Click here to switch to the map view.

The map label for this gene is livH [H]

Identifier: 91787289

GI number: 91787289

Start: 1431534

End: 1433108

Strand: Direct

Name: livH [H]

Synonym: Bpro_1394

Alternate gene names: 91787289

Gene position: 1431534-1433108 (Clockwise)

Preceding gene: 91787288

Following gene: 91787290

Centisome position: 27.53

GC content: 63.87

Gene sequence:

>1575_bases
ATGATGATTCGCTTCTCATTTTTATTCGCTACGTTTTTAATAGCTGCCAGCGCCCATGCCTTGAGCCTGGACGAGGTCAA
AGGCATGGCCATCGGGGAGACCGAAAGCCGTGTCGAAGCGCTGAACAAGGCGGCTGTGGCGGCGGACGAGAAAACCGCCG
CCTTCATCCAGGCCATGGCCGACGATGCCGTCAAAACTGCCGGCGACAAGGTGTTTGTGATCAAGGACGACAAAGGCTTC
GACCCGGTCACCGGCGCCGAGCTGGCCCTGCCGGCCGACGCCGAAGACGTGATTAACAACAACATGATGCGCGGCGAGCT
GGACACGGCGTTGGCCGCGCTGAAGCTGTTCTCCAAAGAAGAGAACGTGCGCCGCGATGCCATCAAGACCCTTTCGGGCG
GCAGCGACGAAGCCCGCTTGCCGCTGATTGAAAAAGCCTATGCGGCCGAAACTGTGCCGGCGCTGAAAAGCCAGCTGGAG
CTGGTGCGCGCCGCCATCCTGCTGGGCAGCACGGACAGGGCCAAACGCCTGGAAGCCGCGGCGCAGCTTGCCACCAGCAA
CAACCCCAACACCAAGACCGTGCTGATCGAACGCCTGGGCAGCGAGGAAGATGCCGACGTCAAGGTGGCGCTGCAGGCCG
CGCTGGCCAAGGTGGAGGCTTCACTGGCCTGGGGCGACAAGCTGGGCGCGATTTTCAGCGGCATCAGCCTGGGCAGCATT
TTGCTGCTGGTGGCGCTGGGCCTGGCGATCACCTATGGCCTCATGGGCGTCATCAACATGGCGCACGGCGAGCTGATGAT
GATTGGCGCCTACGCCACCTACGTGGTGCAGGGCCTGTTCCAGAAGTATTTGCCCGGCGCGTTTGACTGGTACCTGCTGG
CCGCCGTGCCGGTGGCCTTCCTGGCGTCGGCGCTGATGGGCGCGGCGCTGGAGCGCAGCGTGATCCGCTTCCTGTATGGC
CGCCCGCTCGAAACATTGCTGGCCACCTGGGGTATCAGCCTGATGCTGCAGCAGCTGGTGCGCTCCATCTTCGGCGCGCA
AAACGTCGGCGTGGAAAACCCGGTGTGGATGAGCGGCGGCGTGCAGGTGCTGGGCAATCTCTCGCTGCCCTACAACCGGC
TGGTCATCATCGGCTTTGCCATTGCCGTGCTGCTGGGCATGGCCTGGCTGATCAGCAGGACGCGGCTGGGCCTGTTTGTG
CGCGGCGTCACGCAAAACCGGCCCATTGCCTCGTGCATGGGCGTGAACACGGCACGGGTGGACACCTACGCGTTTGCGCT
GGGATCGGGCATTGCCGGGCTGGCGGGCTGCGCGCTGAGCCAGGTCGGCAATGTGGGGCCGGACCTGGGGCAGGGCTATA
TCGTGGATTCGTTCATGGTGGTGGTGCTGGGCGGCGTGGGCCAGCTGGCCGGCACGGTGTATGCCGCGATGGGCCTGGGC
ATCCTGAATAAATTCCTCGAAGGCTGGACGGGCGCGGTGCTGGCCAAGATTGCCGTGCTGGTGTTCATCATCATCTTCAT
CCAGAAGCGGCCGCAGGGCATCTTTGCGATGAAGGGCCGGAGTGCCGAGGCATGA

Upstream 100 bases:

>100_bases
TTTTTGAGCTATCCCGGTGCATGGTTTTCAAGGAAGTTGCAGTCTGGGCATGGCGATAGCGGGCATCGGCTGGCCGCTGT
GCCAACCCCAGGTTCTTCTC

Downstream 100 bases:

>100_bases
ACATGAGAATGCCAATCCCCATGCCCACCATCGTGCACCTTCCGGCCAAAGGCCCTTTGCTTACCCGCGCCGGCTGGAGC
GCTTTCATGATTGCGCTCAT

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MMIRFSFLFATFLIAASAHALSLDEVKGMAIGETESRVEALNKAAVAADEKTAAFIQAMADDAVKTAGDKVFVIKDDKGF
DPVTGAELALPADAEDVINNNMMRGELDTALAALKLFSKEENVRRDAIKTLSGGSDEARLPLIEKAYAAETVPALKSQLE
LVRAAILLGSTDRAKRLEAAAQLATSNNPNTKTVLIERLGSEEDADVKVALQAALAKVEASLAWGDKLGAIFSGISLGSI
LLLVALGLAITYGLMGVINMAHGELMMIGAYATYVVQGLFQKYLPGAFDWYLLAAVPVAFLASALMGAALERSVIRFLYG
RPLETLLATWGISLMLQQLVRSIFGAQNVGVENPVWMSGGVQVLGNLSLPYNRLVIIGFAIAVLLGMAWLISRTRLGLFV
RGVTQNRPIASCMGVNTARVDTYAFALGSGIAGLAGCALSQVGNVGPDLGQGYIVDSFMVVVLGGVGQLAGTVYAAMGLG
ILNKFLEGWTGAVLAKIAVLVFIIIFIQKRPQGIFAMKGRSAEA

Sequences:

>Translated_524_residues
MMIRFSFLFATFLIAASAHALSLDEVKGMAIGETESRVEALNKAAVAADEKTAAFIQAMADDAVKTAGDKVFVIKDDKGF
DPVTGAELALPADAEDVINNNMMRGELDTALAALKLFSKEENVRRDAIKTLSGGSDEARLPLIEKAYAAETVPALKSQLE
LVRAAILLGSTDRAKRLEAAAQLATSNNPNTKTVLIERLGSEEDADVKVALQAALAKVEASLAWGDKLGAIFSGISLGSI
LLLVALGLAITYGLMGVINMAHGELMMIGAYATYVVQGLFQKYLPGAFDWYLLAAVPVAFLASALMGAALERSVIRFLYG
RPLETLLATWGISLMLQQLVRSIFGAQNVGVENPVWMSGGVQVLGNLSLPYNRLVIIGFAIAVLLGMAWLISRTRLGLFV
RGVTQNRPIASCMGVNTARVDTYAFALGSGIAGLAGCALSQVGNVGPDLGQGYIVDSFMVVVLGGVGQLAGTVYAAMGLG
ILNKFLEGWTGAVLAKIAVLVFIIIFIQKRPQGIFAMKGRSAEA
>Mature_524_residues
MMIRFSFLFATFLIAASAHALSLDEVKGMAIGETESRVEALNKAAVAADEKTAAFIQAMADDAVKTAGDKVFVIKDDKGF
DPVTGAELALPADAEDVINNNMMRGELDTALAALKLFSKEENVRRDAIKTLSGGSDEARLPLIEKAYAAETVPALKSQLE
LVRAAILLGSTDRAKRLEAAAQLATSNNPNTKTVLIERLGSEEDADVKVALQAALAKVEASLAWGDKLGAIFSGISLGSI
LLLVALGLAITYGLMGVINMAHGELMMIGAYATYVVQGLFQKYLPGAFDWYLLAAVPVAFLASALMGAALERSVIRFLYG
RPLETLLATWGISLMLQQLVRSIFGAQNVGVENPVWMSGGVQVLGNLSLPYNRLVIIGFAIAVLLGMAWLISRTRLGLFV
RGVTQNRPIASCMGVNTARVDTYAFALGSGIAGLAGCALSQVGNVGPDLGQGYIVDSFMVVVLGGVGQLAGTVYAAMGLG
ILNKFLEGWTGAVLAKIAVLVFIIIFIQKRPQGIFAMKGRSAEA

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=299, Percent_Identity=28.0936454849498, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 55325; Mature: 55325

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIRFSFLFATFLIAASAHALSLDEVKGMAIGETESRVEALNKAAVAADEKTAAFIQAMA
CEEEHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
DDAVKTAGDKVFVIKDDKGFDPVTGAELALPADAEDVINNNMMRGELDTALAALKLFSKE
HHHHHHCCCEEEEEECCCCCCCCCCCCEECCCCHHHHHCCCCCCCHHHHHHHHHHHHHHH
ENVRRDAIKTLSGGSDEARLPLIEKAYAAETVPALKSQLELVRAAILLGSTDRAKRLEAA
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AQLATSNNPNTKTVLIERLGSEEDADVKVALQAALAKVEASLAWGDKLGAIFSGISLGSI
HHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLVALGLAITYGLMGVINMAHGELMMIGAYATYVVQGLFQKYLPGAFDWYLLAAVPVAF
HHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LASALMGAALERSVIRFLYGRPLETLLATWGISLMLQQLVRSIFGAQNVGVENPVWMSGG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCC
VQVLGNLSLPYNRLVIIGFAIAVLLGMAWLISRTRLGLFVRGVTQNRPIASCMGVNTARV
HHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHCCCHHHH
DTYAFALGSGIAGLAGCALSQVGNVGPDLGQGYIVDSFMVVVLGGVGQLAGTVYAAMGLG
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ILNKFLEGWTGAVLAKIAVLVFIIIFIQKRPQGIFAMKGRSAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure
MMIRFSFLFATFLIAASAHALSLDEVKGMAIGETESRVEALNKAAVAADEKTAAFIQAMA
CEEEHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
DDAVKTAGDKVFVIKDDKGFDPVTGAELALPADAEDVINNNMMRGELDTALAALKLFSKE
HHHHHHCCCEEEEEECCCCCCCCCCCCEECCCCHHHHHCCCCCCCHHHHHHHHHHHHHHH
ENVRRDAIKTLSGGSDEARLPLIEKAYAAETVPALKSQLELVRAAILLGSTDRAKRLEAA
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AQLATSNNPNTKTVLIERLGSEEDADVKVALQAALAKVEASLAWGDKLGAIFSGISLGSI
HHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLVALGLAITYGLMGVINMAHGELMMIGAYATYVVQGLFQKYLPGAFDWYLLAAVPVAF
HHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LASALMGAALERSVIRFLYGRPLETLLATWGISLMLQQLVRSIFGAQNVGVENPVWMSGG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCC
VQVLGNLSLPYNRLVIIGFAIAVLLGMAWLISRTRLGLFVRGVTQNRPIASCMGVNTARV
HHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHCCCHHHH
DTYAFALGSGIAGLAGCALSQVGNVGPDLGQGYIVDSFMVVVLGGVGQLAGTVYAAMGLG
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ILNKFLEGWTGAVLAKIAVLVFIIIFIQKRPQGIFAMKGRSAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]