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The map label for this gene is pyrR [H]

Identifier: 91787041

GI number: 91787041

Start: 1186723

End: 1187229

Strand: Direct

Name: pyrR [H]

Synonym: Bpro_1144

Alternate gene names: 91787041

Gene position: 1186723-1187229 (Clockwise)

Preceding gene: 91787040

Following gene: 91787042

Centisome position: 22.82

GC content: 66.07

Gene sequence:

>507_bases
ATGAGCAGTCTGACCCTGGATGCCGAGGCGCTGTATGGCGATTTGCTGCGCGGCATGCGGCTGCAGCTGGCCGCCTATGC
CCAGCCACCCCGGCTGGTGGGGGTCGCCTCCGGTGGTGCCTGGCTGGCACAGCGCCTGCAAAAAGACCTCGGCCTGACCG
GGGAGGCCGGCATTCTTTCATCGTCCATGCATCGCGACGATTTTTCGCAACGCGGCCTGGCCTCCAGTGGCCAAACCCTG
TTGCCATTCGATGTCAACGGCGCCCACCTTATCGTGGTCGACGATGTGCTCTACACCGGCCGCACGATCAGGGCGGTGCT
CAATGAGCTGTTTGACTATGGCCGGCCGGCCAGCGTCAGGCTGGTGGTCCTGGTCGATCGGGGCGGGCGCGAGCTGCCGG
TTCAACCCGATCTGGCCATTGCGCGGGTGGCCTTGCCGGCCTCGCAGACGCTGGAGCTCGCGCGCGCGGACAACGGCCAG
CTCAGTTTTCAGGTCCAGGACCGCTAA

Upstream 100 bases:

>100_bases
ACGAGCGCTACAGCACGACAGAAGCCCTGGCCGGCGGCGCTGCGGACGCCGATGCCGCATCGGCGTGCATTATTCTCGAA
CAGTTTTTAAGGAGCCTTCC

Downstream 100 bases:

>100_bases
GCCAGAGAAGAACCCCAGCAAAAATCCAGAGCGCAAGAGGAGCCCAGAGCGTGTTGTACCGACGAAACCCACAACTCAAT
AAAAATGGTGAACTGATTCA

Product: phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MSSLTLDAEALYGDLLRGMRLQLAAYAQPPRLVGVASGGAWLAQRLQKDLGLTGEAGILSSSMHRDDFSQRGLASSGQTL
LPFDVNGAHLIVVDDVLYTGRTIRAVLNELFDYGRPASVRLVVLVDRGGRELPVQPDLAIARVALPASQTLELARADNGQ
LSFQVQDR

Sequences:

>Translated_168_residues
MSSLTLDAEALYGDLLRGMRLQLAAYAQPPRLVGVASGGAWLAQRLQKDLGLTGEAGILSSSMHRDDFSQRGLASSGQTL
LPFDVNGAHLIVVDDVLYTGRTIRAVLNELFDYGRPASVRLVVLVDRGGRELPVQPDLAIARVALPASQTLELARADNGQ
LSFQVQDR
>Mature_167_residues
SSLTLDAEALYGDLLRGMRLQLAAYAQPPRLVGVASGGAWLAQRLQKDLGLTGEAGILSSSMHRDDFSQRGLASSGQTLL
PFDVNGAHLIVVDDVLYTGRTIRAVLNELFDYGRPASVRLVVLVDRGGRELPVQPDLAIARVALPASQTLELARADNGQL
SFQVQDR

Specific function: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 18082; Mature: 17951

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLTLDAEALYGDLLRGMRLQLAAYAQPPRLVGVASGGAWLAQRLQKDLGLTGEAGILS
CCCCCCHHHHHHHHHHHHHHEEEEECCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCHHC
SSMHRDDFSQRGLASSGQTLLPFDVNGAHLIVVDDVLYTGRTIRAVLNELFDYGRPASVR
CHHCCCCHHHCCCCCCCCEEEEEECCCEEEEEECCCHHCCHHHHHHHHHHHHCCCCCCEE
LVVLVDRGGRELPVQPDLAIARVALPASQTLELARADNGQLSFQVQDR
EEEEECCCCCCCCCCCCCEEEEEECCCHHHHHEEECCCCEEEEEEECC
>Mature Secondary Structure 
SSLTLDAEALYGDLLRGMRLQLAAYAQPPRLVGVASGGAWLAQRLQKDLGLTGEAGILS
CCCCCHHHHHHHHHHHHHHEEEEECCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCHHC
SSMHRDDFSQRGLASSGQTLLPFDVNGAHLIVVDDVLYTGRTIRAVLNELFDYGRPASVR
CHHCCCCHHHCCCCCCCCEEEEEECCCEEEEEECCCHHCCHHHHHHHHHHHHCCCCCCEE
LVVLVDRGGRELPVQPDLAIARVALPASQTLELARADNGQLSFQVQDR
EEEEECCCCCCCCCCCCCEEEEEECCCHHHHHEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]