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The map label for this gene is ndh [H]

Identifier: 91789310

GI number: 91789310

Start: 3660336

End: 3661658

Strand: Direct

Name: ndh [H]

Synonym: Bpro_3455

Alternate gene names: 91789310

Gene position: 3660336-3661658 (Clockwise)

Preceding gene: 91789309

Following gene: 91789311

Centisome position: 70.39

GC content: 65.08

Gene sequence:

>1323_bases
ATGCAACGCATCGTCATCGTCGGCGGGGGCGCGGGAGGGCTGGCCCTGGCGACCCAACTGGGCAAGCGCCTGGGCAAAAA
AGGGCTGGCCGAGATCACCCTGGTGGATGCGGCGCGCACCCATGTCTGGAAGCCACTGCTGCACCAGCTGGCTGCAGGCA
GCTTTGACACGCATGCCGAAGAAATCGAATACCTGGCGCAGGCCCGCTGGAACCACTTCAAGTTCCGGCTCGGCAGCCTG
GTCGGCATTGACCGTCACAGCAAAACCCTGCAGCTGGCCGCCAGCCATGACGCAGCGGGCCGCGAGATCACGCCAGCCCA
ACAACTGGGCTACGACACGCTGGTGATTGCAGTGGGCAGCCAGACCAACGACTTCGGCACACTCGGCGCTGCCGAGCACA
CCATCAAGCTGGACAGCCCGCAAGCGGCCCAGCACTTCAACGACCGCCTGATCAACGCCTTCATTCGCGCGCAAACCGTG
CCGCGCACGGCCGGCAGCGGGCGCCTGACGGTGGCGATCGTGGGCGGCGGCGCCACCGGCGTGGAACTGGCGGCCGAGCT
GCACGCCGCAGCGCGCGTGCTGGCCAACTACGGCTTTGACCATATTCATCCCGAAAAGGATTTGCAGATTGTGCTGGTGG
AGGCAGCACCGCGCCTGCTGGCGCAATTGCCGGAACGCCTGAGCGAATCGGCCCTGCGCGAGCTGCGCAAGCTGGCGATT
GAAGTGCACACCAATGAGAAAGTGGTTGAGGTCACCGCGGACGGCCTGAAGATGGCCAGCGGCAAGGTGGTGCCGTCCAG
CATCACCGTGTGGGCGGCCGGCGTGAAGGCGGCTGATTTTTTAAAGACCATTGGCGCGGGGCCCGACGGCGCGGAGCCGC
TGGAGACCAGCAGGCTCAACCAGCTGATCGTCAACGGCAACCTGCAGACCACCCGCGACCCGAGCATTTATGCCTTTGGC
GATTGCGCCGCCTGCCAGCAGCCTGATGGCACCTGGGTGCCGCCGCGCGCACAGGCCGCCTACCAGCAGGCCATGTACCT
GGCCCGGGCGCTGCCGCTGCTGGGCGCGGGCAAGACAGTGAGGCCCTTTGTCTTCAGGGACCAGGGCTCGCTGGTGTCGC
TGGCCGAATATTCGTCGGTGGGCAGCCTGATGGGCAGCCTCTCCCACGGCAGCTTTTTCATCGAGGGCCAGCTGGCCAAA
CTGATGTACTGGGCGCTGCACAAACAGCACCAGCTGGCACTGGGCGGCCTGAAGAAAACCCTGCTGATCACACTGTCTGA
AATGATTGACCGGACGCACCGGCCACGCATAAAGTTGCATTGA

Upstream 100 bases:

>100_bases
GACCGTGGACTGAGGGTGAACCGAGCATCGCCTGGGACCAGCCCAGTTAACATGGCGCCACAACAAAGTTAATGGATTCT
TGATCCGCTGAGGGAATTTT

Downstream 100 bases:

>100_bases
TAATCAGGACTCAATCTAACCGGAGAATGCCATGGCAAAAGGTCAACAAAACAGCAACAAGATGGTCAAGAAGCCCAAGA
AGGACTCGTCACCACCCAAA

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MQRIVIVGGGAGGLALATQLGKRLGKKGLAEITLVDAARTHVWKPLLHQLAAGSFDTHAEEIEYLAQARWNHFKFRLGSL
VGIDRHSKTLQLAASHDAAGREITPAQQLGYDTLVIAVGSQTNDFGTLGAAEHTIKLDSPQAAQHFNDRLINAFIRAQTV
PRTAGSGRLTVAIVGGGATGVELAAELHAAARVLANYGFDHIHPEKDLQIVLVEAAPRLLAQLPERLSESALRELRKLAI
EVHTNEKVVEVTADGLKMASGKVVPSSITVWAAGVKAADFLKTIGAGPDGAEPLETSRLNQLIVNGNLQTTRDPSIYAFG
DCAACQQPDGTWVPPRAQAAYQQAMYLARALPLLGAGKTVRPFVFRDQGSLVSLAEYSSVGSLMGSLSHGSFFIEGQLAK
LMYWALHKQHQLALGGLKKTLLITLSEMIDRTHRPRIKLH

Sequences:

>Translated_440_residues
MQRIVIVGGGAGGLALATQLGKRLGKKGLAEITLVDAARTHVWKPLLHQLAAGSFDTHAEEIEYLAQARWNHFKFRLGSL
VGIDRHSKTLQLAASHDAAGREITPAQQLGYDTLVIAVGSQTNDFGTLGAAEHTIKLDSPQAAQHFNDRLINAFIRAQTV
PRTAGSGRLTVAIVGGGATGVELAAELHAAARVLANYGFDHIHPEKDLQIVLVEAAPRLLAQLPERLSESALRELRKLAI
EVHTNEKVVEVTADGLKMASGKVVPSSITVWAAGVKAADFLKTIGAGPDGAEPLETSRLNQLIVNGNLQTTRDPSIYAFG
DCAACQQPDGTWVPPRAQAAYQQAMYLARALPLLGAGKTVRPFVFRDQGSLVSLAEYSSVGSLMGSLSHGSFFIEGQLAK
LMYWALHKQHQLALGGLKKTLLITLSEMIDRTHRPRIKLH
>Mature_440_residues
MQRIVIVGGGAGGLALATQLGKRLGKKGLAEITLVDAARTHVWKPLLHQLAAGSFDTHAEEIEYLAQARWNHFKFRLGSL
VGIDRHSKTLQLAASHDAAGREITPAQQLGYDTLVIAVGSQTNDFGTLGAAEHTIKLDSPQAAQHFNDRLINAFIRAQTV
PRTAGSGRLTVAIVGGGATGVELAAELHAAARVLANYGFDHIHPEKDLQIVLVEAAPRLLAQLPERLSESALRELRKLAI
EVHTNEKVVEVTADGLKMASGKVVPSSITVWAAGVKAADFLKTIGAGPDGAEPLETSRLNQLIVNGNLQTTRDPSIYAFG
DCAACQQPDGTWVPPRAQAAYQQAMYLARALPLLGAGKTVRPFVFRDQGSLVSLAEYSSVGSLMGSLSHGSFFIEGQLAK
LMYWALHKQHQLALGGLKKTLLITLSEMIDRTHRPRIKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=440, Percent_Identity=47.9545454545455, Blast_Score=402, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6323794, Length=362, Percent_Identity=27.0718232044199, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320118, Length=363, Percent_Identity=27.8236914600551, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323515, Length=457, Percent_Identity=24.2888402625821, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47264; Mature: 47264

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRIVIVGGGAGGLALATQLGKRLGKKGLAEITLVDAARTHVWKPLLHQLAAGSFDTHAE
CCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHH
EIEYLAQARWNHFKFRLGSLVGIDRHSKTLQLAASHDAAGREITPAQQLGYDTLVIAVGS
HHHHHHHHHCCHHEEECCCEEECCCCCCEEEEEECCCCCCCCCCCHHHCCCEEEEEEECC
QTNDFGTLGAAEHTIKLDSPQAAQHFNDRLINAFIRAQTVPRTAGSGRLTVAIVGGGATG
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCH
VELAAELHAAARVLANYGFDHIHPEKDLQIVLVEAAPRLLAQLPERLSESALRELRKLAI
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHEE
EVHTNEKVVEVTADGLKMASGKVVPSSITVWAAGVKAADFLKTIGAGPDGAEPLETSRLN
EEECCCEEEEEECCCEEECCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCHHHHHC
QLIVNGNLQTTRDPSIYAFGDCAACQQPDGTWVPPRAQAAYQQAMYLARALPLLGAGKTV
EEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
RPFVFRDQGSLVSLAEYSSVGSLMGSLSHGSFFIEGQLAKLMYWALHKQHQLALGGLKKT
CCEEEECCCCEEEHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LLITLSEMIDRTHRPRIKLH
HHHHHHHHHHHCCCCCEECC
>Mature Secondary Structure
MQRIVIVGGGAGGLALATQLGKRLGKKGLAEITLVDAARTHVWKPLLHQLAAGSFDTHAE
CCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHH
EIEYLAQARWNHFKFRLGSLVGIDRHSKTLQLAASHDAAGREITPAQQLGYDTLVIAVGS
HHHHHHHHHCCHHEEECCCEEECCCCCCEEEEEECCCCCCCCCCCHHHCCCEEEEEEECC
QTNDFGTLGAAEHTIKLDSPQAAQHFNDRLINAFIRAQTVPRTAGSGRLTVAIVGGGATG
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCH
VELAAELHAAARVLANYGFDHIHPEKDLQIVLVEAAPRLLAQLPERLSESALRELRKLAI
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHEE
EVHTNEKVVEVTADGLKMASGKVVPSSITVWAAGVKAADFLKTIGAGPDGAEPLETSRLN
EEECCCEEEEEECCCEEECCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCHHHHHC
QLIVNGNLQTTRDPSIYAFGDCAACQQPDGTWVPPRAQAAYQQAMYLARALPLLGAGKTV
EEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
RPFVFRDQGSLVSLAEYSSVGSLMGSLSHGSFFIEGQLAKLMYWALHKQHQLALGGLKKT
CCEEEECCCCEEEHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LLITLSEMIDRTHRPRIKLH
HHHHHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]