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The map label for this gene is hipO [H]

Identifier: 91788396

GI number: 91788396

Start: 2649822

End: 2651015

Strand: Direct

Name: hipO [H]

Synonym: Bpro_2533

Alternate gene names: 91788396

Gene position: 2649822-2651015 (Clockwise)

Preceding gene: 91788389

Following gene: 91788400

Centisome position: 50.96

GC content: 60.72

Gene sequence:

>1194_bases
ATGAAATTGATTGATCCCATCGTTGAATTCCATTCCGAACTGCAGGCCATACGACGCAATATCCATGCCCACCCGGAACT
TTGCTATGAAGAGCAGCGCACCGCCGATATCGTCGCCCAAAAACTCACCGACTGGGGCATTCCTGTCCTGCGCGGCATGG
GCGTAACCGGTGTTGTCGGCGTCATCAAGCGCGGCACCGGCACGGCGGCCATCGGCTTGCGCGCCGACATGGATGCGCTG
CCCATGCAGGAATTCAATACCTTTCCCCATGCCTCCAGGCACGACGGCAAAATGCACGCCTGCGGCCATGACGGCCATAC
CGCGATGCTGCTGGGCGCGGCGCATCACCTGGCAAAGTACGGCAACTTCGACGGCACGGTTTACCTGATTTTTCAGCCCG
CCGAAGAAGGCGGTGCCGGTGCCAAACGGATGATGGACGACGGCCTCTTCGAGCGCTGCCCGATGCAGGCGGTCTACGGC
ATGCACAACTGGCCGGGCGCGCCGGTCGGCACCTTTGGCGTGACGCCGGGGCCGATGATGGCATCGTCCAATGAATTTGA
AGTCATCGTTCGCGGCAAGGGGGCGCACGCCGCGCAACCTCACAAAGGGACGGACCCCATCATGGTGGCGGTGCAGATTG
CACAGAGCTGGCAAACCATCGTCTCGCGCAACAAGAACCCGATCGATGCGGGTGTGCTTTCCATCACGCAGATCCATGCG
GGCAGCGCGACCAATGTCATTCCCGATGATGCAACGCTGATTGGAACGGTGCGCACCTTCACCATCGAGGTGCTTGATCT
GCTGGAGCAACGCATGCGCGAGGTTGCCACCCACACGGCCGCCGCCTTTGGCGCCGGGGTTGAATTCAACTTCAAGCGCA
ATTACCCGCCGCTGATCAACCACCCCCAGCAAACCGCTTTTGCCGTTGGCGTGCTGCAACAGATTGTCGGCATCGACCAG
GTCAATGCGCAGGTCGAACCAACCATGGGCTCAGAAGATTTTGCCTTCATGCTGCAGGCCAAACCGGGCTGCTATGTATT
CATTGGCAATGGCGAGGGCGATCACCGCGACATGGGGCACGGCCTGGGCCCGTGCAATCTGCATAACCCGAGTTACGACT
TCAATGACGACCTGCTGCCAATTGGGGCGACTTACTGGGTTCGCCTGGCTGAGGCCGCGCTGCCGGCGGCTTGA

Upstream 100 bases:

>100_bases
ACATCTTGTATACCAAATCTGCTGGTAGAAGCCCTGCCTTTGCGCAAAAACCCAGCAGCAAAATCGGCAAACCCACTTTT
AGTCATTCACAGGAATAGCC

Downstream 100 bases:

>100_bases
GCAGCCCTGTCAAAGACGGCCGACCAGCGCCATGTCCGGCCGCGCCAACCAGGCCTGCCACTCATGCGCCAACTGCTGAC
TCGCTGCAGCCGCCCTGCTC

Product: peptidase M20D, amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKLIDPIVEFHSELQAIRRNIHAHPELCYEEQRTADIVAQKLTDWGIPVLRGMGVTGVVGVIKRGTGTAAIGLRADMDAL
PMQEFNTFPHASRHDGKMHACGHDGHTAMLLGAAHHLAKYGNFDGTVYLIFQPAEEGGAGAKRMMDDGLFERCPMQAVYG
MHNWPGAPVGTFGVTPGPMMASSNEFEVIVRGKGAHAAQPHKGTDPIMVAVQIAQSWQTIVSRNKNPIDAGVLSITQIHA
GSATNVIPDDATLIGTVRTFTIEVLDLLEQRMREVATHTAAAFGAGVEFNFKRNYPPLINHPQQTAFAVGVLQQIVGIDQ
VNAQVEPTMGSEDFAFMLQAKPGCYVFIGNGEGDHRDMGHGLGPCNLHNPSYDFNDDLLPIGATYWVRLAEAALPAA

Sequences:

>Translated_397_residues
MKLIDPIVEFHSELQAIRRNIHAHPELCYEEQRTADIVAQKLTDWGIPVLRGMGVTGVVGVIKRGTGTAAIGLRADMDAL
PMQEFNTFPHASRHDGKMHACGHDGHTAMLLGAAHHLAKYGNFDGTVYLIFQPAEEGGAGAKRMMDDGLFERCPMQAVYG
MHNWPGAPVGTFGVTPGPMMASSNEFEVIVRGKGAHAAQPHKGTDPIMVAVQIAQSWQTIVSRNKNPIDAGVLSITQIHA
GSATNVIPDDATLIGTVRTFTIEVLDLLEQRMREVATHTAAAFGAGVEFNFKRNYPPLINHPQQTAFAVGVLQQIVGIDQ
VNAQVEPTMGSEDFAFMLQAKPGCYVFIGNGEGDHRDMGHGLGPCNLHNPSYDFNDDLLPIGATYWVRLAEAALPAA
>Mature_397_residues
MKLIDPIVEFHSELQAIRRNIHAHPELCYEEQRTADIVAQKLTDWGIPVLRGMGVTGVVGVIKRGTGTAAIGLRADMDAL
PMQEFNTFPHASRHDGKMHACGHDGHTAMLLGAAHHLAKYGNFDGTVYLIFQPAEEGGAGAKRMMDDGLFERCPMQAVYG
MHNWPGAPVGTFGVTPGPMMASSNEFEVIVRGKGAHAAQPHKGTDPIMVAVQIAQSWQTIVSRNKNPIDAGVLSITQIHA
GSATNVIPDDATLIGTVRTFTIEVLDLLEQRMREVATHTAAAFGAGVEFNFKRNYPPLINHPQQTAFAVGVLQQIVGIDQ
VNAQVEPTMGSEDFAFMLQAKPGCYVFIGNGEGDHRDMGHGLGPCNLHNPSYDFNDDLLPIGATYWVRLAEAALPAA

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=434, Percent_Identity=28.5714285714286, Blast_Score=121, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 42887; Mature: 42887

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIDPIVEFHSELQAIRRNIHAHPELCYEEQRTADIVAQKLTDWGIPVLRGMGVTGVVG
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHH
VIKRGTGTAAIGLRADMDALPMQEFNTFPHASRHDGKMHACGHDGHTAMLLGAAHHLAKY
HHCCCCCCEEEEEECCCCCCCHHHHCCCCCCCCCCCCEEECCCCCCEEEEHHHHHHHHHH
GNFDGTVYLIFQPAEEGGAGAKRMMDDGLFERCPMQAVYGMHNWPGAPVGTFGVTPGPMM
CCCCCEEEEEEECCCCCCCHHHHHHHCCHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCC
ASSNEFEVIVRGKGAHAAQPHKGTDPIMVAVQIAQSWQTIVSRNKNPIDAGVLSITQIHA
CCCCCEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHEEEEEEEC
GSATNVIPDDATLIGTVRTFTIEVLDLLEQRMREVATHTAAAFGAGVEFNFKRNYPPLIN
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
HPQQTAFAVGVLQQIVGIDQVNAQVEPTMGSEDFAFMLQAKPGCYVFIGNGEGDHRDMGH
CCHHHHHHHHHHHHHHCHHHCCCEECCCCCCCCEEEEEECCCCEEEEEECCCCCCHHHCC
GLGPCNLHNPSYDFNDDLLPIGATYWVRLAEAALPAA
CCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLIDPIVEFHSELQAIRRNIHAHPELCYEEQRTADIVAQKLTDWGIPVLRGMGVTGVVG
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHH
VIKRGTGTAAIGLRADMDALPMQEFNTFPHASRHDGKMHACGHDGHTAMLLGAAHHLAKY
HHCCCCCCEEEEEECCCCCCCHHHHCCCCCCCCCCCCEEECCCCCCEEEEHHHHHHHHHH
GNFDGTVYLIFQPAEEGGAGAKRMMDDGLFERCPMQAVYGMHNWPGAPVGTFGVTPGPMM
CCCCCEEEEEEECCCCCCCHHHHHHHCCHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCC
ASSNEFEVIVRGKGAHAAQPHKGTDPIMVAVQIAQSWQTIVSRNKNPIDAGVLSITQIHA
CCCCCEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHEEEEEEEC
GSATNVIPDDATLIGTVRTFTIEVLDLLEQRMREVATHTAAAFGAGVEFNFKRNYPPLIN
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
HPQQTAFAVGVLQQIVGIDQVNAQVEPTMGSEDFAFMLQAKPGCYVFIGNGEGDHRDMGH
CCHHHHHHHHHHHHHHCHHHCCCEECCCCCCCCEEEEEECCCCEEEEEECCCCCCHHHCC
GLGPCNLHNPSYDFNDDLLPIGATYWVRLAEAALPAA
CCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]