Click here to switch to the map view.

The map label for this gene is nudF [H]

Identifier: 91789101

GI number: 91789101

Start: 3431232

End: 3431834

Strand: Reverse

Name: nudF [H]

Synonym: Bpro_3241

Alternate gene names: 91789101

Gene position: 3431834-3431232 (Counterclockwise)

Preceding gene: 91789102

Following gene: 91789100

Centisome position: 65.99

GC content: 63.02

Gene sequence:

>603_bases
ATGAACTCCAGCGAATCCAGCCATCTGATCGAGACACTGGTCAGCTCCGAAGACATCCTCAAAGGAAACTTTCTTCACGT
TCGCCGCGACACCGTGAGACTGCCCGACGGCACCCCCACGGCGCGCGAGTATGTCATTCATCCGGGCGCCGTGATGATCG
TGGCGCAACTCGACGATGGCAGGCTGGTGCTGGAGCGGCAGTTCCGGTATCCCATGGGTGCCGTGATGATCGAGTTTCCG
GCCGGCAAGCTGGATGCCGGCGAGGCGTCGCTGGCCTGCGCGCAGCGCGAGCTGCTGGAAGAAACCGGCTATACCGCGCG
GCAGTGGGCAAGAGCCGGCGTGCTGCACCCGGTGATTTCCTACTCCACCGAGTTCATTGATATCTGGTTTGCGCGCGACC
TCACGTTGGGAGCCCGCCAGCTGGACAGCGGCGAATTCCTCGAAGTTTTCACCGCCACGCCGGCCGAGCTGTTGGCCTGG
TGCGGCAATGGGCAGGTCACCGATGCCAAGACCCTCACCGGAGCCCTGTGGCTGCAAAACGTGCTGTCGGGGGTATGGGC
ATTGGACTGGCAAACTACCGCGCCGGAGCGGGACTTGCGATAA

Upstream 100 bases:

>100_bases
CGGGCACGCTCTTCATCACCTTTGCATTCCCCGGTTTCACCTGGCGTTACCTGTTCAAGCATCGCTCATGAGCCTGCCTG
GTGCGGGCAAGGAAAATAGC

Downstream 100 bases:

>100_bases
TCTGCCCATGAAAGTCCTGAATCTCCAGTGCGCGCAGCAGCATTCCTTTGAAGGCTGGTTTGCGTCTGAAGACGATTTTC
AGACGCAACTGACGCGTGGA

Product: NUDIX hydrolase

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MNSSESSHLIETLVSSEDILKGNFLHVRRDTVRLPDGTPTAREYVIHPGAVMIVAQLDDGRLVLERQFRYPMGAVMIEFP
AGKLDAGEASLACAQRELLEETGYTARQWARAGVLHPVISYSTEFIDIWFARDLTLGARQLDSGEFLEVFTATPAELLAW
CGNGQVTDAKTLTGALWLQNVLSGVWALDWQTTAPERDLR

Sequences:

>Translated_200_residues
MNSSESSHLIETLVSSEDILKGNFLHVRRDTVRLPDGTPTAREYVIHPGAVMIVAQLDDGRLVLERQFRYPMGAVMIEFP
AGKLDAGEASLACAQRELLEETGYTARQWARAGVLHPVISYSTEFIDIWFARDLTLGARQLDSGEFLEVFTATPAELLAW
CGNGQVTDAKTLTGALWLQNVLSGVWALDWQTTAPERDLR
>Mature_200_residues
MNSSESSHLIETLVSSEDILKGNFLHVRRDTVRLPDGTPTAREYVIHPGAVMIVAQLDDGRLVLERQFRYPMGAVMIEFP
AGKLDAGEASLACAQRELLEETGYTARQWARAGVLHPVISYSTEFIDIWFARDLTLGARQLDSGEFLEVFTATPAELLAW
CGNGQVTDAKTLTGALWLQNVLSGVWALDWQTTAPERDLR

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 22190; Mature: 22190

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSESSHLIETLVSSEDILKGNFLHVRRDTVRLPDGTPTAREYVIHPGAVMIVAQLDDG
CCCCHHHHHHHHHHCCCCHHCCCEEEEEECEEECCCCCCCCCEEEECCCEEEEEEEECCC
RLVLERQFRYPMGAVMIEFPAGKLDAGEASLACAQRELLEETGYTARQWARAGVLHPVIS
EEEEEEHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHH
YSTEFIDIWFARDLTLGARQLDSGEFLEVFTATPAELLAWCGNGQVTDAKTLTGALWLQN
CCCCEEEEEEECCCCCCHHCCCCCCEEEEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHH
VLSGVWALDWQTTAPERDLR
HHHHHEEECCCCCCCCCCCC
>Mature Secondary Structure
MNSSESSHLIETLVSSEDILKGNFLHVRRDTVRLPDGTPTAREYVIHPGAVMIVAQLDDG
CCCCHHHHHHHHHHCCCCHHCCCEEEEEECEEECCCCCCCCCEEEECCCEEEEEEEECCC
RLVLERQFRYPMGAVMIEFPAGKLDAGEASLACAQRELLEETGYTARQWARAGVLHPVIS
EEEEEEHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHH
YSTEFIDIWFARDLTLGARQLDSGEFLEVFTATPAELLAWCGNGQVTDAKTLTGALWLQN
CCCCEEEEEEECCCCCCHHCCCCCCEEEEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHH
VLSGVWALDWQTTAPERDLR
HHHHHEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]