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The map label for this gene is qacA [H]

Identifier: 91787264

GI number: 91787264

Start: 1408245

End: 1409774

Strand: Direct

Name: qacA [H]

Synonym: Bpro_1369

Alternate gene names: 91787264

Gene position: 1408245-1409774 (Clockwise)

Preceding gene: 91787263

Following gene: 91787269

Centisome position: 27.08

GC content: 66.47

Gene sequence:

>1530_bases
ATGAGTGATACCGCCGGGACACCCAGGGCCACACGGCGCGAGTGGATTGGGCTTGCCGTCATTGCGCTGCCGTGCCTGCT
GTACTCCATGGACCTGACGGTCATGAACCTCGCGGTGCCGCACATCAGCGCAGATCTCAAGCCCACGGGCGCGCAACTGC
TGTGGATGGTGGACATCTACGGCTTCATGATTGCCGGCTCGCTGATCACCATGGGCACGCTGGGCGACCGCATTGGCCGG
CGCCGGCTGCTGCTGATGGGGGCTGCCGCGTTTGGCATTGCCTCGGTGCTGGCGGCGCTCTCGACCACTGCCGGGATGCT
GATCGCCACGCGCGCGCTGCTCGGCCTTGCCGGGGCGACGCTGGCGCCTTCCACGCTTTCGCTGATCCGCAACATGTTTC
CCAATCCGGAGCAGCGCACGGTCGCCATCGGCGTGTGGATCACTAGTTATTCGACCGGCGGTGCGATAGGCCCCCTGGTC
GGCGGCCTGCTGCTGGAGCATTTTTGGTGGGGTTCAGTGTTCCTCGTCAGCGTGCCGGTGATGGTGTTGCTGCTGGTGCT
GGGCCCCGCGCTGCTGCCCGAATACCGCGATGCCGACGCGGGGCCGCTTGACCTGCCGAGTGCTGTGCAGTCGCTCGCTG
CCGTGCTGGCTGTGATCTACGGCCTCAAGCGCATCGCCGAGGACGGTGTGGGTTGGCTGCCCGCCGTGTGTATCCTGGCG
GGGCTGGCCATTGGCGCGGCGTTCTTGCGCAGACAGCGCACGCTGACCAGCCCGCTGATCGACCTGGCGCTGTTCCGCGC
GCCGGCTTTCAGTGCGGCCCTGGTCATCAACACCCTCTCTTTCTTCGGCGCGTTCGGGGCTTTTCTTTTTATCGCGCAGT
ATTTGCAACTGGTGATCGGGCTTTCGCCCCTGCAGGCGGGCCTGTGGTCGGTGCCTTCGGCGCTTGGTTTCATCGTCGGT
TCCATGCTGGTGCCGCTGATCGTGCGACACATCTCTTCGGGCCTGGCGGTCGTGGCTGCCCTGGCGCTTTCGGTCGTCGG
CTTCGGTGTGCTCACGCAGGTGGGCGGCGCCTCCGGGCTGACCATCCTGGTGACCGGTTCGGTTATCTTTTCGCTTGGTC
TGGCGCCGGTGGTTACGCTGGGCACCGACCTGATTGTCGGCTCTGCGCCGCCCGGGCGCGCCGGCGCAGCAGCGGCGATT
TCAGAGACCAGTTCCGAATTTGGCGGTGCACTGGGCATCGCAGTGCTGGGCAGCGTCGTAACGGCCGTGTACAGCCATGC
CATGGCCGATACCGTTCTCAGCGGTGTACCACCCGCCGCCATGCAGACGGTGCGTAGCACGCTGGGCGGCGCCGTGGCCG
TGGCCGCGGAGTTGCCCGGCACCAGCGGCGCAGCGCTGCTCGATACCTCGCGTGACGCGTTTGCCCAGGCATTTCAGGTA
ACGGCCACGATCAGCGCGGCCCTGCTGCTGGCAACTACCATTCTGGCTGCCGTCATGCTGCGGCAGACGCGCACCAGTGC
AGTGGGCTAA

Upstream 100 bases:

>100_bases
CGTGGGTGCGCCACCACGACAAATATGACAACTATGAAGGGGCGCCCAAGCCGGCCGCGCAGGCTGCCCCAGCCTGCTGC
CATGCGGACGCCAGCGCCGC

Downstream 100 bases:

>100_bases
CGCCAATACGGTTCAGTCAAGCCCTTGCCCCTGGTTTGTCATCCGGACTTGATCCGGGATCCATGGATGGCGGGCCAAGC
CCGCCATGACAAGCCAAGGT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MSDTAGTPRATRREWIGLAVIALPCLLYSMDLTVMNLAVPHISADLKPTGAQLLWMVDIYGFMIAGSLITMGTLGDRIGR
RRLLLMGAAAFGIASVLAALSTTAGMLIATRALLGLAGATLAPSTLSLIRNMFPNPEQRTVAIGVWITSYSTGGAIGPLV
GGLLLEHFWWGSVFLVSVPVMVLLLVLGPALLPEYRDADAGPLDLPSAVQSLAAVLAVIYGLKRIAEDGVGWLPAVCILA
GLAIGAAFLRRQRTLTSPLIDLALFRAPAFSAALVINTLSFFGAFGAFLFIAQYLQLVIGLSPLQAGLWSVPSALGFIVG
SMLVPLIVRHISSGLAVVAALALSVVGFGVLTQVGGASGLTILVTGSVIFSLGLAPVVTLGTDLIVGSAPPGRAGAAAAI
SETSSEFGGALGIAVLGSVVTAVYSHAMADTVLSGVPPAAMQTVRSTLGGAVAVAAELPGTSGAALLDTSRDAFAQAFQV
TATISAALLLATTILAAVMLRQTRTSAVG

Sequences:

>Translated_509_residues
MSDTAGTPRATRREWIGLAVIALPCLLYSMDLTVMNLAVPHISADLKPTGAQLLWMVDIYGFMIAGSLITMGTLGDRIGR
RRLLLMGAAAFGIASVLAALSTTAGMLIATRALLGLAGATLAPSTLSLIRNMFPNPEQRTVAIGVWITSYSTGGAIGPLV
GGLLLEHFWWGSVFLVSVPVMVLLLVLGPALLPEYRDADAGPLDLPSAVQSLAAVLAVIYGLKRIAEDGVGWLPAVCILA
GLAIGAAFLRRQRTLTSPLIDLALFRAPAFSAALVINTLSFFGAFGAFLFIAQYLQLVIGLSPLQAGLWSVPSALGFIVG
SMLVPLIVRHISSGLAVVAALALSVVGFGVLTQVGGASGLTILVTGSVIFSLGLAPVVTLGTDLIVGSAPPGRAGAAAAI
SETSSEFGGALGIAVLGSVVTAVYSHAMADTVLSGVPPAAMQTVRSTLGGAVAVAAELPGTSGAALLDTSRDAFAQAFQV
TATISAALLLATTILAAVMLRQTRTSAVG
>Mature_508_residues
SDTAGTPRATRREWIGLAVIALPCLLYSMDLTVMNLAVPHISADLKPTGAQLLWMVDIYGFMIAGSLITMGTLGDRIGRR
RLLLMGAAAFGIASVLAALSTTAGMLIATRALLGLAGATLAPSTLSLIRNMFPNPEQRTVAIGVWITSYSTGGAIGPLVG
GLLLEHFWWGSVFLVSVPVMVLLLVLGPALLPEYRDADAGPLDLPSAVQSLAAVLAVIYGLKRIAEDGVGWLPAVCILAG
LAIGAAFLRRQRTLTSPLIDLALFRAPAFSAALVINTLSFFGAFGAFLFIAQYLQLVIGLSPLQAGLWSVPSALGFIVGS
MLVPLIVRHISSGLAVVAALALSVVGFGVLTQVGGASGLTILVTGSVIFSLGLAPVVTLGTDLIVGSAPPGRAGAAAAIS
ETSSEFGGALGIAVLGSVVTAVYSHAMADTVLSGVPPAAMQTVRSTLGGAVAVAAELPGTSGAALLDTSRDAFAQAFQVT
ATISAALLLATTILAAVMLRQTRTSAVG

Specific function: Confers export-mediated resistance against antiseptic and disinfectant compounds such as intercalating dyes, quaternary ammonium salts and diamidines [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=392, Percent_Identity=30.3571428571429, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789042, Length=446, Percent_Identity=26.9058295964126, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1788710, Length=322, Percent_Identity=27.639751552795, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1790195, Length=334, Percent_Identity=25.4491017964072, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788392, Length=346, Percent_Identity=28.9017341040462, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790146, Length=181, Percent_Identity=27.6243093922652, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51790; Mature: 51659

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTAGTPRATRREWIGLAVIALPCLLYSMDLTVMNLAVPHISADLKPTGAQLLWMVDIY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
GFMIAGSLITMGTLGDRIGRRRLLLMGAAAFGIASVLAALSTTAGMLIATRALLGLAGAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LAPSTLSLIRNMFPNPEQRTVAIGVWITSYSTGGAIGPLVGGLLLEHFWWGSVFLVSVPV
CCHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MVLLLVLGPALLPEYRDADAGPLDLPSAVQSLAAVLAVIYGLKRIAEDGVGWLPAVCILA
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GLAIGAAFLRRQRTLTSPLIDLALFRAPAFSAALVINTLSFFGAFGAFLFIAQYLQLVIG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LSPLQAGLWSVPSALGFIVGSMLVPLIVRHISSGLAVVAALALSVVGFGVLTQVGGASGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TILVTGSVIFSLGLAPVVTLGTDLIVGSAPPGRAGAAAAISETSSEFGGALGIAVLGSVV
EEEEEHHHHHHHHHHHHHHHCCHHEECCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHH
TAVYSHAMADTVLSGVPPAAMQTVRSTLGGAVAVAAELPGTSGAALLDTSRDAFAQAFQV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCHHHHHHHHHH
TATISAALLLATTILAAVMLRQTRTSAVG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDTAGTPRATRREWIGLAVIALPCLLYSMDLTVMNLAVPHISADLKPTGAQLLWMVDIY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
GFMIAGSLITMGTLGDRIGRRRLLLMGAAAFGIASVLAALSTTAGMLIATRALLGLAGAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LAPSTLSLIRNMFPNPEQRTVAIGVWITSYSTGGAIGPLVGGLLLEHFWWGSVFLVSVPV
CCHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MVLLLVLGPALLPEYRDADAGPLDLPSAVQSLAAVLAVIYGLKRIAEDGVGWLPAVCILA
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GLAIGAAFLRRQRTLTSPLIDLALFRAPAFSAALVINTLSFFGAFGAFLFIAQYLQLVIG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LSPLQAGLWSVPSALGFIVGSMLVPLIVRHISSGLAVVAALALSVVGFGVLTQVGGASGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TILVTGSVIFSLGLAPVVTLGTDLIVGSAPPGRAGAAAAISETSSEFGGALGIAVLGSVV
EEEEEHHHHHHHHHHHHHHHCCHHEECCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHH
TAVYSHAMADTVLSGVPPAAMQTVRSTLGGAVAVAAELPGTSGAALLDTSRDAFAQAFQV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCHHHHHHHHHH
TATISAALLLATTILAAVMLRQTRTSAVG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]