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The map label for this gene is phnW1

Identifier: 91789076

GI number: 91789076

Start: 3403111

End: 3404235

Strand: Reverse

Name: phnW1

Synonym: Bpro_3216

Alternate gene names: 91789076

Gene position: 3404235-3403111 (Counterclockwise)

Preceding gene: 91789077

Following gene: 91789075

Centisome position: 65.46

GC content: 65.07

Gene sequence:

>1125_bases
ATGACAACCGACGCCATTCTTCTGACCCCCGGACCGCTGACCACGTCGAGCCGCACCAAGCAAAGCATGCTGCGTGACTG
GGGCTCCTGGGATACGGATTTCAATGCCATCACCGCGCGCCTGCGCCAGGGCCTGCTGCGCATCGTGCACGGCGAAGGCA
CGCATGAGTGCGTTCCCCTGCAGGGCAGCGGTACTTTTTCAGTCGAGGCGGCCATTGGCACGCTGGTGCCGCCGGGCGAA
AAAGGGGGGCATGTGCTGGTGCCGGTCAACGGCGCCTATTGCCAGCGCATCGCCAAAATCTGCAAGGTGCTGGGCCGCAA
GCTCACCACCTTCGAGTATGCGGAAGATGCGCAAATCCGACCCGAAGACATTGACCGGCTGCTCGCCAAGGACCCCTCCA
TCACCCACGTCGCGCTGGTGCACTGCGAAACCAGCACGGGTATTCTGAACCCGCTGCACGAGATTGCACTGGTCGTGCAG
CGCCACGGCAAGGGCTTGATCGTCGATGCGATGAGCTCGTTCGGCGCGCTGGAGATTGATGCACGCAAGACGCCGTTCGA
CGCCGTGGTCGCCGCGTCGGGCAAGTGCCTGGAAGGCGTTCCCGGTATGGGCTTTGTGCTGGCGCGCCGCGCCGCACTGG
AGCGCTGCGAGGGCAACTGCCATTCGCTGGCGATGGACCTGTACGACCAGTGGGTCTACATGAACAAGACCACGCAGTGG
CGCTTTACCCCGCCGACCCATGTGGTGGCCGCGCTGGACGCCGCGCTCACGCAGTATTTCGAACAAGGCGGGCTGGCCGC
GCGCGGCGGCGCCTATGCCAAGAATTGCCGCGAGCTCATCAGTGGCCTGGCCGGGCTGGGCTTGCGCAGCTTCCTGCCCG
CGGCGATCCAGGCGCCCATCATCGTGACCTTCCATGCGCCCGCCAGCCCGGCCTACGAGTTCAAAGCCTTTTACAACGCG
GTCAGGCAGCGCGGCTATATTCTTTACCCCGGAAAACTGACCGCGGTGGAGACTTTTCGCGTCGGTTGCATGGGCCAGCT
CGGCGCGCGCGGCATGGCGGGCGCCGTGGAAGCGGTTCGGGATGCGCTGCAGGAAATGGGGCTGGAGCTTGCCAACGCCG
AGTGA

Upstream 100 bases:

>100_bases
AGACCCAGGCGTGGCGAAACGTCGCCCGCCAATGAAGCCCGATCCCTTCCGACTTGCCACTTTTCCGTTTTTCCATTTGC
CAAACATCCAAGGAGCTTTC

Downstream 100 bases:

>100_bases
CGAGGCGCAGCATCCCGGAGGTGATTTCAAGTATTTGGCGGAACAGAGCTCCCGCGAAATTTCAATGCGGCCTTACGGTG
GAAACGTCACCGCTTTTTGC

Product: 2-aminoethylphosphonate--pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase 1; AEP transaminase 1; AEPT 1

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MTTDAILLTPGPLTTSSRTKQSMLRDWGSWDTDFNAITARLRQGLLRIVHGEGTHECVPLQGSGTFSVEAAIGTLVPPGE
KGGHVLVPVNGAYCQRIAKICKVLGRKLTTFEYAEDAQIRPEDIDRLLAKDPSITHVALVHCETSTGILNPLHEIALVVQ
RHGKGLIVDAMSSFGALEIDARKTPFDAVVAASGKCLEGVPGMGFVLARRAALERCEGNCHSLAMDLYDQWVYMNKTTQW
RFTPPTHVVAALDAALTQYFEQGGLAARGGAYAKNCRELISGLAGLGLRSFLPAAIQAPIIVTFHAPASPAYEFKAFYNA
VRQRGYILYPGKLTAVETFRVGCMGQLGARGMAGAVEAVRDALQEMGLELANAE

Sequences:

>Translated_374_residues
MTTDAILLTPGPLTTSSRTKQSMLRDWGSWDTDFNAITARLRQGLLRIVHGEGTHECVPLQGSGTFSVEAAIGTLVPPGE
KGGHVLVPVNGAYCQRIAKICKVLGRKLTTFEYAEDAQIRPEDIDRLLAKDPSITHVALVHCETSTGILNPLHEIALVVQ
RHGKGLIVDAMSSFGALEIDARKTPFDAVVAASGKCLEGVPGMGFVLARRAALERCEGNCHSLAMDLYDQWVYMNKTTQW
RFTPPTHVVAALDAALTQYFEQGGLAARGGAYAKNCRELISGLAGLGLRSFLPAAIQAPIIVTFHAPASPAYEFKAFYNA
VRQRGYILYPGKLTAVETFRVGCMGQLGARGMAGAVEAVRDALQEMGLELANAE
>Mature_373_residues
TTDAILLTPGPLTTSSRTKQSMLRDWGSWDTDFNAITARLRQGLLRIVHGEGTHECVPLQGSGTFSVEAAIGTLVPPGEK
GGHVLVPVNGAYCQRIAKICKVLGRKLTTFEYAEDAQIRPEDIDRLLAKDPSITHVALVHCETSTGILNPLHEIALVVQR
HGKGLIVDAMSSFGALEIDARKTPFDAVVAASGKCLEGVPGMGFVLARRAALERCEGNCHSLAMDLYDQWVYMNKTTQWR
FTPPTHVVAALDAALTQYFEQGGLAARGGAYAKNCRELISGLAGLGLRSFLPAAIQAPIIVTFHAPASPAYEFKAFYNAV
RQRGYILYPGKLTAVETFRVGCMGQLGARGMAGAVEAVRDALQEMGLELANAE

Specific function: Involved in phosphonate degradation

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily

Homologues:

Organism=Homo sapiens, GI4557289, Length=373, Percent_Identity=24.6648793565684, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17536281, Length=309, Percent_Identity=24.5954692556634, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHNW1_POLSJ (Q128B2)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_550028.1
- ProteinModelPortal:   Q128B2
- SMR:   Q128B2
- STRING:   Q128B2
- GeneID:   4014101
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_3216
- NMPDR:   fig|296591.1.peg.4746
- eggNOG:   COG0075
- HOGENOM:   HBG423997
- OMA:   HSLAMDL
- ProtClustDB:   PRK13479
- BioCyc:   PSP296591:BPRO_3216-MONOMER
- HAMAP:   MF_01376
- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR03301
- TIGRFAMs:   TIGR02326

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.37

Molecular weight: Translated: 40253; Mature: 40122

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDAILLTPGPLTTSSRTKQSMLRDWGSWDTDFNAITARLRQGLLRIVHGEGTHECVPL
CCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEECCCCCCEEEEE
QGSGTFSVEAAIGTLVPPGEKGGHVLVPVNGAYCQRIAKICKVLGRKLTTFEYAEDAQIR
CCCCCEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
PEDIDRLLAKDPSITHVALVHCETSTGILNPLHEIALVVQRHGKGLIVDAMSSFGALEID
HHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECHHCCCCEEEC
ARKTPFDAVVAASGKCLEGVPGMGFVLARRAALERCEGNCHSLAMDLYDQWVYMNKTTQW
CCCCCHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEECCCCEE
RFTPPTHVVAALDAALTQYFEQGGLAARGGAYAKNCRELISGLAGLGLRSFLPAAIQAPI
EECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCE
IVTFHAPASPAYEFKAFYNAVRQRGYILYPGKLTAVETFRVGCMGQLGARGMAGAVEAVR
EEEEECCCCCHHHHHHHHHHHHHCCEEEECCCEEEEHHHHHCCCHHCCCCCHHHHHHHHH
DALQEMGLELANAE
HHHHHCCCHHCCCC
>Mature Secondary Structure 
TTDAILLTPGPLTTSSRTKQSMLRDWGSWDTDFNAITARLRQGLLRIVHGEGTHECVPL
CCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEECCCCCCEEEEE
QGSGTFSVEAAIGTLVPPGEKGGHVLVPVNGAYCQRIAKICKVLGRKLTTFEYAEDAQIR
CCCCCEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
PEDIDRLLAKDPSITHVALVHCETSTGILNPLHEIALVVQRHGKGLIVDAMSSFGALEID
HHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECHHCCCCEEEC
ARKTPFDAVVAASGKCLEGVPGMGFVLARRAALERCEGNCHSLAMDLYDQWVYMNKTTQW
CCCCCHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEECCCCEE
RFTPPTHVVAALDAALTQYFEQGGLAARGGAYAKNCRELISGLAGLGLRSFLPAAIQAPI
EECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCE
IVTFHAPASPAYEFKAFYNAVRQRGYILYPGKLTAVETFRVGCMGQLGARGMAGAVEAVR
EEEEECCCCCHHHHHHHHHHHHHCCEEEECCCEEEEHHHHHCCCHHCCCCCHHHHHHHHH
DALQEMGLELANAE
HHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA