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The map label for this gene is livM [H]

Identifier: 91788944

GI number: 91788944

Start: 3251834

End: 3253705

Strand: Reverse

Name: livM [H]

Synonym: Bpro_3084

Alternate gene names: 91788944

Gene position: 3253705-3251834 (Counterclockwise)

Preceding gene: 91788945

Following gene: 91788943

Centisome position: 62.57

GC content: 67.15

Gene sequence:

>1872_bases
GTGACGGTTTCAGTGGTCCAGTTGCTGGGCGGGCTGTCGTATGCGACCACGCTGTTTTTGATGGCGGCGGGCCTGACGTT
GATTTTCGGCGTCACGCGCATCGTCAATTTTGCGCATGGCAGTTTCTTCATGCTGGGGGCGCTGTTCACCGCGCACTGGG
TCACCGAATGGTTTCCGGCGTGGGGCGAGAGTGCGCCCCTTTACCTGCTGGCTATTCTTTTTGGAGCTGCCTGCGCCGGG
CTGGTTGGGGCTTTAGCCGATTTTCTTCTCCTGAGAAGAATGAGCGGCGCGCCGGAGTTGTACCAGCTGGTCGCGACGTT
CGGCCTGACGCTGGCGCTGCATGACGCCATGCAGTGGGGCTTTGGCCCCGACGAGGTGTTTGCGCCGCGTTTTCCGGGGC
TCAAGGGCTCGGTGCAGATGGGTGATGAGTTCTTTCCGGTGTATCAGCTCGTGATGATTGCGCTGGGCCCGCTGGTCTGG
CTGGGCCTTCATCTGCTGCTGCGTCACTCGCTGTTTGGTCGGCGCCTGCGCGCCGCCACGCAAGACCGGTCGATGCTGGC
GGCGCTCGGCGTCAACCCCAAACCGCTGATGCTGGGAGCGGTGGTCCTCGGCTGCGCGCTGGCCGGCTTGGGCGGGGCCC
TGCAATTGCCCCGTGAACCGGCGCACCTGCAAATGGACATGAACGTGATTGTCGAGACCTTTGTCGTGGTCGTCACGGGC
GGCCTGGGCAGCATCGGGGGCGCATTTGTGGCGGCCCTGCTGATCGGCCTCGTGCATGCCCTGGGTATCGCCGTGCTGCC
GCAGGCCACGCTGGTCATCGTCTTTTTGACCATGGCGGCGGTGCTGGTGCTCAGGCCCCAGGGGCTCAATGGTCTGTCGG
TGGCTTCGCAGGAGGGCGTGCGCGAGCCGGCGCAGCGGTTTCGCGGCCTGGACCTGACGCGCTTCTGGAACGGCGCCATT
GCCGCGGTGCTGGTGCTACTGTCGGGGCTGGCCTGGCAGGGCGGGGCATACTGGCAAACGCTGGCGGCCGATGCGTTGAT
TCTGTTGATTTTTGGCATCAGCCTGCAGTCGATGATGGCGCTCGGCGGCCTGGTCAGCTTTGGCCATGCAGCTTTTTTTG
CACTGGGCGGCTATGGTGCGGCCCTGTCGCACAGCCTGTGGGGTGCATCGCTGCCGGTCGCCCTGGCGGCGGGTTGCGTG
ACGGCCCTGGTGGTCGCCGCCGTGTTTGGCGCTGCGGTGGTGCGCAGCGCCGGGGTGTACCTGGCCATGCTGTCGCTGGC
GCTGGCACAGGTGATCTGGGCCGGGGCCACCCAGTGGGTCAGCCTCACCGGAGGCGACAACGGCCTGATCGGGCTGGCCC
TGGTGGAAGAGGAGGGCCGGCCGCTGTTTTTCGCGCTGCTGGTGGTGCTGGCGCTGGCTTGCGTGTTGGCGCTGCGCCTG
CTGAGCCGGTCGGTCATGGGGGCGGCGCTGCAGGCTGTGCGCGACGCGCCCGCGCGGGCGGCCGCTTCCGGCTTGCCCGT
GGGCTGGCTCAAGTACCGCGTCTTTCTGGAGAGTGCGGTGCTGGCAGGCCTTGCCGGCGGCCTGTTTGCCGCGCACAAGG
GCGCGGTGTTTCCCTCCATCGCCGCGGTGGCTACCTCGGTGGATGCCTTGCTGGTGGTTTTGCTCGGCGGCGTTCACCAG
CTTTGGGGCGCCGTGGTGGGCAGCGCCGTGTTGAGCTATGTCAGCGCGGAGCTGGGCCGTGAAGTGACGTACTGGCGGGG
ATTGCTGGGCCTCTTCATCATGCTGGTGATGGTGGCTTCACCGTCGGGTTTGCTGGGCCTGCTGGGCAGCCGCACCCGCC
CGGCCGAGCGGGCAACCGGGAGGGCGGGCTGA

Upstream 100 bases:

>100_bases
ATGTGGCCCCCACGCTTGTCGCTTCGCGTACTGCGCGAGGCCTTGCAGGCCGCGGCTTGCGAGACGCTTCGCCTCCTATG
TGCTCCAGAGAAGTGATCGC

Downstream 100 bases:

>100_bases
TGCTGCAGGTTCAGCAACTGGTCAAGCACTTTGGCGGCATCAAGGCGGTCGATGGCGTGAGCTTTGAGGTCTCGGCAGGC
GAGTGCGTGGCCTTGATCGG

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein M [H]

Number of amino acids: Translated: 623; Mature: 622

Protein sequence:

>623_residues
MTVSVVQLLGGLSYATTLFLMAAGLTLIFGVTRIVNFAHGSFFMLGALFTAHWVTEWFPAWGESAPLYLLAILFGAACAG
LVGALADFLLLRRMSGAPELYQLVATFGLTLALHDAMQWGFGPDEVFAPRFPGLKGSVQMGDEFFPVYQLVMIALGPLVW
LGLHLLLRHSLFGRRLRAATQDRSMLAALGVNPKPLMLGAVVLGCALAGLGGALQLPREPAHLQMDMNVIVETFVVVVTG
GLGSIGGAFVAALLIGLVHALGIAVLPQATLVIVFLTMAAVLVLRPQGLNGLSVASQEGVREPAQRFRGLDLTRFWNGAI
AAVLVLLSGLAWQGGAYWQTLAADALILLIFGISLQSMMALGGLVSFGHAAFFALGGYGAALSHSLWGASLPVALAAGCV
TALVVAAVFGAAVVRSAGVYLAMLSLALAQVIWAGATQWVSLTGGDNGLIGLALVEEEGRPLFFALLVVLALACVLALRL
LSRSVMGAALQAVRDAPARAAASGLPVGWLKYRVFLESAVLAGLAGGLFAAHKGAVFPSIAAVATSVDALLVVLLGGVHQ
LWGAVVGSAVLSYVSAELGREVTYWRGLLGLFIMLVMVASPSGLLGLLGSRTRPAERATGRAG

Sequences:

>Translated_623_residues
MTVSVVQLLGGLSYATTLFLMAAGLTLIFGVTRIVNFAHGSFFMLGALFTAHWVTEWFPAWGESAPLYLLAILFGAACAG
LVGALADFLLLRRMSGAPELYQLVATFGLTLALHDAMQWGFGPDEVFAPRFPGLKGSVQMGDEFFPVYQLVMIALGPLVW
LGLHLLLRHSLFGRRLRAATQDRSMLAALGVNPKPLMLGAVVLGCALAGLGGALQLPREPAHLQMDMNVIVETFVVVVTG
GLGSIGGAFVAALLIGLVHALGIAVLPQATLVIVFLTMAAVLVLRPQGLNGLSVASQEGVREPAQRFRGLDLTRFWNGAI
AAVLVLLSGLAWQGGAYWQTLAADALILLIFGISLQSMMALGGLVSFGHAAFFALGGYGAALSHSLWGASLPVALAAGCV
TALVVAAVFGAAVVRSAGVYLAMLSLALAQVIWAGATQWVSLTGGDNGLIGLALVEEEGRPLFFALLVVLALACVLALRL
LSRSVMGAALQAVRDAPARAAASGLPVGWLKYRVFLESAVLAGLAGGLFAAHKGAVFPSIAAVATSVDALLVVLLGGVHQ
LWGAVVGSAVLSYVSAELGREVTYWRGLLGLFIMLVMVASPSGLLGLLGSRTRPAERATGRAG
>Mature_622_residues
TVSVVQLLGGLSYATTLFLMAAGLTLIFGVTRIVNFAHGSFFMLGALFTAHWVTEWFPAWGESAPLYLLAILFGAACAGL
VGALADFLLLRRMSGAPELYQLVATFGLTLALHDAMQWGFGPDEVFAPRFPGLKGSVQMGDEFFPVYQLVMIALGPLVWL
GLHLLLRHSLFGRRLRAATQDRSMLAALGVNPKPLMLGAVVLGCALAGLGGALQLPREPAHLQMDMNVIVETFVVVVTGG
LGSIGGAFVAALLIGLVHALGIAVLPQATLVIVFLTMAAVLVLRPQGLNGLSVASQEGVREPAQRFRGLDLTRFWNGAIA
AVLVLLSGLAWQGGAYWQTLAADALILLIFGISLQSMMALGGLVSFGHAAFFALGGYGAALSHSLWGASLPVALAAGCVT
ALVVAAVFGAAVVRSAGVYLAMLSLALAQVIWAGATQWVSLTGGDNGLIGLALVEEEGRPLFFALLVVLALACVLALRLL
SRSVMGAALQAVRDAPARAAASGLPVGWLKYRVFLESAVLAGLAGGLFAAHKGAVFPSIAAVATSVDALLVVLLGGVHQL
WGAVVGSAVLSYVSAELGREVTYWRGLLGLFIMLVMVASPSGLLGLLGSRTRPAERATGRAG

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=304, Percent_Identity=28.9473684210526, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1789866, Length=301, Percent_Identity=25.5813953488372, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 64648; Mature: 64517

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSVVQLLGGLSYATTLFLMAAGLTLIFGVTRIVNFAHGSFFMLGALFTAHWVTEWFPA
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
WGESAPLYLLAILFGAACAGLVGALADFLLLRRMSGAPELYQLVATFGLTLALHDAMQWG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
FGPDEVFAPRFPGLKGSVQMGDEFFPVYQLVMIALGPLVWLGLHLLLRHSLFGRRLRAAT
CCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDRSMLAALGVNPKPLMLGAVVLGCALAGLGGALQLPREPAHLQMDMNVIVETFVVVVTG
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
GLGSIGGAFVAALLIGLVHALGIAVLPQATLVIVFLTMAAVLVLRPQGLNGLSVASQEGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
REPAQRFRGLDLTRFWNGAIAAVLVLLSGLAWQGGAYWQTLAADALILLIFGISLQSMMA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGGLVSFGHAAFFALGGYGAALSHSLWGASLPVALAAGCVTALVVAAVFGAAVVRSAGVY
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAMLSLALAQVIWAGATQWVSLTGGDNGLIGLALVEEEGRPLFFALLVVLALACVLALRL
HHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
LSRSVMGAALQAVRDAPARAAASGLPVGWLKYRVFLESAVLAGLAGGLFAAHKGAVFPSI
HHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AAVATSVDALLVVLLGGVHQLWGAVVGSAVLSYVSAELGREVTYWRGLLGLFIMLVMVAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
PSGLLGLLGSRTRPAERATGRAG
CCHHHHHHCCCCCCHHHCCCCCC
>Mature Secondary Structure 
TVSVVQLLGGLSYATTLFLMAAGLTLIFGVTRIVNFAHGSFFMLGALFTAHWVTEWFPA
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC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CCHHHHHHCCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]