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The map label for this gene is ttuC [H]

Identifier: 91787327

GI number: 91787327

Start: 1479941

End: 1481029

Strand: Direct

Name: ttuC [H]

Synonym: Bpro_1432

Alternate gene names: 91787327

Gene position: 1479941-1481029 (Clockwise)

Preceding gene: 91787326

Following gene: 91787328

Centisome position: 28.46

GC content: 64.83

Gene sequence:

>1089_bases
ATGAAAACGTACAAGATCGCGTGCATCCCCGGTGACGGCATCGGCAAGGAAGTGGTACCGGCCGGCCAGACCGTGCTCGA
AGCACTGGCCGCCACGCAGAACAAATTCAAATTCGAGTTCACCTCGTTTGACTGGGGCGGCGACTATTTCCGCCAGCACG
GCGTGATGATGCCGGAGGACGGCCTGGATGCGCTGCGCGACAAGGACGCAATCCTGTTCGGCTCCGCCGGCGACCCGCAC
ATCCCGGACCACATCACGCTGTGGGGCCTGCGCCTGAAGATCTGCCAGGGCTTTGACCAGTACGCCAACGTGCGCCCCAC
GCGCATCCTGCCCGGCATCGACGGCCCCCTGAAGCGCTGCAAGCCTGAAGACCTGAACTGGGTCATCGTGCGCGAAAACT
CCGAGGGCGAGTATTCGGGCGTCGGTGGCCGCGCCCACCAGGGCCATCCGATCGAGGTGGCCACTGATGTCTCGATGATG
ACCCGTGCCGGTGTGGAGCGCATCATGCGTTTTGCCTTCAAGCTGGCGCAATTACGCCCCCGCAAGCTGCTGACCGTGAT
CACCAAGTCCAATGCCCAGCGCCACGCCATGGTGATGTGGGACGAGATCGCCCTGCAGATCTCCAAAGAGTTCCCGGACG
TCAAATGGGACAAGGAACTGGTGGATGCCTCGACGGCGCGCATGATCAACCGCCCGGCCTCGCTCGACACCATTGTGGCA
ACCAACCTGCACGCCGACATCCTGAGCGACCTGGCCGCCGCGCTGGCCGGCAGCCTGGGCATTGCGCCCACCGGCAACAT
TGACCCCGAACGCCGCTATCCGTCGATGTTCGAGCCCATCCATGGCTCGGCCTTCGACATCATGGGCAAGGGCCTGGCCA
ACCCGGTCGGCACCTTCTGGTCCTGCGTGATGATGCTTGAACACCTCGGTGAGCCTGAGGCCGCCAGGGTGTTGATGGAT
GCCGTGGAGGCCATCACCGCCGACCCGGCGCTGCATACCGGCGACCTGGGCGGCAAGGCCACGATGGCACAGGTCACCGA
AGCCGTCTGCGCGCTTTTTGCCGCGGCCCCGGTGCGCCAGGCGGCGTGA

Upstream 100 bases:

>100_bases
TAACTTGAAGGAAATAATGAGATAACCTGAAATGTTTTACATGCGATGGGCAATCGTTAAAGTTGTCGGCAGGACAACTC
CCAACAGCCCAGGACATTTC

Downstream 100 bases:

>100_bases
CAGGCCTGACAGACCAGACGGTAAGGGCCTGACTGGCCTGATGGATGACGAGATGGCAACAATCAACAGGAGACAAACCA
TGAAACAGCTTTTAAGTGCA

Product: tartrate dehydrogenase

Products: NA

Alternate protein names: TDH; D-malate dehydrogenase [decarboxylating] [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKTYKIACIPGDGIGKEVVPAGQTVLEALAATQNKFKFEFTSFDWGGDYFRQHGVMMPEDGLDALRDKDAILFGSAGDPH
IPDHITLWGLRLKICQGFDQYANVRPTRILPGIDGPLKRCKPEDLNWVIVRENSEGEYSGVGGRAHQGHPIEVATDVSMM
TRAGVERIMRFAFKLAQLRPRKLLTVITKSNAQRHAMVMWDEIALQISKEFPDVKWDKELVDASTARMINRPASLDTIVA
TNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHGSAFDIMGKGLANPVGTFWSCVMMLEHLGEPEAARVLMD
AVEAITADPALHTGDLGGKATMAQVTEAVCALFAAAPVRQAA

Sequences:

>Translated_362_residues
MKTYKIACIPGDGIGKEVVPAGQTVLEALAATQNKFKFEFTSFDWGGDYFRQHGVMMPEDGLDALRDKDAILFGSAGDPH
IPDHITLWGLRLKICQGFDQYANVRPTRILPGIDGPLKRCKPEDLNWVIVRENSEGEYSGVGGRAHQGHPIEVATDVSMM
TRAGVERIMRFAFKLAQLRPRKLLTVITKSNAQRHAMVMWDEIALQISKEFPDVKWDKELVDASTARMINRPASLDTIVA
TNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHGSAFDIMGKGLANPVGTFWSCVMMLEHLGEPEAARVLMD
AVEAITADPALHTGDLGGKATMAQVTEAVCALFAAAPVRQAA
>Mature_362_residues
MKTYKIACIPGDGIGKEVVPAGQTVLEALAATQNKFKFEFTSFDWGGDYFRQHGVMMPEDGLDALRDKDAILFGSAGDPH
IPDHITLWGLRLKICQGFDQYANVRPTRILPGIDGPLKRCKPEDLNWVIVRENSEGEYSGVGGRAHQGHPIEVATDVSMM
TRAGVERIMRFAFKLAQLRPRKLLTVITKSNAQRHAMVMWDEIALQISKEFPDVKWDKELVDASTARMINRPASLDTIVA
TNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHGSAFDIMGKGLANPVGTFWSCVMMLEHLGEPEAARVLMD
AVEAITADPALHTGDLGGKATMAQVTEAVCALFAAAPVRQAA

Specific function: Unknown

COG id: COG0473

COG function: function code CE; Isocitrate/isopropylmalate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isocitrate and isopropylmalate dehydrogenases family [H]

Homologues:

Organism=Homo sapiens, GI5031777, Length=345, Percent_Identity=32.463768115942, Blast_Score=171, Evalue=7e-43,
Organism=Homo sapiens, GI4758582, Length=348, Percent_Identity=27.2988505747126, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI28178816, Length=355, Percent_Identity=25.9154929577465, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI28178821, Length=353, Percent_Identity=24.6458923512748, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI28178838, Length=323, Percent_Identity=27.2445820433437, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI28178819, Length=194, Percent_Identity=26.2886597938144, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1788101, Length=359, Percent_Identity=47.3537604456825, Blast_Score=337, Evalue=6e-94,
Organism=Escherichia coli, GI87081683, Length=356, Percent_Identity=32.8651685393258, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1787381, Length=366, Percent_Identity=28.1420765027322, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71986051, Length=347, Percent_Identity=33.1412103746398, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25144293, Length=349, Percent_Identity=27.2206303724928, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17550882, Length=353, Percent_Identity=28.6118980169972, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17505779, Length=345, Percent_Identity=25.5072463768116, Blast_Score=130, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6322097, Length=363, Percent_Identity=36.3636363636364, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6324709, Length=350, Percent_Identity=34.2857142857143, Blast_Score=179, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6319830, Length=363, Percent_Identity=31.404958677686, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324291, Length=356, Percent_Identity=30.6179775280899, Blast_Score=145, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24643270, Length=350, Percent_Identity=32.5714285714286, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24643268, Length=350, Percent_Identity=32.5714285714286, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24661184, Length=350, Percent_Identity=30.8571428571429, Blast_Score=154, Evalue=7e-38,
Organism=Drosophila melanogaster, GI281362242, Length=345, Percent_Identity=27.2463768115942, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24648872, Length=345, Percent_Identity=27.2463768115942, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI161078633, Length=263, Percent_Identity=28.1368821292776, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24650122, Length=263, Percent_Identity=28.1368821292776, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI161078639, Length=263, Percent_Identity=28.1368821292776, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI161078635, Length=262, Percent_Identity=28.2442748091603, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI161078637, Length=262, Percent_Identity=28.2442748091603, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI20130355, Length=350, Percent_Identity=26.2857142857143, Blast_Score=116, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019818
- InterPro:   IPR001804
- InterPro:   IPR011829 [H]

Pfam domain/function: PF00180 Iso_dh [H]

EC number: =1.1.1.93; =4.1.1.73; =1.1.1.83 [H]

Molecular weight: Translated: 39419; Mature: 39419

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00470 IDH_IMDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYKIACIPGDGIGKEVVPAGQTVLEALAATQNKFKFEFTSFDWGGDYFRQHGVMMPED
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCCCCC
GLDALRDKDAILFGSAGDPHIPDHITLWGLRLKICQGFDQYANVRPTRILPGIDGPLKRC
CHHHHHCCCEEEECCCCCCCCCCCEEHHHHHHHHHHCHHHHHCCCCCEECCCCCCHHHHC
KPEDLNWVIVRENSEGEYSGVGGRAHQGHPIEVATDVSMMTRAGVERIMRFAFKLAQLRP
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCH
RKLLTVITKSNAQRHAMVMWDEIALQISKEFPDVKWDKELVDASTARMINRPASLDTIVA
HHHEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHE
TNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHGSAFDIMGKGLANPVGTFW
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHCCCCCCHHHHHHCCCCCHHHHHH
SCVMMLEHLGEPEAARVLMDAVEAITADPALHTGDLGGKATMAQVTEAVCALFAAAPVRQ
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AA
CC
>Mature Secondary Structure
MKTYKIACIPGDGIGKEVVPAGQTVLEALAATQNKFKFEFTSFDWGGDYFRQHGVMMPED
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCCCCC
GLDALRDKDAILFGSAGDPHIPDHITLWGLRLKICQGFDQYANVRPTRILPGIDGPLKRC
CHHHHHCCCEEEECCCCCCCCCCCEEHHHHHHHHHHCHHHHHCCCCCEECCCCCCHHHHC
KPEDLNWVIVRENSEGEYSGVGGRAHQGHPIEVATDVSMMTRAGVERIMRFAFKLAQLRP
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCH
RKLLTVITKSNAQRHAMVMWDEIALQISKEFPDVKWDKELVDASTARMINRPASLDTIVA
HHHEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHE
TNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHGSAFDIMGKGLANPVGTFW
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHCCCCCCHHHHHHCCCCCHHHHHH
SCVMMLEHLGEPEAARVLMDAVEAITADPALHTGDLGGKATMAQVTEAVCALFAAAPVRQ
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]