDIAVMGFGDLPFAAFTYPQLSTVSIDGTAIGRQAANFILDR
VANRDVGPPVRDIGFSIIQRGSA

Sequences:

>Translated_343_residues
MDSLKKPGRAARPGTGGITLNDVAKLAGVSAITVSRALNTPAAVSPDTLERVRGAIARSGYVPNLVAGGLASNRSRLVAA
LVPTIAGPVFLETIQALTDALAEAGCQLMLGQSGYGGAREDALLDAIIGRRPDGIVLIGIMHSAEGRRRLLASGIPVVET
WDITPTPLDMIVGFSHEKVGAAVADYLHGRGFHRPGIVSASDERATRRRVGFEQRFAELGVPGIPACVVPSPSSLGNGRA
GFAELRASHPGLDVVFCSSDVIAHGVITEAHATGLRVPEDIAVMGFGDLPFAAFTYPQLSTVSIDGTAIGRQAANFILDR
VANRDVGPPVRDIGFSIIQRGSA
>Mature_343_residues
MDSLKKPGRAARPGTGGITLNDVAKLAGVSAITVSRALNTPAAVSPDTLERVRGAIARSGYVPNLVAGGLASNRSRLVAA
LVPTIAGPVFLETIQALTDALAEAGCQLMLGQSGYGGAREDALLDAIIGRRPDGIVLIGIMHSAEGRRRLLASGIPVVET
WDITPTPLDMIVGFSHEKVGAAVADYLHGRGFHRPGIVSASDERATRRRVGFEQRFAELGVPGIPACVVPSPSSLGNGRA
GFAELRASHPGLDVVFCSSDVIAHGVITEAHATGLRVPEDIAVMGFGDLPFAAFTYPQLSTVSIDGTAIGRQAANFILDR
VANRDVGPPVRDIGFSIIQRGSA

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=325, Percent_Identity=30.7692307692308, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790369, Length=338, Percent_Identity=29.585798816568, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1790715, Length=327, Percent_Identity=28.7461773700306, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1787948, Length=333, Percent_Identity=27.6276276276276, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790194, Length=333, Percent_Identity=26.7267267267267, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1788474, Length=298, Percent_Identity=28.8590604026846, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789068, Length=329, Percent_Identity=25.2279635258359, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789202, Length=287, Percent_Identity=25.4355400696864, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787906, Length=253, Percent_Identity=28.0632411067194, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786540, Length=313, Percent_Identity=25.2396166134185, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789456, Length=145, Percent_Identity=28.2758620689655, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787580, Length=320, Percent_Identity=22.5, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35618; Mature: 35618

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2 ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLKKPGRAARPGTGGITLNDVAKLAGVSAITVSRALNTPAAVSPDTLERVRGAIARSG
CCCCCCCCCCCCCCCCCEEHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
YVPNLVAGGLASNRSRLVAALVPTIAGPVFLETIQALTDALAEAGCQLMLGQSGYGGARE
CCCHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHH
DALLDAIIGRRPDGIVLIGIMHSAEGRRRLLASGIPVVETWDITPTPLDMIVGFSHEKVG
HHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHCCCCEEEECCCCCCCHHHHCCCCCHHHH
AAVADYLHGRGFHRPGIVSASDERATRRRVGFEQRFAELGVPGIPACVVPSPSSLGNGRA
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCEEECCCCCCCCCCCC
GFAELRASHPGLDVVFCSSDVIAHGVITEAHATGLRVPEDIAVMGFGDLPFAAFTYPQLS
CHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHCCCCCCE
TVSIDGTAIGRQAANFILDRVANRDVGPPVRDIGFSIIQRGSA
EEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MDSLKKPGRAARPGTGGITLNDVAKLAGVSAITVSRALNTPAAVSPDTLERVRGAIARSG
CCCCCCCCCCCCCCCCCEEHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
YVPNLVAGGLASNRSRLVAALVPTIAGPVFLETIQALTDALAEAGCQLMLGQSGYGGARE
CCCHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHH
DALLDAIIGRRPDGIVLIGIMHSAEGRRRLLASGIPVVETWDITPTPLDMIVGFSHEKVG
HHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHCCCCEEEECCCCCCCHHHHCCCCCHHHH
AAVADYLHGRGFHRPGIVSASDERATRRRVGFEQRFAELGVPGIPACVVPSPSSLGNGRA
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCEEECCCCCCCCCCCC
GFAELRASHPGLDVVFCSSDVIAHGVITEAHATGLRVPEDIAVMGFGDLPFAAFTYPQLS
CHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHCCCCCCE
TVSIDGTAIGRQAANFILDRVANRDVGPPVRDIGFSIIQRGSA
EEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]