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The map label for this gene is bioH [C]

Identifier: 91788927

GI number: 91788927

Start: 3232961

End: 3233839

Strand: Reverse

Name: bioH [C]

Synonym: Bpro_3067

Alternate gene names: 91788927

Gene position: 3233839-3232961 (Counterclockwise)

Preceding gene: 91788929

Following gene: 91788926

Centisome position: 62.19

GC content: 63.59

Gene sequence:

>879_bases
ATGTTCGAGAGCTTTTCCTCCTCCGAGATCAATGGCCCCGCCGGTGCTCTGCGCACCTTGCGGGGAGGCCATGGGGCGCC
GCTGCTGTTGCTGCATGGCCACCCTCAAACGCATGTGATGTGGCACGCGGTGGCCGATGAACTGGCCAAGGTGTTTACCG
TGGTCCTGATGGATTTGCGTGGCTACGGCGATTCAGCCCGGGTCGGCGCCGACCCGGAACATCGCGCTTATTCCAAGCGG
GCGATGGCGCTGGATGCCGTGGCGGTGATGCGCCACCACGGCTTTGACCGCTTTCAGATACTGGCCCATGACCGTGGCGC
GCGCGTGGCGCATCGCCTTGCGGTGGACCATCCCGCCATGGTGCAACGGCTGATGCTGCTGGACATTGCACCAACGTTGG
GCATGTATGAGAACACGTCCGATGCTTTTGCACGCGCTTACTGGCACTGGTTCTTTCTGATCCAGCCGCCGCCCCTGCCG
GAAGCCCTGATCGAGTCCGATCCGGTGCGCTATGTGAGAAGCGTGATGGGCAAACGCCATGCCGGCCTCGGGGCGTTTGC
ACCGGCTGCGCTGGCCGAGTACGAACGCTGCGCGCAGATTCCCGGAACCGCCATGAGTATTTGCGAAGACTATCGGGCCT
CAGCCACGATTGACCTGGACCATGACCGCGCCGACCGAACCGCCGGCCGCCAGCTGGCGCAGCCGCTGCGCGTGCTGTGG
GGCGCGCATGGCGCCGTGGGCCAGTGCTTCGATGTGCTCGGCCTCTGGCGGGAACGTGCCAGCGACGTCTCGGGGATAAG
CCTGCCGTGCGGGCACTATATTGCGGAAGAAGCGCCAGCATTGTTGCTGGAACAAGCCCTGAATTTTTTCGAAACTTAA

Upstream 100 bases:

>100_bases
GCTGATGCGCTGGCTGCCGCATACCCGGCGCGGAGCATGCGTTTCCTGGCAGCCGGCGCAGAAAAAACCGGGTGCCGAAA
AAGAGAATCAAGGCTGACTG

Downstream 100 bases:

>100_bases
ACCAGAGGACCACATCATGAGCATCACCACGACAAACCAGGCCAGCAAGAAAAGAATCGCAGTCATCGCCGGTGACGGCA
TCGGCAAGGAAACCATGCCC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MFESFSSSEINGPAGALRTLRGGHGAPLLLLHGHPQTHVMWHAVADELAKVFTVVLMDLRGYGDSARVGADPEHRAYSKR
AMALDAVAVMRHHGFDRFQILAHDRGARVAHRLAVDHPAMVQRLMLLDIAPTLGMYENTSDAFARAYWHWFFLIQPPPLP
EALIESDPVRYVRSVMGKRHAGLGAFAPAALAEYERCAQIPGTAMSICEDYRASATIDLDHDRADRTAGRQLAQPLRVLW
GAHGAVGQCFDVLGLWRERASDVSGISLPCGHYIAEEAPALLLEQALNFFET

Sequences:

>Translated_292_residues
MFESFSSSEINGPAGALRTLRGGHGAPLLLLHGHPQTHVMWHAVADELAKVFTVVLMDLRGYGDSARVGADPEHRAYSKR
AMALDAVAVMRHHGFDRFQILAHDRGARVAHRLAVDHPAMVQRLMLLDIAPTLGMYENTSDAFARAYWHWFFLIQPPPLP
EALIESDPVRYVRSVMGKRHAGLGAFAPAALAEYERCAQIPGTAMSICEDYRASATIDLDHDRADRTAGRQLAQPLRVLW
GAHGAVGQCFDVLGLWRERASDVSGISLPCGHYIAEEAPALLLEQALNFFET
>Mature_292_residues
MFESFSSSEINGPAGALRTLRGGHGAPLLLLHGHPQTHVMWHAVADELAKVFTVVLMDLRGYGDSARVGADPEHRAYSKR
AMALDAVAVMRHHGFDRFQILAHDRGARVAHRLAVDHPAMVQRLMLLDIAPTLGMYENTSDAFARAYWHWFFLIQPPPLP
EALIESDPVRYVRSVMGKRHAGLGAFAPAALAEYERCAQIPGTAMSICEDYRASATIDLDHDRADRTAGRQLAQPLRVLW
GAHGAVGQCFDVLGLWRERASDVSGISLPCGHYIAEEAPALLLEQALNFFET

Specific function: Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has low activity towards chloroacetate [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=270, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI13376164, Length=270, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI218777837, Length=235, Percent_Identity=24.2553191489362, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17554012, Length=285, Percent_Identity=25.6140350877193, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.3 [H]

Molecular weight: Translated: 32165; Mature: 32165

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFESFSSSEINGPAGALRTLRGGHGAPLLLLHGHPQTHVMWHAVADELAKVFTVVLMDLR
CCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
GYGDSARVGADPEHRAYSKRAMALDAVAVMRHHGFDRFQILAHDRGARVAHRLAVDHPAM
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCHHH
VQRLMLLDIAPTLGMYENTSDAFARAYWHWFFLIQPPPLPEALIESDPVRYVRSVMGKRH
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEECCCCCCHHHHCCCHHHHHHHHHHHHC
AGLGAFAPAALAEYERCAQIPGTAMSICEDYRASATIDLDHDRADRTAGRQLAQPLRVLW
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHH
GAHGAVGQCFDVLGLWRERASDVSGISLPCGHYIAEEAPALLLEQALNFFET
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFESFSSSEINGPAGALRTLRGGHGAPLLLLHGHPQTHVMWHAVADELAKVFTVVLMDLR
CCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
GYGDSARVGADPEHRAYSKRAMALDAVAVMRHHGFDRFQILAHDRGARVAHRLAVDHPAM
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCHHH
VQRLMLLDIAPTLGMYENTSDAFARAYWHWFFLIQPPPLPEALIESDPVRYVRSVMGKRH
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEECCCCCCHHHHCCCHHHHHHHHHHHHC
AGLGAFAPAALAEYERCAQIPGTAMSICEDYRASATIDLDHDRADRTAGRQLAQPLRVLW
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHH
GAHGAVGQCFDVLGLWRERASDVSGISLPCGHYIAEEAPALLLEQALNFFET
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA