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The map label for this gene is argS

Identifier: 91790322

GI number: 91790322

Start: 4744083

End: 4745768

Strand: Reverse

Name: argS

Synonym: Bpro_4490

Alternate gene names: 91790322

Gene position: 4745768-4744083 (Counterclockwise)

Preceding gene: 91790323

Following gene: 91790321

Centisome position: 91.26

GC content: 64.0

Gene sequence:

>1686_bases
ATGCTTCAAATCAAACAAGACTTGCTGGACGCGCTGGGCCAGGCCCTCAAAACCATGGCGCCTGACAGTGGCGTGGCGGC
CGTGTTCGAGTCGCCCAAGGTGGCGGCGCACGGTGATTTCGCCTCCACCGCGGCCATGCAGCTGGCCAAACCGCTCAAGC
TCAACCCCCGCCAGGTGGCGGAAAACCTGCGCGGGCTGCTGCTCCAGGCGCCCGCGTTTGCGCGCTGGGTGGACGCGATT
GAAATCGCCGGCCCGGGTTTTCTCAATATCCGGCTCAAGCCCGAAGCCAAGCAGCAGGTGGTGCGGGAAGTGCTGCAGGG
TGCAGACCAGTACGGCATGCAATTGGCCGACAGCCCGCACCGCATGGTTGTGGAGTTCGTCTCGGCCAACCCGACCGGGC
CGCTGCACGTGGGCCATGGCCGCCAGGCGGCGCTGGGCGACGCGATCTGCAACCTGTTTGACACGCAGGGCTGGGATGTG
TGGCGCGAGTTTTATTACAACGACGCCGGCGTGCAGATCCAGACCCTGGCCACCAGCACGCAGGCGCGCGCCAAAGGCCT
CAAACCGGGCGATGCCGGCTGGCCCGAGCCTGCCTACAACGGTGACTACATTGCCGACATTGCCAATGATTTTCTGGCCA
AAAAGACCGTCAAATCCGACGACCGGGAGTTCACCGCCAGCGGTGACGTCGAAGACATCGATGCCATCCGCCAGTTTGCC
GTGGCCTATTTGCGCCATGAGCAGGACCTGGACCTGCGGGCCTTCTCGGTCCGGTTTGACAACTACTACCTCGAGTCCAG
CCTGTACAGCTCGGGCCGGGTCGACAGCGCGGTGCAAAAACTCAAGGACGCCGGCAAAACCTACGAGCAGGACGGCGCGC
TGTGGCTCAAGTCGACCGATTACGGCGACGACAAAGACCGCGTGATGAAAAAGGGCGACGGCAGCTACACCTATTTTGTG
CCTGACGTGGCCTACCACCTGGCCAAATGGGAGCGCGGTTTCAGCAAGGCCATCAACATCCAGGGCATGGACCACCACGG
CACGATTGCCCGCGTGCGCGCCGGGCTGCAGGCCGCCAGCGCCGGCATTCCGCAGGGCTACCCCGACTACGTGCTGCACA
CCATGGTGCGCGTCGTGCGCCATGGCGAAGAGGTCAAGATCTCCAAGCGCGCCGGCAGCTACGTCACGCTGCGCGACCTG
ATCGAGTGGACCAGCGCGGATGCCGTGCGCTTCTTCCTGCTCAGCCGCAAGCCCGACACCGAGTACGTGTTTGACATTGA
CCTGGCACTGGCCAAAAACAATGAAAACCCGGTGTACTACGTGCAATACGCCCATGCCCGCATCTGCTCGATTCTCGGCA
CCTGGGCTGCCCAGGGCGGTGATGCGAGCCAGCTGAAAAGCGTGGATCTGTCAGCGCTGGACGGCCCGCAGGCCCAGGCA
CTCATGCTGCTGCTGGCCAAGTACCCCGACATGCTCAGCAATGCCGCCGCCGGGCTGGCGCCGCACGACGTGGCCTTTTA
CCTGCGCGAGCTGGCCGCCTGCTACCACAGCTATTACGACGCCGAACGGATTCTGGTGGACGACGAAGCCATCAAGCTGG
CGCGCCTGGCGCTGGTCGCCGCGACGGCGCAGGTGTTGCACAATGGCCTCAAGGTGCTGGGCGTCAGTGCGCCCCACAAA
ATGTAG

Upstream 100 bases:

>100_bases
CATGGCGCGCTCCTCTCGCTGCCCCCGCTTCTGTCCGGCCAAAGGGGCGGCGCTTGTCACACAGGGAAAAGGGTGAGTGC
CGCGCCCCTAAAATCTCCCC

Downstream 100 bases:

>100_bases
GCAACCATGAAGCACACGCAGCGGGATTCAGAGCTGGATTCAGAGACAGGCAAGAAAATTGGGCAAGGCATGAGAAAACA
ACGAGGCGGAACCCTGCTGG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MLQIKQDLLDALGQALKTMAPDSGVAAVFESPKVAAHGDFASTAAMQLAKPLKLNPRQVAENLRGLLLQAPAFARWVDAI
EIAGPGFLNIRLKPEAKQQVVREVLQGADQYGMQLADSPHRMVVEFVSANPTGPLHVGHGRQAALGDAICNLFDTQGWDV
WREFYYNDAGVQIQTLATSTQARAKGLKPGDAGWPEPAYNGDYIADIANDFLAKKTVKSDDREFTASGDVEDIDAIRQFA
VAYLRHEQDLDLRAFSVRFDNYYLESSLYSSGRVDSAVQKLKDAGKTYEQDGALWLKSTDYGDDKDRVMKKGDGSYTYFV
PDVAYHLAKWERGFSKAINIQGMDHHGTIARVRAGLQAASAGIPQGYPDYVLHTMVRVVRHGEEVKISKRAGSYVTLRDL
IEWTSADAVRFFLLSRKPDTEYVFDIDLALAKNNENPVYYVQYAHARICSILGTWAAQGGDASQLKSVDLSALDGPQAQA
LMLLLAKYPDMLSNAAAGLAPHDVAFYLRELAACYHSYYDAERILVDDEAIKLARLALVAATAQVLHNGLKVLGVSAPHK
M

Sequences:

>Translated_561_residues
MLQIKQDLLDALGQALKTMAPDSGVAAVFESPKVAAHGDFASTAAMQLAKPLKLNPRQVAENLRGLLLQAPAFARWVDAI
EIAGPGFLNIRLKPEAKQQVVREVLQGADQYGMQLADSPHRMVVEFVSANPTGPLHVGHGRQAALGDAICNLFDTQGWDV
WREFYYNDAGVQIQTLATSTQARAKGLKPGDAGWPEPAYNGDYIADIANDFLAKKTVKSDDREFTASGDVEDIDAIRQFA
VAYLRHEQDLDLRAFSVRFDNYYLESSLYSSGRVDSAVQKLKDAGKTYEQDGALWLKSTDYGDDKDRVMKKGDGSYTYFV
PDVAYHLAKWERGFSKAINIQGMDHHGTIARVRAGLQAASAGIPQGYPDYVLHTMVRVVRHGEEVKISKRAGSYVTLRDL
IEWTSADAVRFFLLSRKPDTEYVFDIDLALAKNNENPVYYVQYAHARICSILGTWAAQGGDASQLKSVDLSALDGPQAQA
LMLLLAKYPDMLSNAAAGLAPHDVAFYLRELAACYHSYYDAERILVDDEAIKLARLALVAATAQVLHNGLKVLGVSAPHK
M
>Mature_561_residues
MLQIKQDLLDALGQALKTMAPDSGVAAVFESPKVAAHGDFASTAAMQLAKPLKLNPRQVAENLRGLLLQAPAFARWVDAI
EIAGPGFLNIRLKPEAKQQVVREVLQGADQYGMQLADSPHRMVVEFVSANPTGPLHVGHGRQAALGDAICNLFDTQGWDV
WREFYYNDAGVQIQTLATSTQARAKGLKPGDAGWPEPAYNGDYIADIANDFLAKKTVKSDDREFTASGDVEDIDAIRQFA
VAYLRHEQDLDLRAFSVRFDNYYLESSLYSSGRVDSAVQKLKDAGKTYEQDGALWLKSTDYGDDKDRVMKKGDGSYTYFV
PDVAYHLAKWERGFSKAINIQGMDHHGTIARVRAGLQAASAGIPQGYPDYVLHTMVRVVRHGEEVKISKRAGSYVTLRDL
IEWTSADAVRFFLLSRKPDTEYVFDIDLALAKNNENPVYYVQYAHARICSILGTWAAQGGDASQLKSVDLSALDGPQAQA
LMLLLAKYPDMLSNAAAGLAPHDVAFYLRELAACYHSYYDAERILVDDEAIKLARLALVAATAQVLHNGLKVLGVSAPHK
M

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=630, Percent_Identity=24.1269841269841, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1788184, Length=587, Percent_Identity=25.7240204429302, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71985061, Length=590, Percent_Identity=24.406779661017, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71985068, Length=555, Percent_Identity=23.963963963964, Blast_Score=92, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6320548, Length=525, Percent_Identity=25.1428571428571, Blast_Score=126, Evalue=8e-30,
Organism=Drosophila melanogaster, GI18859963, Length=626, Percent_Identity=23.1629392971246, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_POLSJ (Q123B6)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_551274.1
- ProteinModelPortal:   Q123B6
- STRING:   Q123B6
- GeneID:   4012843
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_4490
- NMPDR:   fig|296591.1.peg.1090
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   ETIRGCL
- ProtClustDB:   PRK01611
- BioCyc:   PSP296591:BPRO_4490-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 61674; Mature: 61674

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQIKQDLLDALGQALKTMAPDSGVAAVFESPKVAAHGDFASTAAMQLAKPLKLNPRQVA
CCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEECCCHHHHHHHHHHCCCCCCHHHHH
ENLRGLLLQAPAFARWVDAIEIAGPGFLNIRLKPEAKQQVVREVLQGADQYGMQLADSPH
HHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCHHHCCCCCCCCH
RMVVEFVSANPTGPLHVGHGRQAALGDAICNLFDTQGWDVWREFYYNDAGVQIQTLATST
HHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCH
QARAKGLKPGDAGWPEPAYNGDYIADIANDFLAKKTVKSDDREFTASGDVEDIDAIRQFA
HHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
VAYLRHEQDLDLRAFSVRFDNYYLESSLYSSGRVDSAVQKLKDAGKTYEQDGALWLKSTD
HHHHHCCCCCCEEEEEEEECCEEEHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCC
YGDDKDRVMKKGDGSYTYFVPDVAYHLAKWERGFSKAINIQGMDHHGTIARVRAGLQAAS
CCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHH
AGIPQGYPDYVLHTMVRVVRHGEEVKISKRAGSYVTLRDLIEWTSADAVRFFLLSRKPDT
CCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHCCCHHEEEEEECCCCCC
EYVFDIDLALAKNNENPVYYVQYAHARICSILGTWAAQGGDASQLKSVDLSALDGPQAQA
CEEEEEEEEEEECCCCCEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHH
LMLLLAKYPDMLSNAAAGLAPHDVAFYLRELAACYHSYYDAERILVDDEAIKLARLALVA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHH
ATAQVLHNGLKVLGVSAPHKM
HHHHHHHCCHHEEECCCCCCC
>Mature Secondary Structure
MLQIKQDLLDALGQALKTMAPDSGVAAVFESPKVAAHGDFASTAAMQLAKPLKLNPRQVA
CCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEECCCHHHHHHHHHHCCCCCCHHHHH
ENLRGLLLQAPAFARWVDAIEIAGPGFLNIRLKPEAKQQVVREVLQGADQYGMQLADSPH
HHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCHHHCCCCCCCCH
RMVVEFVSANPTGPLHVGHGRQAALGDAICNLFDTQGWDVWREFYYNDAGVQIQTLATST
HHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCH
QARAKGLKPGDAGWPEPAYNGDYIADIANDFLAKKTVKSDDREFTASGDVEDIDAIRQFA
HHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
VAYLRHEQDLDLRAFSVRFDNYYLESSLYSSGRVDSAVQKLKDAGKTYEQDGALWLKSTD
HHHHHCCCCCCEEEEEEEECCEEEHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCC
YGDDKDRVMKKGDGSYTYFVPDVAYHLAKWERGFSKAINIQGMDHHGTIARVRAGLQAAS
CCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHH
AGIPQGYPDYVLHTMVRVVRHGEEVKISKRAGSYVTLRDLIEWTSADAVRFFLLSRKPDT
CCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHCCCHHEEEEEECCCCCC
EYVFDIDLALAKNNENPVYYVQYAHARICSILGTWAAQGGDASQLKSVDLSALDGPQAQA
CEEEEEEEEEEECCCCCEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHH
LMLLLAKYPDMLSNAAAGLAPHDVAFYLRELAACYHSYYDAERILVDDEAIKLARLALVA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHH
ATAQVLHNGLKVLGVSAPHKM
HHHHHHHCCHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA