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The map label for this gene is nuoN [H]

Identifier: 91789103

GI number: 91789103

Start: 3432176

End: 3433678

Strand: Reverse

Name: nuoN [H]

Synonym: Bpro_3243

Alternate gene names: 91789103

Gene position: 3433678-3432176 (Counterclockwise)

Preceding gene: 91789104

Following gene: 91789102

Centisome position: 66.03

GC content: 60.28

Gene sequence:

>1503_bases
ATGATTGACAAACTCTCCTGGATCACGGTTTATCCTGAAATCGTCCTCGTGATCATGGCCTGCGTGATCGCGCTGCTGGA
TCTCGGGGTGAAAACCCCGCGCCGCACCGGCACCTATGTGCTGACCTTGTTGACGCTGGCCGTGGTTGCTGCCATGGAGG
CCTTCTACGCGCTGGGCGGCCAGACTTTCTACGGCTTTGGCGGCATGGTGGTCAGCGACCCGATGGGGGGTTGGCTCAAG
TGTTTTTCCAGTATCAGCCTGATGGTGACGCTGGTCTATGGCCGGCCTTATGCGGCCGACCGCGAGATGCTGCGCGGCGG
TGAACTGTTCACGCTGAGCCTGTTTGCCTTGCTGGGCATGTTCGTGATGATCTCGGGCCACAACTTCCTCGTGATCTACA
TGGGTCTGGAGCTGATGACGCTGTCCAGCTACGCCCTGGTGGCCCTGCGCCGCGACAATGCCACCGCCACGGAAGCCGCG
ATGAAGTACTTTGTGCTGGGTGCGCTGGCTTCCGGCTTCCTGCTCTACGGCCTGTCGATGCTGTATGGTGCGACCGGCTC
GCTGGACCTCAATGAAGTGTTCAATGCGATTGCCAGCCGCCAGGTCAAGCATCAGGTGCTGGTCTTTGGCCTGGTGTTCA
TTGTGGCCGGCCTGGCGTTCAAACTGGGCGCCGTGCCTTTCCACATGTGGTTGCCCGACGTCTACCACGGCGCGCCGACG
GCCATCACCCTGCTGATTGGCGGTGCACCGCAGCTGGCGGCTTTTGCGATCTGTATCCGTCTGCTGGTGGAGGGCCTGCT
GCCCCTGGCCATTGACTGGCAGCAGATGCTTGCGCTGATGGCCATCGGCTCGCTGATCATTGGCAATCTGGCCGCCGTCG
CGCAGTCCAACCTCAAGCGCATGCTGGCGTTTTCAACGATTTCGCAAATGGGTTTCCTGCTGCTTGGCTTGCTGGCCGGG
GTGGTCAACGGCAACCAGATGAACACGGAATCAGCCTACAGTGCTGCGATGTTCTATGCGGTGACCTATGTACTCACCAC
GCTGGGTGCCTTCGGCATCATCTTGCTGCTGGCCCGTGTCGGGCACGAGTCTGAAGAAATCACCGACCTGGCCGGTCTCA
ACCAGCGCAGCCCGCTGTATGCCGGGGTCATGGCCATTGCGATGTTCTCGCTGGCTGGCCTGCCTCCGCTCGTGGGCTTT
TATGCCAAGCTGGCCGTGTTGCAGGCGCTGATTTCATCGCAGCAGACCAGCTATATTCTGCTCGCCATCTTTGCCGTGAT
GATGTCGCTGATTGGCGCGTTTTACTACCTGCGCGTGGTCAAGGTGATGTACTTTGATGCGCCCGAGGCCCACAATGCGC
AACCGATCTCGGCACCCACAGATGCCAAGGCGGTGCTGGCTATCAACGGCGCGCTCATTCTGCTGCTGGGCATGCTTCCC
GGTGGCCTGATGACTCTGTGTGCGCAGTCCATCAACAGCATCGTCAAGTCGCTCGGAAACTAG

Upstream 100 bases:

>100_bases
GGCATTTATCCCAAGCCGTTTACCGATGTGATGAACCCGTCGGTGGCCGACCTGCTCAAGCATGTCGCGGCATCGAAACT
GAACTAGGCAAAGAATTCAG

Downstream 100 bases:

>100_bases
ACCTCCCCCATGAGTCAGACTGCTTCAGTCTGGGTGGTTGTATTGCTGGCGTTGCTGTTGGCCAATCTGCCCTTCGTCAG
CAACCGCCTTTTCGGGGTGA

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MIDKLSWITVYPEIVLVIMACVIALLDLGVKTPRRTGTYVLTLLTLAVVAAMEAFYALGGQTFYGFGGMVVSDPMGGWLK
CFSSISLMVTLVYGRPYAADREMLRGGELFTLSLFALLGMFVMISGHNFLVIYMGLELMTLSSYALVALRRDNATATEAA
MKYFVLGALASGFLLYGLSMLYGATGSLDLNEVFNAIASRQVKHQVLVFGLVFIVAGLAFKLGAVPFHMWLPDVYHGAPT
AITLLIGGAPQLAAFAICIRLLVEGLLPLAIDWQQMLALMAIGSLIIGNLAAVAQSNLKRMLAFSTISQMGFLLLGLLAG
VVNGNQMNTESAYSAAMFYAVTYVLTTLGAFGIILLLARVGHESEEITDLAGLNQRSPLYAGVMAIAMFSLAGLPPLVGF
YAKLAVLQALISSQQTSYILLAIFAVMMSLIGAFYYLRVVKVMYFDAPEAHNAQPISAPTDAKAVLAINGALILLLGMLP
GGLMTLCAQSINSIVKSLGN

Sequences:

>Translated_500_residues
MIDKLSWITVYPEIVLVIMACVIALLDLGVKTPRRTGTYVLTLLTLAVVAAMEAFYALGGQTFYGFGGMVVSDPMGGWLK
CFSSISLMVTLVYGRPYAADREMLRGGELFTLSLFALLGMFVMISGHNFLVIYMGLELMTLSSYALVALRRDNATATEAA
MKYFVLGALASGFLLYGLSMLYGATGSLDLNEVFNAIASRQVKHQVLVFGLVFIVAGLAFKLGAVPFHMWLPDVYHGAPT
AITLLIGGAPQLAAFAICIRLLVEGLLPLAIDWQQMLALMAIGSLIIGNLAAVAQSNLKRMLAFSTISQMGFLLLGLLAG
VVNGNQMNTESAYSAAMFYAVTYVLTTLGAFGIILLLARVGHESEEITDLAGLNQRSPLYAGVMAIAMFSLAGLPPLVGF
YAKLAVLQALISSQQTSYILLAIFAVMMSLIGAFYYLRVVKVMYFDAPEAHNAQPISAPTDAKAVLAINGALILLLGMLP
GGLMTLCAQSINSIVKSLGN
>Mature_500_residues
MIDKLSWITVYPEIVLVIMACVIALLDLGVKTPRRTGTYVLTLLTLAVVAAMEAFYALGGQTFYGFGGMVVSDPMGGWLK
CFSSISLMVTLVYGRPYAADREMLRGGELFTLSLFALLGMFVMISGHNFLVIYMGLELMTLSSYALVALRRDNATATEAA
MKYFVLGALASGFLLYGLSMLYGATGSLDLNEVFNAIASRQVKHQVLVFGLVFIVAGLAFKLGAVPFHMWLPDVYHGAPT
AITLLIGGAPQLAAFAICIRLLVEGLLPLAIDWQQMLALMAIGSLIIGNLAAVAQSNLKRMLAFSTISQMGFLLLGLLAG
VVNGNQMNTESAYSAAMFYAVTYVLTTLGAFGIILLLARVGHESEEITDLAGLNQRSPLYAGVMAIAMFSLAGLPPLVGF
YAKLAVLQALISSQQTSYILLAIFAVMMSLIGAFYYLRVVKVMYFDAPEAHNAQPISAPTDAKAVLAINGALILLLGMLP
GGLMTLCAQSINSIVKSLGN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=317, Percent_Identity=24.9211356466877, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI145693160, Length=388, Percent_Identity=33.2474226804124, Blast_Score=194, Evalue=9e-51,
Organism=Escherichia coli, GI1788827, Length=392, Percent_Identity=26.7857142857143, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1788614, Length=420, Percent_Identity=24.7619047619048, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788831, Length=325, Percent_Identity=23.0769230769231, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788613, Length=273, Percent_Identity=27.1062271062271, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI2367154, Length=351, Percent_Identity=24.2165242165242, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 53410; Mature: 53410

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKLSWITVYPEIVLVIMACVIALLDLGVKTPRRTGTYVLTLLTLAVVAAMEAFYALGG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
QTFYGFGGMVVSDPMGGWLKCFSSISLMVTLVYGRPYAADREMLRGGELFTLSLFALLGM
CEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHH
FVMISGHNFLVIYMGLELMTLSSYALVALRRDNATATEAAMKYFVLGALASGFLLYGLSM
HHHHCCCCEEEEEECHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGATGSLDLNEVFNAIASRQVKHQVLVFGLVFIVAGLAFKLGAVPFHMWLPDVYHGAPT
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHCCCCC
AITLLIGGAPQLAAFAICIRLLVEGLLPLAIDWQQMLALMAIGSLIIGNLAAVAQSNLKR
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLAFSTISQMGFLLLGLLAGVVNGNQMNTESAYSAAMFYAVTYVLTTLGAFGIILLLARV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHESEEITDLAGLNQRSPLYAGVMAIAMFSLAGLPPLVGFYAKLAVLQALISSQQTSYIL
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
LAIFAVMMSLIGAFYYLRVVKVMYFDAPEAHNAQPISAPTDAKAVLAINGALILLLGMLP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHCC
GGLMTLCAQSINSIVKSLGN
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDKLSWITVYPEIVLVIMACVIALLDLGVKTPRRTGTYVLTLLTLAVVAAMEAFYALGG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
QTFYGFGGMVVSDPMGGWLKCFSSISLMVTLVYGRPYAADREMLRGGELFTLSLFALLGM
CEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHH
FVMISGHNFLVIYMGLELMTLSSYALVALRRDNATATEAAMKYFVLGALASGFLLYGLSM
HHHHCCCCEEEEEECHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGATGSLDLNEVFNAIASRQVKHQVLVFGLVFIVAGLAFKLGAVPFHMWLPDVYHGAPT
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHCCCCC
AITLLIGGAPQLAAFAICIRLLVEGLLPLAIDWQQMLALMAIGSLIIGNLAAVAQSNLKR
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLAFSTISQMGFLLLGLLAGVVNGNQMNTESAYSAAMFYAVTYVLTTLGAFGIILLLARV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHESEEITDLAGLNQRSPLYAGVMAIAMFSLAGLPPLVGFYAKLAVLQALISSQQTSYIL
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
LAIFAVMMSLIGAFYYLRVVKVMYFDAPEAHNAQPISAPTDAKAVLAINGALILLLGMLP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHCC
GGLMTLCAQSINSIVKSLGN
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA