Click here to switch to the map view.

The map label for this gene is mutS [H]

Identifier: 91789173

GI number: 91789173

Start: 3512480

End: 3512956

Strand: Direct

Name: mutS [H]

Synonym: Bpro_3316

Alternate gene names: 91789173

Gene position: 3512480-3512956 (Clockwise)

Preceding gene: 91789172

Following gene: 91789179

Centisome position: 67.54

GC content: 61.43

Gene sequence:

>477_bases
TTGACGAAAAGCGAAAAAACAACCAGCCTACAAAGGGAGAATAGGATAACGTCGCCTCACACGCCCATGATGCAGCAGTA
CCTTGGCATCAAGGCCGGTTACCCCGACACGCTGGTTTTCTACCGCATGGGTGACTTTTACGAAGTCTTTTTCGCCGATG
CCGAAAAAGCCGCGCGCCTGCTCGACATCACGCTGACGCGGCGCGGCCAGTCGGGCGGCGAGCCGGTGGTGATGGCCGGC
GTGCCCTTTCATTCGCTGGAAGGCTACCTGGCCAAACTGATCAAGCTCGGCGAGTCCGTCGCCATCTGCAAGCAGGTCGG
TGACGTCGCGACATCCAAGGGCCCGGTCGAGCGCAAGGTGGTGCGCGTGGTAACGCCTGGCACGCTGACCGATACCGAGC
TGCTGAACGACAAGGCCGAATCGATTTTCTGGCCGTGCACCAAGGCGCGCGCGACACCTGCGGGCTGGCCTGGCTGA

Upstream 100 bases:

>100_bases
TTCAGTTTTGGCGCTAAATTGGTGGAATTTTGCCAATCAAATTTGCTGAATTGCAACGCGTAAAAGGAAGATAGAGATTG
ATAGACAAGGTCGTGAAAAG

Downstream 100 bases:

>100_bases
GCGCTACGCAGGGTGAAATTCACCTGACCCATTGCACCAATGACGGTGACATCGCCGTGACCTGGGCTCTGGATGGGCAC
GGCATCCTCATGCGTGCCGA

Product: DNA mismatch repair protein MutS-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MTKSEKTTSLQRENRITSPHTPMMQQYLGIKAGYPDTLVFYRMGDFYEVFFADAEKAARLLDITLTRRGQSGGEPVVMAG
VPFHSLEGYLAKLIKLGESVAICKQVGDVATSKGPVERKVVRVVTPGTLTDTELLNDKAESIFWPCTKARATPAGWPG

Sequences:

>Translated_158_residues
MTKSEKTTSLQRENRITSPHTPMMQQYLGIKAGYPDTLVFYRMGDFYEVFFADAEKAARLLDITLTRRGQSGGEPVVMAG
VPFHSLEGYLAKLIKLGESVAICKQVGDVATSKGPVERKVVRVVTPGTLTDTELLNDKAESIFWPCTKARATPAGWPG
>Mature_157_residues
TKSEKTTSLQRENRITSPHTPMMQQYLGIKAGYPDTLVFYRMGDFYEVFFADAEKAARLLDITLTRRGQSGGEPVVMAGV
PFHSLEGYLAKLIKLGESVAICKQVGDVATSKGPVERKVVRVVTPGTLTDTELLNDKAESIFWPCTKARATPAGWPG

Specific function: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity [H]

COG id: COG0249

COG function: function code L; Mismatch repair ATPase (MutS family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA mismatch repair mutS family [H]

Homologues:

Organism=Escherichia coli, GI1789089, Length=132, Percent_Identity=62.1212121212121, Blast_Score=188, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6321912, Length=138, Percent_Identity=35.5072463768116, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320302, Length=142, Percent_Identity=30.9859154929577, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005748
- InterPro:   IPR007695
- InterPro:   IPR000432
- InterPro:   IPR007861
- InterPro:   IPR007860
- InterPro:   IPR007696
- InterPro:   IPR016151 [H]

Pfam domain/function: PF01624 MutS_I; PF05188 MutS_II; PF05192 MutS_III; PF05190 MutS_IV; PF00488 MutS_V [H]

EC number: NA

Molecular weight: Translated: 17353; Mature: 17222

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSEKTTSLQRENRITSPHTPMMQQYLGIKAGYPDTLVFYRMGDFYEVFFADAEKAARL
CCCCCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHCHHHHHHH
LDITLTRRGQSGGEPVVMAGVPFHSLEGYLAKLIKLGESVAICKQVGDVATSKGPVERKV
HHHEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEE
VRVVTPGTLTDTELLNDKAESIFWPCTKARATPAGWPG
EEEECCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKSEKTTSLQRENRITSPHTPMMQQYLGIKAGYPDTLVFYRMGDFYEVFFADAEKAARL
CCCCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHCHHHHHHH
LDITLTRRGQSGGEPVVMAGVPFHSLEGYLAKLIKLGESVAICKQVGDVATSKGPVERKV
HHHEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEE
VRVVTPGTLTDTELLNDKAESIFWPCTKARATPAGWPG
EEEECCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA