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The map label for this gene is nuoL [H]

Identifier: 91789105

GI number: 91789105

Start: 3435197

End: 3437233

Strand: Reverse

Name: nuoL [H]

Synonym: Bpro_3245

Alternate gene names: 91789105

Gene position: 3437233-3435197 (Counterclockwise)

Preceding gene: 91789106

Following gene: 91789104

Centisome position: 66.1

GC content: 57.88

Gene sequence:

>2037_bases
ATGAGCGCAACCCTTTCTGCATCAACATTGCTGGCCGTTCCGCTGGCACCTCTGGCTGGCGCCATGCTGGCTGGTATTCT
GGGTACTTCCTTTGGTGGCAACTGGATAGGCCGCCGGCTGTCCCATAGCCTCACCATCCTCGGCGTGCTGGTAGCCTTCA
TCATTTCTGCCATGACGCTCAAGAGCGTGGTTCTCGAGGGTGCGCGCTTCAATGAAACGCTCTACACCTGGATGGTGGTG
GGCGGCCTGAAAATGGAAGTCGGCTTTCTTGTCGATGGCCTGACGGCCATGATGATGTGCGTGGTGACTTTTGTCTCGCT
GATGGTGCATATCTACACGATTGGCTATATGGAAGAAGACGACGGTTACAACCGCTTCTTTGCCTATATTTCGCTCTTCA
CTTTCTCCATGCTGATGCTGGTGATGAGCAACAACATGCTGCAGCTGTTCTTTGGCTGGGAAGCGGTGGGCCTGGTGTCC
TACCTGCTGATCGGCTTCTGGTTCAACAAGCCGAGCGCCATTTTTGCCAACATGAAGGCCTTCATCGTCAACCGTGTGGG
GGACTTCGGCTTCATCCTGGGTATTGGCCTCATTGCAGCCTACGCCGGTACGCTCAACTATGCCGAAGCGTTTGCCAAGG
CGGATGAGCTGTCCAAACTGGCGTTCCCGGGGACCGGCTGGATGCTGATTACCGTGATCTGCATCTGCCTCTTTATTGGC
GCCATGGGCAAGTCGGCCCAGTTCCCGCTGCATGTGTGGTTGCCCGACTCCATGGAAGGCCCGACCCCGATTTCCGCGTT
GATTCACGCCGCGACCATGGTGACTGCCGGCATCTTCATGGTGGCACGCATGTCACCGCTGTTTGAACTCAGCGATACCG
CCCTCAGCTTCATCATGGTGATCGGGGCGATCACGGCCCTGTTCATGGGCTTCCTCGGCATCATCCAGAACGACATCAAG
CGCGTGGTGGCTTATTCCACCTTGTCGCAGCTCGGCTACATGACGGTGGCCCTGGGTGCTTCCGCCTACTCCGTGGCCGT
GTTCCACCTGATGACGCACGCGTTCTTCAAGGCACTACTGTTCCTGGCTGCCGGCTCGGTGATCATCGGCATGCATCACA
ACCAGGATATCCGCTGGATGGGGGGCGTGCGCAAGTACATGCCCATCACCTGGATCACCTCGCTGCTCGGATCGCTTGCA
CTGATCGGTACGCCGCTGTTCGCAGGTTTTTACTCCAAGGACAGCATCATTGAAGCGGTGCATGAGAGCCACCTGGCGGG
TGCCGGTTTCGCGCATTTCGCGGTGCTGGCCGGTGTGTTTGTCACGGCGTTCTATTCCTTCCGCATGTACTTCCTGGTAT
TCCACGGCAAGGAGCGTTTTGACCAGAACCCCGATGGACACCACCATGACGCCAGCGAGGAACCGGATCCGCACCACCAT
CGCGAAGAACATCAGGCTCCGCACGAGTCACCGTGGGTGGTCACCGTCCCACTGATCCTGCTGGCCATTCCGTCTGTGGT
CATCGGCTTCATGACGATTCAGCCCATGCTGTTTGGTGAATTCTTTAAGGATGCGATTTTCTTCAATGCCGAGAAACATC
CCGCGATGGCCGAGTTGGCCAAGGCCTTCCACGGCCCGGCGCAAATGGCCTTGCACGGCCTGATGACAGCACCGTTCTGG
CTGGCGCTGGCGGGCGTGGTGCTGGCGTATTACATGTACCTGGTCAACCCCGCGCTGCCTGCGCGCATCAAGCGCGCGGT
GCAACCCCTCTACACGTTGCTCGAGAACAAATACTACTTCGACTGGTTCAACGAGAACGTGCTGGCCCGCGCAACGCGTG
CGATGGGTACCGGTCTGTGGAAGGGCGGCGACGAGGCACTGATCGATGGTGCGCTGGTCAACGGCTCCTGGAAACTGGTG
GGCTGGGTGTCCAGCGTGGTGCGAAGGCTGCAGTCGGGTTACATCTACCACTACGCTTTTGGCATGATCATCGGCGTCTT
TTTATTGATGACGTATTTCGTTTGGCTGAACCAATAA

Upstream 100 bases:

>100_bases
TGTACCCCCACGCTTTTCACTTCGAGCCTTCGGCGCGCAGCCCTTTGAACGACGTTTGGGGCGCACTTCTAATTAAGGCA
GCCCTACGGGCGGTTAAACA

Downstream 100 bases:

>100_bases
CACGCGAATAATAAGAAGGAAAAACGAGAATGGGTTTGTTGAGCCTTGCCATCTGGACGCCGATTATTTTCGGTGCCGTG
TTGTTGGCGCTGGGTCGTGA

Product: proton-translocating NADH-quinone oxidoreductase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 678; Mature: 677

Protein sequence:

>678_residues
MSATLSASTLLAVPLAPLAGAMLAGILGTSFGGNWIGRRLSHSLTILGVLVAFIISAMTLKSVVLEGARFNETLYTWMVV
GGLKMEVGFLVDGLTAMMMCVVTFVSLMVHIYTIGYMEEDDGYNRFFAYISLFTFSMLMLVMSNNMLQLFFGWEAVGLVS
YLLIGFWFNKPSAIFANMKAFIVNRVGDFGFILGIGLIAAYAGTLNYAEAFAKADELSKLAFPGTGWMLITVICICLFIG
AMGKSAQFPLHVWLPDSMEGPTPISALIHAATMVTAGIFMVARMSPLFELSDTALSFIMVIGAITALFMGFLGIIQNDIK
RVVAYSTLSQLGYMTVALGASAYSVAVFHLMTHAFFKALLFLAAGSVIIGMHHNQDIRWMGGVRKYMPITWITSLLGSLA
LIGTPLFAGFYSKDSIIEAVHESHLAGAGFAHFAVLAGVFVTAFYSFRMYFLVFHGKERFDQNPDGHHHDASEEPDPHHH
REEHQAPHESPWVVTVPLILLAIPSVVIGFMTIQPMLFGEFFKDAIFFNAEKHPAMAELAKAFHGPAQMALHGLMTAPFW
LALAGVVLAYYMYLVNPALPARIKRAVQPLYTLLENKYYFDWFNENVLARATRAMGTGLWKGGDEALIDGALVNGSWKLV
GWVSSVVRRLQSGYIYHYAFGMIIGVFLLMTYFVWLNQ

Sequences:

>Translated_678_residues
MSATLSASTLLAVPLAPLAGAMLAGILGTSFGGNWIGRRLSHSLTILGVLVAFIISAMTLKSVVLEGARFNETLYTWMVV
GGLKMEVGFLVDGLTAMMMCVVTFVSLMVHIYTIGYMEEDDGYNRFFAYISLFTFSMLMLVMSNNMLQLFFGWEAVGLVS
YLLIGFWFNKPSAIFANMKAFIVNRVGDFGFILGIGLIAAYAGTLNYAEAFAKADELSKLAFPGTGWMLITVICICLFIG
AMGKSAQFPLHVWLPDSMEGPTPISALIHAATMVTAGIFMVARMSPLFELSDTALSFIMVIGAITALFMGFLGIIQNDIK
RVVAYSTLSQLGYMTVALGASAYSVAVFHLMTHAFFKALLFLAAGSVIIGMHHNQDIRWMGGVRKYMPITWITSLLGSLA
LIGTPLFAGFYSKDSIIEAVHESHLAGAGFAHFAVLAGVFVTAFYSFRMYFLVFHGKERFDQNPDGHHHDASEEPDPHHH
REEHQAPHESPWVVTVPLILLAIPSVVIGFMTIQPMLFGEFFKDAIFFNAEKHPAMAELAKAFHGPAQMALHGLMTAPFW
LALAGVVLAYYMYLVNPALPARIKRAVQPLYTLLENKYYFDWFNENVLARATRAMGTGLWKGGDEALIDGALVNGSWKLV
GWVSSVVRRLQSGYIYHYAFGMIIGVFLLMTYFVWLNQ
>Mature_677_residues
SATLSASTLLAVPLAPLAGAMLAGILGTSFGGNWIGRRLSHSLTILGVLVAFIISAMTLKSVVLEGARFNETLYTWMVVG
GLKMEVGFLVDGLTAMMMCVVTFVSLMVHIYTIGYMEEDDGYNRFFAYISLFTFSMLMLVMSNNMLQLFFGWEAVGLVSY
LLIGFWFNKPSAIFANMKAFIVNRVGDFGFILGIGLIAAYAGTLNYAEAFAKADELSKLAFPGTGWMLITVICICLFIGA
MGKSAQFPLHVWLPDSMEGPTPISALIHAATMVTAGIFMVARMSPLFELSDTALSFIMVIGAITALFMGFLGIIQNDIKR
VVAYSTLSQLGYMTVALGASAYSVAVFHLMTHAFFKALLFLAAGSVIIGMHHNQDIRWMGGVRKYMPITWITSLLGSLAL
IGTPLFAGFYSKDSIIEAVHESHLAGAGFAHFAVLAGVFVTAFYSFRMYFLVFHGKERFDQNPDGHHHDASEEPDPHHHR
EEHQAPHESPWVVTVPLILLAIPSVVIGFMTIQPMLFGEFFKDAIFFNAEKHPAMAELAKAFHGPAQMALHGLMTAPFWL
ALAGVVLAYYMYLVNPALPARIKRAVQPLYTLLENKYYFDWFNENVLARATRAMGTGLWKGGDEALIDGALVNGSWKLVG
WVSSVVRRLQSGYIYHYAFGMIIGVFLLMTYFVWLNQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=386, Percent_Identity=40.9326424870466, Blast_Score=281, Evalue=1e-75,
Organism=Escherichia coli, GI1788614, Length=545, Percent_Identity=40.5504587155963, Blast_Score=360, Evalue=1e-100,
Organism=Escherichia coli, GI1788829, Length=339, Percent_Identity=30.3834808259587, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788831, Length=403, Percent_Identity=27.7915632754342, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI1788827, Length=424, Percent_Identity=29.4811320754717, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1788613, Length=333, Percent_Identity=26.4264264264264, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI145693160, Length=401, Percent_Identity=24.4389027431421, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI2367154, Length=189, Percent_Identity=29.6296296296296, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR002128
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF01010 Oxidored_q1_C; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 74686; Mature: 74555

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SATLSASTLLAVPLAPLAGAMLAGILGTSFGGNWIGRRLSHSLTILGVLVAFIISAMTL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]