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The map label for this gene is murG

Identifier: 91786973

GI number: 91786973

Start: 1107726

End: 1108889

Strand: Direct

Name: murG

Synonym: Bpro_1075

Alternate gene names: 91786973

Gene position: 1107726-1108889 (Clockwise)

Preceding gene: 91786972

Following gene: 91786974

Centisome position: 21.3

GC content: 65.81

Gene sequence:

>1164_bases
ATGAGCGAGCATGTGCGTAGCGCCGGGCCGCCCCAAGCAAGCACGGCCCCCTCGGGGGGCAGCGCAGTACACGAAGTGAC
AAGCGTGGGGGCTCGCGTAGCTTTGGTGATGGCCGGCGGAACCGGGGGGCATATCTTCCCGGGCCTCGCCGTGGCCGAGG
CCCTGCGCGAGCGCGGCTGGCGGGTGCACTGGCTGGGCGGCCGGGGCAATGCGGGTCACCCCAGCATGGAAAGCCAGCTG
GTGCCACCACGCGGCTTCGCTTTCGAGTCAATCGATTTCTCCGGCGTGCGCGGCAAGGGCCCGCTCACCCTGGTGTTCCT
GCCGCTGCGCCTGCTCAAGGCCTTTTGGCAGAGCATCCAGGTTGTACGGCGCGTCAAGCCTGATGTGGTGGTCGGGCTGG
GCGGCTACATCGCCTTTCCGGCCGGCATGATGAGCGTGCTGCTGGGCAAGCCGCTGGTGCTGCATGAACAGAACTCCGTG
GCGGGCATGGTCAACAAGGTGCTGGCCGGCGTGGCAGATCGTGTCTTCACGGCCTTCCCCGGCGTGTTCAGGAAAGCCGA
ATGGATCGGCAACCCCCTGCGCCCCGCCTTCATCCGCCAGCCGGACCCTGCAACCCGATTTGCGGGCCGGGCAGGGCCCC
TGAAGCTGCTGGTGGTCGGTGGCAGCCTCGGGGCCAAGGCCCTGAATGAGCTGGTGCCCAGAGCCCTGGCCCTGATGCCG
CCAGCCCAGCGCCCCGACGTCACGCATCAAAGCGGGATCCGCCAGATCGACGAATTGCGTGCCAACTATGCAGCCGCCGG
CGTGCAGGCAGAACTGACGCCCTTCATTGAGGACACTGCACAGGCATTTGCCGATGCCGACCTCATCATTTGCCGCGCTG
GCGCCAGCACCGTCACTGAAATTGCCGCCGTGGGGGCTGCAGCGCTGTTTGTGCCCTTTCCTTCTGCGGTCGATGACCAC
CAGACGACGAATGCCCGGTTCCTGGTCGACCAGGGGGGCGGCTGGTTGCTGCAGCAGCGCGACATGAGCGCCGCCGCACT
GGCCGACATGCTACAAAAAACAGATCGATCCGCGCTGCTTCAATGCGCGCTAAAAGCCAAAACCATGCAAAAAACCGATG
CCACAACGCGCGTTGTGGCTGCTTGCGAGGAGCTTGCAAGATGA

Upstream 100 bases:

>100_bases
TGAGCTACGGCGGCTCGGCCATTTTGATGAACCTGATTGCCTTGGCCGTGGTGCTGCGGATTGACTACGAGAATCGCACC
CTGATGCGTGGGGGGCGGGC

Downstream 100 bases:

>100_bases
AACACGCCATCAAAAACATTCACTTCATCGGGCTGGGCGGCTCCGGCATGTCAGGCATTGCCGAAGTGCTGCACAACCTG
GGTTACGTCATTTCGGGATC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSEHVRSAGPPQASTAPSGGSAVHEVTSVGARVALVMAGGTGGHIFPGLAVAEALRERGWRVHWLGGRGNAGHPSMESQL
VPPRGFAFESIDFSGVRGKGPLTLVFLPLRLLKAFWQSIQVVRRVKPDVVVGLGGYIAFPAGMMSVLLGKPLVLHEQNSV
AGMVNKVLAGVADRVFTAFPGVFRKAEWIGNPLRPAFIRQPDPATRFAGRAGPLKLLVVGGSLGAKALNELVPRALALMP
PAQRPDVTHQSGIRQIDELRANYAAAGVQAELTPFIEDTAQAFADADLIICRAGASTVTEIAAVGAAALFVPFPSAVDDH
QTTNARFLVDQGGGWLLQQRDMSAAALADMLQKTDRSALLQCALKAKTMQKTDATTRVVAACEELAR

Sequences:

>Translated_387_residues
MSEHVRSAGPPQASTAPSGGSAVHEVTSVGARVALVMAGGTGGHIFPGLAVAEALRERGWRVHWLGGRGNAGHPSMESQL
VPPRGFAFESIDFSGVRGKGPLTLVFLPLRLLKAFWQSIQVVRRVKPDVVVGLGGYIAFPAGMMSVLLGKPLVLHEQNSV
AGMVNKVLAGVADRVFTAFPGVFRKAEWIGNPLRPAFIRQPDPATRFAGRAGPLKLLVVGGSLGAKALNELVPRALALMP
PAQRPDVTHQSGIRQIDELRANYAAAGVQAELTPFIEDTAQAFADADLIICRAGASTVTEIAAVGAAALFVPFPSAVDDH
QTTNARFLVDQGGGWLLQQRDMSAAALADMLQKTDRSALLQCALKAKTMQKTDATTRVVAACEELAR
>Mature_386_residues
SEHVRSAGPPQASTAPSGGSAVHEVTSVGARVALVMAGGTGGHIFPGLAVAEALRERGWRVHWLGGRGNAGHPSMESQLV
PPRGFAFESIDFSGVRGKGPLTLVFLPLRLLKAFWQSIQVVRRVKPDVVVGLGGYIAFPAGMMSVLLGKPLVLHEQNSVA
GMVNKVLAGVADRVFTAFPGVFRKAEWIGNPLRPAFIRQPDPATRFAGRAGPLKLLVVGGSLGAKALNELVPRALALMPP
AQRPDVTHQSGIRQIDELRANYAAAGVQAELTPFIEDTAQAFADADLIICRAGASTVTEIAAVGAAALFVPFPSAVDDHQ
TTNARFLVDQGGGWLLQQRDMSAAALADMLQKTDRSALLQCALKAKTMQKTDATTRVVAACEELAR

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=354, Percent_Identity=44.9152542372881, Blast_Score=279, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_POLSJ (Q12EL5)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_547925.1
- ProteinModelPortal:   Q12EL5
- SMR:   Q12EL5
- STRING:   Q12EL5
- GeneID:   4012062
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_1075
- NMPDR:   fig|296591.1.peg.3330
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q12EL5
- ProtClustDB:   PRK00726
- BioCyc:   PSP296591:BPRO_1075-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 40824; Mature: 40692

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHVRSAGPPQASTAPSGGSAVHEVTSVGARVALVMAGGTGGHIFPGLAVAEALRERGW
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCC
RVHWLGGRGNAGHPSMESQLVPPRGFAFESIDFSGVRGKGPLTLVFLPLRLLKAFWQSIQ
EEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
VVRRVKPDVVVGLGGYIAFPAGMMSVLLGKPLVLHEQNSVAGMVNKVLAGVADRVFTAFP
HHHHCCCCEEEECCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHH
GVFRKAEWIGNPLRPAFIRQPDPATRFAGRAGPLKLLVVGGSLGAKALNELVPRALALMP
HHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCC
PAQRPDVTHQSGIRQIDELRANYAAAGVQAELTPFIEDTAQAFADADLIICRAGASTVTE
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
IAAVGAAALFVPFPSAVDDHQTTNARFLVDQGGGWLLQQRDMSAAALADMLQKTDRSALL
HHHHHHHHEEECCCCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHH
QCALKAKTMQKTDATTRVVAACEELAR
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEHVRSAGPPQASTAPSGGSAVHEVTSVGARVALVMAGGTGGHIFPGLAVAEALRERGW
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCC
RVHWLGGRGNAGHPSMESQLVPPRGFAFESIDFSGVRGKGPLTLVFLPLRLLKAFWQSIQ
EEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
VVRRVKPDVVVGLGGYIAFPAGMMSVLLGKPLVLHEQNSVAGMVNKVLAGVADRVFTAFP
HHHHCCCCEEEECCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHH
GVFRKAEWIGNPLRPAFIRQPDPATRFAGRAGPLKLLVVGGSLGAKALNELVPRALALMP
HHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCC
PAQRPDVTHQSGIRQIDELRANYAAAGVQAELTPFIEDTAQAFADADLIICRAGASTVTE
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
IAAVGAAALFVPFPSAVDDHQTTNARFLVDQGGGWLLQQRDMSAAALADMLQKTDRSALL
HHHHHHHHEEECCCCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHH
QCALKAKTMQKTDATTRVVAACEELAR
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA