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The map label for this gene is garD [H]

Identifier: 91788964

GI number: 91788964

Start: 3276326

End: 3277972

Strand: Reverse

Name: garD [H]

Synonym: Bpro_3104

Alternate gene names: 91788964

Gene position: 3277972-3276326 (Counterclockwise)

Preceding gene: 91788965

Following gene: 91788963

Centisome position: 63.03

GC content: 63.93

Gene sequence:

>1647_bases
ATGACCTCCCCCAATCCCCCCACACAGGCCGCAGCAAAGGCCGCGCCGCAGGCCGCTCCAGGCACCGCGACGAAGAGGGC
GCCGCTGTACATCACCATGCACGATCATGACAATGTTGCGATCGTGGCCAACGACGGCGGCCTGCCTGCAGGAACGGTAT
TTGACAGCGGTTTGCGGCTGTGCGAGCAGGTGCCGCAGGGTCACAAGGTCGCGCTGGTCGATTTGCCCAAGGGCACCGCG
GTGCTGCGTTACAACGTGCCCATCGGCTATGCGCTCAAGGACATCCCGGCCGGGAGCTGGGTGCATGAGCGGCTGCTGGA
GATGCCTTCGGCGCGCGAGCTCGACAATTTGCCCATCGCCACCGTGCGGCCGCCGGTGCTGCCGCCATTGGAGGGCTATA
CCTTTGAGGGCTACCGCAACCCGGACGGATCGGTCGGCAGCCGCAACATTCTCGCCATCACCACGACCGTGCAGTGTGTG
GCGGGCGTGGTGGAGTTTGCCGTCAAGCGCATCAAGGATGAGTTGCTGCCGCGCTTCCCGAACGTGGATGATGTGGTGGG
CCTGGAGCACACCTATGGGTGCGGCGTGGCCATCGACGCCCCGGACGCGATCATTCCGATCCGCACCCTGCGTAACATCA
CGCTCAACCCGAACTTTGGCGGTGAGGTGATGGTGGTGAGCCTGGGCTGCGAAAAGCTCCAGCCCGAGCGCCTGCTGCCG
CCCGGCACCATTCAGATCGTCGACGAACGCAATGTGGCCGATGTGGGCATTAGCGCCGAGGCCGAGCTCGATGTGGTCTG
CCTGCAATCCGAACACCACGTGGGCTTCATGTCGATGATCGACTCCATCATGGAGACGGCCTTGCTGCACCTGGAGCGGC
TTGATGCCCGCCGGCGCGAAACCGTCCCCGCCAGTGAACTGGTGGTGGGTGTGCAGTGTGGCGGCAGCGATGCTTTTTCC
GGCGTGACGGCCAATCCGGCGGTGGGTTTTGCCACCGATTTGCTGGTGCGCGCCGGTGCCACGGTGATGTTCTCCGAGAC
CACCGAGGTCCGGGATGGCATTGATCAGCTTACGTCGCGTGCCTCCACGCCGGAAGTGGCCGAAGCGATGATCCGCGAGA
TGGCCTGGTACGACGCTTACCTGCAAAAAGGCCGGGTTGACCGCAGCGCCAACACCACGCCTGGCAACAAGAAGGGCGGC
TTGTCCAACATCGTCGAAAAAGCCATGGGCTCCATCGTCAAGTCGGGCACGGCGCCCATCAGCGGCGTGCTGTCGCCGGG
TGAAAAAGTCAGACAAAAAGGCCTGATCTACGCGGCGACGCCGGCCAGCGACTTTATCTGCGGCACGCTGCAGCTCGCTG
CCGGCATGAATCTGCATGTCTTCACGACAGGCCGCGGCACGCCATACGGCCTGGCCGAGGTACCCGTGATCAAGGTCGCG
ACACGCAGCGACCTGGCCAGGCGCTGGCACGACCTGATGGACGTGAATGCCGGCCGCATTGCCGACGGCGACGCCACCAT
CGAAGAGCTTGGCTGGGAGCTCTTCCATCTCATGCTGGAAGTTGCCAGTGGCCGCAAGAAAACCTGGGCGGAGCACTGGA
AGCTGCACAACGCGCTGGTGCTTTTCAATCCGGCACCCATTACCTGA

Upstream 100 bases:

>100_bases
GCTCGGCGTCTGTCTGCTGCTGGTGACCTACGTGCCGGCCTTCTCGCTGTGGCTGCCGGCGCTGTACAAGTAAGCGTTTT
CGTCAGAAGATAGTTTCACC

Downstream 100 bases:

>100_bases
TCCGAACCTGAGCCTCAAGTTTCAAGGAAGAATTCACATGACCCAAACCACGCCTTACCAATCCTTTCCCAACAGTTTCA
AACGCGACCTGCTGGCCGGG

Product: galactarate dehydratase

Products: NA

Alternate protein names: GalcD [H]

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MTSPNPPTQAAAKAAPQAAPGTATKRAPLYITMHDHDNVAIVANDGGLPAGTVFDSGLRLCEQVPQGHKVALVDLPKGTA
VLRYNVPIGYALKDIPAGSWVHERLLEMPSARELDNLPIATVRPPVLPPLEGYTFEGYRNPDGSVGSRNILAITTTVQCV
AGVVEFAVKRIKDELLPRFPNVDDVVGLEHTYGCGVAIDAPDAIIPIRTLRNITLNPNFGGEVMVVSLGCEKLQPERLLP
PGTIQIVDERNVADVGISAEAELDVVCLQSEHHVGFMSMIDSIMETALLHLERLDARRRETVPASELVVGVQCGGSDAFS
GVTANPAVGFATDLLVRAGATVMFSETTEVRDGIDQLTSRASTPEVAEAMIREMAWYDAYLQKGRVDRSANTTPGNKKGG
LSNIVEKAMGSIVKSGTAPISGVLSPGEKVRQKGLIYAATPASDFICGTLQLAAGMNLHVFTTGRGTPYGLAEVPVIKVA
TRSDLARRWHDLMDVNAGRIADGDATIEELGWELFHLMLEVASGRKKTWAEHWKLHNALVLFNPAPIT

Sequences:

>Translated_548_residues
MTSPNPPTQAAAKAAPQAAPGTATKRAPLYITMHDHDNVAIVANDGGLPAGTVFDSGLRLCEQVPQGHKVALVDLPKGTA
VLRYNVPIGYALKDIPAGSWVHERLLEMPSARELDNLPIATVRPPVLPPLEGYTFEGYRNPDGSVGSRNILAITTTVQCV
AGVVEFAVKRIKDELLPRFPNVDDVVGLEHTYGCGVAIDAPDAIIPIRTLRNITLNPNFGGEVMVVSLGCEKLQPERLLP
PGTIQIVDERNVADVGISAEAELDVVCLQSEHHVGFMSMIDSIMETALLHLERLDARRRETVPASELVVGVQCGGSDAFS
GVTANPAVGFATDLLVRAGATVMFSETTEVRDGIDQLTSRASTPEVAEAMIREMAWYDAYLQKGRVDRSANTTPGNKKGG
LSNIVEKAMGSIVKSGTAPISGVLSPGEKVRQKGLIYAATPASDFICGTLQLAAGMNLHVFTTGRGTPYGLAEVPVIKVA
TRSDLARRWHDLMDVNAGRIADGDATIEELGWELFHLMLEVASGRKKTWAEHWKLHNALVLFNPAPIT
>Mature_547_residues
TSPNPPTQAAAKAAPQAAPGTATKRAPLYITMHDHDNVAIVANDGGLPAGTVFDSGLRLCEQVPQGHKVALVDLPKGTAV
LRYNVPIGYALKDIPAGSWVHERLLEMPSARELDNLPIATVRPPVLPPLEGYTFEGYRNPDGSVGSRNILAITTTVQCVA
GVVEFAVKRIKDELLPRFPNVDDVVGLEHTYGCGVAIDAPDAIIPIRTLRNITLNPNFGGEVMVVSLGCEKLQPERLLPP
GTIQIVDERNVADVGISAEAELDVVCLQSEHHVGFMSMIDSIMETALLHLERLDARRRETVPASELVVGVQCGGSDAFSG
VTANPAVGFATDLLVRAGATVMFSETTEVRDGIDQLTSRASTPEVAEAMIREMAWYDAYLQKGRVDRSANTTPGNKKGGL
SNIVEKAMGSIVKSGTAPISGVLSPGEKVRQKGLIYAATPASDFICGTLQLAAGMNLHVFTTGRGTPYGLAEVPVIKVAT
RSDLARRWHDLMDVNAGRIADGDATIEELGWELFHLMLEVASGRKKTWAEHWKLHNALVLFNPAPIT

Specific function: D-galactarate metabolism; first step. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789516, Length=520, Percent_Identity=62.8846153846154, Blast_Score=687, Evalue=0.0,
Organism=Escherichia coli, GI1789475, Length=515, Percent_Identity=31.8446601941748, Blast_Score=216, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR017654
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.42 [H]

Molecular weight: Translated: 58699; Mature: 58568

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPNPPTQAAAKAAPQAAPGTATKRAPLYITMHDHDNVAIVANDGGLPAGTVFDSGLRL
CCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHH
CEQVPQGHKVALVDLPKGTAVLRYNVPIGYALKDIPAGSWVHERLLEMPSARELDNLPIA
HHHCCCCCEEEEEECCCCCEEEEECCCCCEEHHCCCCCHHHHHHHHCCCCCCCCCCCCCE
TVRPPVLPPLEGYTFEGYRNPDGSVGSRNILAITTTVQCVAGVVEFAVKRIKDELLPRFP
ECCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCC
NVDDVVGLEHTYGCGVAIDAPDAIIPIRTLRNITLNPNFGGEVMVVSLGCEKLQPERLLP
CCCHHCCCCCCCCCCEEECCCCCEEEHHHHCEEEECCCCCCCEEEEEECCCCCCCCCCCC
PGTIQIVDERNVADVGISAEAELDVVCLQSEHHVGFMSMIDSIMETALLHLERLDARRRE
CCCEEEEECCCCEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
TVPASELVVGVQCGGSDAFSGVTANPAVGFATDLLVRAGATVMFSETTEVRDGIDQLTSR
CCCHHHEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHC
ASTPEVAEAMIREMAWYDAYLQKGRVDRSANTTPGNKKGGLSNIVEKAMGSIVKSGTAPI
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
SGVLSPGEKVRQKGLIYAATPASDFICGTLQLAAGMNLHVFTTGRGTPYGLAEVPVIKVA
CCCCCCCHHHHHCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEE
TRSDLARRWHDLMDVNAGRIADGDATIEELGWELFHLMLEVASGRKKTWAEHWKLHNALV
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEE
LFNPAPIT
EECCCCCC
>Mature Secondary Structure 
TSPNPPTQAAAKAAPQAAPGTATKRAPLYITMHDHDNVAIVANDGGLPAGTVFDSGLRL
CCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHH
CEQVPQGHKVALVDLPKGTAVLRYNVPIGYALKDIPAGSWVHERLLEMPSARELDNLPIA
HHHCCCCCEEEEEECCCCCEEEEECCCCCEEHHCCCCCHHHHHHHHCCCCCCCCCCCCCE
TVRPPVLPPLEGYTFEGYRNPDGSVGSRNILAITTTVQCVAGVVEFAVKRIKDELLPRFP
ECCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCC
NVDDVVGLEHTYGCGVAIDAPDAIIPIRTLRNITLNPNFGGEVMVVSLGCEKLQPERLLP
CCCHHCCCCCCCCCCEEECCCCCEEEHHHHCEEEECCCCCCCEEEEEECCCCCCCCCCCC
PGTIQIVDERNVADVGISAEAELDVVCLQSEHHVGFMSMIDSIMETALLHLERLDARRRE
CCCEEEEECCCCEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
TVPASELVVGVQCGGSDAFSGVTANPAVGFATDLLVRAGATVMFSETTEVRDGIDQLTSR
CCCHHHEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHC
ASTPEVAEAMIREMAWYDAYLQKGRVDRSANTTPGNKKGGLSNIVEKAMGSIVKSGTAPI
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
SGVLSPGEKVRQKGLIYAATPASDFICGTLQLAAGMNLHVFTTGRGTPYGLAEVPVIKVA
CCCCCCCHHHHHCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEE
TRSDLARRWHDLMDVNAGRIADGDATIEELGWELFHLMLEVASGRKKTWAEHWKLHNALV
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEE
LFNPAPIT
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]